Vue transversale de la maladie
Migraine
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
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1236 résultats correspondants
· 45 visibles sur cette page
dans le périmètre Migraine
Niveau clinique
Études et traitements 570
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| ReMMi-D Digital Therapeutic NCT05853900 · ReMMi-D — Study of Two Digital Therapeutics for the Prevention of Episodic Migra… | Migraine | À vérifier | Non applicable | COMPLETED | Randomized study of two digital therapeutics for the prevention of episodi… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:12 | Détail |
| SPHERA_WP2 — Searching for Novel Therapeutic Approaches in Migraine P… NCT06562400 · NCT06562400 | Migraine | À vérifier | À vérifier | RECRUITING | Primary working hypothesis is that NON-responders to mAbs bear a dysfuncti… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:12 | Détail |
| 5% lidocaine/5 mg/ml 0.02% estradiol compound cream NCT03844412 · Vestibulodynia: Understanding Pathophysiology and Determining Appropriate Treatm… | Migraine | Traitement symptomatique · Thérapie génique | Phase 2 | COMPLETED | Vestibulodynia (VBD) is a complex chronic vulvar pain condition that impai… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:09 | Détail |
| Bupivacaine NCT07497646 · GONBLOCK-RCT — Repeated Bilateral Greater Occipital Nerve Blockade in Chronic Mi… | Migraine | Ralentissement de la progression · Thérapie génique | Non applicable | COMPLETED | This multicenter, randomized, double-blind, placebo-controlled clinical tr… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:09 | Détail |
| CBD 100 mg OD NCT03972124 · Cannabis for the Prophylactic Treatment of Migraine | Migraine | À vérifier | Phase 2 | RECRUITING | This study will evaluate the efficacy and safety of cannabis for the treat… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:09 | Détail |
| Emgality 120 MG in 1 ML Prefilled Syringe NCT04271202 · Novel Insight Into Migraine Pathophysiolgy and Galcanezumab Mechanisms of Action | Migraine | À vérifier | Phase 4 | COMPLETED | The purpose of this study is to understand better the mechanisms of action… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:09 | Détail |
| Greater occiptal nerve block NCT07512219 · Comparison Between Greater Occipital Nerve Block and Pulsed Radiofrequency in th… | Migraine | À vérifier | Non applicable | NOT_YET_RECRUITING | Comparative Study of Greater Occipital Nerve Block and Pulsed Radiofrequen… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:09 | Détail |
| HEAD-TMD — Pericranial and General Sensitivity in Patients With Prima… NCT07514208 · NCT07514208 | Migraine | Ralentissement de la progression · Traitement symptomatique | À vérifier | ENROLLING_BY_INVITATION | Primary headaches such as migraine and tension type headache are among the… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:09 | Détail |
| Mind Body Intervention for Chronic Migraine Headaches NCT06690060 · NCT06690060 | Migraine | À vérifier | Non applicable | RECRUITING | The goal of this exploratory study is to test a mind-body interventional a… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:09 | Détail |
| Neurostimulator NCT06167655 · A PIVOTAL STUDY EVALUATING SAFETY AND EFFICACY OF THE SHIRATRONICS MIGRAINE THER… | Migraine | À vérifier | Non applicable | ACTIVE_NOT_RECRUITING | The purpose of this pivotal clinical study is to evaluate the safety and e… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:09 | Détail |
| Non-Invasive Brain Stimulation as Add-on Treatment in Chronic Migrain… NCT07442916 · NCT07442916 | Migraine | À vérifier | Non applicable | COMPLETED | This randomized, double-blind, sham-controlled clinical trial aims to eval… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:09 | Détail |
| Nurse Intervention Trial NCT06200480 · NCT06200480 | Migraine | À vérifier | Non applicable | TERMINATED | This randomized open-label prospective study focus on headache patients in… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:09 | Détail |
| occipital nerve stimulator NCT06022848 · Quantitative Sensory Testing and Occipital Nerve Stimulator | Migraine | Traitement symptomatique | Non applicable | COMPLETED | The primary aim of this study is to assess the reversibility of a range of… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:09 | Détail |
| OnabotulinumtoxinA NCT07535723 · Botulinum Toxin and/or Greater Occipital Nerve Block for Patients With Chronic M… | Migraine | À vérifier | Non applicable | NOT_YET_RECRUITING | Chronic migraine is a debilitating neurological disorder that significantl… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:09 | Détail |
| onabotulinumtoxinA prophylaxis with Lidocaine NCT07571889 · Topical Intranasal Anesthetic Block for Reducing the Pain of Botulinum Toxin Inj… | Migraine | Traitement symptomatique | Non applicable | RECRUITING | People find the injections used in onabotulinumtoxinA (Botox®) uncomfortab… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:09 | Détail |
| SOMATIN — Multimodal Therapy for Somatosensory Tinnitus NCT07468318 · NCT07468318 | Migraine | À vérifier | Non applicable | NOT_YET_RECRUITING | Tinnitus (ringing or buzzing in the ears) affects approximately 10-15% of… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:09 | Détail |
| Study on 30 Outpatients With Chronic Migraine Treated With Well-Being… NCT03404336 · NCT03404336 | Migraine | Ralentissement de la progression | Non applicable | RECRUITING | Chronic migraine is a disabling type of migraine and is often resistant to… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:09 | Détail |
| Vibrotactile Stimulation NCT04069572 · Vibratory Stimulation for the Treatment of Chronic Pain | Migraine | Traitement symptomatique | Non applicable | SUSPENDED | The purpose of this study is to perform a first in man study with VCR stim… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:09 | Détail |
| Virtual Reality NCT07374640 · Virtual Reality and Biofeedback for Adolescents With Chronic Dizziness | Migraine | Traitement symptomatique | Phase 1 | NOT_YET_RECRUITING | Both persistent postural-perceptual dizziness (PPPD) and vestibular migrai… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:09 | Détail |
| Efficacy of Smartphone Based Digital Application in Improving Headach… NCT04984720 · NCT04984720 | Migraine | Traitement symptomatique | Non applicable | COMPLETED | Migraine is a common headache disorder and affects 1 in 5 adults during th… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:08 | Détail |
Découverte scientifique
Recherches et trouvailles 0
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune trouvaille ne correspond aux filtres. | |||||||
Bibliographie
Publications 661
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Efficacy of Greater Occipital Nerve Blockade in Craniofacial Neuralgi… Greater Occipital Nerve Block with dexamethasone and lidocaine · PMID 40725724 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source : Greater occipital nerve blockade (GONB) is a minimally invasive intervention used to treat primary headaches. However… | Journal of clinical medicine 2026-08-08 00:59:43 | Source |
| Greater occipital nerve blockade for the preventive treatment of chro… Greater Occipital Nerve Block with 0.9% saline · PMID 36739512 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Greater occipital nerve blockade for the prevention of chronic migraine has a limited evidence base. A robust randomize… | Cephalalgia : an international journal of headache 2026-08-08 00:59:43 | Source |
| Three men in a boat: The comparison of the combination therapy of bot… Greater Occipital Nerve Block with 0.9% saline · PMID 36731164 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source This study compared the impact of the combination therapy of onabotulinum toxin A and greater occipital nerve block (Go… | Clinical neurology and neurosurgery 2026-08-08 00:59:43 | Source |
| High dosage accelerated intermittent theta burst stimulation without… tDCS device from neuroConn · PMID 40705070 | Migraine | À vérifier | Publication | PubMed | Voir la publication source High dosage accelerated intermittent theta-burst stimulation (aiTBS) protocols (10 sessions per day for 5 days) combine… | European archives of psychiatry and clinical neuroscie… 2026-08-08 00:59:42 | Source |
| Report Approval for Transcranial Electrical Stimulation (RATES): expe… tDCS device from neuroConn · PMID 41044265 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Transcranial electrical stimulation (tES) has gained substantial momentum as a research and therapeutic tool; however,… | Nature protocols 2026-08-08 00:59:42 | Source |
| Artificial intelligence-based decision support in simulated free flap… Migraine surgery · PMID 42326044 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Free flap compromise after head and neck reconstruction requires rapid recognition and structured escalation. Large lan… | JPRAS open 2026-08-08 00:59:41 | Source |
| Corrugator Supercilii Muscle and Its Relationship with Neurovascular… Migraine surgery · PMID 42192010 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source The corrugator supercilii muscle (CSM) is a critical anatomical target for botulinum toxin injections and surgical inte… | Aesthetic plastic surgery 2026-08-08 00:59:41 | Source |
| Efficacy and tolerability of combination treatment of topiramate and… PROMPT-IN — A Study of Prophylaxis for Migraine Patients With Topiramate in India · PMID 35259… | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source To compare the efficacy and tolerability of combination treatment of topiramate and greater occipital nerve block to to… | Cephalalgia : an international journal of headache 2026-08-08 00:59:40 | Source |
| Vitamin D Deficiency and Supplementation in Migraine: A Scoping Revie… PROMPT-IN — A Study of Prophylaxis for Migraine Patients With Topiramate in India · PMID 41233… | Migraine | Ralentissement de la progression · Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Migraine is a debilitating neurological disorder affecting 10%-20% of the global population, with significant socioecon… | Annals of Indian Academy of Neurology 2026-08-08 00:59:40 | Source |
| A Phase I, Randomized, Single‑Blind, Placebo‑Controlled, Single Ascen… Part B: TRV250 Dose 1 · PMID 32676977 | Migraine | À vérifier | Publication | PubMed | Voir la publication source The delta opioid receptor (DOR) has been identified as a therapeutic target for migraine, with DOR agonists exhibiting… | CNS drugs 2026-08-08 00:59:37 | Source |
| Investigation of a foodborne outbreak of Shigella sonnei in Ireland a… Part A: TRV250-20mg/ml · PMID 32120067 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source To describe a cross-border foodborne outbreak of Shigella sonnei that occurred in Ireland and Northern Ireland (NI) in… | Public health 2026-08-08 00:59:36 | Source |
| Outbreak of hepatitis A infection associated with the consumption of… Part A: TRV250-20mg/ml · PMID 25375902 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source In May 2013, a European alert was issued regarding a hepatitis A virus (HAV) outbreak in Italy. In June 2013, HAV subge… | Euro surveillance : bulletin Europeen sur les maladies… 2026-08-08 00:59:36 | Source |
| Alterations of Resting-State Locus Coeruleus Functional Connectivity… Cefaly device · PMID 35619611 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Transdermal trigeminal electrical neuromodulation (TTEN) is a novel treatment modality that is known for noradrenergic… | Frontiers in psychiatry 2026-08-08 00:59:33 | Source |
| Efficacy of ultrasound-guided greater occipital nerve pulsed radiofre… Efficacy of Greater Occipital Nerve Radiofrequency for Refractory Migraine Treatment · PMID 35… | Migraine | Ralentissement de la progression · Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Ultrasound (US) guided pulsed radiofrequency (PRF) therapy can be used on the greater occipital nerve (GON) in patients… | Acta neurologica Belgica 2026-08-08 00:59:33 | Source |
| Evidence-Based Patient Selection in Headache Surgery: Impact of Preop… Efficacy of Greater Occipital Nerve Radiofrequency for Refractory Migraine Treatment · PMID 36… | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Radiofrequency ablation (RFA) of the greater occipital nerve (GON) is a minimally invasive treatment option commonly us… | Plastic and reconstructive surgery 2026-08-08 00:59:33 | Source |
| Peripheral Neuromodulation for the Management of Headache. Cefaly device · PMID 34150578 | Migraine | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Neuromodulation is an expanding field of study for headache treatment to reduce pain by targeting structures within the… | Anesthesiology and pain medicine 2026-08-08 00:59:33 | Source |
| Phentermine/Topiramate in Obese, Diabetic Uric Acid Stone Formers: An… Topiramate 100 mg · PMID 42361212 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source The purpose of this study was to determine whether medical treatment of obesity, diabetes, and low urine pH with combin… | The Journal of urology 2026-08-08 00:59:31 | Source |
| Use of obesity medications in a young pediatric patient with optic ne… Topiramate 100 mg · PMID 40698016 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Pediatric obesity presents complex challenges in children with underlying endocrine disorders. In patients with optic n… | Obesity pillars 2026-08-08 00:59:31 | Source |
| Atogepant Reduces Psychological Dependence on Acute Treatments Evalua… Atogepant 60 mg · PMID 42494172 | Migraine | À vérifier | Publication | PubMed | Voir la publication source The Leeds Dependence Questionnaire (LDQ) is a validated tool for assessing psychological dependence across various subs… | Brain and behavior 2026-08-08 00:59:30 | Source |
| Blood pressure lowering for prevention of episodic migraine: results… Propranolol 160 mg · PMID 41036277 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Beta blockers are effective in migraine prevention. Low-dose combination therapy of blood pressure lowering is likely t… | Frontiers in neurology 2026-08-08 00:59:30 | Source |
Exploration — prudence
Pistes exploratoires 5
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Bavisant BRAVEinMS — Bavisant | Migraine | Remyélinisation · Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Antagonisme du récepteur H3 de l’histamine Bavisant est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migra… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| Tol-MP Tol-MP — tolérance immunitaire spécifique de la myéline | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Microparticules biodégradables chargées en rapamycine et fonctionnalisées… Tol-MP est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migrain… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| SetPoint System SetPoint System — SetPoint Medical | Migraine | Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | re ApplicationsPublicationsCompanyCareersNewsGet startedGet startedNewsThe… SetPoint System est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation immunométabolique de la microglie 4-octyl itaconate et dérivés est étudié dans Sclérose latérale amyotrophique et documente plusieurs axes biologiques po… | Rapprochement Biomedical Watch · Sclérose latérale amy… | Détail |
| N-PPG N-PPG — modulation métabolique cérébrale | Migraine | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation métabolique et mitohormèse N-PPG est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être pertinents pour Migrai… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |