Vue transversale de la maladie
Migraine
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
Périmètre
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1236 résultats correspondants
· 45 visibles sur cette page
dans le périmètre Migraine
Niveau clinique
Études et traitements 570
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Lumishade® Active Lens NCT04904328 · A Proof of Concept Alleviating the Symptoms of Photosensitive Migraine. | Migraine | Traitement symptomatique | Non applicable | UNKNOWN | This proof of concept clinical study will investigate the efficacy of acti… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:23 | Détail |
| Nerivio Migra-1 active device NCT03361423 · Evaluation of a Novel Device for Treatment of Migraine Headache | Migraine | Traitement symptomatique | Non applicable | COMPLETED | Migraine is a common neurologic with attacks of headache and associated sy… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:23 | Détail |
| Atogepant NCT03939312 · Extension Study to Evaluate the Long-Term Safety and Tolerability of Oral Atogep… | Migraine | Traitement symptomatique | Phase 3 | COMPLETED | A migraine attack is a moderate or severe headache that usually occurs on… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| Atogepant NCT03777059 · 12-Week Placebo-controlled Study of Atogepant for the Preventive Treatment of Mi… | Migraine | Traitement symptomatique | Phase 3 | COMPLETED | A migraine attack is a moderate or severe headache that usually occurs on… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| CGRP NCT01924052 · CGRP Induced Migraine Attacks in Patients With High and Low Genetic Load | Migraine | À vérifier | Non applicable | COMPLETED | The investigators hypothesized that migraine without patients with many ge… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| Dihydroergotamine NCT05337254 · A Study of the PK and Safety of Single Doses of STS101, DHE Injection and Nasal… | Migraine | À vérifier | Phase 1 | COMPLETED | Study STS101-007 is a randomized, double-blind, parallel group, placebo-co… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| Erenumab NCT05281770 · Monoclonal CGRP Antibodies for Migraine Prevention - a Nationwide Real Life Study | Migraine | Traitement symptomatique | À vérifier | UNKNOWN | The primary objective of this study is to evaluate the treatment benefit o… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| Lasmiditan NCT03962738 · MONONOFU — A Study Lasmiditan (LY573144) in a Single Migraine Attack in Japanese… | Migraine | À vérifier | Phase 2 | COMPLETED | The purpose of this study is to evaluate the efficacy and safety of a rang… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| MINDKIDS — Mindfulness for Adolescents for CM and HFEM NCT04968093 · NCT04968093 | Migraine | Ralentissement de la progression | Non applicable | COMPLETED | Chronic Migraine (CM) and High Frequency Episodic Migraine (HFEM) without… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| Optical coherence tomography (OCT) NCT05332431 · Optical Coherence Tomography Findings in Migraine | Migraine | À vérifier | À vérifier | UNKNOWN | This study aims to detect changes in RNFL thickness in patients with diffe… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| PERCAM — Brain Perfusion Assessment in the Acute Phase of Migraine Au… NCT03821584 · NCT03821584 | Migraine | À vérifier | À vérifier | TERMINATED | The aim of the study is to determine the proportion of patients with chang… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| Rimegepant NCT03266588 · Open Label Safety Study in Acute Treatment of Migraine | Migraine | À vérifier | Phase 2/3 | COMPLETED | The purpose of this study is to evaluate safety and tolerability of BHV-30… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| Rimegepant NCT03237845 · Safety and Efficacy in Adult Subjects With Acute Migraines | Migraine | À vérifier | Phase 3 | COMPLETED | The purpose of this study is to evaluate safety and tolerability of BHV-30… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| Rimegepant NCT03235479 · Safety and Efficacy Study in Adult Subjects With Acute Migraines | Migraine | À vérifier | Phase 3 | COMPLETED | The purpose of this study is to evaluate safety and tolerability of BHV-30… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| Sildenafil NCT02795351 · Induction of Migraine Aura With Sildenafil | Migraine | À vérifier | Phase 1 | COMPLETED | This study is done to evaluate whether treatment with the drug sildenafil… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| Tailored Digital Treatment for Migraine NCT05617339 · NCT05617339 | Migraine | Traitement symptomatique · Thérapie génique | Non applicable | UNKNOWN | Background: An individualized internet-based treatment program from a biop… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| Transcutaneous Supraorbital Nerve Stimulator NCT05516251 · Transcutaneous Supraorbital Nerve Stimulator Versus Topiramate in Prevention of… | Migraine | À vérifier | Non applicable | UNKNOWN | Migraine has been ranked as the second most disabling neurological disorde… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| Levcromakalim NCT04905654 · Migraine Inducing Effect of Levcromakalim in Patients With Migraine With Aura | Migraine | À vérifier | Non applicable | COMPLETED | This study aims to explore the effect of Ivabradine on Levcromakalim-induc… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:21 | Détail |
| Biofeedback NCT05454319 · CER-MIG-1 — Cerebri Biofeedback Feasibility Trial | Migraine | Thérapie génique | Non applicable | COMPLETED | The purpose of this study is to investigate feasibility, usability, safety… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:20 | Détail |
| DFN-15 Active NCT03006276 · Efficacy, Tolerability, and Safety Study of DFN-15 | Migraine | À vérifier | Phase 3 | COMPLETED | Efficacy, Tolerability, and Safety of DFN-15 in episodic migraine with or… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:20 | Détail |
Découverte scientifique
Recherches et trouvailles 0
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune trouvaille ne correspond aux filtres. | |||||||
Bibliographie
Publications 661
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| The impact of timing, dosage, and duration of high-dose methylprednis… Methylprednisolone sodium succinate · PMID 42240612 | Migraine | À vérifier | Publication | PubMed | Voir la publication source The role of high-dose methylprednisolone sodium succinate (MPSS) in acute traumatic spinal cord injury (SCI) remains co… | The journal of spinal cord medicine 2026-08-08 01:00:09 | Source |
| Exploring the Sensitivity Limits of Neuronal Current Imaging With MRI… Visual Stimulation · PMID 42565248 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source Conventional BOLD-fMRI relies on hemodynamic responses that are temporally and spatially indirect markers of neural act… | Human brain mapping 2026-08-08 01:00:07 | Source |
| Investigating the Time-Course of Verticality Sensitivity Changes Duri… Visual Stimulation · PMID 42562383 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Verticality perception is a multisensory process that relies primarily on visual and vestibular input. Previous studies… | Multisensory research 2026-08-08 01:00:07 | Source |
| Evaluating clinical associations of immediate post-traumatic headache… Prospective ED Headache Cohort Study · PMID 42563150 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source Post-traumatic headache (PTH) is a frequent early consequence of head traumatic injury, yet emergency departments (EDs)… | The journal of headache and pain 2026-08-08 01:00:06 | Source |
| Retinal layers prognosticate cognitive progression independent of rel… Prospective ED Headache Cohort Study · PMID 42562954 | Migraine | Neuroprotection · Ralentissement de la progression · Thérapie génique | Publication | PubMed | Voir la publication source Optical coherence tomography (OCT) quantifies retinal neuroaxonal loss related to neurodegeneration in people with mult… | Journal of neurology 2026-08-08 01:00:06 | Source |
| Chronic xenogeneic GVHD after CAR T cell therapy limits long-term saf… antibodies against calcitonin-gene related peptide or its receptor · PMID 42566762 | Migraine | Immunomodulation · Thérapie cellulaire | Publication | PubMed | Voir la publication source The clinical successes of chimeric antigen receptor (CAR) T cells represent a major shift in immunotherapy. However, th… | Blood advances 2026-08-08 01:00:05 | Source |
| Comparative analyses of olfactory receptor repertoires in Schizothora… antibodies against calcitonin-gene related peptide or its receptor · PMID 42566844 | Migraine | À vérifier | Publication | PubMed | Voir la publication source The olfactory receptor (OR) genes constitute the molecular basis of fish olfaction, mediating survival behaviors and en… | Comparative biochemistry and physiology. Part D, Genom… 2026-08-08 01:00:05 | Source |
| Digital Remote Assessment of Motor and Speech Changes in Amyotrophic… Click Digital Therapeutic · PMID 42531420 | Migraine | Ralentissement de la progression · Thérapie génique | Publication | PubMed | Voir la publication source Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease with an active trial landscape that relies on the se… | JMIR formative research 2026-08-08 01:00:04 | Source |
| Short dextran-solanesol block copolymer as a bio-based platform for m… Click Digital Therapeutic · PMID 42493094 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Biohybrid block copolymer micelles from natural components hold great promise for biomedical applications; however, int… | Carbohydrate polymers 2026-08-08 01:00:04 | Source |
| Efficacy of MEDI0618, a pH-dependent monoclonal antibody targeting PA… MEDI0618 · PMID 40036725 | Migraine | Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Protease activated receptor 2 (PAR2) is a G-protein coupled receptor expressed in meningeal neurons, fibroblasts and ma… | Brain : a journal of neurology 2026-08-08 01:00:03 | Source |
| The development of proteinase-activated receptor-2 modulators and the… MEDI0618 · PMID 33242065 | Migraine | Immunomodulation | Publication | PubMed | Voir la publication source Protease-activated receptor-2 (PAR2) has been extensively studied since its discovery in the mid-1990. Despite the adva… | Biochemical Society transactions 2026-08-08 01:00:03 | Source |
| Delivery Model Matters for Digital Interventions in Pain Self-Managem… Care as usual · PMID 42475133 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Digital health interventions can improve access to and outreach of evidence-based support for people living with chroni… | Journal of medical Internet research 2026-08-08 01:00:02 | Source |
| Process Evaluation of a Problem-Solving Intervention with Workplace I… Care as usual · PMID 42541653 | Migraine | À vérifier | Publication | PubMed | Voir la publication source This process evaluation examined the implementation of a problem-solving intervention with workplace involvement (PSI-W… | Journal of occupational rehabilitation 2026-08-08 01:00:02 | Source |
| Ultrasound-Guided Stellate Ganglion Block in Fibromyalgia: A Randomiz… Ultrasound guided Stellate ganglion block · PMID 42530408 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Fibromyalgia is a chronic pain syndrome characterized by widespread pain, fatigue, and sleep disturbance. Many patients… | Pain research & management 2026-08-08 01:00:00 | Source |
| Post-dural Puncture Headache During Bacteraemia: Successful Managemen… ultrasound guided Greater occipital nerve block · PMID 42535063 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Epidural blood patch (EBP) is considered the most effective interventional treatment for post-dural puncture headache (… | Cureus 2026-08-08 00:59:59 | Source |
| Ultrasound-Guided Greater Occipital Nerve Block Across Headache Pheno… ultrasound guided Greater occipital nerve block · PMID 42533183 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Greater occipital nerve blocks (GONBs) are used across headache phenotypes, but short-term effectiveness and predictors… | Pain and therapy 2026-08-08 00:59:59 | Source |
| CGRP-pathway exposure during the pre-EBP interval in spontaneous intr… Galcanezumab · PMID 42432562 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Given hypothesized involvement of calcitonin gene-related peptide (CGRP) in trigeminovascular pain and the frequent mig… | BMC neurology 2026-08-08 00:59:58 | Source |
| Comparing synthetic and biological therapy for the treatment of clust… Galcanezumab · PMID 42493477 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Cluster headache is an extremely painful and severely disabling primary headache disorder that, despite its profound im… | Expert review of neurotherapeutics 2026-08-08 00:59:58 | Source |
| Compound Chamomile and Lidocaine Hydrochloride Gel in Oral Diseases:… Lidocaine Hydrochloride · PMID 42558651 | Migraine | Immunomodulation · Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Oral diseases frequently entail microbial infections or mucosal damage, typically accompanied by pain and discomfort. P… | Drug design, development and therapy 2026-08-08 00:59:57 | Source |
| Impact of Menthol Concentration on Ketoprofen Permeation and Photosta… Lidocaine Hydrochloride · PMID 42518428 | Migraine | Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Topical nonsteroidal anti-inflammatory drugs provide localized pain relief while reducing the risk of systemic adverse… | ACS omega 2026-08-08 00:59:57 | Source |
Exploration — prudence
Pistes exploratoires 5
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Bavisant BRAVEinMS — Bavisant | Migraine | Remyélinisation · Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Antagonisme du récepteur H3 de l’histamine Bavisant est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migra… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| Tol-MP Tol-MP — tolérance immunitaire spécifique de la myéline | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Microparticules biodégradables chargées en rapamycine et fonctionnalisées… Tol-MP est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migrain… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| SetPoint System SetPoint System — SetPoint Medical | Migraine | Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | re ApplicationsPublicationsCompanyCareersNewsGet startedGet startedNewsThe… SetPoint System est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation immunométabolique de la microglie 4-octyl itaconate et dérivés est étudié dans Sclérose latérale amyotrophique et documente plusieurs axes biologiques po… | Rapprochement Biomedical Watch · Sclérose latérale amy… | Détail |
| N-PPG N-PPG — modulation métabolique cérébrale | Migraine | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation métabolique et mitohormèse N-PPG est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être pertinents pour Migrai… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |