Vue transversale de la maladie
Myopathies
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
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1012 résultats correspondants
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dans le périmètre Myopathies
Niveau clinique
Études et traitements 421
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Characterization of the Natural History of LAMA2-RD and Identificatio… NCT07125040 · NCT07125040 | Myopathies | Thérapie génique | À vérifier | RECRUITING | The goal of this observational study is to learn about the natural history… À vérifier | ClinicalTrials.gov 2026-07-29 15:50:58 | Détail |
| Focal Muscular Vibration using the EVM EVO medical device (Endomedica… NCT05464160 · Focal Muscular Vibration in Patients with Severe Acquired Brain Injury | Myopathies | Ralentissement de la progression · Traitement symptomatique | NA | COMPLETED | Severe acquired brain injury (sABI) is a group of disorders that cause lon… À vérifier | ClinicalTrials.gov 2026-07-29 15:50:58 | Détail |
| Haemostasis tests NCT03424460 · DM1-VTE — Venous Thromboembolism in Myotonic Dystrophy Type 1 | Myopathies | À vérifier | NA | COMPLETED | Investigators identified a high risk of deep vein thrombosis and pulmonary… À vérifier | ClinicalTrials.gov 2026-07-29 15:50:58 | Détail |
| Prednisone NCT01169597 · Short Term Efficacy of a Starting Dose of 12.5 mg of Prednisone in Polymyalgia R… | Myopathies | À vérifier | Phase 4 | COMPLETED | The purpose of this study is to evaluate the efficacy and tolerability of… À vérifier | ClinicalTrials.gov 2026-07-29 15:50:58 | Détail |
| Radial extracorporeal shock wave therapy (rESWT) NCT02596659 · Effectiveness of Radial Extracorporeal Shockwave Therapy on Tennis Elbow | Myopathies | Immunomodulation · Traitement symptomatique | NA | COMPLETED | Background: Tennis elbow, also known as lateral epicondylitis, is the infl… À vérifier | ClinicalTrials.gov 2026-07-29 15:50:58 | Détail |
| Rehabilitation in Muscular Dystrophies From the Hospital Facility to… NCT06378203 · NCT06378203 | Myopathies | À vérifier | NA | UNKNOWN | Until twenty years ago physical exercise in muscular dystrophies was consi… À vérifier | ClinicalTrials.gov 2026-07-29 15:50:58 | Détail |
| SRP-9003 NCT05876780 · A Gene Transfer Single Dose Study to Evaluate the Safety, Tolerability and Effic… | Myopathies | À vérifier | Phase 1 | ACTIVE_NOT_RECRUITING | The primary purpose of this study is to evaluate the safety of SRP-9003 an… À vérifier | ClinicalTrials.gov 2026-07-29 15:50:58 | Détail |
| Mobile neural decoding platform (mobile iBCI) Étude non communiquée | Myopathies · Sclérose latérale amyotrophique | À vérifier | Non applicable | Prévu | Description non affichée : incohérence de maladie détectée. Consultez l’es… À vérifier | ClinicalTrials.gov 2026-07-23 | Détail |
| Drisapersen NCT02636686 · Extension Study of Drisapersen in DMD Subjects | Myopathies | À vérifier | À vérifier | NO_LONGER_AVAILABLE | This is a phase IIIb, multi-centre, open-label extension study in male sub… À vérifier | ClinicalTrials.gov 2026-07-22 21:19:38 | Détail |
| Effectiveness of Multicomponent Treatment for Fibromyalgia (FIBROWALK) NCT04284566 · NCT04284566 | Myopathies | À vérifier | NA | COMPLETED | The main objective of this study is to analyse the effectiveness of the FI… À vérifier | ClinicalTrials.gov 2026-07-22 21:19:38 | Détail |
| Effects of a 12-week Strength Training Program in Women With Myotonic… NCT05400629 · NCT05400629 | Myopathies | À vérifier | NA | COMPLETED | 20 women with myotonic dystrophy type 1 (DM1) will complete a 12-week lowe… À vérifier | ClinicalTrials.gov 2026-07-22 21:19:38 | Détail |
| High molecular weight hylan (Synvisc) injection NCT00078351 · Synvisc to Treat Osteoarthritis of the Temporomandibular Joint | Myopathies | Traitement symptomatique | Phase 2 | COMPLETED | This study will examine the effectiveness of injected hylan (Synvisc) for… À vérifier | ClinicalTrials.gov 2026-07-22 21:19:38 | Détail |
| Musculoskeletal Nociceptive Pain in Participants With Neuromuscular D… NCT04907162 · NCT04907162 | Myopathies | Traitement symptomatique | À vérifier | COMPLETED | The primary aim is to characterize the prevalence, severity and quality of… À vérifier | ClinicalTrials.gov 2026-07-22 21:19:38 | Détail |
| RO7204239 NCT05548556 · MANOEUVRE — A Study to Evaluate RO7204239 in Participants With Facioscapulohumer… | Myopathies | À vérifier | Phase 2 | ACTIVE_NOT_RECRUITING | The purpose of this study is to evaluate the pharmacodynamics, safety, tol… À vérifier | ClinicalTrials.gov 2026-07-22 21:19:38 | Détail |
| TRANSIMMUNOM — Phenomics in Autoimmune and Inflammatory Diseases NCT02466217 · NCT02466217 | Myopathies | Immunomodulation | À vérifier | COMPLETED | The family of inflammatory/autoimmune systemic diseases (IAD) form a conti… À vérifier | ClinicalTrials.gov 2026-07-22 21:19:38 | Détail |
| AioCare spirometer NCT05516745 · E-PULMoDMD — E-monitoring of PULMonary Function in Patients With Duchenne Muscul… | Myopathies | À vérifier | NA | UNKNOWN | Duchenne muscular dystrophy (DMD) is the most common, progressive, irrever… À vérifier | ClinicalTrials.gov 2026-07-18 15:45:08 | Détail |
| BMN 044 IV 6 mg/kg NCT02958202 · Extension Study of BMN 044 in Duchenne Muscular Dystrophy (DMD) | Myopathies | À vérifier | Phase 2 | TERMINATED | The aim of this study is to provide continuing access to BMN 044 treatment… À vérifier | ClinicalTrials.gov 2026-07-18 15:45:08 | Détail |
| Kinesiology tape NCT03541070 · The Effect of Kinesiology Taping on Balance in Duchenne Muscular Dystrophy | Myopathies | À vérifier | NA | COMPLETED | Investigators investigated that the effects of kinesilogy taping on balanc… À vérifier | ClinicalTrials.gov 2026-07-18 15:45:08 | Détail |
| Non-invasive Neuromodulation NCT05648695 · Efficacy of Non-invasive NESA Neuromodulation in Fibromyalgia | Myopathies | Traitement symptomatique | NA | COMPLETED | Fibromyalgia is a chronic condition that causes pain throughout the body,… À vérifier | ClinicalTrials.gov 2026-07-18 15:45:08 | Détail |
| Effects of Newly-created Individualized Upper Airway Muscle Functiona… NCT05346705 · NCT05346705 | Myopathies | Traitement symptomatique | NA | UNKNOWN | Objectives: To observe the effect of newly-created individualized upper ai… À vérifier | ClinicalTrials.gov 2026-07-18 15:45:07 | Détail |
Découverte scientifique
Recherches et trouvailles 0
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune trouvaille ne correspond aux filtres. | |||||||
Bibliographie
Publications 585
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Tests of dynamic balance, motor function and fear of falling as indic… Fear of Falling in Muscular Dystrophy · PMID 40645042 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source This study aims to examine dynamic balance, motor function, and fear of falling (FOF) as indicators of fall risk in chi… | European journal of paediatric neurology : EJPN : offi… 2026-07-08 20:14:58 | Source |
| New insights into an old vaccine: potency and breadth of neutralizing… Yellow Fever vaccine (17D) · PMID 40766119 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source The yellow fever vaccine 17D has controlled yellow fever for almost 90 years and is considered highly successful. Howev… | medRxiv : the preprint server for health sciences 2026-07-08 20:14:57 | Source |
| New insights into an old vaccine: potency and breadth of neutralizing… Yellow Fever vaccine (17D) · PMID 41670061 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source The yellow fever vaccine 17D has controlled yellow fever for almost 90 years and is considered highly successful. Howev… | The Journal of infectious diseases 2026-07-08 20:14:57 | Source |
| Early mobilization in the neurotrauma intensive care unit: a service… The Impact of Early Mobilization Protocol in Patients in the ICU · PMID 42388707 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Early mobilization (EM) refers to active exercise commenced while patients are on the intensive care unit (ICU). Althou… | Frontiers in neurology 2026-07-08 20:14:56 | Source |
| Nursing-led stepwise pain-management protocol improves postoperative… The Impact of Early Mobilization Protocol in Patients in the ICU · PMID 42007103 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source To assess the impact of a stepwise pain-management protocol on postoperative recovery, pain control, complication rate,… | American journal of translational research 2026-07-08 20:14:56 | Source |
| Experiences of women with disabilities accessing maternal and newborn… Awareness Levels of Caregivers of Disabled Children · PMID 42192434 | Myopathies | Ralentissement de la progression · Thérapie génique | Publication | PubMed | Voir la publication source Despite global commitments to inclusive and equitable maternal and newborn health (MNH) care, women with disabilities i… | Reproductive health 2026-07-08 20:14:50 | Source |
| The effect of a mindfulness-based stress reduction program on stress… Awareness Levels of Caregivers of Disabled Children · PMID 42297152 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Mothers of children with physical disabilities often experience caregiving-related stress that may negatively affect th… | Journal of affective disorders 2026-07-08 20:14:50 | Source |
| One-day rejuvenation: a preliminary case series of a multimodal proto… Botulinum toxin type A · PMID 42418230 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Same-day multimodal aesthetic treatments may optimize patient convenience, but concerns remain regarding possible therm… | Journal of cosmetic and laser therapy : official publi… 2026-07-08 20:14:49 | Source |
| Activation of GABAR alleviates colitis by reprogramming macrophage po… baclofen · PMID 42413737 | Myopathies | Immunomodulation | Publication | PubMed | Voir la publication source Although the metabotropic GABA type B receptor (GABAR) has emerged as an immune modulator, its specific role in regulat… | Biochemical pharmacology 2026-07-08 20:14:47 | Source |
| Long-Term Effects of Early Postnatal Administration of R-Baclofen on… baclofen · PMID 42411441 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source Contactin-associated protein-like 2 () is a highly expressed gene during development, coding for the cell adhesion mole… | Journal of integrative neuroscience 2026-07-08 20:14:47 | Source |
| Intermittent Theta-Burst Stimulation and Depressive Symptoms in Major… Intermittent theta burst stimulation · PMID 42418203 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source Intermittent theta-burst stimulation (iTBS) is an established treatment for major depressive disorder (MDD), but sham-c… | JAMA network open 2026-07-08 20:14:19 | Source |
| Intermittent Theta-Burst Stimulation for Depression-Delineating Speci… Intermittent theta burst stimulation · PMID 42418204 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Résumé non disponible dans la base locale. | JAMA network open 2026-07-08 20:14:19 | Source |
| Feasibility and behavioral impact of a wearable-supported digital hea… test of walk · PMID 42416388 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source This proof-of-concept study examined whether wearable devices integrated with the Welloop mobile application and a ligh… | Digital health 2026-07-08 15:43:04 | Source |
| Five-Year Outcomes of Paclitaxel-Coated Balloons in Patients with Dia… test of walk · PMID 42416524 | Myopathies | Thérapie génique | Publication | PubMed | Voir la publication source Long-term outcomes of paclitaxel-coated drug-coated balloons (DCBs) in patients with diabetes mellitus (DM) and infrain… | Vascular health and risk management 2026-07-08 15:43:04 | Source |
| Disparities in deworming coverage between children with and without d… COVID-19 Pandemic and Parents of Disabled Children · PMID 42264499 | Myopathies | Ralentissement de la progression | Publication | PubMed | Voir la publication source Children with disabilities experience lower school enrolment rates and may be systematically excluded from school-based… | BMJ global health 2026-07-08 12:06:58 | Source |
| Neurodevelopmental treatment needs after severe acute respiratory syn… COVID-19 Pandemic and Parents of Disabled Children · PMID 42050906 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source ObjectiveThis cohort study examined whether documented coronavirus disease 2019 in young children affects the need for… | The Journal of international medical research 2026-07-08 12:06:58 | Source |
| Aquatic training improves muscle strength and functional mobility in… Manual muscular test · PMID 42398272 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Myotonic dystrophy type 1 (DM1) is the most common adult muscular dystrophy and is characterized by progressive muscle… | Neuromuscular disorders : NMD 2026-07-08 12:06:57 | Source |
| Gaming Technology in Pediatric Cerebral Palsy and Related Neuromuscul… Manual muscular test · PMID 42206959 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source BackgroundChildren with cerebral palsy (CP) and related neuromuscular conditions often experience barriers to physical… | NeuroRehabilitation 2026-07-08 12:06:57 | Source |
| The reliability and validity of the 30-second chair sit-to-stand test… test of walk · PMID 42414666 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source This study investigated the reliability and validity of the five-repetition sit-to-stand (5xSTS) and 30-second chair si… | European spine journal : official publication of the E… 2026-07-08 12:06:56 | Source |
| Yiqi Fumai Lyophilized Injection for Improving Exercise Tolerance in… test of walk · PMID 42413004 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source High mortality and prevalence rates are hallmarks of chronic heart failure (CHF). Patients frequently have a much lower… | JMIR research protocols 2026-07-08 12:06:56 | Source |
Exploration — prudence
Pistes exploratoires 6
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| N-PPG N-PPG — modulation métabolique cérébrale | Myopathies | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation métabolique et mitohormèse N-PPG est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être pertinents pour Myopat… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |
| Vecteur Ple389 (ADORA2A) MiniPromoter Ple389 — ciblage striatal | Myopathies | Thérapie génique | Hypothèse exploratoire | Rapprochement automatique non validé | Expression génique ciblée dans les neurones striataux Vecteur Ple389 (ADORA2A) est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être per… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |
| α-Amyrin α-Amyrin — protection mitochondriale | Myopathies | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Protection mitochondriale et modulation de la pathologie Tau α-Amyrin est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pour Myopa… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Myopathies | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation immunométabolique de la microglie 4-octyl itaconate et dérivés est étudié dans Sclérose latérale amyotrophique et documente plusieurs axes biologiques po… | Rapprochement Biomedical Watch · Sclérose latérale amy… | Détail |
| Thonningianin A Thonningianin A — neuroprotection anti-amyloïde | Myopathies | Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation du stress oxydatif et des protéines associées à Alzheimer Thonningianin A est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |
| Vutiglabridin Vutiglabridin — autophagie et PON2 | Myopathies | Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Activation de PON2 et stimulation de l’autophagie Vutiglabridin est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pour… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |