Vue transversale de la maladie
Migraine
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
Périmètre
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1236 résultats correspondants
· 45 visibles sur cette page
dans le périmètre Migraine
Niveau clinique
Études et traitements 570
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Lumishade® Active Lens NCT04904328 · A Proof of Concept Alleviating the Symptoms of Photosensitive Migraine. | Migraine | Traitement symptomatique | Non applicable | UNKNOWN | This proof of concept clinical study will investigate the efficacy of acti… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:23 | Détail |
| Nerivio Migra-1 active device NCT03361423 · Evaluation of a Novel Device for Treatment of Migraine Headache | Migraine | Traitement symptomatique | Non applicable | COMPLETED | Migraine is a common neurologic with attacks of headache and associated sy… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:23 | Détail |
| Atogepant NCT03939312 · Extension Study to Evaluate the Long-Term Safety and Tolerability of Oral Atogep… | Migraine | Traitement symptomatique | Phase 3 | COMPLETED | A migraine attack is a moderate or severe headache that usually occurs on… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| Atogepant NCT03777059 · 12-Week Placebo-controlled Study of Atogepant for the Preventive Treatment of Mi… | Migraine | Traitement symptomatique | Phase 3 | COMPLETED | A migraine attack is a moderate or severe headache that usually occurs on… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| CGRP NCT01924052 · CGRP Induced Migraine Attacks in Patients With High and Low Genetic Load | Migraine | À vérifier | Non applicable | COMPLETED | The investigators hypothesized that migraine without patients with many ge… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| Dihydroergotamine NCT05337254 · A Study of the PK and Safety of Single Doses of STS101, DHE Injection and Nasal… | Migraine | À vérifier | Phase 1 | COMPLETED | Study STS101-007 is a randomized, double-blind, parallel group, placebo-co… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| Erenumab NCT05281770 · Monoclonal CGRP Antibodies for Migraine Prevention - a Nationwide Real Life Study | Migraine | Traitement symptomatique | À vérifier | UNKNOWN | The primary objective of this study is to evaluate the treatment benefit o… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| Lasmiditan NCT03962738 · MONONOFU — A Study Lasmiditan (LY573144) in a Single Migraine Attack in Japanese… | Migraine | À vérifier | Phase 2 | COMPLETED | The purpose of this study is to evaluate the efficacy and safety of a rang… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| MINDKIDS — Mindfulness for Adolescents for CM and HFEM NCT04968093 · NCT04968093 | Migraine | Ralentissement de la progression | Non applicable | COMPLETED | Chronic Migraine (CM) and High Frequency Episodic Migraine (HFEM) without… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| Optical coherence tomography (OCT) NCT05332431 · Optical Coherence Tomography Findings in Migraine | Migraine | À vérifier | À vérifier | UNKNOWN | This study aims to detect changes in RNFL thickness in patients with diffe… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| PERCAM — Brain Perfusion Assessment in the Acute Phase of Migraine Au… NCT03821584 · NCT03821584 | Migraine | À vérifier | À vérifier | TERMINATED | The aim of the study is to determine the proportion of patients with chang… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| Rimegepant NCT03266588 · Open Label Safety Study in Acute Treatment of Migraine | Migraine | À vérifier | Phase 2/3 | COMPLETED | The purpose of this study is to evaluate safety and tolerability of BHV-30… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| Rimegepant NCT03237845 · Safety and Efficacy in Adult Subjects With Acute Migraines | Migraine | À vérifier | Phase 3 | COMPLETED | The purpose of this study is to evaluate safety and tolerability of BHV-30… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| Rimegepant NCT03235479 · Safety and Efficacy Study in Adult Subjects With Acute Migraines | Migraine | À vérifier | Phase 3 | COMPLETED | The purpose of this study is to evaluate safety and tolerability of BHV-30… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| Sildenafil NCT02795351 · Induction of Migraine Aura With Sildenafil | Migraine | À vérifier | Phase 1 | COMPLETED | This study is done to evaluate whether treatment with the drug sildenafil… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| Tailored Digital Treatment for Migraine NCT05617339 · NCT05617339 | Migraine | Traitement symptomatique · Thérapie génique | Non applicable | UNKNOWN | Background: An individualized internet-based treatment program from a biop… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| Transcutaneous Supraorbital Nerve Stimulator NCT05516251 · Transcutaneous Supraorbital Nerve Stimulator Versus Topiramate in Prevention of… | Migraine | À vérifier | Non applicable | UNKNOWN | Migraine has been ranked as the second most disabling neurological disorde… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| Levcromakalim NCT04905654 · Migraine Inducing Effect of Levcromakalim in Patients With Migraine With Aura | Migraine | À vérifier | Non applicable | COMPLETED | This study aims to explore the effect of Ivabradine on Levcromakalim-induc… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:21 | Détail |
| Biofeedback NCT05454319 · CER-MIG-1 — Cerebri Biofeedback Feasibility Trial | Migraine | Thérapie génique | Non applicable | COMPLETED | The purpose of this study is to investigate feasibility, usability, safety… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:20 | Détail |
| DFN-15 Active NCT03006276 · Efficacy, Tolerability, and Safety Study of DFN-15 | Migraine | À vérifier | Phase 3 | COMPLETED | Efficacy, Tolerability, and Safety of DFN-15 in episodic migraine with or… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:20 | Détail |
Découverte scientifique
Recherches et trouvailles 0
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune trouvaille ne correspond aux filtres. | |||||||
Bibliographie
Publications 661
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Active machine learning model for the dynamic simulation and growth m… TI-001 · PMID 38184678 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Substrate-catalyzed growth offers a highly promising approach for the controlled synthesis of carbon nanostructures. Ho… | Nature communications 2026-08-08 00:59:56 | Source |
| Combined Occipital Nerve and Sphenopalatine Ganglion Neuromodulation… Occipital Nerve Stimulation · PMID 42100751 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Craniofacial complex regional pain syndrome (CRPS) is a rare, diagnostically challenging condition characterized by sym… | Local and regional anesthesia 2026-08-08 00:59:56 | Source |
| Comparative Efficacy and Acceptability of Noninvasive Brain Stimulati… Occipital Nerve Stimulation · PMID 42473074 | Migraine | À vérifier | Publication | PubMed | Voir la publication source This network meta-analysis (NMA) aimed to compare and rank the efficacy and acceptability of different noninvasive brai… | Brain and behavior 2026-08-08 00:59:56 | Source |
| TiO2 nanotubes: interdependence of substrate grain orientation and gr… TI-001 · PMID 25545715 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Highly ordered arrays of TiO2 nanotubes can be produced by self-organized anodic growth. It is desirable to identify ke… | ACS applied materials & interfaces 2026-08-08 00:59:56 | Source |
| International Headache society evidence-based guidelines on the use o… Nerivio Migra-1 Sham device · PMID 41117312 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source ObjectiveTo develop evidence-based clinical practice guidelines for non-invasive neuromodulation devices in acute and p… | Cephalalgia : an international journal of headache 2026-08-08 00:59:54 | Source |
| Plasma Phosphorylated Tau 217 in Participants at Risk for Chronic Tra… BE WELL With Migraine: Brain Education and WELLness With Migraine · PMID 42440317 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source In vivo biomarkers for detecting neuropathologies from repetitive head impacts (RHI), including chronic traumatic encep… | JAMA network open 2026-08-08 00:59:53 | Source |
| Weight loss with atogepant in the long-term treatment of migraine: An… BE WELL With Migraine: Brain Education and WELLness With Migraine · PMID 42396885 | Migraine | À vérifier | Publication | PubMed | Voir la publication source To assess weight loss with atogepant 60 mg once daily during long-term treatment of chronic migraine (CM) and episodic… | Headache 2026-08-08 00:59:53 | Source |
| Cellulose and Its Derivatives in Drug Delivery: Recent Advances and A… sumatriptan succinate · PMID 42198288 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Drug delivery systems have long faced a fundamental challenge: achieving high drug-loading efficiency, precise control… | Pharmaceutics 2026-08-08 00:59:51 | Source |
| Spatial metabolomics combined with MALDI-MSI unveils gut-brain axis m… sumatriptan succinate · PMID 41619552 | Migraine | Immunomodulation · Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Migraine is a highly disabling neurological disorder characterized by recurrent headaches and complex metabolic disturb… | Phytomedicine : international journal of phytotherapy… 2026-08-08 00:59:51 | Source |
| Drugs targeting nitric oxide synthase for migraine treatment. NXN-188 · PMID 24818644 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Ample evidence that nitric oxide (NO) is a causative molecule in migraine has encouraged research to develop drugs that… | Expert opinion on investigational drugs 2026-08-08 00:59:50 | Source |
| The nitric oxide synthase inhibitor and serotonin-receptor agonist NX… NXN-188 · PMID 29913885 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Background and aims NXN-188 is a combined neuronal nitric oxide synthase (nNOS) inhibitor and 5HT-1B/1D receptor agonis… | Scandinavian journal of pain 2026-08-08 00:59:50 | Source |
| Identifying central positional vertigo to prevent diagnostic pitfalls… Vestibular System in Migrainous Vertigo Patients · PMID 42564662 | Migraine | À vérifier | Publication | PubMed | Voir la publication source This case series highlights the critical role of radiological imaging in patients presenting with positional vertigo in… | Radiology case reports 2026-08-08 00:59:48 | Source |
| Quantitative pupillometry as a marker of autonomic dysregulation in v… Vestibular System in Migrainous Vertigo Patients · PMID 42548108 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source Vestibular migraine (VM) has been associated with altered central sensory processing; however, objective measures of au… | Journal of oral & facial pain and headache 2026-08-08 00:59:48 | Source |
| Arterial hepatic perfusion is preserved during early resuscitation af… blood withdrawal · PMID 42431156 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Hemorrhagic shock is a major contributor to morbidity and mortality after polytrauma and plays a central role in the de… | Injury 2026-08-08 00:59:47 | Source |
| Long peripheral catheters for short-term vascular access: A 7-day obs… blood withdrawal · PMID 42438309 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source Long peripheral catheters are increasingly used as an alternative to short peripheral catheters for short-term intraven… | The journal of vascular access 2026-08-08 00:59:47 | Source |
| A Real-World Evidence Study on US Patients Demonstrating Safety of Hi… Nerivio ® · PMID 41886224 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Remote electrical neuromodulation (REN) is an FDA-cleared, nonsignificant-risk, drug-free, prescribed wearable device (… | Pain and therapy 2026-08-08 00:59:45 | Source |
| Association of adverse childhood experiences with physical illness an… Brief Interventions in Chronic Migraine · PMID 40194777 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Adverse childhood experiences (ACEs) are highly prevalent and associated with life-long health consequences. Here, we i… | European journal of public health 2026-08-08 00:59:45 | Source |
| Non-Pharmacological Treatment of Primary Headaches-A Focused Review. Brief Interventions in Chronic Migraine · PMID 37891800 | Migraine | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Headache disorders are a significant global health burden, leading to reduced quality of life. While vast pharmacologic… | Brain sciences 2026-08-08 00:59:45 | Source |
| U.S. Veterans Using Remote Electrical Neuromodulation for Migraine: A… Nerivio ® · PMID 42520312 | Migraine | Ralentissement de la progression · Traitement symptomatique | Publication | PubMed | Voir la publication source Among U.S. veterans, migraine and other headache disorders are common, and frequently co-occur with other comorbidities… | Military medicine 2026-08-08 00:59:45 | Source |
| 2025 guideline update to acute treatment of migraine for adults in th… Greater Occipital Nerve Block with dexamethasone and lidocaine · PMID 41321235 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source To update the 2016 American Headache Society (AHS) guideline on parenteral pharmacologic therapies for the management o… | Headache 2026-08-08 00:59:43 | Source |
Exploration — prudence
Pistes exploratoires 5
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Bavisant BRAVEinMS — Bavisant | Migraine | Remyélinisation · Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Antagonisme du récepteur H3 de l’histamine Bavisant est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migra… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| Tol-MP Tol-MP — tolérance immunitaire spécifique de la myéline | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Microparticules biodégradables chargées en rapamycine et fonctionnalisées… Tol-MP est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migrain… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| SetPoint System SetPoint System — SetPoint Medical | Migraine | Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | re ApplicationsPublicationsCompanyCareersNewsGet startedGet startedNewsThe… SetPoint System est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation immunométabolique de la microglie 4-octyl itaconate et dérivés est étudié dans Sclérose latérale amyotrophique et documente plusieurs axes biologiques po… | Rapprochement Biomedical Watch · Sclérose latérale amy… | Détail |
| N-PPG N-PPG — modulation métabolique cérébrale | Migraine | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation métabolique et mitohormèse N-PPG est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être pertinents pour Migrai… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |