Vue transversale de la maladie
Migraine
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
Périmètre
Filtrer toute la vue
Chaque choix s’applique immédiatement aux quatre sections. Le filtre « type de SEP » n’apparaît que lorsque la sclérose en plaques est sélectionnée.
1236 résultats correspondants
· 45 visibles sur cette page
dans le périmètre Migraine
Niveau clinique
Études et traitements 570
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Lumishade® Active Lens NCT04904328 · A Proof of Concept Alleviating the Symptoms of Photosensitive Migraine. | Migraine | Traitement symptomatique | Non applicable | UNKNOWN | This proof of concept clinical study will investigate the efficacy of acti… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:23 | Détail |
| Nerivio Migra-1 active device NCT03361423 · Evaluation of a Novel Device for Treatment of Migraine Headache | Migraine | Traitement symptomatique | Non applicable | COMPLETED | Migraine is a common neurologic with attacks of headache and associated sy… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:23 | Détail |
| Atogepant NCT03939312 · Extension Study to Evaluate the Long-Term Safety and Tolerability of Oral Atogep… | Migraine | Traitement symptomatique | Phase 3 | COMPLETED | A migraine attack is a moderate or severe headache that usually occurs on… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| Atogepant NCT03777059 · 12-Week Placebo-controlled Study of Atogepant for the Preventive Treatment of Mi… | Migraine | Traitement symptomatique | Phase 3 | COMPLETED | A migraine attack is a moderate or severe headache that usually occurs on… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| CGRP NCT01924052 · CGRP Induced Migraine Attacks in Patients With High and Low Genetic Load | Migraine | À vérifier | Non applicable | COMPLETED | The investigators hypothesized that migraine without patients with many ge… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| Dihydroergotamine NCT05337254 · A Study of the PK and Safety of Single Doses of STS101, DHE Injection and Nasal… | Migraine | À vérifier | Phase 1 | COMPLETED | Study STS101-007 is a randomized, double-blind, parallel group, placebo-co… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| Erenumab NCT05281770 · Monoclonal CGRP Antibodies for Migraine Prevention - a Nationwide Real Life Study | Migraine | Traitement symptomatique | À vérifier | UNKNOWN | The primary objective of this study is to evaluate the treatment benefit o… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| Lasmiditan NCT03962738 · MONONOFU — A Study Lasmiditan (LY573144) in a Single Migraine Attack in Japanese… | Migraine | À vérifier | Phase 2 | COMPLETED | The purpose of this study is to evaluate the efficacy and safety of a rang… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| MINDKIDS — Mindfulness for Adolescents for CM and HFEM NCT04968093 · NCT04968093 | Migraine | Ralentissement de la progression | Non applicable | COMPLETED | Chronic Migraine (CM) and High Frequency Episodic Migraine (HFEM) without… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| Optical coherence tomography (OCT) NCT05332431 · Optical Coherence Tomography Findings in Migraine | Migraine | À vérifier | À vérifier | UNKNOWN | This study aims to detect changes in RNFL thickness in patients with diffe… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| PERCAM — Brain Perfusion Assessment in the Acute Phase of Migraine Au… NCT03821584 · NCT03821584 | Migraine | À vérifier | À vérifier | TERMINATED | The aim of the study is to determine the proportion of patients with chang… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| Rimegepant NCT03266588 · Open Label Safety Study in Acute Treatment of Migraine | Migraine | À vérifier | Phase 2/3 | COMPLETED | The purpose of this study is to evaluate safety and tolerability of BHV-30… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| Rimegepant NCT03237845 · Safety and Efficacy in Adult Subjects With Acute Migraines | Migraine | À vérifier | Phase 3 | COMPLETED | The purpose of this study is to evaluate safety and tolerability of BHV-30… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| Rimegepant NCT03235479 · Safety and Efficacy Study in Adult Subjects With Acute Migraines | Migraine | À vérifier | Phase 3 | COMPLETED | The purpose of this study is to evaluate safety and tolerability of BHV-30… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| Sildenafil NCT02795351 · Induction of Migraine Aura With Sildenafil | Migraine | À vérifier | Phase 1 | COMPLETED | This study is done to evaluate whether treatment with the drug sildenafil… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| Tailored Digital Treatment for Migraine NCT05617339 · NCT05617339 | Migraine | Traitement symptomatique · Thérapie génique | Non applicable | UNKNOWN | Background: An individualized internet-based treatment program from a biop… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| Transcutaneous Supraorbital Nerve Stimulator NCT05516251 · Transcutaneous Supraorbital Nerve Stimulator Versus Topiramate in Prevention of… | Migraine | À vérifier | Non applicable | UNKNOWN | Migraine has been ranked as the second most disabling neurological disorde… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:22 | Détail |
| Levcromakalim NCT04905654 · Migraine Inducing Effect of Levcromakalim in Patients With Migraine With Aura | Migraine | À vérifier | Non applicable | COMPLETED | This study aims to explore the effect of Ivabradine on Levcromakalim-induc… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:21 | Détail |
| Biofeedback NCT05454319 · CER-MIG-1 — Cerebri Biofeedback Feasibility Trial | Migraine | Thérapie génique | Non applicable | COMPLETED | The purpose of this study is to investigate feasibility, usability, safety… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:20 | Détail |
| DFN-15 Active NCT03006276 · Efficacy, Tolerability, and Safety Study of DFN-15 | Migraine | À vérifier | Phase 3 | COMPLETED | Efficacy, Tolerability, and Safety of DFN-15 in episodic migraine with or… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:20 | Détail |
Découverte scientifique
Recherches et trouvailles 0
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune trouvaille ne correspond aux filtres. | |||||||
Bibliographie
Publications 661
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Case Report: Anodal DLPFC-tDCS for refractory post-traumatic cognitiv… Galcanezumab · PMID 42602261 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Cognitive fatigue is among the most common and disabling long-term sequelae of mild traumatic brain injury (mTBI), with… | Frontiers in human neuroscience 2026-08-16 19:23:06 | Source |
| High Cervical 10 kHz Spinal Cord Stimulation After Occipital Nerve St… Occipital Nerve Stimulation · PMID 42573543 | Migraine | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source In this retrospective study, we evaluated high-frequency spinal cord stimulation (SCS) as an alternative neuromodulatio… | Neuromodulation : journal of the International Neuromo… 2026-08-16 19:23:03 | Source |
| Global prevalence and disability burden of brain disorders: Impact of… BE WELL With Migraine: Brain Education and WELLness With Migraine · PMID 42269957 | Migraine | Ralentissement de la progression | Publication | PubMed | Voir la publication source Brain disorders-encompassing neurological, mental, and substance use disorders-account for 10 of the top 25 causes of d… | Neuroscience and biobehavioral reviews 2026-08-16 19:22:56 | Source |
| NXN-188, a selective nNOS inhibitor and a 5-HT1B/1D receptor agonist,… NXN-188 · PMID 23155193 | Migraine | À vérifier | Publication | PubMed | Voir la publication source NXN-188 is a combined neuronal nitric oxide synthase (nNOS) inhibitor and 5-hydroxytryptamine 1B/1D (5-HT1B/1D) recepto… | Cephalalgia : an international journal of headache 2026-08-16 19:22:51 | Source |
| Vestibular cortex-related effective connectivity signatures: characte… Vestibular System in Migrainous Vertigo Patients · PMID 42337425 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Neuroimaging studies of vestibular migraine (VM) have revealed abnormal functional connectivity in the central vestibul… | The journal of headache and pain 2026-08-16 19:22:46 | Source |
| Cultured Epidermal Autograft Formation With Reduced Platelet-Rich Pla… blood withdrawal · PMID 42424623 | Migraine | Immunomodulation | Publication | PubMed | Voir la publication source Cultured epidermal autografts (CEA) reportedly have better cosmesis than traditional autografts and are especially usef… | The Journal of craniofacial surgery 2026-08-16 19:22:45 | Source |
| Impact of acute high thoracic spinal cord injury on in vivo vascular… blood withdrawal · PMID 42219075 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Cardiovascular dysfunction is a major cause of morbidity and mortality following high-thoracic spinal cord injury (SCI)… | Experimental neurology 2026-08-16 19:22:45 | Source |
| Practice-Based Consensus Amongst Indian Neurologists: Adopting Remote… Nerivio ® · PMID 41697517 | Migraine | Ralentissement de la progression | Publication | PubMed | Voir la publication source Migraine is a major cause of disability in India, disproportionately affecting women and adolescents. Although traditio… | Advances in therapy 2026-08-16 19:22:41 | Source |
| Ultrasound-guided 5-in-1 trigger point injection for treating tension… Greater Occipital Nerve Block with 0.9% saline · PMID 35945722 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Tension-type headache (TTH) is the most common type of primary headache, and trigger point injection (TPI) is frequentl… | Medicine 2026-08-16 19:22:37 | Source |
| The consequences of the new European reclassification of non-invasive… tDCS device from neuroConn · PMID 38679530 | Migraine | À vérifier | Publication | PubMed | Voir la publication source A significant amount of European basic and clinical neuroscience research includes the use of transcranial magnetic sti… | Clinical neurophysiology : official journal of the Int… 2026-08-16 19:22:35 | Source |
| Prescription of cardiovascular drugs in the French ODIN cohort of hea… Part A: TRV250-20mg/ml · PMID 24388162 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Chronic heart failure (CHF) is a frequent severe disease. Disease-management programmes, which contain a therapeutic pa… | Archives of cardiovascular diseases 2026-08-16 19:22:24 | Source |
| Socioeconomic factors and mortality in diastolic heart failure. Part A: TRV250-20mg/ml · PMID 24467732 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Mortality in patients with heart failure with preserved ejection fraction (HFPEF) has remained stable over recent decad… | European journal of clinical investigation 2026-08-16 19:22:24 | Source |
| [Neurostimulation of the supraorbital nerve with the Cefaly device -… Cefaly device · PMID 31089108 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source Treatment of migraine mainly includes pharmacological approaches aimed at breaking migraine attacks and preventive trea… | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 2026-08-16 19:22:19 | Source |
| Management of refractory chronic migraine using ultrasound-guided pul… Efficacy of Greater Occipital Nerve Radiofrequency for Refractory Migraine Treatment · PMID 30… | Migraine | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Although various oral medications and procedures are applied for managing migraine, their efficacy remains limited. To… | Medicine 2026-08-16 19:22:18 | Source |
| Comparative efficacy, quality of life, safety, and tolerability of at… Rimegepant/BHV3000 · PMID 38410850 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Comparative evaluations of preventive migraine treatments can help inform clinical decision making for managing migrain… | Cephalalgia : an international journal of headache 2026-08-16 19:22:17 | Source |
| Cost per treatment responder analysis of atogepant compared to rimege… Rimegepant/BHV3000 · PMID 39248007 | Migraine | À vérifier | Publication | PubMed | Voir la publication source To estimate the number needed to treat and cost per additional responder for atogepant and rimegepant versus placebo fo… | Headache 2026-08-16 19:22:17 | Source |
| Pharmacological interventions for antipsychotic-induced weight gain i… Topiramate 100 mg · PMID 38878592 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Antipsychotic-induced weight gain (AIWG) is a significant but frequently neglected adverse effect of first- and second-… | General hospital psychiatry 2026-08-16 19:22:16 | Source |
| Propranolol Versus Metoprolol for Treatment of Electrical Storm in Pa… Propranolol 160 mg · PMID 29699616 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Electrical storm (ES), characterized by unrelenting recurrences of ventricular arrhythmias, is observed in approximatel… | Journal of the American College of Cardiology 2026-08-16 19:22:16 | Source |
| Tolerability, safety, and efficacy of atogepant versus topiramate in… Atogepant 60 mg · PMID 42492556 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Oral calcitonin gene-related peptide (CGRP) receptor antagonists such as atogepant have been approved for preventive tr… | The Lancet. Neurology 2026-08-16 19:22:14 | Source |
| Encephalopathy following subcutaneous administration of Brixadi® exte… Fentanyl · PMID 42571226 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Long-acting injectable buprenorphine is one option for the management of opioid use disorder. The United States Food an… | Toxicology reports 2026-08-16 19:22:13 | Source |
Exploration — prudence
Pistes exploratoires 5
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Bavisant BRAVEinMS — Bavisant | Migraine | Remyélinisation · Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Antagonisme du récepteur H3 de l’histamine Bavisant est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migra… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| Tol-MP Tol-MP — tolérance immunitaire spécifique de la myéline | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Microparticules biodégradables chargées en rapamycine et fonctionnalisées… Tol-MP est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migrain… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| SetPoint System SetPoint System — SetPoint Medical | Migraine | Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | re ApplicationsPublicationsCompanyCareersNewsGet startedGet startedNewsThe… SetPoint System est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation immunométabolique de la microglie 4-octyl itaconate et dérivés est étudié dans Sclérose latérale amyotrophique et documente plusieurs axes biologiques po… | Rapprochement Biomedical Watch · Sclérose latérale amy… | Détail |
| N-PPG N-PPG — modulation métabolique cérébrale | Migraine | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation métabolique et mitohormèse N-PPG est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être pertinents pour Migrai… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |