Vue transversale de la maladie
Myopathies
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
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1012 résultats correspondants
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dans le périmètre Myopathies
Niveau clinique
Études et traitements 421
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| AB-1003 dose level 1 NCT05230459 · A Study to Evaluate the Safety of AB-1003 (Previously LION-101) in Subjects With… | Myopathies | À vérifier | Phase 1/2 | ACTIVE_NOT_RECRUITING | The purpose of this study is to evaluate the safety and tolerability of a… À vérifier | ClinicalTrials.gov 2026-09-01 09:22:28 | Détail |
| Alternate-day prednisolone NCT07787689 · Intermittent vs Alternate Daily Regimen of Prednisolone in Ambulatory Boys With… | Myopathies | Thérapie génique | Non applicable | NOT_YET_RECRUITING | The alternate-day regimen is hypothesized to reduce hypothalamic-pituitary… À vérifier | ClinicalTrials.gov 2026-09-01 09:22:28 | Détail |
| ELEVIDYS NCT07542314 · ENHANCE — Study to Evaluate the Safety and Effectiveness of ELEVIDYS in Particip… | Myopathies | À vérifier | Phase 4 | NOT_YET_RECRUITING | The primary objective of this study is to evaluate acute liver injury (ALI… À vérifier | ClinicalTrials.gov 2026-09-01 09:22:28 | Détail |
| Evaluating VM100 Nutritional Supplement for Improving Quality of Life… NCT07766980 · NCT07766980 | Myopathies | Traitement symptomatique | Non applicable | RECRUITING | This pilot study will investigate the potential efficacy of VM100, a nutri… À vérifier | ClinicalTrials.gov 2026-09-01 09:22:28 | Détail |
| force gravity stimulation NCT07780435 · Whole-body Vibration Versus Gravity Force Stimulation on Postural Stability in C… | Myopathies | À vérifier | Non applicable | COMPLETED | this study aimed to mention Does whole-body vibration training or gravity-… À vérifier | ClinicalTrials.gov 2026-09-01 09:22:28 | Détail |
| International GNE Myopathy Patient Registry NCT04009226 · NCT04009226 | Myopathies | Ralentissement de la progression | À vérifier | COMPLETED | GNE myopathy, an ultra-rare disease, is a severe progressive myopathy that… À vérifier | ClinicalTrials.gov 2026-09-01 09:22:28 | Détail |
| Investigational Use of Neuromuscular Ultrasound NCT05237973 · NCT05237973 | Myopathies | Traitement symptomatique · Thérapie génique | À vérifier | RECRUITING | Background: Current techniques used to measure the health and function of… À vérifier | ClinicalTrials.gov 2026-09-01 09:22:28 | Détail |
| Observation Study in Patients Age 0-5 Years With LAMA2-related Congen… NCT06503367 · NCT06503367 | Myopathies | Thérapie génique | À vérifier | RECRUITING | The goal of this observational study is to understand how young children w… À vérifier | ClinicalTrials.gov 2026-09-01 09:22:28 | Détail |
| TAS-205 [Ambulatory Cohort] [Non-ambulatory Cohort] NCT04587908 · A Phase 3 Study of TAS-205 in Patients With Duchenne Muscular Dystrophy（REACH-DM… | Myopathies | À vérifier | Phase 3 | COMPLETED | The purpose of this study is to evaluate the efficacy and safety of TAS-20… À vérifier | ClinicalTrials.gov 2026-09-01 09:22:28 | Détail |
| The Baby Duchenne Study: Characterizing Developmental and Clinical Ou… NCT07092540 · NCT07092540 | Myopathies | À vérifier | À vérifier | RECRUITING | The aim of the BABY DUCHENNE study is to evaluate the natural history and… À vérifier | ClinicalTrials.gov 2026-09-01 09:22:28 | Détail |
| The United Kingdom Facioscapulohumeral Muscular Dystrophy Patient Reg… NCT04001582 · NCT04001582 | Myopathies | À vérifier | À vérifier | RECRUITING | Facioscapulohumeral Dystrophy (FSHD) is the third most common form of neur… À vérifier | ClinicalTrials.gov 2026-09-01 09:22:28 | Détail |
| VX-670 NCT06185764 · Galileo — A Phase 1/2 Study of VX-670 in Adult Participants With Myotonic Dystro… | Myopathies | À vérifier | Phase 1/2 | ACTIVE_NOT_RECRUITING | The purpose of the study is to evaluate the long-term safety and tolerabil… À vérifier | ClinicalTrials.gov 2026-09-01 09:22:28 | Détail |
| Active full-body stimulation NCT07132775 · Evaluation of the Safety and Efficacy of a Full-Body Electrostimulation Garment… | Myopathies | Traitement symptomatique | Non applicable | RECRUITING | The purpose of this study is to to explore the safety and efficacy of the… À vérifier | ClinicalTrials.gov 2026-09-01 09:22:27 | Détail |
| A Natural History Study of Patients With GNE Myopathy and GNE-Related… NCT01417533 · NCT01417533 | Myopathies | Traitement symptomatique · Thérapie génique | À vérifier | COMPLETED | Background: \- GNE Myopathy is a disease that causes walking difficulties… À vérifier | ClinicalTrials.gov 2026-09-01 09:22:27 | Détail |
| Antidepressant NCT04747314 · TNA-LBP — Treating Negative Affect in Low Back Pain Patients | Myopathies | Traitement symptomatique | Phase 2 | COMPLETED | This study will examine how the use of antidepressant, physical therapy, a… À vérifier | ClinicalTrials.gov 2026-09-01 09:22:27 | Détail |
| Deramiocel (CAP-1002) NCT05126758 · HOPE-3 — A Study of Deramiocel (CAP-1002) in Ambulatory and Non-Ambulatory Patie… | Myopathies | Thérapie cellulaire | Phase 3 | ACTIVE_NOT_RECRUITING | HOPE-3 is a two cohort, Phase 3, multi-center, randomized, double-blind, p… À vérifier | ClinicalTrials.gov 2026-09-01 09:22:27 | Détail |
| FOPal — A Study to Document and to Further Describe Long-term Safety… NCT06089616 · NCT06089616 | Myopathies | Traitement symptomatique | À vérifier | RECRUITING | The participants in this registry study will have fibrodysplasia ossifican… À vérifier | ClinicalTrials.gov 2026-09-01 09:22:27 | Détail |
| Metformin NCT00720161 · Metformin in Children With Motor Deficit | Myopathies | À vérifier | Non applicable | COMPLETED | The goal of this clinical trial is to Evaluating Metformin Efficacy and Sa… À vérifier | ClinicalTrials.gov 2026-09-01 09:22:27 | Détail |
| MOTIVATE_IIR — MOTIVATE to Improve Outcomes for Older Veterans With M… NCT05220202 · NCT05220202 | Myopathies | Traitement symptomatique | Non applicable | COMPLETED | The proposed study seeks to evaluate effectiveness, implementation process… À vérifier | ClinicalTrials.gov 2026-09-01 09:22:27 | Détail |
| Nerandomilast NCT07789015 · VERANDA™-IIM — A Study to Understand How Nerandomilast Works in People With Acti… | Myopathies | Immunomodulation · Traitement symptomatique | Phase 3 | NOT_YET_RECRUITING | This study is open to adults aged 18 and older who have a condition known… À vérifier | ClinicalTrials.gov 2026-09-01 09:22:27 | Détail |
Découverte scientifique
Recherches et trouvailles 0
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune trouvaille ne correspond aux filtres. | |||||||
Bibliographie
Publications 585
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Transcutaneous forceps-assisted en-bloc removal of a large intra-arti… Operative arthroscopy · PMID 42350181 | Myopathies | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Large intra-articular loose bodies of the temporomandibular joint can limit operative arthroscopy when their size preve… | International journal of oral and maxillofacial surgery 2026-08-13 15:04:07 | Source |
| Arthroscopy-assisted inferior compartment arthrocentesis of the tempo… Arthroscopic lysis and lavage · PMID 42530686 | Myopathies | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Arthroscopic lysis and lavage of the temporomandibular joint (TMJ) is an established treatment for internal derangement… | Oral and maxillofacial surgery 2026-08-13 15:04:06 | Source |
| What are the outcomes of jaw function and pain reduction with advance… Arthroscopic lysis and lavage · PMID 41622095 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source When temporomandibular joint (TMJ) lysis and lavage procedures fail to treat intraarticular pain and dysfunction (IPD),… | International journal of oral and maxillofacial surgery 2026-08-13 15:04:06 | Source |
| Depressive Symptoms Are Associated With Lower Patient Expectations fo… Patient-Centered Assessment of Symptoms and Outcomes · PMID 42585646 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source Patients' expectations for recovery after cardiac intensive care unit (CICU) admission may influence their engagement i… | The Journal of cardiovascular nursing 2026-08-13 15:04:05 | Source |
| Palliative care among cancer patients in Georgia: System-level gaps i… Patient-Centered Assessment of Symptoms and Outcomes · PMID 42582999 | Myopathies | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Palliative care aims to improve health-related quality of life (HRQoL) through holistic, patient-centered approaches. I… | Journal of public health research 2026-08-13 15:04:05 | Source |
| Compact Arterial Monitoring Device Use in Resuscitative Endovascular… The Impact of Intra-Abdominal Pressure on Mortality and Morbidity in Patients Undergoing Open-… | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Introduction Hemorrhage is the leading cause of preventable death in trauma in both the military and civilian settings… | Cureus 2026-08-13 15:04:04 | Source |
| Molecular hydrogen as a treatment for ME/CFS: a mini-review of clinic… ME/CFS — Controlled Trial of Hydrogen Water as a Treatment for Myalgic Encephalomyelitis/Chron… | Myopathies | Remyélinisation indirecte / réparation · Neuroprotection · Immunomodulation · T… | Publication | PubMed | Voir la publication source Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating multisystem illness characterized by prof… | Frontiers in medicine 2026-08-13 15:04:03 | Source |
| ACDF Impact on Aerodigestive Function and Obstructive Sleep Apnea: A… Discectomy · PMID 42587397 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Anterior cervical discectomy and fusion (ACDF) treats cervical disc herniation, cervical spondylosis, and spinal stenos… | The Laryngoscope 2026-08-13 15:04:02 | Source |
| Equivalent Clinical Outcomes but Divergent Biological Adaptation Afte… Discectomy · PMID 42590218 | Myopathies | Ralentissement de la progression · Traitement symptomatique | Publication | PubMed | Voir la publication source Anterior cervical discectomy and fusion (ACDF) and cervical disc arthroplasty (CDA) can produce comparable short-term c… | Journal of clinical medicine 2026-08-13 15:04:02 | Source |
| Gentamicin pre-soaking of hamstring autografts decreases infection ra… Arthroscopy & saline irrigation alone · PMID 33537678 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Graft infection following anterior cruciate ligament reconstruction (ACLR) may lead to septic arthritis requiring multi… | Bone & joint open 2026-08-13 15:04:02 | Source |
| The effect of tranexamic acid and epinephrine on visual clarity durin… Arthroscopy & saline irrigation alone · PMID 38395349 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source Visual clarity in arthroscopic rotator cuff repair is essential to reduce the operative time and for efficiency of repa… | Orthopaedics & traumatology, surgery & research : OTSR 2026-08-13 15:04:02 | Source |
| Acute physiological responses to combined blood flow restriction and… Sham Low Level Laser Therapy · PMID 32318813 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source Blood flow restriction (BFR) is an innovation in fitness to train muscles with low loads at low oxygen levels. Low-leve… | European journal of applied physiology 2026-08-13 15:04:00 | Source |
| Photobiomodulation in the management of oral mucositis for adult head… Sham Low Level Laser Therapy · PMID 36484364 | Myopathies | Immunomodulation · Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Oral mucositis is a debilitating and painful complication of head and neck cancer irradiation that is characterised by… | Health technology assessment (Winchester, England) 2026-08-13 15:04:00 | Source |
| Bibliometric analysis in the field of photobiomodulation in the last… Low Level Laser Therapy · PMID 42586290 | Myopathies | Thérapie génique | Publication | PubMed | Voir la publication source Photobiomodulation (PBM) has evolved into a vibrant interdisciplinary field. Despite rapid research expansion, a compre… | Photodiagnosis and photodynamic therapy 2026-08-13 15:03:59 | Source |
| Efficacy of 810 nm low-level laser therapy on muscle regeneration aft… Low Level Laser Therapy · PMID 42579184 | Myopathies | Remyélinisation indirecte / réparation · Immunomodulation | Publication | PubMed | Voir la publication source Skeletal muscle tissue has considerable regenerative capacity following injury; yet, this process may be gradual and co… | Lasers in medical science 2026-08-13 15:03:59 | Source |
| Bilateral transcutaneous auricular nerve stimulation promotes motor f… Combined vagus nerve stimulation and medical treatment · PMID 42564705 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Vagus nerve stimulation (VNS) has emerged as a promising adjunctive approach for stroke rehabilitation. However, curren… | Therapeutic advances in neurological disorders 2026-08-13 15:03:57 | Source |
| Swallowing therapy for dysphagia in acute and subacute stroke. Combined vagus nerve stimulation and medical treatment · PMID 42573047 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Post-stroke dysphagia ((PSD) impaired swallowing following stroke), increases risk of death, yet the effects of potenti… | The Cochrane database of systematic reviews 2026-08-13 15:03:57 | Source |
| Clinical Practice Recommendations for Non-Dermatologists on the Diagn… Medical treatment · PMID 42590188 | Myopathies | Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Generalized pustular psoriasis (GPP) is a rare, potentially life-threatening, chronic cutaneous inflammatory disease ch… | Journal of clinical medicine 2026-08-13 15:03:56 | Source |
| Mechanisms Underlying the Benefits of Coffee in Postoperative Ileus. Medical treatment · PMID 42588126 | Myopathies | Immunomodulation | Publication | PubMed | Voir la publication source Postoperative ileus (POI) is a motility dysfunction associated with inflammation in the gastrointestinal (GI) tract aft… | Nutrients 2026-08-13 15:03:56 | Source |
| Prednisone, not vamorolone, suppresses novel serum bone and cartilage… Vamorolone · PMID 42547787 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Corticosteroids are among the most highly prescribed drugs. Chronic treatment with corticosteroids causes osteopenia, a… | Scientific reports 2026-08-13 15:03:55 | Source |
Exploration — prudence
Pistes exploratoires 6
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| N-PPG N-PPG — modulation métabolique cérébrale | Myopathies | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation métabolique et mitohormèse N-PPG est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être pertinents pour Myopat… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |
| Vecteur Ple389 (ADORA2A) MiniPromoter Ple389 — ciblage striatal | Myopathies | Thérapie génique | Hypothèse exploratoire | Rapprochement automatique non validé | Expression génique ciblée dans les neurones striataux Vecteur Ple389 (ADORA2A) est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être per… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |
| α-Amyrin α-Amyrin — protection mitochondriale | Myopathies | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Protection mitochondriale et modulation de la pathologie Tau α-Amyrin est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pour Myopa… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Myopathies | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation immunométabolique de la microglie 4-octyl itaconate et dérivés est étudié dans Sclérose latérale amyotrophique et documente plusieurs axes biologiques po… | Rapprochement Biomedical Watch · Sclérose latérale amy… | Détail |
| Thonningianin A Thonningianin A — neuroprotection anti-amyloïde | Myopathies | Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation du stress oxydatif et des protéines associées à Alzheimer Thonningianin A est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |
| Vutiglabridin Vutiglabridin — autophagie et PON2 | Myopathies | Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Activation de PON2 et stimulation de l’autophagie Vutiglabridin est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pour… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |