Vue transversale de la maladie
Migraine
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
Périmètre
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1236 résultats correspondants
· 45 visibles sur cette page
dans le périmètre Migraine
Niveau clinique
Études et traitements 570
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Lumishade® Active Lens NCT04904328 · A Proof of Concept Alleviating the Symptoms of Photosensitive Migraine. | Migraine | Traitement symptomatique | Non applicable | UNKNOWN | This proof of concept clinical study will investigate the efficacy of acti… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:23 | Détail |
| Nerivio Migra-1 active device NCT03361423 · Evaluation of a Novel Device for Treatment of Migraine Headache | Migraine | Traitement symptomatique | Non applicable | COMPLETED | Migraine is a common neurologic with attacks of headache and associated sy… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:23 | Détail |
| Atogepant NCT03939312 · Extension Study to Evaluate the Long-Term Safety and Tolerability of Oral Atogep… | Migraine | Traitement symptomatique | Phase 3 | COMPLETED | A migraine attack is a moderate or severe headache that usually occurs on… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| Atogepant NCT03777059 · 12-Week Placebo-controlled Study of Atogepant for the Preventive Treatment of Mi… | Migraine | Traitement symptomatique | Phase 3 | COMPLETED | A migraine attack is a moderate or severe headache that usually occurs on… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| CGRP NCT01924052 · CGRP Induced Migraine Attacks in Patients With High and Low Genetic Load | Migraine | À vérifier | Non applicable | COMPLETED | The investigators hypothesized that migraine without patients with many ge… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| Dihydroergotamine NCT05337254 · A Study of the PK and Safety of Single Doses of STS101, DHE Injection and Nasal… | Migraine | À vérifier | Phase 1 | COMPLETED | Study STS101-007 is a randomized, double-blind, parallel group, placebo-co… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| Erenumab NCT05281770 · Monoclonal CGRP Antibodies for Migraine Prevention - a Nationwide Real Life Study | Migraine | Traitement symptomatique | À vérifier | UNKNOWN | The primary objective of this study is to evaluate the treatment benefit o… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| Lasmiditan NCT03962738 · MONONOFU — A Study Lasmiditan (LY573144) in a Single Migraine Attack in Japanese… | Migraine | À vérifier | Phase 2 | COMPLETED | The purpose of this study is to evaluate the efficacy and safety of a rang… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| MINDKIDS — Mindfulness for Adolescents for CM and HFEM NCT04968093 · NCT04968093 | Migraine | Ralentissement de la progression | Non applicable | COMPLETED | Chronic Migraine (CM) and High Frequency Episodic Migraine (HFEM) without… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| Optical coherence tomography (OCT) NCT05332431 · Optical Coherence Tomography Findings in Migraine | Migraine | À vérifier | À vérifier | UNKNOWN | This study aims to detect changes in RNFL thickness in patients with diffe… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| PERCAM — Brain Perfusion Assessment in the Acute Phase of Migraine Au… NCT03821584 · NCT03821584 | Migraine | À vérifier | À vérifier | TERMINATED | The aim of the study is to determine the proportion of patients with chang… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| Rimegepant NCT03266588 · Open Label Safety Study in Acute Treatment of Migraine | Migraine | À vérifier | Phase 2/3 | COMPLETED | The purpose of this study is to evaluate safety and tolerability of BHV-30… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| Rimegepant NCT03237845 · Safety and Efficacy in Adult Subjects With Acute Migraines | Migraine | À vérifier | Phase 3 | COMPLETED | The purpose of this study is to evaluate safety and tolerability of BHV-30… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| Rimegepant NCT03235479 · Safety and Efficacy Study in Adult Subjects With Acute Migraines | Migraine | À vérifier | Phase 3 | COMPLETED | The purpose of this study is to evaluate safety and tolerability of BHV-30… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| Sildenafil NCT02795351 · Induction of Migraine Aura With Sildenafil | Migraine | À vérifier | Phase 1 | COMPLETED | This study is done to evaluate whether treatment with the drug sildenafil… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| Tailored Digital Treatment for Migraine NCT05617339 · NCT05617339 | Migraine | Traitement symptomatique · Thérapie génique | Non applicable | UNKNOWN | Background: An individualized internet-based treatment program from a biop… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| Transcutaneous Supraorbital Nerve Stimulator NCT05516251 · Transcutaneous Supraorbital Nerve Stimulator Versus Topiramate in Prevention of… | Migraine | À vérifier | Non applicable | UNKNOWN | Migraine has been ranked as the second most disabling neurological disorde… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| Levcromakalim NCT04905654 · Migraine Inducing Effect of Levcromakalim in Patients With Migraine With Aura | Migraine | À vérifier | Non applicable | COMPLETED | This study aims to explore the effect of Ivabradine on Levcromakalim-induc… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:21 | Détail |
| Biofeedback NCT05454319 · CER-MIG-1 — Cerebri Biofeedback Feasibility Trial | Migraine | Thérapie génique | Non applicable | COMPLETED | The purpose of this study is to investigate feasibility, usability, safety… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:20 | Détail |
| DFN-15 Active NCT03006276 · Efficacy, Tolerability, and Safety Study of DFN-15 | Migraine | À vérifier | Phase 3 | COMPLETED | Efficacy, Tolerability, and Safety of DFN-15 in episodic migraine with or… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:20 | Détail |
Découverte scientifique
Recherches et trouvailles 0
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune trouvaille ne correspond aux filtres. | |||||||
Bibliographie
Publications 661
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Efficacy of Greater Occipital Nerve Blockade in Craniofacial Neuralgi… Greater Occipital Nerve Block with dexamethasone and lidocaine · PMID 40725724 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source : Greater occipital nerve blockade (GONB) is a minimally invasive intervention used to treat primary headaches. However… | Journal of clinical medicine 2026-08-08 00:59:43 | Source |
| Greater occipital nerve blockade for the preventive treatment of chro… Greater Occipital Nerve Block with 0.9% saline · PMID 36739512 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Greater occipital nerve blockade for the prevention of chronic migraine has a limited evidence base. A robust randomize… | Cephalalgia : an international journal of headache 2026-08-08 00:59:43 | Source |
| Three men in a boat: The comparison of the combination therapy of bot… Greater Occipital Nerve Block with 0.9% saline · PMID 36731164 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source This study compared the impact of the combination therapy of onabotulinum toxin A and greater occipital nerve block (Go… | Clinical neurology and neurosurgery 2026-08-08 00:59:43 | Source |
| High dosage accelerated intermittent theta burst stimulation without… tDCS device from neuroConn · PMID 40705070 | Migraine | À vérifier | Publication | PubMed | Voir la publication source High dosage accelerated intermittent theta-burst stimulation (aiTBS) protocols (10 sessions per day for 5 days) combine… | European archives of psychiatry and clinical neuroscie… 2026-08-08 00:59:42 | Source |
| Report Approval for Transcranial Electrical Stimulation (RATES): expe… tDCS device from neuroConn · PMID 41044265 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Transcranial electrical stimulation (tES) has gained substantial momentum as a research and therapeutic tool; however,… | Nature protocols 2026-08-08 00:59:42 | Source |
| Artificial intelligence-based decision support in simulated free flap… Migraine surgery · PMID 42326044 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Free flap compromise after head and neck reconstruction requires rapid recognition and structured escalation. Large lan… | JPRAS open 2026-08-08 00:59:41 | Source |
| Corrugator Supercilii Muscle and Its Relationship with Neurovascular… Migraine surgery · PMID 42192010 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source The corrugator supercilii muscle (CSM) is a critical anatomical target for botulinum toxin injections and surgical inte… | Aesthetic plastic surgery 2026-08-08 00:59:41 | Source |
| Efficacy and tolerability of combination treatment of topiramate and… PROMPT-IN — A Study of Prophylaxis for Migraine Patients With Topiramate in India · PMID 35259… | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source To compare the efficacy and tolerability of combination treatment of topiramate and greater occipital nerve block to to… | Cephalalgia : an international journal of headache 2026-08-08 00:59:40 | Source |
| Vitamin D Deficiency and Supplementation in Migraine: A Scoping Revie… PROMPT-IN — A Study of Prophylaxis for Migraine Patients With Topiramate in India · PMID 41233… | Migraine | Ralentissement de la progression · Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Migraine is a debilitating neurological disorder affecting 10%-20% of the global population, with significant socioecon… | Annals of Indian Academy of Neurology 2026-08-08 00:59:40 | Source |
| A Phase I, Randomized, Single‑Blind, Placebo‑Controlled, Single Ascen… Part B: TRV250 Dose 1 · PMID 32676977 | Migraine | À vérifier | Publication | PubMed | Voir la publication source The delta opioid receptor (DOR) has been identified as a therapeutic target for migraine, with DOR agonists exhibiting… | CNS drugs 2026-08-08 00:59:37 | Source |
| Investigation of a foodborne outbreak of Shigella sonnei in Ireland a… Part A: TRV250-20mg/ml · PMID 32120067 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source To describe a cross-border foodborne outbreak of Shigella sonnei that occurred in Ireland and Northern Ireland (NI) in… | Public health 2026-08-08 00:59:36 | Source |
| Outbreak of hepatitis A infection associated with the consumption of… Part A: TRV250-20mg/ml · PMID 25375902 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source In May 2013, a European alert was issued regarding a hepatitis A virus (HAV) outbreak in Italy. In June 2013, HAV subge… | Euro surveillance : bulletin Europeen sur les maladies… 2026-08-08 00:59:36 | Source |
| Alterations of Resting-State Locus Coeruleus Functional Connectivity… Cefaly device · PMID 35619611 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Transdermal trigeminal electrical neuromodulation (TTEN) is a novel treatment modality that is known for noradrenergic… | Frontiers in psychiatry 2026-08-08 00:59:33 | Source |
| Efficacy of ultrasound-guided greater occipital nerve pulsed radiofre… Efficacy of Greater Occipital Nerve Radiofrequency for Refractory Migraine Treatment · PMID 35… | Migraine | Ralentissement de la progression · Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Ultrasound (US) guided pulsed radiofrequency (PRF) therapy can be used on the greater occipital nerve (GON) in patients… | Acta neurologica Belgica 2026-08-08 00:59:33 | Source |
| Evidence-Based Patient Selection in Headache Surgery: Impact of Preop… Efficacy of Greater Occipital Nerve Radiofrequency for Refractory Migraine Treatment · PMID 36… | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Radiofrequency ablation (RFA) of the greater occipital nerve (GON) is a minimally invasive treatment option commonly us… | Plastic and reconstructive surgery 2026-08-08 00:59:33 | Source |
| Peripheral Neuromodulation for the Management of Headache. Cefaly device · PMID 34150578 | Migraine | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Neuromodulation is an expanding field of study for headache treatment to reduce pain by targeting structures within the… | Anesthesiology and pain medicine 2026-08-08 00:59:33 | Source |
| Phentermine/Topiramate in Obese, Diabetic Uric Acid Stone Formers: An… Topiramate 100 mg · PMID 42361212 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source The purpose of this study was to determine whether medical treatment of obesity, diabetes, and low urine pH with combin… | The Journal of urology 2026-08-08 00:59:31 | Source |
| Use of obesity medications in a young pediatric patient with optic ne… Topiramate 100 mg · PMID 40698016 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Pediatric obesity presents complex challenges in children with underlying endocrine disorders. In patients with optic n… | Obesity pillars 2026-08-08 00:59:31 | Source |
| Atogepant Reduces Psychological Dependence on Acute Treatments Evalua… Atogepant 60 mg · PMID 42494172 | Migraine | À vérifier | Publication | PubMed | Voir la publication source The Leeds Dependence Questionnaire (LDQ) is a validated tool for assessing psychological dependence across various subs… | Brain and behavior 2026-08-08 00:59:30 | Source |
| Blood pressure lowering for prevention of episodic migraine: results… Propranolol 160 mg · PMID 41036277 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Beta blockers are effective in migraine prevention. Low-dose combination therapy of blood pressure lowering is likely t… | Frontiers in neurology 2026-08-08 00:59:30 | Source |
Exploration — prudence
Pistes exploratoires 5
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Bavisant BRAVEinMS — Bavisant | Migraine | Remyélinisation · Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Antagonisme du récepteur H3 de l’histamine Bavisant est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migra… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| Tol-MP Tol-MP — tolérance immunitaire spécifique de la myéline | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Microparticules biodégradables chargées en rapamycine et fonctionnalisées… Tol-MP est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migrain… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| SetPoint System SetPoint System — SetPoint Medical | Migraine | Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | re ApplicationsPublicationsCompanyCareersNewsGet startedGet startedNewsThe… SetPoint System est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation immunométabolique de la microglie 4-octyl itaconate et dérivés est étudié dans Sclérose latérale amyotrophique et documente plusieurs axes biologiques po… | Rapprochement Biomedical Watch · Sclérose latérale amy… | Détail |
| N-PPG N-PPG — modulation métabolique cérébrale | Migraine | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation métabolique et mitohormèse N-PPG est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être pertinents pour Migrai… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |