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Migraine
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
Périmètre
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1236 résultats correspondants
· 45 visibles sur cette page
dans le périmètre Migraine
Niveau clinique
Études et traitements 570
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| ReMMi-D Digital Therapeutic NCT05853900 · ReMMi-D — Study of Two Digital Therapeutics for the Prevention of Episodic Migra… | Migraine | À vérifier | Non applicable | COMPLETED | Randomized study of two digital therapeutics for the prevention of episodi… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:12 | Détail |
| SPHERA_WP2 — Searching for Novel Therapeutic Approaches in Migraine P… NCT06562400 · NCT06562400 | Migraine | À vérifier | À vérifier | RECRUITING | Primary working hypothesis is that NON-responders to mAbs bear a dysfuncti… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:12 | Détail |
| 5% lidocaine/5 mg/ml 0.02% estradiol compound cream NCT03844412 · Vestibulodynia: Understanding Pathophysiology and Determining Appropriate Treatm… | Migraine | Traitement symptomatique · Thérapie génique | Phase 2 | COMPLETED | Vestibulodynia (VBD) is a complex chronic vulvar pain condition that impai… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:09 | Détail |
| Bupivacaine NCT07497646 · GONBLOCK-RCT — Repeated Bilateral Greater Occipital Nerve Blockade in Chronic Mi… | Migraine | Ralentissement de la progression · Thérapie génique | Non applicable | COMPLETED | This multicenter, randomized, double-blind, placebo-controlled clinical tr… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:09 | Détail |
| CBD 100 mg OD NCT03972124 · Cannabis for the Prophylactic Treatment of Migraine | Migraine | À vérifier | Phase 2 | RECRUITING | This study will evaluate the efficacy and safety of cannabis for the treat… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:09 | Détail |
| Emgality 120 MG in 1 ML Prefilled Syringe NCT04271202 · Novel Insight Into Migraine Pathophysiolgy and Galcanezumab Mechanisms of Action | Migraine | À vérifier | Phase 4 | COMPLETED | The purpose of this study is to understand better the mechanisms of action… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:09 | Détail |
| Greater occiptal nerve block NCT07512219 · Comparison Between Greater Occipital Nerve Block and Pulsed Radiofrequency in th… | Migraine | À vérifier | Non applicable | NOT_YET_RECRUITING | Comparative Study of Greater Occipital Nerve Block and Pulsed Radiofrequen… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:09 | Détail |
| HEAD-TMD — Pericranial and General Sensitivity in Patients With Prima… NCT07514208 · NCT07514208 | Migraine | Ralentissement de la progression · Traitement symptomatique | À vérifier | ENROLLING_BY_INVITATION | Primary headaches such as migraine and tension type headache are among the… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:09 | Détail |
| Mind Body Intervention for Chronic Migraine Headaches NCT06690060 · NCT06690060 | Migraine | À vérifier | Non applicable | RECRUITING | The goal of this exploratory study is to test a mind-body interventional a… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:09 | Détail |
| Neurostimulator NCT06167655 · A PIVOTAL STUDY EVALUATING SAFETY AND EFFICACY OF THE SHIRATRONICS MIGRAINE THER… | Migraine | À vérifier | Non applicable | ACTIVE_NOT_RECRUITING | The purpose of this pivotal clinical study is to evaluate the safety and e… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:09 | Détail |
| Non-Invasive Brain Stimulation as Add-on Treatment in Chronic Migrain… NCT07442916 · NCT07442916 | Migraine | À vérifier | Non applicable | COMPLETED | This randomized, double-blind, sham-controlled clinical trial aims to eval… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:09 | Détail |
| Nurse Intervention Trial NCT06200480 · NCT06200480 | Migraine | À vérifier | Non applicable | TERMINATED | This randomized open-label prospective study focus on headache patients in… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:09 | Détail |
| occipital nerve stimulator NCT06022848 · Quantitative Sensory Testing and Occipital Nerve Stimulator | Migraine | Traitement symptomatique | Non applicable | COMPLETED | The primary aim of this study is to assess the reversibility of a range of… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:09 | Détail |
| OnabotulinumtoxinA NCT07535723 · Botulinum Toxin and/or Greater Occipital Nerve Block for Patients With Chronic M… | Migraine | À vérifier | Non applicable | NOT_YET_RECRUITING | Chronic migraine is a debilitating neurological disorder that significantl… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:09 | Détail |
| onabotulinumtoxinA prophylaxis with Lidocaine NCT07571889 · Topical Intranasal Anesthetic Block for Reducing the Pain of Botulinum Toxin Inj… | Migraine | Traitement symptomatique | Non applicable | RECRUITING | People find the injections used in onabotulinumtoxinA (Botox®) uncomfortab… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:09 | Détail |
| SOMATIN — Multimodal Therapy for Somatosensory Tinnitus NCT07468318 · NCT07468318 | Migraine | À vérifier | Non applicable | NOT_YET_RECRUITING | Tinnitus (ringing or buzzing in the ears) affects approximately 10-15% of… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:09 | Détail |
| Study on 30 Outpatients With Chronic Migraine Treated With Well-Being… NCT03404336 · NCT03404336 | Migraine | Ralentissement de la progression | Non applicable | RECRUITING | Chronic migraine is a disabling type of migraine and is often resistant to… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:09 | Détail |
| Vibrotactile Stimulation NCT04069572 · Vibratory Stimulation for the Treatment of Chronic Pain | Migraine | Traitement symptomatique | Non applicable | SUSPENDED | The purpose of this study is to perform a first in man study with VCR stim… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:09 | Détail |
| Virtual Reality NCT07374640 · Virtual Reality and Biofeedback for Adolescents With Chronic Dizziness | Migraine | Traitement symptomatique | Phase 1 | NOT_YET_RECRUITING | Both persistent postural-perceptual dizziness (PPPD) and vestibular migrai… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:09 | Détail |
| Efficacy of Smartphone Based Digital Application in Improving Headach… NCT04984720 · NCT04984720 | Migraine | Traitement symptomatique | Non applicable | COMPLETED | Migraine is a common headache disorder and affects 1 in 5 adults during th… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:08 | Détail |
Découverte scientifique
Recherches et trouvailles 0
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune trouvaille ne correspond aux filtres. | |||||||
Bibliographie
Publications 661
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Amylin Coexisting With Peptide YY (PYY) and Amylin/PYY Cells Correspo… Amylin · PMID 42559671 | Migraine | Immunomodulation | Publication | PubMed | Voir la publication source The distribution of amylin-like substances was investigated by immunohistochemistry in the pancreas of the Japanese eel… | Anatomia, histologia, embryologia 2026-08-08 00:58:52 | Source |
| Acute effects of "exercise snacks" on postprandial glucose and insuli… Endothelin-1 · PMID 42558375 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source Exercise snacks-short, frequent bouts of physical activity that interrupt prolonged sitting-improve postprandial glucos… | Frontiers in endocrinology 2026-08-08 00:58:51 | Source |
| Hypoxemia with atelectasis during clazosentan therapy after subarachn… Endothelin-1 · PMID 42558750 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Clazosentan, a selective endothelin-A (ET-A) receptor antagonist, is used to prevent cerebral vasospasm after aneurysma… | Nagoya journal of medical science 2026-08-08 00:58:51 | Source |
| Emerging Neurovascular Interventions for the Prevention of Cerebral V… Cilostazol · PMID 42540693 | Migraine | Neuroprotection · Immunomodulation | Publication | PubMed | Voir la publication source Aneurysmal subarachnoid hemorrhage remains a major cause of neurological morbidity and mortality, with delayed cerebral… | Cureus 2026-08-08 00:58:50 | Source |
| Isosorbide Mononitrate/Cilostazol for Lacunar Cerebral Small Vessel D… Cilostazol · PMID 42535538 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Lacunar stroke can cause cognitive decline and dependency. The LACI-2 (Lacunar Intervention Trial-2) trial showed that… | Journal of the American Heart Association 2026-08-08 00:58:50 | Source |
| Twelve-months prospective real-world assessment of effectiveness and… Eptinezumab 100 mg or Eptinezumab 300 mg administered intravenously in 100 mL saline solution… | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Randomized clinical trials have demonstrated the efficacy and safety of eptinezumab. The aim of this study was to evalu… | The journal of headache and pain 2026-08-08 00:58:47 | Source |
| Targeting G-coupled GPCRs to inhibit nociceptors: Insights from the s… Triptan · PMID 42532046 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Pain perception is initiated upon activation of nociceptors of the dorsal root ganglia (DRG) and trigeminal ganglia. We… | Cell reports. Medicine 2026-08-08 00:58:45 | Source |
| Gastrointestinal Ascariasis: Unusual Presentation in 2 Cases. Non-steroidal anti-inflammatory drug (NSAID) · PMID 42540124 | Migraine | Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Ascariasis is a helminthic infection caused by the nematode and remains the most prevalent helminth infection worldwide… | Nigerian medical journal : journal of the Nigeria Medi… 2026-08-08 00:58:44 | Source |
| Impact of semaglutide introduction on the use of triptans: an interru… Triptan · PMID 42557547 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Emerging evidence suggests that glucagon-like peptide-1 receptor agonist (GLP-1RA) may be associated with reduced migra… | The journal of headache and pain 2026-08-08 00:58:44 | Source |
| In Vitro Evaluation of Lornoxicam Liquitablets: Permeability, Anti-In… Non-steroidal anti-inflammatory drug (NSAID) · PMID 42546887 | Migraine | Immunomodulation · Thérapie génique | Publication | PubMed | Voir la publication source Lornoxicam (LXM) is a potent non-steroidal anti-inflammatory drug (NSAID), characterised by low aqueous solubility, whi… | European journal of pharmaceutical sciences : official… 2026-08-08 00:58:44 | Source |
| Botulinum toxin in peripheral facial paralysis: systematic review and… Onabotulinum toxin A · PMID 42517166 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Peripheral facial paralysis (PFP) causes both static and dynamic facial dysfunctions, leading to synkinesis, hypertonia… | European journal of physical and rehabilitation medici… 2026-08-08 00:58:43 | Source |
| Repeated botulinum toxin injections for neurogenic thoracic outlet sy… Onabotulinum toxin A · PMID 42550976 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Neurogenic thoracic outlet syndrome (nTOS) is a condition caused by compression of the brachial plexus in the thoracic… | Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = T… 2026-08-08 00:58:43 | Source |
| Projected budget impact of pharmacotherapy scenarios for obesity and… topiramate · PMID 42565180 | Migraine | À vérifier | Publication | PubMed | Voir la publication source The increasing prevalence of obesity is generating demand for chronic pharmacologic treatment, but Latin American evide… | Obesity pillars 2026-08-08 00:58:42 | Source |
| Weight mitigation and tolerability of adjunctive topiramate in acute… topiramate · PMID 42558898 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Psychotropic medications are often associated with significant and rapid weight gain in pediatric populations, especial… | Frontiers in psychiatry 2026-08-08 00:58:42 | Source |
| Feasibility of Emotional Awareness and Expression Therapy Adapted for… Exploring Clinical Trial Experiences of Patients With Migraine · PMID 41742651 | Migraine | Ralentissement de la progression | Publication | PubMed | Voir la publication source Chronic headache, including migraine, is often associated with psychiatric conditions and adverse childhood experiences… | The Canadian journal of neurological sciences. Le jour… 2026-08-08 00:58:38 | Source |
| Physical Therapy Targeting Autonomic and Dura Mater Function: SPINEPA… Exploring Clinical Trial Experiences of Patients With Migraine · PMID 41324433 | Migraine | Ralentissement de la progression · Traitement symptomatique | Publication | PubMed | Voir la publication source Persistent post-traumatic headache (PPTH) or concussion is a significant United States military problem, and pharmacolo… | Physical therapy 2026-08-08 00:58:38 | Source |
| Efficacy and safety of gepants in migraine management: a narrative re… Rimegepant 75 MG · PMID 42548099 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Gepants, oral antagonists of the calcitonin gene-related peptide (CGRP) receptor, represent a new therapeutic class in… | Journal of oral & facial pain and headache 2026-08-08 00:58:35 | Source |
| Diagnostic value of shear wave elastography in assessing the effectiv… Botulinum toxin type A · PMID 42566101 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source Complex W3 ventral hernias with loss of domain (LOD) pose challenges in abdominal wall reconstruction due to pathologic… | Hernia : the journal of hernias and abdominal wall sur… 2026-08-08 00:58:34 | Source |
| [Treatment persistence and adherence with botulinum toxin type A and… Botulinum toxin type A · PMID 42565401 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source To compare the treatment persistence and adherence with botulinum toxin type A (Relatox; BTA) and monoclonal antibodies… | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 2026-08-08 00:58:34 | Source |
| Multi-organ AI endophenotypes chart the heterogeneity of brain, eye a… Digoxin · PMID 42559122 | Migraine | Ralentissement de la progression · Thérapie génique | Publication | PubMed | Voir la publication source Disease heterogeneity and commonality pose significant challenges to precision medicine, as traditional approaches freq… | Nature. Mental health 2026-08-08 00:57:54 | Source |
Exploration — prudence
Pistes exploratoires 5
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Bavisant BRAVEinMS — Bavisant | Migraine | Remyélinisation · Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Antagonisme du récepteur H3 de l’histamine Bavisant est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migra… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| Tol-MP Tol-MP — tolérance immunitaire spécifique de la myéline | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Microparticules biodégradables chargées en rapamycine et fonctionnalisées… Tol-MP est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migrain… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| SetPoint System SetPoint System — SetPoint Medical | Migraine | Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | re ApplicationsPublicationsCompanyCareersNewsGet startedGet startedNewsThe… SetPoint System est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation immunométabolique de la microglie 4-octyl itaconate et dérivés est étudié dans Sclérose latérale amyotrophique et documente plusieurs axes biologiques po… | Rapprochement Biomedical Watch · Sclérose latérale amy… | Détail |
| N-PPG N-PPG — modulation métabolique cérébrale | Migraine | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation métabolique et mitohormèse N-PPG est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être pertinents pour Migrai… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |