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Périmètre
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8666 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 4050
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| INS1202 NCT07290062 · ARMOR — A Study to Investigate the Safety and Pharmacodynamics of a Single Intra… | Sclérose latérale amyotrophique | À vérifier | Phase 1 | RECRUITING | Description non affichée : incohérence de maladie détectée. Consultez l’es… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:40 | Détail |
| Intravenous and Intranasal BMSC NCT02795052 · NEST — Neurologic Stem Cell Treatment Study | Sclérose latérale amyotrophique | Thérapie cellulaire | Non applicable | RECRUITING | This is a human clinical study involving the isolation of autologous bone… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:40 | Détail |
| Lumbar Puncture NCT07213440 · PremodiALS — Identification of Early Markers for ALS | Sclérose latérale amyotrophique | Traitement symptomatique | Non applicable | RECRUITING | Background: Mature T-cell malignancies (TCMs) are a rare group of cancers… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:40 | Détail |
| LY4256984 NCT07571200 · A Master Protocol (OLMP): A Study of LY4256984 in Participants With Amyotrophic… | Sclérose latérale amyotrophique | À vérifier | Phase 1 | RECRUITING | Description non affichée : incohérence de maladie détectée. Consultez l’es… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:40 | Détail |
| MT-1186 NCT04254913 · Clinical Pharmacology Study of Oral Edaravone in Amyotrophic Lateral Sclerosis P… | Sclérose latérale amyotrophique | À vérifier | Phase 1 | COMPLETED | Description non affichée : incohérence de maladie détectée. Consultez l’es… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:40 | Détail |
| MT-1186 NCT04176224 · Clinical Pharmacology Study of Oral Edaravone in Patients With Amyotrophic Later… | Sclérose latérale amyotrophique | À vérifier | Phase 1 | COMPLETED | Description non affichée : incohérence de maladie détectée. Consultez l’es… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:40 | Détail |
| Next Generation Dome Helmet Focused Ultrasound NCT07193953 · ALSFUS003 — Intravenous Immunoglobulin (IVIG) and Blood-Brain Barrier Disruption… | Sclérose latérale amyotrophique | À vérifier | Phase 1 | ACTIVE_NOT_RECRUITING | Description non affichée : incohérence de maladie détectée. Consultez l’es… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:40 | Détail |
| Non-invasive ventilation NCT07071935 · A Clinical Trial of Early Ventilation in Amyotrophic Lateral Sclerosis (EVENT AL… | Sclérose latérale amyotrophique | Traitement symptomatique | Phase 2 | RECRUITING | Description non affichée : incohérence de maladie détectée. Consultez l’es… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:40 | Détail |
| VHB937 NCT06643481 · ASTRALS — A Clinical Trial to Learn About the Effects of VHB937 in People With A… | Sclérose latérale amyotrophique | Traitement symptomatique | Phase 2 | ACTIVE_NOT_RECRUITING | Description non affichée : incohérence de maladie détectée. Consultez l’es… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:40 | Détail |
| CD19/BCMA-targeted CAR-T cells NCT07337785 · CD19/BCMA-Targeted UCAR-T for Patients With Neurological Autoimmune Diseases | Myasthénie | Immunomodulation · Thérapie cellulaire | Phase 1 | RECRUITING | This single-arm, open-label investigator-initiated trial (IIT) evaluates t… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:38 | Détail |
| Depressive Tendency and Counseling Outcomes in Thymoma-Associated MG NCT07649187 · NCT07649187 | Myasthénie | À vérifier | Non applicable | COMPLETED | This study aimed to examine whether baseline depressive tendency independe… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:38 | Détail |
| Efgartigimod IV NCT04980495 · ADAPT NXT — An Open-label Study to Investigate the Clinical Efficacy of Differen… | Myasthénie | À vérifier | Phase 3 | COMPLETED | The purpose of this trial is to investigate the PK, PD, safety, and activi… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:38 | Détail |
| EXPLORE-MG2 — Exploring Outcomes and Characteristics of Myasthenia Gr… NCT06002945 · NCT06002945 | Myasthénie | Thérapie génique | À vérifier | COMPLETED | The goal of this prospective observational study is to create a network re… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:38 | Détail |
| Inebilizumab NCT04524273 · MINT — Myasthenia Gravis Inebilizumab Trial | Myasthénie | À vérifier | Phase 3 | ACTIVE_NOT_RECRUITING | The main objective is to assess the safety and tolerability of inebilizuma… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:38 | Détail |
| LVIVO-TaVec400 product NCT07583030 · A Clinical Study to Evaluate LVIVO-TaVec400 for the Treatment of Relapsed/Refrac… | Myasthénie | À vérifier | Phase 1 | NOT_YET_RECRUITING | This is a prospective, single-arm, open-label dose-escalation clinical stu… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:38 | Détail |
| MG Cohort — A Study in Patients With Myasthenia Gravis in China NCT06700616 · NCT06700616 | Myasthénie | À vérifier | À vérifier | ACTIVE_NOT_RECRUITING | This study is a multi-center, prospective cohort study designed to charact… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:38 | Détail |
| MTM-H-001 Injection NCT07593911 · ArchAid-002 — A Study to Evaluate MTM-H-001 Injection in Adult Patients With B-C… | Myasthénie | À vérifier | Non applicable | NOT_YET_RECRUITING | This is an investigator-initiated, open-label, single-arm, dose-escalation… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:38 | Détail |
| POEMA — A Study to Evaluate the Impact of Efgartigimod on Overall Dis… NCT07595653 · NCT07595653 | Myasthénie | À vérifier | À vérifier | RECRUITING | This study aims to generate real world evidence (RWE) from Italian clinica… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:38 | Détail |
| REAL MG PRO — Monitor the Evolution of Myasthenia Gravis Symptoms in… NCT07570589 · REAL MG PRO — Monitor the Evolution of Myasthenia Gravis Symptoms in Real-life i… | Myasthénie | Traitement symptomatique | À vérifier | RECRUITING | Generalized Myasthenia Gravis (gMG) is a rare autoimmune disease (a diseas… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:38 | Détail |
| rozanolixizumab NCT07246564 · Phase 4 Study Evaluating Efficacy and Safety of Rozanolixizumab in Adult Chinese… | Myasthénie | À vérifier | Phase 4 | RECRUITING | The purpose of the study is to assess the safety and tolerability of subcu… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:38 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4595
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Effects of testosterone-augmented multimodal exercise intervention in… Whole-body Electrical Muscle Stimulation Exercise · PMID 41988780 | Myasthénie | À vérifier | Publication | PubMed | Voir la publication source Spinal cord injury (SCI) leads to profound muscle atrophy, aerobic deconditioning, and metabolic dysfunction. Exercise-… | The Journal of clinical endocrinology and metabolism 2026-09-20 04:37:05 | Source |
| Feasibility and acceptability of whole-body electromyostimulation in… Whole-body Electrical Muscle Stimulation Exercise · PMID 42464389 | Myasthénie | À vérifier | Publication | PubMed | Voir la publication source Evidence on the effectiveness of electromyostimulation (EMS) has been reported in pulmonary rehabilitation, but the ben… | Pilot and feasibility studies 2026-09-20 04:37:05 | Source |
| Vestibular contributions adapt to the balance strategies adopted duri… Whole-body Electrical Muscle Stimulation Exercise · PMID 42616645 | Myasthénie | À vérifier | Publication | PubMed | Voir la publication source Vestibular contributions during walking are not uniform, but vary with gait phase, muscle group, and balance demands. M… | Journal of neurophysiology 2026-09-20 04:37:05 | Source |
| Clinical efficacy of abdominal moxibustion at the Zhongji (CV3) in co… Yangyin Roujin Decoction · PMID 42015783 | Myopathies | Neuroprotection · Traitement symptomatique | Publication | PubMed | Voir la publication source To investigate the clinical effect of abdominal moxibustion at the Zhongji (CV3) combined with Yiqi Tonglin Yangyin dec… | Journal of traditional Chinese medicine = Chung i tsa… 2026-09-20 04:37:03 | Source |
| Yiqi Huoxue Yangyin Decoction Ameliorates Diabetic Nephropathy by Tar… Yangyin Roujin Decoction · PMID 42713045 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source This study aimed to investigate the protective effects and underlying mechanisms of Yiqi Huoxue Yangyin Decoction (YHY)… | Diabetes, metabolic syndrome and obesity : targets and… 2026-09-20 04:37:03 | Source |
| Yiqi Huoxue Yangyin Decoction attenuates diabetic nephropathy in mice… Yangyin Roujin Decoction · PMID 42016924 | Myopathies | Thérapie génique | Publication | PubMed | Voir la publication source Diabetic nephropathy (DN) is a major complication of diabetes with limited therapeutic options. Yiqi Huoxue Yangyin Dec… | Frontiers in pharmacology 2026-09-20 04:37:03 | Source |
| Barcoded oligonucleotide system (BOLT) for targeted organ delivery. Immunotherapy · PMID 42733790 | Cancer | À vérifier | Publication | PubMed | Voir la publication source The therapeutic potential of oligonucleotides (oligos) is limited by insufficient delivery to extrahepatic tissues. In… | Bioactive materials 2026-09-20 04:36:56 | Source |
| Dual metabolic checkpoint blockade a 3D-Printed metalloplatform remod… Immunotherapy · PMID 42724565 | Cancer | Immunomodulation | Publication | PubMed | Voir la publication source The immunosuppressive tumor microenvironment limits the efficacy of therapies that target metabolism. Here we show a st… | Bioactive materials 2026-09-20 04:36:56 | Source |
| Oligosaccharide adjuvant-deferred antigen endocytosis promotes cross-… Immunotherapy · PMID 42751513 | Cancer | Immunomodulation · Thérapie génique | Publication | PubMed | Voir la publication source Antigen cross-presentation by dendritic cells (DCs) is essential for inducing cytotoxic immune responses, which are cru… | Bioactive materials 2026-09-20 04:36:56 | Source |
| Feasibility and safety of early discharge after robot-assisted uro-on… Digital care pathway for hypertension · PMID 42671715 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source Early discharge after robot-assisted uro-oncologic surgery remains limited by concerns regarding patient safety and the… | Journal of robotic surgery 2026-09-20 04:36:49 | Source |
| HomeSafe: Postpartum Hypertensive Care Enabled by Electronic Health R… Digital care pathway for hypertension · PMID 41707683 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source The objective is to present stepwise refinements to , an Epic-tethered, population-health-coordinated postpartum pathwa… | American journal of perinatology 2026-09-20 04:36:49 | Source |
| Nutraceutical and functional food: efficacy against metabolic disorde… Digital care pathway for hypertension · PMID 42603698 | Hypertension artérielle | Neuroprotection · Immunomodulation | Publication | PubMed | Voir la publication source The growing global emphasis on health consciousness has significantly increased demand for traditional and complementar… | Journal of advanced research 2026-09-20 04:36:49 | Source |
| Community-engaged design of a virtual diabetes prevention program int… Asynchronous communication with nurse · PMID 42288862 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source The Diabetes Prevention Program (DPP) is an evidence-based approach to prevent Type 2 Diabetes (T2D), the leading cause… | BMC health services research 2026-09-20 04:36:48 | Source |
| Evolving Lung Cancer Navigator Practice Through Targeted Professional… Asynchronous communication with nurse · PMID 42463006 | Cancer | À vérifier | Publication | PubMed | Voir la publication source Lung cancer remains the leading cause of cancer deaths worldwide, and it has persistent disparities in detection, treat… | Chest 2026-09-20 04:36:48 | Source |
| Mass casualty training for prehospital and emergency providers in Kig… Asynchronous communication with nurse · PMID 42751142 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source A mass casualty incident (MCI) occurs when the number of patients exceeds available healthcare resources, placing signi… | African journal of emergency medicine : Revue africain… 2026-09-20 04:36:48 | Source |
| Innovating a Teach-Back Model for Community Health Workers Led Health… Health Literacy Project · PMID 40194526 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source From 2021 to 2023, the City of Albuquerque, the University of New Mexico (UNM) Office for Community Health, the UNM Hos… | Health literacy research and practice 2026-09-20 04:36:34 | Source |
| Carotid intima-media thickness may be an early biomarker for cardiova… Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy · PMID 41026111 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source To assess early signs of atherosclerosis following long-term treatment with the ketogenic diet therapy due to concerns… | Epilepsia open 2026-09-20 04:36:33 | Source |
| Impact of low-carbohydrate diet on health status: an umbrella review. Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy · PMID 39385794 | Cancer | À vérifier | Publication | PubMed | Voir la publication source The prevalence of diet-related non-communicable diseases has increased. A low-carbohydrate diet (LCDs) is one of the mo… | Frontiers in nutrition 2026-09-20 04:36:33 | Source |
| The effect of anti-seizure medications on lipid values in adults with… Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy · PMID 37244221 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source Certain anti-seizure medications (ASMs) adversely impact lipid values. Here, we explored the impact of ASMs on lipid va… | Epilepsy & behavior : E&B 2026-09-20 04:36:33 | Source |
| Possible role of locus coeruleus neuronal loss in age-related memory… The Role of the Locus Coeruleus in Age-related Distractibility · PMID 37694113 | Maladie d’Alzheimer | Immunomodulation | Publication | PubMed | Voir la publication source Aging is associated with a decline in cognitive abilities, including memory and attention. It is generally accepted tha… | Frontiers in neuroscience 2026-09-20 04:36:30 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||