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Toutes les maladies
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Périmètre
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8666 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 4050
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Cabergoline 0.5 MG NCT07072910 · PROTECT — Cabergoline for Episodic Migraine | Migraine | À vérifier | Phase 2 | RECRUITING | The goal of this randomized, placebo-controlled, double-blind clinical tri… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:11 | Détail |
| Cerebri biofeedback NCT05616741 · BioCer — Home-based Biofeedback for the Prevention of Migraine | Migraine | À vérifier | Non applicable | COMPLETED | The goal of this clinical trial is to test an app-based biofeedback treatm… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:11 | Détail |
| INMEST-treatment NCT07279623 · A-MI-01 — Intra-Nasal Mechanical Stimulation (INMEST) as a Potential Preventativ… | Migraine | À vérifier | Non applicable | RECRUITING | This is a prospective, randomized, open-label, delayed-start clinical inve… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:11 | Détail |
| Rimegepant NCT05207865 · Safety and Tolerability Study of Daily Dosing Rimegepant in Episodic Migraine Pr… | Migraine | À vérifier | Phase 4 | COMPLETED | The purpose of this study is to evaluate safety and tolerability of BHV-30… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:11 | Détail |
| Rimegepant 75mg daily dosing NCT05217927 · Efficacy and Safety Study of Rimegepant in Episodic Migraine Prevention With Mul… | Migraine | À vérifier | Phase 4 | COMPLETED | The purpose of this study is to compare the efficacy and safety of daily a… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:11 | Détail |
| ViKEM — Vitamin K2 Supplementation in Adult Episodic Migraine NCT05943457 · NCT05943457 | Migraine | Ralentissement de la progression | Non applicable | RECRUITING | Migraine is a debilitating illness and a major cause of disability in the… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:11 | Détail |
| ACT for High Frequency Migraine; A Virtual Mindfulness Intervention NCT05003362 · NCT05003362 | Migraine | Traitement symptomatique | Non applicable | COMPLETED | Mindfulness Training specifically for pain to be offered to migraine patie… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:10 | Détail |
| Active drug for acute migraine treatment NCT06617832 · Trial Designs for Evaluating Migraine Treatment | Migraine | À vérifier | Non applicable | RECRUITING | The study aims to test interactions between drug and placebo-responses in… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:10 | Détail |
| Atogepant NCT05861427 · JPN PIVOTAL — Study of Oral Atogepant Tablets to Assess Change in Disease Activi… | Migraine | Traitement symptomatique | Phase 3 | COMPLETED | A migraine attack is a moderate or severe headache that usually occurs on… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:10 | Détail |
| Atorvastatin 40mg NCT06248671 · EStatinMig — Prophylactic Treatment With Atorvastatin for Episodic Migraine. | Migraine | À vérifier | Phase 2 | RECRUITING | The main objective of this study is to see whether the favorable preventat… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:10 | Détail |
| Bupivacaine HCl 0.5% Injectable Solution NCT05734625 · Efficacy of Nerve Blocks for Episodic Migraine | Migraine | Traitement symptomatique | Phase 2 | RECRUITING | The purpose of this study is to see how well blocking two to ten of the sc… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:10 | Détail |
| Chiropractic Care NCT06229834 · Chiropractic Care for Episodic Migraine | Migraine | Ralentissement de la progression | Non applicable | RECRUITING | Migraine, a chronic intermittent headache disorder, ranks in the top five… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:10 | Détail |
| Erenumab NCT04252742 · EMBRACE — Erenumab - Comprehensive Assessment of Efficacy in (High-Frequency) Ep… | Migraine | Traitement symptomatique | Phase 4 | COMPLETED | The primary objective of this study is to evaluate the treatment benefit o… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:10 | Détail |
| EXEMIG/01 — EXErcise in MIGraine NCT07508449 · NCT07508449 | Migraine | À vérifier | Non applicable | ACTIVE_NOT_RECRUITING | The study project aims to implement therapeutic patient education for migr… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:10 | Détail |
| Fremanezumab NCT04458857 · A Study to Test if Fremanezumab is Effective in Preventing Episodic Migraine in… | Migraine | À vérifier | Phase 3 | COMPLETED | The goal of this observational study is to compare, in real-world clinical… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:10 | Détail |
| Galcanezumab NCT03432286 · REBUILD-1 — A Study of Galcanezumab (LY2951742) in Participants 6 to 17 Years of… | Migraine | À vérifier | Phase 3 | ACTIVE_NOT_RECRUITING | The main purpose of this study is to evaluate the efficacy of the study dr… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:10 | Détail |
| Gou-Teng-San NCT07496034 · GTSEM — Efficacy of Gou-Teng-San (GTS) in Patients With Episodic Migraine | Migraine | Traitement symptomatique · Thérapie génique | Phase 3 | RECRUITING | The goal of this study is to learn whether Gou-Teng-San (GTS), a tradition… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:10 | Détail |
| MechSens_Migra — Migraine is Associated With Altered Mechanical Pain… NCT07559565 · MechSens_Migra — Migraine is Associated With Altered Mechanical Pain Sensitivity… | Migraine | Traitement symptomatique · Thérapie génique | À vérifier | NOT_YET_RECRUITING | Migraine is one of the most prevalent neurological disorders and is associ… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:10 | Détail |
| MIGRANE-YOGA — Online Hatha Yoga Program as an Add-On Therapy for Epi… NCT07694063 · NCT07694063 | Migraine | Ralentissement de la progression · Traitement symptomatique | Non applicable | RECRUITING | This randomized controlled trial aims to evaluate the effectiveness and fe… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:10 | Détail |
| Neurofeedback for Episodic Migraine NCT07661888 · NCT07661888 | Migraine | Ralentissement de la progression · Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | Background: Migraine is a highly prevalent neurological disorder and one o… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:10 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4595
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Effects of testosterone-augmented multimodal exercise intervention in… Whole-body Electrical Muscle Stimulation Exercise · PMID 41988780 | Myasthénie | À vérifier | Publication | PubMed | Voir la publication source Spinal cord injury (SCI) leads to profound muscle atrophy, aerobic deconditioning, and metabolic dysfunction. Exercise-… | The Journal of clinical endocrinology and metabolism 2026-09-20 04:37:05 | Source |
| Feasibility and acceptability of whole-body electromyostimulation in… Whole-body Electrical Muscle Stimulation Exercise · PMID 42464389 | Myasthénie | À vérifier | Publication | PubMed | Voir la publication source Evidence on the effectiveness of electromyostimulation (EMS) has been reported in pulmonary rehabilitation, but the ben… | Pilot and feasibility studies 2026-09-20 04:37:05 | Source |
| Vestibular contributions adapt to the balance strategies adopted duri… Whole-body Electrical Muscle Stimulation Exercise · PMID 42616645 | Myasthénie | À vérifier | Publication | PubMed | Voir la publication source Vestibular contributions during walking are not uniform, but vary with gait phase, muscle group, and balance demands. M… | Journal of neurophysiology 2026-09-20 04:37:05 | Source |
| Clinical efficacy of abdominal moxibustion at the Zhongji (CV3) in co… Yangyin Roujin Decoction · PMID 42015783 | Myopathies | Neuroprotection · Traitement symptomatique | Publication | PubMed | Voir la publication source To investigate the clinical effect of abdominal moxibustion at the Zhongji (CV3) combined with Yiqi Tonglin Yangyin dec… | Journal of traditional Chinese medicine = Chung i tsa… 2026-09-20 04:37:03 | Source |
| Yiqi Huoxue Yangyin Decoction Ameliorates Diabetic Nephropathy by Tar… Yangyin Roujin Decoction · PMID 42713045 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source This study aimed to investigate the protective effects and underlying mechanisms of Yiqi Huoxue Yangyin Decoction (YHY)… | Diabetes, metabolic syndrome and obesity : targets and… 2026-09-20 04:37:03 | Source |
| Yiqi Huoxue Yangyin Decoction attenuates diabetic nephropathy in mice… Yangyin Roujin Decoction · PMID 42016924 | Myopathies | Thérapie génique | Publication | PubMed | Voir la publication source Diabetic nephropathy (DN) is a major complication of diabetes with limited therapeutic options. Yiqi Huoxue Yangyin Dec… | Frontiers in pharmacology 2026-09-20 04:37:03 | Source |
| Barcoded oligonucleotide system (BOLT) for targeted organ delivery. Immunotherapy · PMID 42733790 | Cancer | À vérifier | Publication | PubMed | Voir la publication source The therapeutic potential of oligonucleotides (oligos) is limited by insufficient delivery to extrahepatic tissues. In… | Bioactive materials 2026-09-20 04:36:56 | Source |
| Dual metabolic checkpoint blockade a 3D-Printed metalloplatform remod… Immunotherapy · PMID 42724565 | Cancer | Immunomodulation | Publication | PubMed | Voir la publication source The immunosuppressive tumor microenvironment limits the efficacy of therapies that target metabolism. Here we show a st… | Bioactive materials 2026-09-20 04:36:56 | Source |
| Oligosaccharide adjuvant-deferred antigen endocytosis promotes cross-… Immunotherapy · PMID 42751513 | Cancer | Immunomodulation · Thérapie génique | Publication | PubMed | Voir la publication source Antigen cross-presentation by dendritic cells (DCs) is essential for inducing cytotoxic immune responses, which are cru… | Bioactive materials 2026-09-20 04:36:56 | Source |
| Feasibility and safety of early discharge after robot-assisted uro-on… Digital care pathway for hypertension · PMID 42671715 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source Early discharge after robot-assisted uro-oncologic surgery remains limited by concerns regarding patient safety and the… | Journal of robotic surgery 2026-09-20 04:36:49 | Source |
| HomeSafe: Postpartum Hypertensive Care Enabled by Electronic Health R… Digital care pathway for hypertension · PMID 41707683 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source The objective is to present stepwise refinements to , an Epic-tethered, population-health-coordinated postpartum pathwa… | American journal of perinatology 2026-09-20 04:36:49 | Source |
| Nutraceutical and functional food: efficacy against metabolic disorde… Digital care pathway for hypertension · PMID 42603698 | Hypertension artérielle | Neuroprotection · Immunomodulation | Publication | PubMed | Voir la publication source The growing global emphasis on health consciousness has significantly increased demand for traditional and complementar… | Journal of advanced research 2026-09-20 04:36:49 | Source |
| Community-engaged design of a virtual diabetes prevention program int… Asynchronous communication with nurse · PMID 42288862 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source The Diabetes Prevention Program (DPP) is an evidence-based approach to prevent Type 2 Diabetes (T2D), the leading cause… | BMC health services research 2026-09-20 04:36:48 | Source |
| Evolving Lung Cancer Navigator Practice Through Targeted Professional… Asynchronous communication with nurse · PMID 42463006 | Cancer | À vérifier | Publication | PubMed | Voir la publication source Lung cancer remains the leading cause of cancer deaths worldwide, and it has persistent disparities in detection, treat… | Chest 2026-09-20 04:36:48 | Source |
| Mass casualty training for prehospital and emergency providers in Kig… Asynchronous communication with nurse · PMID 42751142 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source A mass casualty incident (MCI) occurs when the number of patients exceeds available healthcare resources, placing signi… | African journal of emergency medicine : Revue africain… 2026-09-20 04:36:48 | Source |
| Innovating a Teach-Back Model for Community Health Workers Led Health… Health Literacy Project · PMID 40194526 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source From 2021 to 2023, the City of Albuquerque, the University of New Mexico (UNM) Office for Community Health, the UNM Hos… | Health literacy research and practice 2026-09-20 04:36:34 | Source |
| Carotid intima-media thickness may be an early biomarker for cardiova… Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy · PMID 41026111 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source To assess early signs of atherosclerosis following long-term treatment with the ketogenic diet therapy due to concerns… | Epilepsia open 2026-09-20 04:36:33 | Source |
| Impact of low-carbohydrate diet on health status: an umbrella review. Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy · PMID 39385794 | Cancer | À vérifier | Publication | PubMed | Voir la publication source The prevalence of diet-related non-communicable diseases has increased. A low-carbohydrate diet (LCDs) is one of the mo… | Frontiers in nutrition 2026-09-20 04:36:33 | Source |
| The effect of anti-seizure medications on lipid values in adults with… Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy · PMID 37244221 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source Certain anti-seizure medications (ASMs) adversely impact lipid values. Here, we explored the impact of ASMs on lipid va… | Epilepsy & behavior : E&B 2026-09-20 04:36:33 | Source |
| Possible role of locus coeruleus neuronal loss in age-related memory… The Role of the Locus Coeruleus in Age-related Distractibility · PMID 37694113 | Maladie d’Alzheimer | Immunomodulation | Publication | PubMed | Voir la publication source Aging is associated with a decline in cognitive abilities, including memory and attention. It is generally accepted tha… | Frontiers in neuroscience 2026-09-20 04:36:30 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||