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Myopathies
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
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1012 résultats correspondants
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dans le périmètre Myopathies
Niveau clinique
Études et traitements 421
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Track-DM — An Ambispective Natural History Study in Myotonic Dystroph… NCT07732439 · Track-DM — An Ambispective Natural History Study in Myotonic Dystrophy Patients… | Myopathies | Traitement symptomatique | À vérifier | NOT_YET_RECRUITING | This natural history observational study is being conducted to follow pati… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:36 | Détail |
| Vamorolone NCT06564974 · DMD-001 SUMMIT — Registry Study to Observe Long-term Safety of Vamorolone (AGAMR… | Myopathies | À vérifier | À vérifier | RECRUITING | The goal of this study is to collect additional information on the safety… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:36 | Détail |
| A Clinical Trial to Evaluate the Effects of Peptide Gummies on Marker… NCT07752381 · NCT07752381 | Myopathies | Immunomodulation | Non applicable | COMPLETED | This study will evaluate the effects of Parlay Recover peptide gummies (co… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:35 | Détail |
| Myofascial Release and Positional Release Techniques in Unilateral Tr… NCT07515352 · NCT07515352 | Myopathies | Ralentissement de la progression · Traitement symptomatique | Non applicable | COMPLETED | Unilateral trapezitis is characterized by upper trapezius myofascial pain… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:35 | Détail |
| Pimicotinib NCT07499362 · Study of Pimicotinib in Japanese Participants With Tenosynovial Giant Cell Tumor… | Myopathies | Immunomodulation | Phase 2 | RECRUITING | The primary purpose of this study is to assess the tolerability, pharmacok… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:35 | Détail |
| the — Eccentric vs Low-Load Blood Flow Restriction Training in Knee O… NCT07733518 · NCT07733518 | Myopathies | Ralentissement de la progression | Non applicable | RECRUITING | The aim of this randomized controlled trial is to find the effects of ecce… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:35 | Détail |
| Yoomi Physical Therapy Software NCT05815017 · YOOMI: Effect of Gamified Physical Therapy Exercise Software on Inpatient Mobili… | Myopathies | À vérifier | Non applicable | COMPLETED | Patients admitted to the hospital often develop functional impairments due… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:35 | Détail |
| 3 Year Follow up on ANO5 Patients NCT05206617 · NCT05206617 | Myopathies | Ralentissement de la progression | À vérifier | ACTIVE_NOT_RECRUITING | The aim of the study is to investigate progression in muscle affection in… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| ANO5 MRI — MRI-phenotyping of Patients With Pathogenic Anoctamin 5 Va… NCT05102799 · NCT05102799 | Myopathies | Thérapie génique | À vérifier | ACTIVE_NOT_RECRUITING | A large cohort of MRI scans from patients with pathogenic variants in the… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| Apitegromab NCT07435129 · Phase 2 Study Evaluating Apitegromab for the Treatment of FSHD | Myopathies | À vérifier | Phase 2 | RECRUITING | A randomized Phase 2 study to evaluate the efficacy and safety of apitegro… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| Botulinum toxin type A NCT07758322 · Efficacy of Focused Shock Wave Therapy Before and After Botulinum Toxin Injectio… | Myopathies | Traitement symptomatique | Non applicable | ACTIVE_NOT_RECRUITING | The main purpose of this study is to determine which is the best dose of a… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| Constant Current Stimulator NCT07715006 · Dorsal Root Electrical Stimulation in Children With Cerebral Palsy | Myopathies | Traitement symptomatique | Non applicable | RECRUITING | The goal of this clinical trial is to evaluate whether dorsal root electri… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| Conventional Stabilization Splints NCT07760428 · Comparison of Conventional,3D Printed and Novel Hybrid Stabilization Splints in… | Myopathies | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | Occlusal splint therapy is a well-established conservative approach for th… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| delpacibart zotadirsen NCT07250737 · Managed Access Program for Del-zota in Participants With DMD Mutations Amenable… | Myopathies | À vérifier | À vérifier | AVAILABLE | The purpose of this Managed Access Program is to allow access to delpaciba… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| DNA Methylation in PMR NCT07748195 · NCT07748195 | Myopathies | À vérifier | À vérifier | NOT_YET_RECRUITING | Polymyalgia Rheumatica (PMR) is treated with corticosteroids; however, lon… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| Dry Needling NCT07321483 · Reflex Therapy of Temporomandibular Dysfunctions | Myopathies | Traitement symptomatique | Non applicable | RECRUITING | This randomized clinical trial will aim to compare the effectiveness of dr… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| Dual-task cycling NCT07580365 · VirtualPark_Pediatric | Myopathies | À vérifier | Non applicable | RECRUITING | The goal of this clinical trial is to assess the effects of a dual-task, m… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| Effects of Curcumin-Piperine Supplementation in Fibromyalgia NCT07753018 · NCT07753018 | Myopathies | Neuroprotection · Immunomodulation · Traitement symptomatique | Phase 2 | NOT_YET_RECRUITING | The goal of this clinical trail is to evaluate the effectiveness and safet… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| Effects of Pilates and Desk-Based Exercise on Office Workers NCT07763925 · NCT07763925 | Myopathies | Traitement symptomatique | Non applicable | COMPLETED | This study evaluated whether adding Pilates exercises to a desk-based exer… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| EXCEL — A Study to Check Liver Health in Boys With XLMTM, a Serious G… NCT06581146 · NCT06581146 | Myopathies | Traitement symptomatique · Thérapie génique | À vérifier | RECRUITING | XLMTM (X-linked myotubular myopathy) is a serious genetic muscle condition… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
Découverte scientifique
Recherches et trouvailles 0
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune trouvaille ne correspond aux filtres. | |||||||
Bibliographie
Publications 585
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Brain signatures of nociplastic pain: Fibromyalgia Index and descendi… Musculoskeletal Nociceptive Pain in Participants With Neuromuscular Disorders · PMID 40819274 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source Nociplastic pain is defined by altered nociceptive processing in the absence of clear peripheral damage or somatosensor… | Brain : a journal of neurology 2026-08-16 13:25:16 | Source |
| Neuropathic and Nociplastic Pain Profiles are Common in Adult Chronic… Musculoskeletal Nociceptive Pain in Participants With Neuromuscular Disorders · PMID 38627292 | Myopathies | Neuroprotection · Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Chronic nonbacterial osteitis (CNO) is a rare musculoskeletal disease causing chronic bone pain. It is known that chron… | Calcified tissue international 2026-08-16 13:25:16 | Source |
| Placebo-controlled Phase 2 Trial of Drisapersen for Duchenne Muscular… Drisapersen · PMID 30128316 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source This double-blind, randomized, placebo-controlled Phase 2 study (NCT01462292) assessed the 24-week efficacy, safety, to… | Annals of clinical and translational neurology 2026-08-16 13:25:16 | Source |
| Benefits of Telemonitoring of Pulmonary Function-3-Month Follow-Up of… AioCare spirometer · PMID 35160307 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source In patients with Duchenne Muscular Dystrophy (DMD), the respiratory system determines the quality and length of life; t… | Journal of clinical medicine 2026-08-16 13:25:15 | Source |
| Baseline neurochemical excitability and individual differences in mot… Non-invasive Neuromodulation · PMID 42263535 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Motor skill acquisition arises from complex interactions between inhibitory and excitatory neurotransmission in sensori… | Cortex; a journal devoted to the study of the nervous… 2026-08-16 13:25:08 | Source |
| Protocol for simultaneous non-invasive electrocardiogram and respirat… Kinesiology tape · PMID 42455681 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Here, we present a protocol for non-invasive simultaneous recording of electrocardiogram (ECG) and breathing in conscio… | STAR protocols 2026-08-16 13:25:08 | Source |
| Prospective Study of Video Hand Opening Time as a Quantitative Measur… SOUL-DM1 — Symptoms and Outcome Measures for Upper- Limb Function in Myotonic Dystrophy Type 1… | Myopathies | Ralentissement de la progression · Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Delayed grip relaxation is a common symptom of myotonic dystrophy type 1 (DM1), differing from other muscle diseases. P… | Neurology 2026-08-16 13:25:04 | Source |
| Case Report: Overlap of long QT syndrome and catecholaminergic polymo… Mexiletine · PMID 42558477 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Calmodulinopathy is a rare -related hereditary channelopathy presenting with long QT syndrome (LQTS), less commonly wit… | Frontiers in pediatrics 2026-08-16 13:25:02 | Source |
| HIF-Prolyl Hydroxylase Inhibitor Desidustat Increases Pyruvate Kinase… GSK1278863 · PMID 40192567 | Myopathies | Neuroprotection · Traitement symptomatique | Publication | PubMed | Voir la publication source Sickle cell anemia and beta-thalassemia are the major hemoglobinopathies associated with anemia. Bone marrow transplant… | Drug development research 2026-08-16 13:24:56 | Source |
| An investigation of a novel public health campaign to improve underst… Pain Science Education · PMID 42176372 | Myopathies | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Persistent pain is a high priority global public health issue. Misconceptions about persistent pain prevail in society… | Musculoskeletal science & practice 2026-08-16 13:24:52 | Source |
| Complex intervention including pain science education and patient-led… Pain Science Education · PMID 39739224 | Myopathies | Ralentissement de la progression · Traitement symptomatique | Publication | PubMed | Voir la publication source Up to 74% of breast cancer survivors (BCS) treated with aromatase inhibitor (AI) experience AI-induced musculoskeletal… | Journal of cancer survivorship : research and practice 2026-08-16 13:24:52 | Source |
| Diffusion-weighted magnetic resonance imaging as a promising techniqu… Magnetic Resonance Imaging and Ultrasound Comparison With Load Evaluation · PMID 42599582 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source A combination of morphological and functional imaging plays a crucial role for neuroendocrine tumors (NETs) management.… | Journal of endocrinological investigation 2026-08-16 13:24:52 | Source |
| Quantitative susceptibility mapping of the brain is associated with i… Magnetic Resonance Imaging and Ultrasound Comparison With Load Evaluation · PMID 41656561 | Myopathies | Immunomodulation | Publication | PubMed | Voir la publication source Accumulation of paramagnetic substances in brain tissue may constitute a feature of Alzheimer's disease (AD) associated… | Journal of cerebral blood flow and metabolism : offici… 2026-08-16 13:24:52 | Source |
| A Step-Up Underwater Endoscopic Mucosal Resection Strategy with Rescu… GenPHSat injection (Safety) · PMID 42111926 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Underwater endoscopic mucosal resection (UEMR) is an established treatment for non-pedunculated colorectal lesions, but… | DEN open 2026-08-16 13:24:48 | Source |
| Efficiency and Safety of Endoscopic Injection Sclerotherapy With Liga… GenPHSat injection (Safety) · PMID 42088735 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Endoscopic injection sclerotherapy with ligation (EISL) is a combined endoscopic treatment that involves endoscopic inj… | DEN open 2026-08-16 13:24:48 | Source |
| Real-time NMR analysis of glutamine metabolism for screening anti-can… Glutamine · PMID 42518517 | Myopathies | Ralentissement de la progression | Publication | PubMed | Voir la publication source Metabolic reprogramming is a substantial obstacle for anticancer drug screening, as targeted therapeutics often lose ef… | Magnetic resonance letters 2026-08-16 13:24:46 | Source |
| Transglutaminase 2 regulates innate immunity: mechanisms and therapeu… Glutamine · PMID 42053427 | Myopathies | Immunomodulation | Publication | PubMed | Voir la publication source Innate immunity constitutes the primary barrier against invading pathogens and plays a crucial role in coordinating the… | Oncoimmunology 2026-08-16 13:24:46 | Source |
| Creatine monohydrate for lean mass, strength, and bone density in pos… Creatine Monohydrate · PMID 42141930 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Menopause is accompanied by accelerated losses in muscle mass and strength and declining bone density. Whether creatine… | Journal of the International Society of Sports Nutriti… 2026-08-16 13:24:45 | Source |
| The emerging and evolving evidence supporting creatine as an ergogeni… Creatine Monohydrate · PMID 41870601 | Myopathies | Neuroprotection · Immunomodulation | Publication | PubMed | Voir la publication source Creatine is one of the most extensively studied ergogenic aids, with over three decades of research supporting its role… | Journal of the International Society of Sports Nutriti… 2026-08-16 13:24:45 | Source |
| Beyond rodents: A systematic review of antidepressant-like effects in… Desipramine · PMID 42538543 | Myopathies | Thérapie génique | Publication | PubMed | Voir la publication source The development of antidepressants has traditionally relied on vertebrate models. offers a promising alternative approa… | Alternatives to laboratory animals : ATLA 2026-08-16 13:24:34 | Source |
Exploration — prudence
Pistes exploratoires 6
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| N-PPG N-PPG — modulation métabolique cérébrale | Myopathies | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation métabolique et mitohormèse N-PPG est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être pertinents pour Myopat… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |
| Vecteur Ple389 (ADORA2A) MiniPromoter Ple389 — ciblage striatal | Myopathies | Thérapie génique | Hypothèse exploratoire | Rapprochement automatique non validé | Expression génique ciblée dans les neurones striataux Vecteur Ple389 (ADORA2A) est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être per… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |
| α-Amyrin α-Amyrin — protection mitochondriale | Myopathies | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Protection mitochondriale et modulation de la pathologie Tau α-Amyrin est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pour Myopa… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Myopathies | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation immunométabolique de la microglie 4-octyl itaconate et dérivés est étudié dans Sclérose latérale amyotrophique et documente plusieurs axes biologiques po… | Rapprochement Biomedical Watch · Sclérose latérale amy… | Détail |
| Thonningianin A Thonningianin A — neuroprotection anti-amyloïde | Myopathies | Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation du stress oxydatif et des protéines associées à Alzheimer Thonningianin A est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |
| Vutiglabridin Vutiglabridin — autophagie et PON2 | Myopathies | Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Activation de PON2 et stimulation de l’autophagie Vutiglabridin est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pour… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |