Vue transversale de la maladie
Migraine
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
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1236 résultats correspondants
· 45 visibles sur cette page
dans le périmètre Migraine
Niveau clinique
Études et traitements 570
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Nortriptyline NCT06799169 · Management of Acute Tinnitus With Migraine Medications | Migraine | À vérifier | Phase 4 | ACTIVE_NOT_RECRUITING | Tinnitus represents one of the most common and distressing otologic proble… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| PFOCUS — Neurogenetic And Hemodynamic Of Migraine Aura And Pfo NCT07349004 · NCT07349004 | Migraine | À vérifier | À vérifier | RECRUITING | The PFOCUS Study aims to clarify the relationship between patent foramen o… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Pituitary Adenylate Cyclase Activating Polypeptide-38 (PACAP-38) NCT07342296 · Induction of Migraine Attacks With Aura Using Pituitary Adenylate Cyclase Activa… | Migraine | À vérifier | Non applicable | NOT_YET_RECRUITING | Pituitary Adenylate Cyclase Activating Polypeptide-38 (PACAP-38) is a key… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Rimegepant NCT07667621 · A Prospective, Open-Label Study Evaluating the Effectiveness of Gepants for Acut… | Migraine | À vérifier | Phase 1 | NOT_YET_RECRUITING | The purpose of this study is to evaluate safety and tolerability of BHV-30… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Rimegepant 75 MG NCT06409832 · RAISE — RimegepAnt effectIvenesS and tolErability as Migraine Preventive Treatme… | Migraine | Traitement symptomatique | À vérifier | RECRUITING | In a real-world population of adults with migraine, the investigators woul… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Rimegepant 75 MG Disintegrating Oral Tablet NCT05903027 · Gepant treAtments: EffectIveNess and tolERability (GAINER) | Migraine | À vérifier | À vérifier | RECRUITING | The purpose of this prospective and multicentric study is to evaluate the… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Rimegepant sulfate NCT07497854 · Rimegepant PMS — A Study to Learn About the Study Medicine NURTEC® ODT 75 mg Aft… | Migraine | À vérifier | À vérifier | NOT_YET_RECRUITING | The purpose of this study is to evaluate safety and effectiveness of NURTE… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| The Sequestration of Holistic Stress Management Techniques for Adults NCT06098755 · NCT06098755 | Migraine | À vérifier | Non applicable | WITHDRAWN | This remote study is intended to assist the population with access to cost… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Transcutaneous Electrical Nerve Stimulation (TENS) NCT07015125 · Evaluation of a Wearable Device for Acute Treatment of Migraines | Migraine | Traitement symptomatique | Non applicable | COMPLETED | The goal of this clinical trial is to determine the efficacy of a new, imp… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Ubrogepant NCT05127954 · UBRO PEDS OLE — Long-term Extension Study to Assess Safety and Tolerability of O… | Migraine | À vérifier | Phase 3 | ENROLLING_BY_INVITATION | Migraine is a common neurological disorder typically characterized by atta… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Understanding the Pathophysiology of Migraine Pain NCT03026101 · NCT03026101 | Migraine | Traitement symptomatique · Thérapie génique | Non applicable | TERMINATED | Migraine is the most common headache disorder, prevalent in 18% of females… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Atogepant 60 mg NCT04686136 · A Long-Term Safety and Tolerability Extension Study Evaluating Atogepant for the… | Migraine | À vérifier | Phase 3 | COMPLETED | This goal of this study is to compare three medications used for migraine… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:11 | Détail |
| AURA — PERSONOLOGICAL STRUCTURE, COGNITIVE FUNCTIONS AND CENTRAL SENS… NCT07268768 · NCT07268768 | Migraine | Ralentissement de la progression · Traitement symptomatique | À vérifier | RECRUITING | Headache, in its episodic and chronic forms, cannot be considered solely a… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:11 | Détail |
| BOTOX NCT05028569 · Study of BOTOX Injections in Prevention of Migraine in Adult Participants With E… | Migraine | Thérapie génique | Phase 3 | TERMINATED | Migraine is a neurological disease characterized by moderate or severe hea… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:11 | Détail |
| Cabergoline 0.5 MG NCT07072910 · PROTECT — Cabergoline for Episodic Migraine | Migraine | À vérifier | Phase 2 | RECRUITING | The goal of this randomized, placebo-controlled, double-blind clinical tri… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:11 | Détail |
| Cerebri biofeedback NCT05616741 · BioCer — Home-based Biofeedback for the Prevention of Migraine | Migraine | À vérifier | Non applicable | COMPLETED | The goal of this clinical trial is to test an app-based biofeedback treatm… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:11 | Détail |
| INMEST-treatment NCT07279623 · A-MI-01 — Intra-Nasal Mechanical Stimulation (INMEST) as a Potential Preventativ… | Migraine | À vérifier | Non applicable | RECRUITING | This is a prospective, randomized, open-label, delayed-start clinical inve… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:11 | Détail |
| Rimegepant NCT05207865 · Safety and Tolerability Study of Daily Dosing Rimegepant in Episodic Migraine Pr… | Migraine | À vérifier | Phase 4 | COMPLETED | The purpose of this study is to evaluate safety and tolerability of BHV-30… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:11 | Détail |
| Rimegepant 75mg daily dosing NCT05217927 · Efficacy and Safety Study of Rimegepant in Episodic Migraine Prevention With Mul… | Migraine | À vérifier | Phase 4 | COMPLETED | The purpose of this study is to compare the efficacy and safety of daily a… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:11 | Détail |
| ViKEM — Vitamin K2 Supplementation in Adult Episodic Migraine NCT05943457 · NCT05943457 | Migraine | Ralentissement de la progression | Non applicable | RECRUITING | Migraine is a debilitating illness and a major cause of disability in the… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:11 | Détail |
Découverte scientifique
Recherches et trouvailles 0
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune trouvaille ne correspond aux filtres. | |||||||
Bibliographie
Publications 661
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Stephanoside B modulates metabolic gene expression and lengthens the… dexamethasone · PMID 42484698 | Migraine | Immunomodulation | Publication | PubMed | Voir la publication source Gymnema (G.) inodorum is a medicinal plant with anti-diabetic, anti-obesity, and anti-inflammatory properties tradition… | Molecular biology reports 2026-07-22 21:21:52 | Source |
| Peripheral nerve stimulation registry for intractable migraine headac… Relief — Peripheral Nerve Stimulation Registry for Intractable Migraine Headache · PMID 323779… | Migraine | Ralentissement de la progression | Publication | PubMed | Voir la publication source Migraine is common and ranked as the first cause of disability in people under fifty. Despite significant advances in i… | Acta neurochirurgica 2026-07-22 21:21:32 | Source |
| Comparison of Balanced General Anesthesia Protocols in Sleeve Gastrec… ketamine infusion · PMID 42455083 | Migraine | À vérifier | Publication | PubMed | Voir la publication source To evaluate the effects of two different anesthesia management techniques applied to sleeve gastrectomy patients on pos… | Journal of perianesthesia nursing : official journal o… 2026-07-22 21:21:31 | Source |
| Innovative integration of high dose ketamine infusion, psychological… ketamine infusion · PMID 42454590 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Ketamine is a noncompetitive antagonist of the N-methyl-D-aspartate receptor that has garnered significant interest as… | Pain management 2026-07-22 21:21:31 | Source |
| Atorvastatin Reduces Alcohol-Related Cardiac and Liver Tissue Damage,… Endothelin-1 · PMID 42478929 | Migraine | Remyélinisation indirecte / réparation · Neuroprotection · Immunomodulation | Publication | PubMed | Voir la publication source Excessive alcohol consumption causes significant cardio-hepatic damage. This study investigated the effects of standard… | Journal of biochemical and molecular toxicology 2026-07-22 21:21:29 | Source |
| Involvement of Mitophagy in Endothelin-1 Mediated Neurodegeneration i… Endothelin-1 · PMID 42465463 | Migraine | Remyélinisation indirecte / réparation | Publication | PubMed | Voir la publication source The ultimate cause of blindness in glaucoma is the death of retinal ganglion cells, and understanding the mechanism beh… | bioRxiv : the preprint server for biology 2026-07-22 21:21:29 | Source |
| Connexin 43 subcellular localization: From trafficking dynamics to pa… Tonabersat · PMID 42069098 | Migraine | Remyélinisation indirecte / réparation · Immunomodulation | Publication | PubMed | Voir la publication source Connexin 43 (Cx43) exhibits remarkable functional diversity that is precisely dictated by its dynamic subcellular local… | Cellular signalling 2026-07-22 21:21:28 | Source |
| Oral Tonabersat Connexin-43 Modulator for Diabetic Macular Edema with… Tonabersat · PMID 42064012 | Migraine | Immunomodulation | Publication | PubMed | Voir la publication source Evaluate oral tonabersat, a connexin-43 hemichannel modulator, on central subfield thickness (CST) in eyes with center-… | Ophthalmology science 2026-07-22 21:21:28 | Source |
| Cross-response to Calcitonin Gene-Related Peptide monoclonal antibodi… Eptinezumab 100 mg or Eptinezumab 300 mg administered intravenously in 100 mL saline solution… | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Real-world data on calcitonin gene-related peptide (CGRP) monoclonal antibodies (mAbs) are essential to determine wheth… | The journal of headache and pain 2026-07-22 21:21:27 | Source |
| Long-term treatment with Eptinezumab in special treatment situations:… Eptinezumab 100 mg or Eptinezumab 300 mg administered intravenously in 100 mL saline solution… | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source The neurotransmitter Calcitonin Gene related Peptide (CGRP) is one of the key players driving migraine attacks. Randomi… | Journal of the neurological sciences 2026-07-22 21:21:27 | Source |
| Chronic Migraine Pathophysiology and Treatment: A Review of Current P… HYPOTHAMIG — Hypothalamus Connectivity in Chronic and Episodic Migraine · PMID 35295486 | Migraine | Ralentissement de la progression · Immunomodulation | Publication | PubMed | Voir la publication source Chronic migraine is a disabling neurological disorder that imposes a considerable burden on individual and socioeconomi… | Frontiers in pain research (Lausanne, Switzerland) 2026-07-22 21:21:25 | Source |
| The role and interaction of hypothalamic-related neurotransmitters in… HYPOTHAMIG — Hypothalamus Connectivity in Chronic and Episodic Migraine · PMID 40350428 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Migraine is a complex neurological disorder frequently associated with hypothalamic dysfunction. This brain region is e… | The journal of headache and pain 2026-07-22 21:21:25 | Source |
| Design of active pharmaceutical ingredient-ionic liquids for enhanced… Non-steroidal anti-inflammatory drug (NSAID) · PMID 42364699 | Migraine | Immunomodulation | Publication | PubMed | Voir la publication source Active pharmaceutical ingredient ionic liquids (API-ILs) can enhance skin delivery by tuning physicochemical properties… | Journal of controlled release : official journal of th… 2026-07-22 21:21:24 | Source |
| Incidence of Heterotopic Ossification Following Double-Incision Techn… Non-steroidal anti-inflammatory drug (NSAID) · PMID 42438580 | Migraine | Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Background Heterotopic ossification (HO) is a postoperative finding that may occur after distal biceps tendon repair us… | Cureus 2026-07-22 21:21:24 | Source |
| Comparison of propranolol LA 80 mg and propranolol LA 160 mg in migra… propranolol LA · PMID 8495455 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Thirty patients with severe classical and common migraine participated in a double-blind placebo-controlled cross-over… | Cephalalgia : an international journal of headache 2026-07-22 21:21:23 | Source |
| Randomized, placebo-controlled trial of propranolol added to topirama… propranolol LA · PMID 22377815 | Migraine | À vérifier | Publication | PubMed | Voir la publication source To assess the efficacy and safety of adding propranolol to topiramate in chronic migraine subjects inadequately control… | Neurology 2026-07-22 21:21:23 | Source |
| Adjunctive transcranial DC stimulation in the management of refractor… DC Stimulator (Transcranial Direct Current Stimulator) · PMID 42248710 | Migraine | Remyélinisation indirecte / réparation | Publication | PubMed | Voir la publication source Pathogenic POLG variants produce an age-related progressive multi-system mitochondrial disorder, with neurologic manife… | Seizure 2026-07-22 21:21:22 | Source |
| Reducing state anxiety with alpha-frequency transcranial alternating… DC Stimulator (Transcranial Direct Current Stimulator) · PMID 42208813 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source Anxiety reactivity to acute stress is a transdiagnostic vulnerability factor. We tested whether a single session of alp… | Journal of affective disorders 2026-07-22 21:21:22 | Source |
| Innovation is not enough: lessons from lasmiditan for real-world effe… Lasmiditan · PMID 42415704 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Résumé non disponible dans la base locale. | Expert review of neurotherapeutics 2026-07-22 21:21:20 | Source |
| Regulation of mitochondrial biogenesis by the 5-HT1F receptor and its… Lasmiditan · PMID 42457119 | Migraine | Remyélinisation indirecte / réparation · Traitement symptomatique · Thérapie gé… | Publication | PubMed | Voir la publication source Muscle spasticity is among the common secondary complications in patients with spinal cord injury (SCI). On the basis o… | Neuroscience letters 2026-07-22 21:21:20 | Source |
Exploration — prudence
Pistes exploratoires 5
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Bavisant BRAVEinMS — Bavisant | Migraine | Remyélinisation · Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Antagonisme du récepteur H3 de l’histamine Bavisant est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migra… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| Tol-MP Tol-MP — tolérance immunitaire spécifique de la myéline | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Microparticules biodégradables chargées en rapamycine et fonctionnalisées… Tol-MP est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migrain… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| SetPoint System SetPoint System — SetPoint Medical | Migraine | Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | re ApplicationsPublicationsCompanyCareersNewsGet startedGet startedNewsThe… SetPoint System est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation immunométabolique de la microglie 4-octyl itaconate et dérivés est étudié dans Sclérose latérale amyotrophique et documente plusieurs axes biologiques po… | Rapprochement Biomedical Watch · Sclérose latérale amy… | Détail |
| N-PPG N-PPG — modulation métabolique cérébrale | Migraine | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation métabolique et mitohormèse N-PPG est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être pertinents pour Migrai… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |