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Migraine
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1236 résultats correspondants
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dans le périmètre Migraine
Niveau clinique
Études et traitements 570
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| ReMMi-D Digital Therapeutic NCT05853900 · ReMMi-D — Study of Two Digital Therapeutics for the Prevention of Episodic Migra… | Migraine | À vérifier | Non applicable | COMPLETED | Randomized study of two digital therapeutics for the prevention of episodi… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:12 | Détail |
| SPHERA_WP2 — Searching for Novel Therapeutic Approaches in Migraine P… NCT06562400 · NCT06562400 | Migraine | À vérifier | À vérifier | RECRUITING | Primary working hypothesis is that NON-responders to mAbs bear a dysfuncti… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:12 | Détail |
| 5% lidocaine/5 mg/ml 0.02% estradiol compound cream NCT03844412 · Vestibulodynia: Understanding Pathophysiology and Determining Appropriate Treatm… | Migraine | Traitement symptomatique · Thérapie génique | Phase 2 | COMPLETED | Vestibulodynia (VBD) is a complex chronic vulvar pain condition that impai… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:09 | Détail |
| Bupivacaine NCT07497646 · GONBLOCK-RCT — Repeated Bilateral Greater Occipital Nerve Blockade in Chronic Mi… | Migraine | Ralentissement de la progression · Thérapie génique | Non applicable | COMPLETED | This multicenter, randomized, double-blind, placebo-controlled clinical tr… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:09 | Détail |
| CBD 100 mg OD NCT03972124 · Cannabis for the Prophylactic Treatment of Migraine | Migraine | À vérifier | Phase 2 | RECRUITING | This study will evaluate the efficacy and safety of cannabis for the treat… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:09 | Détail |
| Emgality 120 MG in 1 ML Prefilled Syringe NCT04271202 · Novel Insight Into Migraine Pathophysiolgy and Galcanezumab Mechanisms of Action | Migraine | À vérifier | Phase 4 | COMPLETED | The purpose of this study is to understand better the mechanisms of action… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:09 | Détail |
| Greater occiptal nerve block NCT07512219 · Comparison Between Greater Occipital Nerve Block and Pulsed Radiofrequency in th… | Migraine | À vérifier | Non applicable | NOT_YET_RECRUITING | Comparative Study of Greater Occipital Nerve Block and Pulsed Radiofrequen… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:09 | Détail |
| HEAD-TMD — Pericranial and General Sensitivity in Patients With Prima… NCT07514208 · NCT07514208 | Migraine | Ralentissement de la progression · Traitement symptomatique | À vérifier | ENROLLING_BY_INVITATION | Primary headaches such as migraine and tension type headache are among the… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:09 | Détail |
| Mind Body Intervention for Chronic Migraine Headaches NCT06690060 · NCT06690060 | Migraine | À vérifier | Non applicable | RECRUITING | The goal of this exploratory study is to test a mind-body interventional a… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:09 | Détail |
| Neurostimulator NCT06167655 · A PIVOTAL STUDY EVALUATING SAFETY AND EFFICACY OF THE SHIRATRONICS MIGRAINE THER… | Migraine | À vérifier | Non applicable | ACTIVE_NOT_RECRUITING | The purpose of this pivotal clinical study is to evaluate the safety and e… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:09 | Détail |
| Non-Invasive Brain Stimulation as Add-on Treatment in Chronic Migrain… NCT07442916 · NCT07442916 | Migraine | À vérifier | Non applicable | COMPLETED | This randomized, double-blind, sham-controlled clinical trial aims to eval… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:09 | Détail |
| Nurse Intervention Trial NCT06200480 · NCT06200480 | Migraine | À vérifier | Non applicable | TERMINATED | This randomized open-label prospective study focus on headache patients in… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:09 | Détail |
| occipital nerve stimulator NCT06022848 · Quantitative Sensory Testing and Occipital Nerve Stimulator | Migraine | Traitement symptomatique | Non applicable | COMPLETED | The primary aim of this study is to assess the reversibility of a range of… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:09 | Détail |
| OnabotulinumtoxinA NCT07535723 · Botulinum Toxin and/or Greater Occipital Nerve Block for Patients With Chronic M… | Migraine | À vérifier | Non applicable | NOT_YET_RECRUITING | Chronic migraine is a debilitating neurological disorder that significantl… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:09 | Détail |
| onabotulinumtoxinA prophylaxis with Lidocaine NCT07571889 · Topical Intranasal Anesthetic Block for Reducing the Pain of Botulinum Toxin Inj… | Migraine | Traitement symptomatique | Non applicable | RECRUITING | People find the injections used in onabotulinumtoxinA (Botox®) uncomfortab… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:09 | Détail |
| SOMATIN — Multimodal Therapy for Somatosensory Tinnitus NCT07468318 · NCT07468318 | Migraine | À vérifier | Non applicable | NOT_YET_RECRUITING | Tinnitus (ringing or buzzing in the ears) affects approximately 10-15% of… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:09 | Détail |
| Study on 30 Outpatients With Chronic Migraine Treated With Well-Being… NCT03404336 · NCT03404336 | Migraine | Ralentissement de la progression | Non applicable | RECRUITING | Chronic migraine is a disabling type of migraine and is often resistant to… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:09 | Détail |
| Vibrotactile Stimulation NCT04069572 · Vibratory Stimulation for the Treatment of Chronic Pain | Migraine | Traitement symptomatique | Non applicable | SUSPENDED | The purpose of this study is to perform a first in man study with VCR stim… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:09 | Détail |
| Virtual Reality NCT07374640 · Virtual Reality and Biofeedback for Adolescents With Chronic Dizziness | Migraine | Traitement symptomatique | Phase 1 | NOT_YET_RECRUITING | Both persistent postural-perceptual dizziness (PPPD) and vestibular migrai… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:09 | Détail |
| Efficacy of Smartphone Based Digital Application in Improving Headach… NCT04984720 · NCT04984720 | Migraine | Traitement symptomatique | Non applicable | COMPLETED | Migraine is a common headache disorder and affects 1 in 5 adults during th… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:08 | Détail |
Découverte scientifique
Recherches et trouvailles 0
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune trouvaille ne correspond aux filtres. | |||||||
Bibliographie
Publications 661
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Active machine learning model for the dynamic simulation and growth m… TI-001 · PMID 38184678 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Substrate-catalyzed growth offers a highly promising approach for the controlled synthesis of carbon nanostructures. Ho… | Nature communications 2026-08-08 00:59:56 | Source |
| Combined Occipital Nerve and Sphenopalatine Ganglion Neuromodulation… Occipital Nerve Stimulation · PMID 42100751 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Craniofacial complex regional pain syndrome (CRPS) is a rare, diagnostically challenging condition characterized by sym… | Local and regional anesthesia 2026-08-08 00:59:56 | Source |
| Comparative Efficacy and Acceptability of Noninvasive Brain Stimulati… Occipital Nerve Stimulation · PMID 42473074 | Migraine | À vérifier | Publication | PubMed | Voir la publication source This network meta-analysis (NMA) aimed to compare and rank the efficacy and acceptability of different noninvasive brai… | Brain and behavior 2026-08-08 00:59:56 | Source |
| TiO2 nanotubes: interdependence of substrate grain orientation and gr… TI-001 · PMID 25545715 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Highly ordered arrays of TiO2 nanotubes can be produced by self-organized anodic growth. It is desirable to identify ke… | ACS applied materials & interfaces 2026-08-08 00:59:56 | Source |
| International Headache society evidence-based guidelines on the use o… Nerivio Migra-1 Sham device · PMID 41117312 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source ObjectiveTo develop evidence-based clinical practice guidelines for non-invasive neuromodulation devices in acute and p… | Cephalalgia : an international journal of headache 2026-08-08 00:59:54 | Source |
| Plasma Phosphorylated Tau 217 in Participants at Risk for Chronic Tra… BE WELL With Migraine: Brain Education and WELLness With Migraine · PMID 42440317 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source In vivo biomarkers for detecting neuropathologies from repetitive head impacts (RHI), including chronic traumatic encep… | JAMA network open 2026-08-08 00:59:53 | Source |
| Weight loss with atogepant in the long-term treatment of migraine: An… BE WELL With Migraine: Brain Education and WELLness With Migraine · PMID 42396885 | Migraine | À vérifier | Publication | PubMed | Voir la publication source To assess weight loss with atogepant 60 mg once daily during long-term treatment of chronic migraine (CM) and episodic… | Headache 2026-08-08 00:59:53 | Source |
| Cellulose and Its Derivatives in Drug Delivery: Recent Advances and A… sumatriptan succinate · PMID 42198288 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Drug delivery systems have long faced a fundamental challenge: achieving high drug-loading efficiency, precise control… | Pharmaceutics 2026-08-08 00:59:51 | Source |
| Spatial metabolomics combined with MALDI-MSI unveils gut-brain axis m… sumatriptan succinate · PMID 41619552 | Migraine | Immunomodulation · Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Migraine is a highly disabling neurological disorder characterized by recurrent headaches and complex metabolic disturb… | Phytomedicine : international journal of phytotherapy… 2026-08-08 00:59:51 | Source |
| Drugs targeting nitric oxide synthase for migraine treatment. NXN-188 · PMID 24818644 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Ample evidence that nitric oxide (NO) is a causative molecule in migraine has encouraged research to develop drugs that… | Expert opinion on investigational drugs 2026-08-08 00:59:50 | Source |
| The nitric oxide synthase inhibitor and serotonin-receptor agonist NX… NXN-188 · PMID 29913885 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Background and aims NXN-188 is a combined neuronal nitric oxide synthase (nNOS) inhibitor and 5HT-1B/1D receptor agonis… | Scandinavian journal of pain 2026-08-08 00:59:50 | Source |
| Identifying central positional vertigo to prevent diagnostic pitfalls… Vestibular System in Migrainous Vertigo Patients · PMID 42564662 | Migraine | À vérifier | Publication | PubMed | Voir la publication source This case series highlights the critical role of radiological imaging in patients presenting with positional vertigo in… | Radiology case reports 2026-08-08 00:59:48 | Source |
| Quantitative pupillometry as a marker of autonomic dysregulation in v… Vestibular System in Migrainous Vertigo Patients · PMID 42548108 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source Vestibular migraine (VM) has been associated with altered central sensory processing; however, objective measures of au… | Journal of oral & facial pain and headache 2026-08-08 00:59:48 | Source |
| Arterial hepatic perfusion is preserved during early resuscitation af… blood withdrawal · PMID 42431156 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Hemorrhagic shock is a major contributor to morbidity and mortality after polytrauma and plays a central role in the de… | Injury 2026-08-08 00:59:47 | Source |
| Long peripheral catheters for short-term vascular access: A 7-day obs… blood withdrawal · PMID 42438309 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source Long peripheral catheters are increasingly used as an alternative to short peripheral catheters for short-term intraven… | The journal of vascular access 2026-08-08 00:59:47 | Source |
| A Real-World Evidence Study on US Patients Demonstrating Safety of Hi… Nerivio ® · PMID 41886224 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Remote electrical neuromodulation (REN) is an FDA-cleared, nonsignificant-risk, drug-free, prescribed wearable device (… | Pain and therapy 2026-08-08 00:59:45 | Source |
| Association of adverse childhood experiences with physical illness an… Brief Interventions in Chronic Migraine · PMID 40194777 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Adverse childhood experiences (ACEs) are highly prevalent and associated with life-long health consequences. Here, we i… | European journal of public health 2026-08-08 00:59:45 | Source |
| Non-Pharmacological Treatment of Primary Headaches-A Focused Review. Brief Interventions in Chronic Migraine · PMID 37891800 | Migraine | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Headache disorders are a significant global health burden, leading to reduced quality of life. While vast pharmacologic… | Brain sciences 2026-08-08 00:59:45 | Source |
| U.S. Veterans Using Remote Electrical Neuromodulation for Migraine: A… Nerivio ® · PMID 42520312 | Migraine | Ralentissement de la progression · Traitement symptomatique | Publication | PubMed | Voir la publication source Among U.S. veterans, migraine and other headache disorders are common, and frequently co-occur with other comorbidities… | Military medicine 2026-08-08 00:59:45 | Source |
| 2025 guideline update to acute treatment of migraine for adults in th… Greater Occipital Nerve Block with dexamethasone and lidocaine · PMID 41321235 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source To update the 2016 American Headache Society (AHS) guideline on parenteral pharmacologic therapies for the management o… | Headache 2026-08-08 00:59:43 | Source |
Exploration — prudence
Pistes exploratoires 5
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Bavisant BRAVEinMS — Bavisant | Migraine | Remyélinisation · Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Antagonisme du récepteur H3 de l’histamine Bavisant est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migra… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| Tol-MP Tol-MP — tolérance immunitaire spécifique de la myéline | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Microparticules biodégradables chargées en rapamycine et fonctionnalisées… Tol-MP est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migrain… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| SetPoint System SetPoint System — SetPoint Medical | Migraine | Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | re ApplicationsPublicationsCompanyCareersNewsGet startedGet startedNewsThe… SetPoint System est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation immunométabolique de la microglie 4-octyl itaconate et dérivés est étudié dans Sclérose latérale amyotrophique et documente plusieurs axes biologiques po… | Rapprochement Biomedical Watch · Sclérose latérale amy… | Détail |
| N-PPG N-PPG — modulation métabolique cérébrale | Migraine | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation métabolique et mitohormèse N-PPG est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être pertinents pour Migrai… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |