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Périmètre
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8666 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 4050
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Biopsy Procedure NCT06126276 · Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Tar… | Cancer | À vérifier | Phase 2 | RECRUITING | This phase I/II trial studies the side effects and best dose of pidnarulex… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:25 | Détail |
| EBV-T/NK Cohor — Clinical and Biological Cohort Study of EBV-Positive… NCT07727083 · NCT07727083 | Cancer | Ralentissement de la progression | À vérifier | RECRUITING | This is a multicenter, non-interventional, ambidirectional cohort study of… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:25 | Détail |
| EP0057 NCT02769962 · Trial of EP0057, a Nanoparticle Camptothecin With Olaparib in People With Relaps… | Cancer | À vérifier | Phase 1 | TERMINATED | Background: EP0057 (formerly CRLX101) consists of a sugar molecule cyclode… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:25 | Détail |
| Expressive Writing Program Among Young Adults With Blood Cancer NCT07413991 · NCT07413991 | Cancer | Thérapie génique | Non applicable | ACTIVE_NOT_RECRUITING | The goal of this study is to learn more about an expressive writing worksh… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:25 | Détail |
| Romidepsin NCT04447027 · Romidepsin, CC-486 (5-azacitidine), Dexamethasone, and Lenalidomide (RAdR) for R… | Cancer | Traitement symptomatique | Phase 1 | COMPLETED | Background: Mature T-cell malignancies (TCMs) are a rare group of cancers… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:25 | Détail |
| Thyrogen NCT03841617 · The Use of 124-I-PET/CT Whole Body and Lesional Dosimetry in Differentiated Thyr… | Cancer | Thérapie génique | Phase 2 | RECRUITING | Study rationale High risk patients with differentiated thyroid cancer (DTC… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:25 | Détail |
| Biospecimen Collection NCT05722288 · Time-Restricted Eating Versus Nutritional Counseling for the Reduction of Radiat… | Cancer | À vérifier | Phase 2 | ACTIVE_NOT_RECRUITING | This phase III trial compares standard of care hormone therapy plus riboci… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:24 | Détail |
| EUS-DFI in Solid Pancreatic Lesions NCT07763561 · NCT07763561 | Cancer | Thérapie génique | À vérifier | NOT_YET_RECRUITING | This prospective, international, multicenter observational study aims to e… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:24 | Détail |
| Neuropsychological Changes in Patients Receiving Radiation Therapy fo… NCT01445483 · NCT01445483 | Cancer | À vérifier | À vérifier | COMPLETED | Background: * There are no standardized sets of tests to measure changes i… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:24 | Détail |
| Rilvegostomig NCT06692738 · A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for… | Cancer | Ralentissement de la progression | Phase 3 | RECRUITING | DESTINY-Endometrial01 will investigate the efficacy of first-line T-DXd +… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:24 | Détail |
| silevertinib in combination with temozolomide NCT07326566 · Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM… | Cancer | Ralentissement de la progression | Phase 2 | RECRUITING | The purpose of this study is to see if combining silevertinib with temozol… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:24 | Détail |
| Harmonic motion imaging guided focused ultrasound (HMIgFUS) NCT05219695 · Medical Imaging and Focused Ultrasound Treatment for Breast Tumors Using Harmoni… | Cancer | À vérifier | Phase 1 | RECRUITING | This study will investigate Harmonic Motion Imaging guided Focused Ultraso… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:23 | Détail |
| Liposomal Amphotericin B NCT07763054 · Low-dose Liposomal Amphotericin B for Antifungal Prophylaxis in Prolonged Neutro… | Cancer | À vérifier | À vérifier | RECRUITING | This is a single-center, single-arm, observational clinical study evaluati… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:23 | Détail |
| Lorlatinib NCT06007937 · A Study of Lorlatinib in Combination With Ramucirumab in People With Lung Cancer | Cancer | À vérifier | Phase 1 | ACTIVE_NOT_RECRUITING | This study will test the safety of the combination of ramucirumab and lorl… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:23 | Détail |
| M1774 NCT04170153 · Tuvusertib (M1774) in Participants With Metastatic or Locally Advanced Unresecta… | Cancer | À vérifier | Phase 1 | ACTIVE_NOT_RECRUITING | This is an open-label, Phase I, first-in-human (FIH) multicenter, clinical… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:23 | Détail |
| Opevesostat NCT06136650 · A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Age… | Cancer | Ralentissement de la progression · Thérapie génique | Phase 3 | RECRUITING | The purpose of this study is to assess the efficacy and safety of opevesos… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:23 | Détail |
| Risk Communication Within Mexican-American Families NCT00469339 · NCT00469339 | Cancer | À vérifier | À vérifier | COMPLETED | This study will examine what methods work best for encouraging Mexican-Ame… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:23 | Détail |
| 18F-DCFPyL NCT03181867 · 18F-DCFPyL PET/CT in High Risk and Recurrent Prostate Cancer | Cancer | À vérifier | Phase 2 | ACTIVE_NOT_RECRUITING | Background: Prostate cancer is the second leading cause of cancer deaths i… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:22 | Détail |
| aldesleukin NCT06904066 · Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Partic… | Cancer | Immunomodulation · Thérapie génique | Phase 1 | RECRUITING | Background: Blood cancers (such as leukemias) can be hard to treat, especi… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:22 | Détail |
| Anakinra (Kineret®) NCT06703216 · PACER — Pre-emptive Anakinra for Cytokine Event Reduction | Cancer | Ralentissement de la progression · Thérapie cellulaire | Phase 1 | WITHDRAWN | Objectives: The primary objective of this study will be to evaluate the im… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:22 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4595
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Effects of testosterone-augmented multimodal exercise intervention in… Whole-body Electrical Muscle Stimulation Exercise · PMID 41988780 | Myasthénie | À vérifier | Publication | PubMed | Voir la publication source Spinal cord injury (SCI) leads to profound muscle atrophy, aerobic deconditioning, and metabolic dysfunction. Exercise-… | The Journal of clinical endocrinology and metabolism 2026-09-20 04:37:05 | Source |
| Feasibility and acceptability of whole-body electromyostimulation in… Whole-body Electrical Muscle Stimulation Exercise · PMID 42464389 | Myasthénie | À vérifier | Publication | PubMed | Voir la publication source Evidence on the effectiveness of electromyostimulation (EMS) has been reported in pulmonary rehabilitation, but the ben… | Pilot and feasibility studies 2026-09-20 04:37:05 | Source |
| Vestibular contributions adapt to the balance strategies adopted duri… Whole-body Electrical Muscle Stimulation Exercise · PMID 42616645 | Myasthénie | À vérifier | Publication | PubMed | Voir la publication source Vestibular contributions during walking are not uniform, but vary with gait phase, muscle group, and balance demands. M… | Journal of neurophysiology 2026-09-20 04:37:05 | Source |
| Clinical efficacy of abdominal moxibustion at the Zhongji (CV3) in co… Yangyin Roujin Decoction · PMID 42015783 | Myopathies | Neuroprotection · Traitement symptomatique | Publication | PubMed | Voir la publication source To investigate the clinical effect of abdominal moxibustion at the Zhongji (CV3) combined with Yiqi Tonglin Yangyin dec… | Journal of traditional Chinese medicine = Chung i tsa… 2026-09-20 04:37:03 | Source |
| Yiqi Huoxue Yangyin Decoction Ameliorates Diabetic Nephropathy by Tar… Yangyin Roujin Decoction · PMID 42713045 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source This study aimed to investigate the protective effects and underlying mechanisms of Yiqi Huoxue Yangyin Decoction (YHY)… | Diabetes, metabolic syndrome and obesity : targets and… 2026-09-20 04:37:03 | Source |
| Yiqi Huoxue Yangyin Decoction attenuates diabetic nephropathy in mice… Yangyin Roujin Decoction · PMID 42016924 | Myopathies | Thérapie génique | Publication | PubMed | Voir la publication source Diabetic nephropathy (DN) is a major complication of diabetes with limited therapeutic options. Yiqi Huoxue Yangyin Dec… | Frontiers in pharmacology 2026-09-20 04:37:03 | Source |
| Barcoded oligonucleotide system (BOLT) for targeted organ delivery. Immunotherapy · PMID 42733790 | Cancer | À vérifier | Publication | PubMed | Voir la publication source The therapeutic potential of oligonucleotides (oligos) is limited by insufficient delivery to extrahepatic tissues. In… | Bioactive materials 2026-09-20 04:36:56 | Source |
| Dual metabolic checkpoint blockade a 3D-Printed metalloplatform remod… Immunotherapy · PMID 42724565 | Cancer | Immunomodulation | Publication | PubMed | Voir la publication source The immunosuppressive tumor microenvironment limits the efficacy of therapies that target metabolism. Here we show a st… | Bioactive materials 2026-09-20 04:36:56 | Source |
| Oligosaccharide adjuvant-deferred antigen endocytosis promotes cross-… Immunotherapy · PMID 42751513 | Cancer | Immunomodulation · Thérapie génique | Publication | PubMed | Voir la publication source Antigen cross-presentation by dendritic cells (DCs) is essential for inducing cytotoxic immune responses, which are cru… | Bioactive materials 2026-09-20 04:36:56 | Source |
| Feasibility and safety of early discharge after robot-assisted uro-on… Digital care pathway for hypertension · PMID 42671715 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source Early discharge after robot-assisted uro-oncologic surgery remains limited by concerns regarding patient safety and the… | Journal of robotic surgery 2026-09-20 04:36:49 | Source |
| HomeSafe: Postpartum Hypertensive Care Enabled by Electronic Health R… Digital care pathway for hypertension · PMID 41707683 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source The objective is to present stepwise refinements to , an Epic-tethered, population-health-coordinated postpartum pathwa… | American journal of perinatology 2026-09-20 04:36:49 | Source |
| Nutraceutical and functional food: efficacy against metabolic disorde… Digital care pathway for hypertension · PMID 42603698 | Hypertension artérielle | Neuroprotection · Immunomodulation | Publication | PubMed | Voir la publication source The growing global emphasis on health consciousness has significantly increased demand for traditional and complementar… | Journal of advanced research 2026-09-20 04:36:49 | Source |
| Community-engaged design of a virtual diabetes prevention program int… Asynchronous communication with nurse · PMID 42288862 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source The Diabetes Prevention Program (DPP) is an evidence-based approach to prevent Type 2 Diabetes (T2D), the leading cause… | BMC health services research 2026-09-20 04:36:48 | Source |
| Evolving Lung Cancer Navigator Practice Through Targeted Professional… Asynchronous communication with nurse · PMID 42463006 | Cancer | À vérifier | Publication | PubMed | Voir la publication source Lung cancer remains the leading cause of cancer deaths worldwide, and it has persistent disparities in detection, treat… | Chest 2026-09-20 04:36:48 | Source |
| Mass casualty training for prehospital and emergency providers in Kig… Asynchronous communication with nurse · PMID 42751142 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source A mass casualty incident (MCI) occurs when the number of patients exceeds available healthcare resources, placing signi… | African journal of emergency medicine : Revue africain… 2026-09-20 04:36:48 | Source |
| Innovating a Teach-Back Model for Community Health Workers Led Health… Health Literacy Project · PMID 40194526 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source From 2021 to 2023, the City of Albuquerque, the University of New Mexico (UNM) Office for Community Health, the UNM Hos… | Health literacy research and practice 2026-09-20 04:36:34 | Source |
| Carotid intima-media thickness may be an early biomarker for cardiova… Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy · PMID 41026111 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source To assess early signs of atherosclerosis following long-term treatment with the ketogenic diet therapy due to concerns… | Epilepsia open 2026-09-20 04:36:33 | Source |
| Impact of low-carbohydrate diet on health status: an umbrella review. Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy · PMID 39385794 | Cancer | À vérifier | Publication | PubMed | Voir la publication source The prevalence of diet-related non-communicable diseases has increased. A low-carbohydrate diet (LCDs) is one of the mo… | Frontiers in nutrition 2026-09-20 04:36:33 | Source |
| The effect of anti-seizure medications on lipid values in adults with… Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy · PMID 37244221 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source Certain anti-seizure medications (ASMs) adversely impact lipid values. Here, we explored the impact of ASMs on lipid va… | Epilepsy & behavior : E&B 2026-09-20 04:36:33 | Source |
| Possible role of locus coeruleus neuronal loss in age-related memory… The Role of the Locus Coeruleus in Age-related Distractibility · PMID 37694113 | Maladie d’Alzheimer | Immunomodulation | Publication | PubMed | Voir la publication source Aging is associated with a decline in cognitive abilities, including memory and attention. It is generally accepted tha… | Frontiers in neuroscience 2026-09-20 04:36:30 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||