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Migraine
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
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1236 résultats correspondants
· 45 visibles sur cette page
dans le périmètre Migraine
Niveau clinique
Études et traitements 570
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Nortriptyline NCT06799169 · Management of Acute Tinnitus With Migraine Medications | Migraine | À vérifier | Phase 4 | ACTIVE_NOT_RECRUITING | Tinnitus represents one of the most common and distressing otologic proble… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| PFOCUS — Neurogenetic And Hemodynamic Of Migraine Aura And Pfo NCT07349004 · NCT07349004 | Migraine | À vérifier | À vérifier | RECRUITING | The PFOCUS Study aims to clarify the relationship between patent foramen o… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Pituitary Adenylate Cyclase Activating Polypeptide-38 (PACAP-38) NCT07342296 · Induction of Migraine Attacks With Aura Using Pituitary Adenylate Cyclase Activa… | Migraine | À vérifier | Non applicable | NOT_YET_RECRUITING | Pituitary Adenylate Cyclase Activating Polypeptide-38 (PACAP-38) is a key… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Rimegepant NCT07667621 · A Prospective, Open-Label Study Evaluating the Effectiveness of Gepants for Acut… | Migraine | À vérifier | Phase 1 | NOT_YET_RECRUITING | The purpose of this study is to evaluate safety and tolerability of BHV-30… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Rimegepant 75 MG NCT06409832 · RAISE — RimegepAnt effectIvenesS and tolErability as Migraine Preventive Treatme… | Migraine | Traitement symptomatique | À vérifier | RECRUITING | In a real-world population of adults with migraine, the investigators woul… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Rimegepant 75 MG Disintegrating Oral Tablet NCT05903027 · Gepant treAtments: EffectIveNess and tolERability (GAINER) | Migraine | À vérifier | À vérifier | RECRUITING | The purpose of this prospective and multicentric study is to evaluate the… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Rimegepant sulfate NCT07497854 · Rimegepant PMS — A Study to Learn About the Study Medicine NURTEC® ODT 75 mg Aft… | Migraine | À vérifier | À vérifier | NOT_YET_RECRUITING | The purpose of this study is to evaluate safety and effectiveness of NURTE… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| The Sequestration of Holistic Stress Management Techniques for Adults NCT06098755 · NCT06098755 | Migraine | À vérifier | Non applicable | WITHDRAWN | This remote study is intended to assist the population with access to cost… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Transcutaneous Electrical Nerve Stimulation (TENS) NCT07015125 · Evaluation of a Wearable Device for Acute Treatment of Migraines | Migraine | Traitement symptomatique | Non applicable | COMPLETED | The goal of this clinical trial is to determine the efficacy of a new, imp… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Ubrogepant NCT05127954 · UBRO PEDS OLE — Long-term Extension Study to Assess Safety and Tolerability of O… | Migraine | À vérifier | Phase 3 | ENROLLING_BY_INVITATION | Migraine is a common neurological disorder typically characterized by atta… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Understanding the Pathophysiology of Migraine Pain NCT03026101 · NCT03026101 | Migraine | Traitement symptomatique · Thérapie génique | Non applicable | TERMINATED | Migraine is the most common headache disorder, prevalent in 18% of females… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Atogepant 60 mg NCT04686136 · A Long-Term Safety and Tolerability Extension Study Evaluating Atogepant for the… | Migraine | À vérifier | Phase 3 | COMPLETED | This goal of this study is to compare three medications used for migraine… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:11 | Détail |
| AURA — PERSONOLOGICAL STRUCTURE, COGNITIVE FUNCTIONS AND CENTRAL SENS… NCT07268768 · NCT07268768 | Migraine | Ralentissement de la progression · Traitement symptomatique | À vérifier | RECRUITING | Headache, in its episodic and chronic forms, cannot be considered solely a… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:11 | Détail |
| BOTOX NCT05028569 · Study of BOTOX Injections in Prevention of Migraine in Adult Participants With E… | Migraine | Thérapie génique | Phase 3 | TERMINATED | Migraine is a neurological disease characterized by moderate or severe hea… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:11 | Détail |
| Cabergoline 0.5 MG NCT07072910 · PROTECT — Cabergoline for Episodic Migraine | Migraine | À vérifier | Phase 2 | RECRUITING | The goal of this randomized, placebo-controlled, double-blind clinical tri… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:11 | Détail |
| Cerebri biofeedback NCT05616741 · BioCer — Home-based Biofeedback for the Prevention of Migraine | Migraine | À vérifier | Non applicable | COMPLETED | The goal of this clinical trial is to test an app-based biofeedback treatm… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:11 | Détail |
| INMEST-treatment NCT07279623 · A-MI-01 — Intra-Nasal Mechanical Stimulation (INMEST) as a Potential Preventativ… | Migraine | À vérifier | Non applicable | RECRUITING | This is a prospective, randomized, open-label, delayed-start clinical inve… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:11 | Détail |
| Rimegepant NCT05207865 · Safety and Tolerability Study of Daily Dosing Rimegepant in Episodic Migraine Pr… | Migraine | À vérifier | Phase 4 | COMPLETED | The purpose of this study is to evaluate safety and tolerability of BHV-30… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:11 | Détail |
| Rimegepant 75mg daily dosing NCT05217927 · Efficacy and Safety Study of Rimegepant in Episodic Migraine Prevention With Mul… | Migraine | À vérifier | Phase 4 | COMPLETED | The purpose of this study is to compare the efficacy and safety of daily a… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:11 | Détail |
| ViKEM — Vitamin K2 Supplementation in Adult Episodic Migraine NCT05943457 · NCT05943457 | Migraine | Ralentissement de la progression | Non applicable | RECRUITING | Migraine is a debilitating illness and a major cause of disability in the… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:11 | Détail |
Découverte scientifique
Recherches et trouvailles 0
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune trouvaille ne correspond aux filtres. | |||||||
Bibliographie
Publications 661
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Retrospective study on affecting factors and predictive model for gui… PFO occlusion · PMID 41630323 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Patent foramen ovale (PFO) is a common congenital cardiac anomaly. Transcatheter closure is effective, but guidewire pa… | Medicine 2026-08-16 13:11:54 | Source |
| Increased morning cortisol after ketamine treatment for suicidal depr… ketamine infusion · PMID 42349524 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Depression and its severe outcomes, suicidal ideation and behavior, are exacerbated by stress. A broad literature links… | Journal of affective disorders 2026-08-16 13:11:50 | Source |
| Peri-operative opioid analgesic requirements in dogs undergoing hemil… ketamine infusion · PMID 42061330 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Résumé non disponible dans la base locale. | Research in veterinary science 2026-08-16 13:11:50 | Source |
| Safety and Efficacy of the Prescribing Practices of Ketamine for Pain… ketamine infusion · PMID 41546137 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Ketamine has analgesic and sedative properties that are thought to reduce opioid tolerance and opioid-induced hyperalge… | The Annals of pharmacotherapy 2026-08-16 13:11:50 | Source |
| Acute stress alters prefrontal resting-state networks and tES restore… Transcranial electrical stimulation · PMID 42142754 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Acute stress is known to alter resting-state brain connectivity. However, the specific effects on prefrontal networks a… | Journal of affective disorders 2026-08-16 13:11:46 | Source |
| Multimodal intraoperative monitoring of facial nerve function: combin… Transcranial electrical stimulation · PMID 42407405 | Migraine | À vérifier | Publication | PubMed | Voir la publication source To compare the intraoperative blink reflex (BR) and facial corticobulbar motor evoked potentials (FCoMEPs) in skull bas… | Clinical neurophysiology : official journal of the Int… 2026-08-16 13:11:46 | Source |
| Combination Pharmacotherapies for Obesity-Current Evidence and Future… Amylin · PMID 42581493 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Conventional single-agent drugs yield modest, plateauing weight loss and often lead to weight regain. Combination pharm… | Endocrinology, diabetes & metabolism 2026-08-16 13:11:45 | Source |
| Shared pathophysiology and therapeutic repurposing in Alzheimer's dis… Amylin · PMID 42247872 | Migraine | Neuroprotection | Publication | PubMed | Voir la publication source Alzheimer's disease (AD) and type 2 diabetes mellitus (T2DM) are two prevalent age-related disorders that share strikin… | Bioorganic chemistry 2026-08-16 13:11:45 | Source |
| Heterogeneity in the efficacy of bosentan for hypertensive nephropath… Endothelin-1 · PMID 41649882 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Many patients with hypertensive nephropathy progress to chronic kidney disease (CKD). Targeting the core pathophysiolog… | Annals of medicine 2026-08-16 13:11:44 | Source |
| Serum endothelin-1 and endothelin-2 levels in healthy controls and ci… Endothelin-1 · PMID 41774498 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source The aim of this study was to evaluate serum endothelin-1 (ET-1) and endothelin-2 (ET-2) levels in patients with dipper… | Clinical and experimental hypertension (New York, N.Y.… 2026-08-16 13:11:44 | Source |
| The correlation between serum endothelin-1 levels and aortic stiffnes… Endothelin-1 · PMID 41820016 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Increased aortic stiffness (AS) is a recognized predictor of cardiovascular morbidity and mortality in patients with ch… | Renal failure 2026-08-16 13:11:44 | Source |
| Cilostazol in a Child With Moyamoya Disease. Cilostazol · PMID 41505343 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source Moyamoya disease is characterized by progressive stenosis of the terminal internal carotid arteries and their branches… | Journal of child neurology 2026-08-16 13:11:43 | Source |
| Prognostic implications of single antiplatelet therapy in individuals… Cilostazol · PMID 41981998 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Antiplatelet therapy is recommended for secondary prevention in patients with diabetes and peripheral arterial disease… | Annals of medicine 2026-08-16 13:11:43 | Source |
| Secondary prevention strategies for patients with lower extremity per… Cilostazol · PMID 42069036 | Migraine | Ralentissement de la progression · Traitement symptomatique | Publication | PubMed | Voir la publication source Individuals with lower extremity peripheral artery disease (LE PAD) represent a subset of patients with atherosclerotic… | American heart journal 2026-08-16 13:11:43 | Source |
| Antiseizure Medications that Did Not Reach the Epilepsy Market: An As… Tonabersat · PMID 41764707 | Migraine | À vérifier | Publication | PubMed | Voir la publication source The EILAT Conferences on New Antiepileptic Drugs (AEDs), which have taken place biennially since 1992, have traditional… | Drugs 2026-08-16 13:11:37 | Source |
| Migraine with visual aura, unilateral mydriasis and Takotsubo Syndrom… HYPOTHAMIG — Hypothalamus Connectivity in Chronic and Episodic Migraine · PMID 42597549 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source The recent examination of a woman who presented a migraine attack with visual aura and unilateral mydriasis, followed,… | Frontiers in neurology 2026-08-16 13:11:30 | Source |
| Diagnosis and management of migraine in adults: a population-based st… Triptan · PMID 41513289 | Migraine | Immunomodulation · Thérapie génique | Publication | PubMed | Voir la publication source Previous work has highlighted that migraine is underdiagnosed and undertreated in primary care. To characterise diagnos… | BJGP open 2026-08-16 13:11:29 | Source |
| Prescription practices and reasons for referral to tertiary care amon… Triptan · PMID 42247799 | Migraine | À vérifier | Publication | PubMed | Voir la publication source To evaluate prescription patterns, referral reasons, patient profiles, diagnostic accuracy, treatment adequacy, and sat… | Journal of clinical neuroscience : official journal of… 2026-08-16 13:11:29 | Source |
| Stroke in combined hormonal contraceptive users treated with triptans. Triptan · PMID 41932373 | Migraine | À vérifier | Publication | PubMed | Voir la publication source The extent of triptan use among users of combined hormonal contraceptives (CHC) is unknown. Likewise, it is unclear whe… | Contraception 2026-08-16 13:11:29 | Source |
| Elucidation of a novel fungal biotransformation pathway of ibuprofen… Non-steroidal anti-inflammatory drug (NSAID) · PMID 42251002 | Migraine | Immunomodulation | Publication | PubMed | Voir la publication source Ibuprofen, a widely used non-steroidal anti-inflammatory drug (NSAID), has been detected in the environment and is know… | Journal of bioscience and bioengineering 2026-08-16 13:11:28 | Source |
Exploration — prudence
Pistes exploratoires 5
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Bavisant BRAVEinMS — Bavisant | Migraine | Remyélinisation · Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Antagonisme du récepteur H3 de l’histamine Bavisant est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migra… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| Tol-MP Tol-MP — tolérance immunitaire spécifique de la myéline | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Microparticules biodégradables chargées en rapamycine et fonctionnalisées… Tol-MP est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migrain… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| SetPoint System SetPoint System — SetPoint Medical | Migraine | Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | re ApplicationsPublicationsCompanyCareersNewsGet startedGet startedNewsThe… SetPoint System est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation immunométabolique de la microglie 4-octyl itaconate et dérivés est étudié dans Sclérose latérale amyotrophique et documente plusieurs axes biologiques po… | Rapprochement Biomedical Watch · Sclérose latérale amy… | Détail |
| N-PPG N-PPG — modulation métabolique cérébrale | Migraine | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation métabolique et mitohormèse N-PPG est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être pertinents pour Migrai… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |