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Toutes les maladies
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Périmètre
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8666 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 4050
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| FAST — Molecular Phenotyping of Migraine Patients According to Sex an… NCT06674772 · NCT06674772 | Migraine | À vérifier | À vérifier | RECRUITING | Patients will be asked to visit the study center 2 times, the first time f… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:15 | Détail |
| Fu's Subcutaneous Needling NCT07068815 · Efficacy and Mechanism of Fu's Subcutaneous Needling Treatment for Migraine With… | Migraine | Traitement symptomatique | Phase 1 | NOT_YET_RECRUITING | This study aimed to compare the analgesic efficacy and quality-of-life imp… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:15 | Détail |
| Levcromakalim NCT05211050 · SLIM — Effect of Sumatriptan on Levcromakalim-Induced Symptoms in Individuals Wi… | Migraine | Traitement symptomatique | Non applicable | COMPLETED | This study aims to explore the effect of Ivabradine on Levcromakalim-induc… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:15 | Détail |
| Myotensive Extraocular Muscle Techniques Added to Manual Therapy for… NCT07254598 · NCT07254598 | Migraine | Ralentissement de la progression · Traitement symptomatique · Thérapie génique | Non applicable | NOT_YET_RECRUITING | Migraine without aura is a highly prevalent and disabling primary headache… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:15 | Détail |
| Substance P NCT06959004 · Substance P-Induced Migraine Attacks Without Aura | Migraine | À vérifier | Non applicable | RECRUITING | Substance P is a neuropeptide implicated in the pathogenesis of headache.… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:15 | Détail |
| Almotriptan 12.5 Mg Oral Tablet NCT05214001 · ATOM — Evaluation of the Efficacy of Almotriptan and Ubrogepant for the Acute Tr… | Migraine | Traitement symptomatique | Phase 4 | TERMINATED | In a real-world population of adults with migraine, the investigators woul… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:14 | Détail |
| Be-Home-Kids — Feasibility and Effectiveness of Home-behavioral Progr… NCT04604977 · NCT04604977 | Migraine | Traitement symptomatique | Non applicable | COMPLETED | Chronic Migraine and Migraine without aura at high frequency are disabling… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:14 | Détail |
| Caffeine (200 mg) NCT07022496 · Assessment of Oral Caffeine Intake in Changing the Severity of Acute Migraine At… | Migraine | À vérifier | Phase 4 | RECRUITING | Caffeine extracted from green tea to abort acute attack of Migraine À vérifier | ClinicalTrials.gov 2026-08-13 14:17:14 | Détail |
| HELP-VM — Healthy Living Partnerships for Veterans With Migraine NCT04373330 · NCT04373330 | Migraine | Traitement symptomatique | Non applicable | WITHDRAWN | This pilot study, modeled upon the successful and empirically validated HE… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:14 | Détail |
| Partial Rebreathing Device NCT05546385 · PAREMA1 — PArtial REbreathing for Migraine With Aura 1 | Migraine | À vérifier | Non applicable | TERMINATED | A prospective, multi-centre, randomized, double-blind, sham-controlled, pa… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:14 | Détail |
| Active drug for chronic migraine treatment. NCT07071506 · New Methods for Evaluating Preventive Migraine Treatment | Migraine | À vérifier | Non applicable | RECRUITING | The study aims to test interactions between drug and placebo-responses in… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Actual device PFO closure NCT04100135 · RELIEF — GORE® CARDIOFORM Septal Occluder Migraine Clinical Study | Migraine | À vérifier | Non applicable | TERMINATED | Multi-center, prospective, randomized, placebo- and sham-controlled study… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| ACU-BRAIN — Brain Connectome for Acupuncture-treated Migraine Patients NCT04157192 · NCT04157192 | Migraine | Traitement symptomatique | Non applicable | COMPLETED | Acupuncture has been a means of treating headaches and migraine since 2002… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| ACUPMIGRAINE — The Impact of Acupuncture on Biomarkers of Brain Injur… NCT07292506 · NCT07292506 | Migraine | Immunomodulation · Traitement symptomatique | Non applicable | ACTIVE_NOT_RECRUITING | Migraine is more than just a headache-it can involve changes in the brain… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Amiloride NCT04063540 · APAM — Acid-Sensing Ion Channel and Migraine Disease Proof of Concept Study on t… | Migraine | À vérifier | Phase 2 | RECRUITING | Recent data suggest involvement of Acid-Sensing Ion Channel channels in th… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| App-Based Migraine Treatment: The Health enSuite Study NCT06797076 · NCT06797076 | Migraine | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | Health enSuite is a suite of applications designed by our research team at… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Atogepant 60 mg NCT06414044 · STAR — Italian Real-life obServational Study on the effecTiveness, sAfety and To… | Migraine | À vérifier | À vérifier | ACTIVE_NOT_RECRUITING | This goal of this study is to compare three medications used for migraine… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| BE WELL With Migraine: Brain Education and WELLness With Migraine NCT05987592 · NCT05987592 | Migraine | À vérifier | Non applicable | RECRUITING | The goal of this randomized clinical trial is to evaluate two different no… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Biodegradable occluder NCT06203873 · BioMetal — A Comparison of Biodegradable and Metal Occluders in Patients With PF… | Migraine | Traitement symptomatique | Non applicable | RECRUITING | Migraine is one of the most common chronic neurological disorders, posing… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Calcitonin-gene related peptide (CGRP) NCT07021859 · Induction of Migraine Attacks With Aura Using Calcitonin Gene-Related Peptide | Migraine | À vérifier | Non applicable | RECRUITING | Calcitonin gene-related peptide (CGRP) is a key neuropeptide in migraine p… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4595
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Effects of testosterone-augmented multimodal exercise intervention in… Whole-body Electrical Muscle Stimulation Exercise · PMID 41988780 | Myasthénie | À vérifier | Publication | PubMed | Voir la publication source Spinal cord injury (SCI) leads to profound muscle atrophy, aerobic deconditioning, and metabolic dysfunction. Exercise-… | The Journal of clinical endocrinology and metabolism 2026-09-20 04:37:05 | Source |
| Feasibility and acceptability of whole-body electromyostimulation in… Whole-body Electrical Muscle Stimulation Exercise · PMID 42464389 | Myasthénie | À vérifier | Publication | PubMed | Voir la publication source Evidence on the effectiveness of electromyostimulation (EMS) has been reported in pulmonary rehabilitation, but the ben… | Pilot and feasibility studies 2026-09-20 04:37:05 | Source |
| Vestibular contributions adapt to the balance strategies adopted duri… Whole-body Electrical Muscle Stimulation Exercise · PMID 42616645 | Myasthénie | À vérifier | Publication | PubMed | Voir la publication source Vestibular contributions during walking are not uniform, but vary with gait phase, muscle group, and balance demands. M… | Journal of neurophysiology 2026-09-20 04:37:05 | Source |
| Clinical efficacy of abdominal moxibustion at the Zhongji (CV3) in co… Yangyin Roujin Decoction · PMID 42015783 | Myopathies | Neuroprotection · Traitement symptomatique | Publication | PubMed | Voir la publication source To investigate the clinical effect of abdominal moxibustion at the Zhongji (CV3) combined with Yiqi Tonglin Yangyin dec… | Journal of traditional Chinese medicine = Chung i tsa… 2026-09-20 04:37:03 | Source |
| Yiqi Huoxue Yangyin Decoction Ameliorates Diabetic Nephropathy by Tar… Yangyin Roujin Decoction · PMID 42713045 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source This study aimed to investigate the protective effects and underlying mechanisms of Yiqi Huoxue Yangyin Decoction (YHY)… | Diabetes, metabolic syndrome and obesity : targets and… 2026-09-20 04:37:03 | Source |
| Yiqi Huoxue Yangyin Decoction attenuates diabetic nephropathy in mice… Yangyin Roujin Decoction · PMID 42016924 | Myopathies | Thérapie génique | Publication | PubMed | Voir la publication source Diabetic nephropathy (DN) is a major complication of diabetes with limited therapeutic options. Yiqi Huoxue Yangyin Dec… | Frontiers in pharmacology 2026-09-20 04:37:03 | Source |
| Barcoded oligonucleotide system (BOLT) for targeted organ delivery. Immunotherapy · PMID 42733790 | Cancer | À vérifier | Publication | PubMed | Voir la publication source The therapeutic potential of oligonucleotides (oligos) is limited by insufficient delivery to extrahepatic tissues. In… | Bioactive materials 2026-09-20 04:36:56 | Source |
| Dual metabolic checkpoint blockade a 3D-Printed metalloplatform remod… Immunotherapy · PMID 42724565 | Cancer | Immunomodulation | Publication | PubMed | Voir la publication source The immunosuppressive tumor microenvironment limits the efficacy of therapies that target metabolism. Here we show a st… | Bioactive materials 2026-09-20 04:36:56 | Source |
| Oligosaccharide adjuvant-deferred antigen endocytosis promotes cross-… Immunotherapy · PMID 42751513 | Cancer | Immunomodulation · Thérapie génique | Publication | PubMed | Voir la publication source Antigen cross-presentation by dendritic cells (DCs) is essential for inducing cytotoxic immune responses, which are cru… | Bioactive materials 2026-09-20 04:36:56 | Source |
| Feasibility and safety of early discharge after robot-assisted uro-on… Digital care pathway for hypertension · PMID 42671715 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source Early discharge after robot-assisted uro-oncologic surgery remains limited by concerns regarding patient safety and the… | Journal of robotic surgery 2026-09-20 04:36:49 | Source |
| HomeSafe: Postpartum Hypertensive Care Enabled by Electronic Health R… Digital care pathway for hypertension · PMID 41707683 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source The objective is to present stepwise refinements to , an Epic-tethered, population-health-coordinated postpartum pathwa… | American journal of perinatology 2026-09-20 04:36:49 | Source |
| Nutraceutical and functional food: efficacy against metabolic disorde… Digital care pathway for hypertension · PMID 42603698 | Hypertension artérielle | Neuroprotection · Immunomodulation | Publication | PubMed | Voir la publication source The growing global emphasis on health consciousness has significantly increased demand for traditional and complementar… | Journal of advanced research 2026-09-20 04:36:49 | Source |
| Community-engaged design of a virtual diabetes prevention program int… Asynchronous communication with nurse · PMID 42288862 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source The Diabetes Prevention Program (DPP) is an evidence-based approach to prevent Type 2 Diabetes (T2D), the leading cause… | BMC health services research 2026-09-20 04:36:48 | Source |
| Evolving Lung Cancer Navigator Practice Through Targeted Professional… Asynchronous communication with nurse · PMID 42463006 | Cancer | À vérifier | Publication | PubMed | Voir la publication source Lung cancer remains the leading cause of cancer deaths worldwide, and it has persistent disparities in detection, treat… | Chest 2026-09-20 04:36:48 | Source |
| Mass casualty training for prehospital and emergency providers in Kig… Asynchronous communication with nurse · PMID 42751142 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source A mass casualty incident (MCI) occurs when the number of patients exceeds available healthcare resources, placing signi… | African journal of emergency medicine : Revue africain… 2026-09-20 04:36:48 | Source |
| Innovating a Teach-Back Model for Community Health Workers Led Health… Health Literacy Project · PMID 40194526 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source From 2021 to 2023, the City of Albuquerque, the University of New Mexico (UNM) Office for Community Health, the UNM Hos… | Health literacy research and practice 2026-09-20 04:36:34 | Source |
| Carotid intima-media thickness may be an early biomarker for cardiova… Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy · PMID 41026111 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source To assess early signs of atherosclerosis following long-term treatment with the ketogenic diet therapy due to concerns… | Epilepsia open 2026-09-20 04:36:33 | Source |
| Impact of low-carbohydrate diet on health status: an umbrella review. Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy · PMID 39385794 | Cancer | À vérifier | Publication | PubMed | Voir la publication source The prevalence of diet-related non-communicable diseases has increased. A low-carbohydrate diet (LCDs) is one of the mo… | Frontiers in nutrition 2026-09-20 04:36:33 | Source |
| The effect of anti-seizure medications on lipid values in adults with… Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy · PMID 37244221 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source Certain anti-seizure medications (ASMs) adversely impact lipid values. Here, we explored the impact of ASMs on lipid va… | Epilepsy & behavior : E&B 2026-09-20 04:36:33 | Source |
| Possible role of locus coeruleus neuronal loss in age-related memory… The Role of the Locus Coeruleus in Age-related Distractibility · PMID 37694113 | Maladie d’Alzheimer | Immunomodulation | Publication | PubMed | Voir la publication source Aging is associated with a decline in cognitive abilities, including memory and attention. It is generally accepted tha… | Frontiers in neuroscience 2026-09-20 04:36:30 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||