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Migraine
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
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1236 résultats correspondants
· 45 visibles sur cette page
dans le périmètre Migraine
Niveau clinique
Études et traitements 570
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Nortriptyline NCT06799169 · Management of Acute Tinnitus With Migraine Medications | Migraine | À vérifier | Phase 4 | ACTIVE_NOT_RECRUITING | Tinnitus represents one of the most common and distressing otologic proble… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| PFOCUS — Neurogenetic And Hemodynamic Of Migraine Aura And Pfo NCT07349004 · NCT07349004 | Migraine | À vérifier | À vérifier | RECRUITING | The PFOCUS Study aims to clarify the relationship between patent foramen o… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Pituitary Adenylate Cyclase Activating Polypeptide-38 (PACAP-38) NCT07342296 · Induction of Migraine Attacks With Aura Using Pituitary Adenylate Cyclase Activa… | Migraine | À vérifier | Non applicable | NOT_YET_RECRUITING | Pituitary Adenylate Cyclase Activating Polypeptide-38 (PACAP-38) is a key… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Rimegepant NCT07667621 · A Prospective, Open-Label Study Evaluating the Effectiveness of Gepants for Acut… | Migraine | À vérifier | Phase 1 | NOT_YET_RECRUITING | The purpose of this study is to evaluate safety and tolerability of BHV-30… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Rimegepant 75 MG NCT06409832 · RAISE — RimegepAnt effectIvenesS and tolErability as Migraine Preventive Treatme… | Migraine | Traitement symptomatique | À vérifier | RECRUITING | In a real-world population of adults with migraine, the investigators woul… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Rimegepant 75 MG Disintegrating Oral Tablet NCT05903027 · Gepant treAtments: EffectIveNess and tolERability (GAINER) | Migraine | À vérifier | À vérifier | RECRUITING | The purpose of this prospective and multicentric study is to evaluate the… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Rimegepant sulfate NCT07497854 · Rimegepant PMS — A Study to Learn About the Study Medicine NURTEC® ODT 75 mg Aft… | Migraine | À vérifier | À vérifier | NOT_YET_RECRUITING | The purpose of this study is to evaluate safety and effectiveness of NURTE… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| The Sequestration of Holistic Stress Management Techniques for Adults NCT06098755 · NCT06098755 | Migraine | À vérifier | Non applicable | WITHDRAWN | This remote study is intended to assist the population with access to cost… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Transcutaneous Electrical Nerve Stimulation (TENS) NCT07015125 · Evaluation of a Wearable Device for Acute Treatment of Migraines | Migraine | Traitement symptomatique | Non applicable | COMPLETED | The goal of this clinical trial is to determine the efficacy of a new, imp… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Ubrogepant NCT05127954 · UBRO PEDS OLE — Long-term Extension Study to Assess Safety and Tolerability of O… | Migraine | À vérifier | Phase 3 | ENROLLING_BY_INVITATION | Migraine is a common neurological disorder typically characterized by atta… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Understanding the Pathophysiology of Migraine Pain NCT03026101 · NCT03026101 | Migraine | Traitement symptomatique · Thérapie génique | Non applicable | TERMINATED | Migraine is the most common headache disorder, prevalent in 18% of females… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Atogepant 60 mg NCT04686136 · A Long-Term Safety and Tolerability Extension Study Evaluating Atogepant for the… | Migraine | À vérifier | Phase 3 | COMPLETED | This goal of this study is to compare three medications used for migraine… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:11 | Détail |
| AURA — PERSONOLOGICAL STRUCTURE, COGNITIVE FUNCTIONS AND CENTRAL SENS… NCT07268768 · NCT07268768 | Migraine | Ralentissement de la progression · Traitement symptomatique | À vérifier | RECRUITING | Headache, in its episodic and chronic forms, cannot be considered solely a… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:11 | Détail |
| BOTOX NCT05028569 · Study of BOTOX Injections in Prevention of Migraine in Adult Participants With E… | Migraine | Thérapie génique | Phase 3 | TERMINATED | Migraine is a neurological disease characterized by moderate or severe hea… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:11 | Détail |
| Cabergoline 0.5 MG NCT07072910 · PROTECT — Cabergoline for Episodic Migraine | Migraine | À vérifier | Phase 2 | RECRUITING | The goal of this randomized, placebo-controlled, double-blind clinical tri… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:11 | Détail |
| Cerebri biofeedback NCT05616741 · BioCer — Home-based Biofeedback for the Prevention of Migraine | Migraine | À vérifier | Non applicable | COMPLETED | The goal of this clinical trial is to test an app-based biofeedback treatm… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:11 | Détail |
| INMEST-treatment NCT07279623 · A-MI-01 — Intra-Nasal Mechanical Stimulation (INMEST) as a Potential Preventativ… | Migraine | À vérifier | Non applicable | RECRUITING | This is a prospective, randomized, open-label, delayed-start clinical inve… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:11 | Détail |
| Rimegepant NCT05207865 · Safety and Tolerability Study of Daily Dosing Rimegepant in Episodic Migraine Pr… | Migraine | À vérifier | Phase 4 | COMPLETED | The purpose of this study is to evaluate safety and tolerability of BHV-30… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:11 | Détail |
| Rimegepant 75mg daily dosing NCT05217927 · Efficacy and Safety Study of Rimegepant in Episodic Migraine Prevention With Mul… | Migraine | À vérifier | Phase 4 | COMPLETED | The purpose of this study is to compare the efficacy and safety of daily a… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:11 | Détail |
| ViKEM — Vitamin K2 Supplementation in Adult Episodic Migraine NCT05943457 · NCT05943457 | Migraine | Ralentissement de la progression | Non applicable | RECRUITING | Migraine is a debilitating illness and a major cause of disability in the… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:11 | Détail |
Découverte scientifique
Recherches et trouvailles 0
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune trouvaille ne correspond aux filtres. | |||||||
Bibliographie
Publications 661
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Blocking the CGRP Receptor: Differences across Human Vascular Beds. Telcagepant · PMID 37630989 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Multiple drugs targeting the calcitonin gene-related peptide (CGRP) receptor have been developed for the treatment of m… | Pharmaceuticals (Basel, Switzerland) 2026-08-08 00:59:15 | Source |
| CGRP receptor antagonists (gepants). Telcagepant · PMID 38307667 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Small molecule calcitonin gene-related peptide (CGRP) receptor antagonists are commonly referred to as gepants. The fir… | Handbook of clinical neurology 2026-08-08 00:59:15 | Source |
| Species-specific functions of CSRP3 in satellite cell-driven muscle r… SCS · PMID 42566102 | Migraine | Remyélinisation indirecte / réparation · Thérapie cellulaire | Publication | PubMed | Voir la publication source Skeletal muscle function deteriorates with injury, disease, or aging. While stem cell therapies offer therapeutic poten… | Cell regeneration (London, England) 2026-08-08 00:59:14 | Source |
| Spinal cord stimulation effects on restless legs syndrome: A single c… SCS · PMID 42566390 | Migraine | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Restless legs syndrome (RLS) is a lifelong disorder characterized by recurrent, uncomfortable sensations and irresistib… | Stereotactic and functional neurosurgery 2026-08-08 00:59:14 | Source |
| Non-O blood groups as independent predictors of chronic subdural hema… Middle Meningeal Artery embolization · PMID 42566780 | Migraine | Ralentissement de la progression · Traitement symptomatique | Publication | PubMed | Voir la publication source Recurrence after surgical treatment of chronic subdural hematoma (CSDH) remains insufficiently understood. Microvascula… | Journal of neurosurgery 2026-08-08 00:59:13 | Source |
| Traumatic intracranial pseudoaneurysms of cortical middle cerebral ar… Middle Meningeal Artery embolization · PMID 42559449 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Traumatic intracranial pseudoaneurysms (TIPAs) are exceedingly rare, representing <1% of all intracranial aneurysms, an… | Surgical neurology international 2026-08-08 00:59:13 | Source |
| Dual Stellate Ganglion Blocks for Managing Treatment-Resistant Anxiet… Sham Procedure · PMID 42550523 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Anxiety disorders are associated with a high burden of illness. In patients with treatment-resistant anxiety disorder,… | Pain physician 2026-08-08 00:59:12 | Source |
| Novel neonatal hypoxic-ischemic model demonstrates glial activation a… Sham Procedure · PMID 42547840 | Migraine | Ralentissement de la progression · Immunomodulation | Publication | PubMed | Voir la publication source Neonatal global hypoxic-ischemic cerebral injury is a leading cause of infant mortality and lifelong disability. Curren… | Pediatric research 2026-08-08 00:59:12 | Source |
| Onabotulinumtoxin A Is an Effective Preventative Treatment of Chronic… Rimegepant · PMID 42541839 | Migraine | Ralentissement de la progression · Traitement symptomatique | Publication | PubMed | Voir la publication source Despite high efficacy and favorable safety profile in adults, Onabotulinumtoxin A (ONA) injections have not been Food a… | Pediatric neurology 2026-08-08 00:59:11 | Source |
| [Effectiveness and Risk of Recurrence of Pulsed Radiofrequency in Tri… Pulsed Radiofrequency of the Sphenopalatine Ganglion · PMID 42216458 | Migraine | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Percutaneous pulsed radiofrequency (PPRF) is a minimally invasive neuromodulation technique used in chronic pain manage… | Revista de neurologia 2026-08-08 00:59:11 | Source |
| Chronic Migraine Resistance: A Case Report Highlights an Overlooked F… eletriptan · PMID 42450884 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Chronic migraine may seem treatment-resistant when underlying medication-overuse headache (MOH) and psychosocial stress… | Healthcare (Basel, Switzerland) 2026-08-08 00:59:10 | Source |
| Eletriptan HBr-loaded solid lipid nanoparticle-integrated microneedle… eletriptan · PMID 42307459 | Migraine | Immunomodulation | Publication | PubMed | Voir la publication source Eletriptan hydrobromide (EHBr) exhibits poor oral bioavailability due to extensive first-pass metabolism by CYP3A4 and… | Journal of drug targeting 2026-08-08 00:59:10 | Source |
| Debris Flow Detection System Based on Tree-Topology Optical Fiber Net… Flow Detection System · PMID 42515294 | Migraine | À vérifier | Publication | PubMed | Voir la publication source This report proposes a debris flow detection system based on an optical fiber network. Optical communication devices, i… | Sensors (Basel, Switzerland) 2026-08-08 00:59:09 | Source |
| SFARP: a multi-layered real-time security framework for hybrid ARP an… Flow Detection System · PMID 41365983 | Migraine | À vérifier | Publication | PubMed | Voir la publication source The rapid expansion of Software-Defined Internet of Things (SD-IoT) networks has amplified both scalability and vulnera… | Scientific reports 2026-08-08 00:59:09 | Source |
| Review: An Update on CGRP Monoclonal Antibodies for the Preventive Tr… ALD403 · PMID 39998706 | Migraine | À vérifier | Publication | PubMed | Voir la publication source CGRP targeting therapies have revolutionized the migraine preventive space, introducing novel migraine-specific therapi… | Current pain and headache reports 2026-08-08 00:59:07 | Source |
| Effectiveness of acupuncture and related therapies for post-stroke in… Acupuncture · PMID 42566606 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Poststroke insomnia is often associated with poor recovery. Acupuncture (Acu) and related therapies offer have notable… | Medicine 2026-08-08 00:59:06 | Source |
| Frontal Delta Decreasing and Occipital Ictal Alpha Increasing Associa… PREDI-CRISIS — Migraine Attack Pain Phase Prediction Study · PMID 42166268 | Migraine | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Subtle changes across different migraine phases in resting electroencephalography (EEG) studies are commonly observed i… | IEEE transactions on neural systems and rehabilitation… 2026-08-08 00:59:06 | Source |
| The role of prodromal symptoms in predicting headache onset: A longit… PREDI-CRISIS — Migraine Attack Pain Phase Prediction Study · PMID 42260720 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source This longitudinal observational study investigated the role of prodromal symptoms in predicting headache onset, using e… | Headache 2026-08-08 00:59:06 | Source |
| Assessing the effectiveness of greater occipital nerve block in chron… Greater Occipital Nerve Block (GONB) · PMID 39244547 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source Chronic migraine poses a global health burden, particularly affecting young women, and has substantial societal implica… | BMC neurology 2026-08-08 00:59:05 | Source |
| Comparison of the Effectiveness of Greater Occipital Nerve Block and… Greater Occipital Nerve Block (GONB) · PMID 42005143 | Migraine | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Background Chronic migraine, defined as ≥15 headache days/month with ≥8 migraine days, is a disabling condition with li… | Cureus 2026-08-08 00:59:05 | Source |
Exploration — prudence
Pistes exploratoires 5
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Bavisant BRAVEinMS — Bavisant | Migraine | Remyélinisation · Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Antagonisme du récepteur H3 de l’histamine Bavisant est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migra… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| Tol-MP Tol-MP — tolérance immunitaire spécifique de la myéline | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Microparticules biodégradables chargées en rapamycine et fonctionnalisées… Tol-MP est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migrain… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| SetPoint System SetPoint System — SetPoint Medical | Migraine | Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | re ApplicationsPublicationsCompanyCareersNewsGet startedGet startedNewsThe… SetPoint System est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation immunométabolique de la microglie 4-octyl itaconate et dérivés est étudié dans Sclérose latérale amyotrophique et documente plusieurs axes biologiques po… | Rapprochement Biomedical Watch · Sclérose latérale amy… | Détail |
| N-PPG N-PPG — modulation métabolique cérébrale | Migraine | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation métabolique et mitohormèse N-PPG est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être pertinents pour Migrai… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |