Vue transversale de la maladie
Myopathies
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
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1012 résultats correspondants
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dans le périmètre Myopathies
Niveau clinique
Études et traitements 421
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Track-DM — An Ambispective Natural History Study in Myotonic Dystroph… NCT07732439 · Track-DM — An Ambispective Natural History Study in Myotonic Dystrophy Patients… | Myopathies | Traitement symptomatique | À vérifier | NOT_YET_RECRUITING | This natural history observational study is being conducted to follow pati… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:36 | Détail |
| Vamorolone NCT06564974 · DMD-001 SUMMIT — Registry Study to Observe Long-term Safety of Vamorolone (AGAMR… | Myopathies | À vérifier | À vérifier | RECRUITING | The goal of this study is to collect additional information on the safety… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:36 | Détail |
| A Clinical Trial to Evaluate the Effects of Peptide Gummies on Marker… NCT07752381 · NCT07752381 | Myopathies | Immunomodulation | Non applicable | COMPLETED | This study will evaluate the effects of Parlay Recover peptide gummies (co… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:35 | Détail |
| Myofascial Release and Positional Release Techniques in Unilateral Tr… NCT07515352 · NCT07515352 | Myopathies | Ralentissement de la progression · Traitement symptomatique | Non applicable | COMPLETED | Unilateral trapezitis is characterized by upper trapezius myofascial pain… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:35 | Détail |
| Pimicotinib NCT07499362 · Study of Pimicotinib in Japanese Participants With Tenosynovial Giant Cell Tumor… | Myopathies | Immunomodulation | Phase 2 | RECRUITING | The primary purpose of this study is to assess the tolerability, pharmacok… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:35 | Détail |
| the — Eccentric vs Low-Load Blood Flow Restriction Training in Knee O… NCT07733518 · NCT07733518 | Myopathies | Ralentissement de la progression | Non applicable | RECRUITING | The aim of this randomized controlled trial is to find the effects of ecce… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:35 | Détail |
| Yoomi Physical Therapy Software NCT05815017 · YOOMI: Effect of Gamified Physical Therapy Exercise Software on Inpatient Mobili… | Myopathies | À vérifier | Non applicable | COMPLETED | Patients admitted to the hospital often develop functional impairments due… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:35 | Détail |
| 3 Year Follow up on ANO5 Patients NCT05206617 · NCT05206617 | Myopathies | Ralentissement de la progression | À vérifier | ACTIVE_NOT_RECRUITING | The aim of the study is to investigate progression in muscle affection in… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| ANO5 MRI — MRI-phenotyping of Patients With Pathogenic Anoctamin 5 Va… NCT05102799 · NCT05102799 | Myopathies | Thérapie génique | À vérifier | ACTIVE_NOT_RECRUITING | A large cohort of MRI scans from patients with pathogenic variants in the… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| Apitegromab NCT07435129 · Phase 2 Study Evaluating Apitegromab for the Treatment of FSHD | Myopathies | À vérifier | Phase 2 | RECRUITING | A randomized Phase 2 study to evaluate the efficacy and safety of apitegro… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| Botulinum toxin type A NCT07758322 · Efficacy of Focused Shock Wave Therapy Before and After Botulinum Toxin Injectio… | Myopathies | Traitement symptomatique | Non applicable | ACTIVE_NOT_RECRUITING | The main purpose of this study is to determine which is the best dose of a… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| Constant Current Stimulator NCT07715006 · Dorsal Root Electrical Stimulation in Children With Cerebral Palsy | Myopathies | Traitement symptomatique | Non applicable | RECRUITING | The goal of this clinical trial is to evaluate whether dorsal root electri… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| Conventional Stabilization Splints NCT07760428 · Comparison of Conventional,3D Printed and Novel Hybrid Stabilization Splints in… | Myopathies | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | Occlusal splint therapy is a well-established conservative approach for th… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| delpacibart zotadirsen NCT07250737 · Managed Access Program for Del-zota in Participants With DMD Mutations Amenable… | Myopathies | À vérifier | À vérifier | AVAILABLE | The purpose of this Managed Access Program is to allow access to delpaciba… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| DNA Methylation in PMR NCT07748195 · NCT07748195 | Myopathies | À vérifier | À vérifier | NOT_YET_RECRUITING | Polymyalgia Rheumatica (PMR) is treated with corticosteroids; however, lon… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| Dry Needling NCT07321483 · Reflex Therapy of Temporomandibular Dysfunctions | Myopathies | Traitement symptomatique | Non applicable | RECRUITING | This randomized clinical trial will aim to compare the effectiveness of dr… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| Dual-task cycling NCT07580365 · VirtualPark_Pediatric | Myopathies | À vérifier | Non applicable | RECRUITING | The goal of this clinical trial is to assess the effects of a dual-task, m… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| Effects of Curcumin-Piperine Supplementation in Fibromyalgia NCT07753018 · NCT07753018 | Myopathies | Neuroprotection · Immunomodulation · Traitement symptomatique | Phase 2 | NOT_YET_RECRUITING | The goal of this clinical trail is to evaluate the effectiveness and safet… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| Effects of Pilates and Desk-Based Exercise on Office Workers NCT07763925 · NCT07763925 | Myopathies | Traitement symptomatique | Non applicable | COMPLETED | This study evaluated whether adding Pilates exercises to a desk-based exer… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
| EXCEL — A Study to Check Liver Health in Boys With XLMTM, a Serious G… NCT06581146 · NCT06581146 | Myopathies | Traitement symptomatique · Thérapie génique | À vérifier | RECRUITING | XLMTM (X-linked myotubular myopathy) is a serious genetic muscle condition… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:34 | Détail |
Découverte scientifique
Recherches et trouvailles 0
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune trouvaille ne correspond aux filtres. | |||||||
Bibliographie
Publications 585
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Phase I/II Study of NGGT001 Gene Therapy for Bietti Crystalline Dystr… GenPHSat injection (Safety) · PMID 42437119 | Myopathies | Immunomodulation · Thérapie génique | Publication | PubMed | Voir la publication source To evaluate the safety and preliminary functional outcomes of NGGT001 gene therapy across dose cohorts in adults with B… | Ophthalmology science 2026-07-12 19:42:37 | Source |
| Unregulated Peptide Use in the Age of Biohacking: Digital Promotion,… GenPHSat injection (Safety) · PMID 42437212 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Unregulated peptide use is emerging as a digitally mediated public health concern. Although peptide-based medicines hav… | Cureus 2026-07-12 19:42:37 | Source |
| Autologous adipose-derived mesenchymal stromal cells for chronic trau… HB-adMSCs · PMID 42093626 | Myopathies | Immunomodulation · Traitement symptomatique · Thérapie cellulaire | Publication | PubMed | Voir la publication source Secondary injury from traumatic brain injury (TBI) leads to a chronic inflammatory process, neurodegeneration, and tiss… | Brain : a journal of neurology 2026-07-12 19:42:36 | Source |
| Evaluation of Multiple Intravenous Infusions of Autologous Adipose-De… HB-adMSCs · PMID 42137372 | Myopathies | Thérapie cellulaire | Publication | PubMed | Voir la publication source The purpose of this trial was to evaluate preliminary efficacy and safety of multiple intravenous infusions of autologo… | Parkinson's disease 2026-07-12 19:42:36 | Source |
| Genome-wide characterization of the Bcl-2-associated athanogene (BAG)… Glutamine · PMID 42435547 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Drought imposes one of the most damaging constraints on maize productivity, particularly during critical developmental… | Plant physiology and biochemistry : PPB 2026-07-12 19:42:36 | Source |
| How do media compositions, pretreatments, and genotypes affect haploi… Glutamine · PMID 42436375 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Currently, consumer demands are rapidly and continuously evolving, which accelerates the development and release of new… | BMC plant biology 2026-07-12 19:42:36 | Source |
| An 8-Year-Old Boy With Lateral Cutaneous Nerve Entrapment Syndrome: A… trigger point injection · PMID 42345584 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Résumé non disponible dans la base locale. | Pediatrics international : official journal of the Jap… 2026-07-12 19:42:33 | Source |
| Evaluation of Two Treatment Options in Myofascial Pain Transcutaneous… trigger point injection · PMID 42411416 | Myopathies | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Myofascial pain syndrome (MPS) is a familiar musculoskeletal disorder regarded as trigger points causing pain and funct… | Annals of African medicine 2026-07-12 19:42:33 | Source |
| Influence of Dystrophin Isoform Deficiency on Motor Development in Du… Outcome Measures in Duchenne Muscular Dystrophy: A Natural History Study · PMID 40552660 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source In Duchenne muscular dystrophy (DMD), lack of the shorter dystrophin isoforms Dp140 and Dp71 is associated with increas… | Annals of clinical and translational neurology 2026-07-12 19:42:33 | Source |
| Fulminant toxic epidermal necrolysis induced by pucotenlimab in a pat… IvIg · PMID 42434740 | Myopathies | Immunomodulation | Publication | PubMed | Voir la publication source This case report describes a fatal case of toxic epidermal necrolysis (TEN) in a 67-year-old man with stage IIIB lung a… | Frontiers in oncology 2026-07-12 19:42:28 | Source |
| Guillain-Barré Syndrome Following Dengue Infection: A Case Series wit… IvIg · PMID 42436651 | Myopathies | Neuroprotection · Ralentissement de la progression · Immunomodulation | Publication | PubMed | Voir la publication source Guillain-Barré syndrome (GBS) is a rare, immune-mediated disorder of the peripheral nerve and roots often triggered by… | Annals of neurosciences 2026-07-12 19:42:28 | Source |
| Nurse-led tobacco and areca-nut cessation interventions for oral pote… Behavioral Interventions for Controlling Oral Behaviors · PMID 42426750 | Myopathies | Ralentissement de la progression · Thérapie génique | Publication | PubMed | Voir la publication source Oral potentially malignant disorders (OPMDs), including oral submucous fibrosis, leukoplakia, lichen planus, and erythr… | BMC oral health 2026-07-12 19:42:28 | Source |
| Analyzing the Effect of Extracorporeal Shockwave Therapy after Botuli… Botulinum Toxin Type A for Injection · PMID 42427431 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source Spasticity is a frequent and disabling manifestation of multiple sclerosis (MS), characterized by increased muscle tone… | Advanced biomedical research 2026-07-12 19:42:26 | Source |
| Cellular Remodeling of Skeletal Muscle Following Botulinum Toxin A In… Botulinum Toxin Type A for Injection · PMID 42432377 | Myopathies | Thérapie génique | Publication | PubMed | Voir la publication source Botulinum toxin type A (BoNT) is widely used in aesthetic and reconstructive surgery, yet its effects on skeletal muscl… | Aesthetic plastic surgery 2026-07-12 19:42:26 | Source |
| A double-blinded randomized clinical trial: Topical Sahasthara extrac… Diclofenac 1% Topical · PMID 42382062 | Myopathies | Immunomodulation · Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Sahasthara (SHT), a traditional Thai herbal remedy used for anti-inflammatory and musculoskeletal disorders, lacks clin… | Journal of traditional and complementary medicine 2026-07-12 19:42:25 | Source |
| Baboon Syndrome Triggered by Diclofenac Potassium: A Case Report of S… Diclofenac 1% Topical · PMID 42405225 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source Baboon syndrome, also known as symmetrical drug-related intertriginous and flexural exanthema (SDRIFE), is a rare react… | Case reports in dermatology 2026-07-12 19:42:25 | Source |
| Risk factors of multi-drug-resistant tuberculosis among tuberculosis… COVID-19 Pandemic and Parents of Disabled Children · PMID 42426652 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Drug-resistant tuberculosis poses a significant threat to global TB control efforts, potentially reversing progress mad… | BMC infectious diseases 2026-07-12 19:42:15 | Source |
| A comparison of conservative versus surgical treatment in patients wi… test of walk · PMID 42436915 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source Patients with foot drop due to peroneal nerve entrapment are treated with either conservative or surgical approaches, y… | Brain & spine 2026-07-12 19:42:13 | Source |
| Multimodal Integration of Gait, Balance, and Infrared Thermography En… test of walk · PMID 42435928 | Myopathies | Traitement symptomatique | Publication | PubMed | Voir la publication source To investigate whether combining gait, balance, and infrared thermography improves discrimination between individuals w… | Archives of physical medicine and rehabilitation 2026-07-12 19:42:13 | Source |
| Global Research Trends in the Surgical Management of Spasticity: A Sy… baclofen · PMID 42424247 | Myopathies | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Surgical interventions remain a cornerstone in the multidisciplinary management of spasticity. While historically cente… | Stereotactic and functional neurosurgery 2026-07-12 19:42:08 | Source |
Exploration — prudence
Pistes exploratoires 6
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| N-PPG N-PPG — modulation métabolique cérébrale | Myopathies | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation métabolique et mitohormèse N-PPG est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être pertinents pour Myopat… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |
| Vecteur Ple389 (ADORA2A) MiniPromoter Ple389 — ciblage striatal | Myopathies | Thérapie génique | Hypothèse exploratoire | Rapprochement automatique non validé | Expression génique ciblée dans les neurones striataux Vecteur Ple389 (ADORA2A) est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être per… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |
| α-Amyrin α-Amyrin — protection mitochondriale | Myopathies | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Protection mitochondriale et modulation de la pathologie Tau α-Amyrin est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pour Myopa… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Myopathies | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation immunométabolique de la microglie 4-octyl itaconate et dérivés est étudié dans Sclérose latérale amyotrophique et documente plusieurs axes biologiques po… | Rapprochement Biomedical Watch · Sclérose latérale amy… | Détail |
| Thonningianin A Thonningianin A — neuroprotection anti-amyloïde | Myopathies | Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation du stress oxydatif et des protéines associées à Alzheimer Thonningianin A est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |
| Vutiglabridin Vutiglabridin — autophagie et PON2 | Myopathies | Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Activation de PON2 et stimulation de l’autophagie Vutiglabridin est étudié dans Maladie d’Alzheimer et documente plusieurs axes biologiques pouvant être pertinents pour… | Rapprochement Biomedical Watch · Maladie d’Alzheimer | Détail |