Vue transversale de la maladie
Migraine
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
Périmètre
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1236 résultats correspondants
· 45 visibles sur cette page
dans le périmètre Migraine
Niveau clinique
Études et traitements 570
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Rimegepant NCT03461757 · Trial in Adult Subjects With Acute Migraines | Migraine | À vérifier | Phase 3 | COMPLETED | The purpose of this study is to evaluate safety and tolerability of BHV-30… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:17 | Détail |
| Wristband with millimeter wave emission. NCT04568252 · MISTIC — Migraine STImulation Crisis of Migraine | Migraine | À vérifier | Non applicable | COMPLETED | Migraine is a neurovascular disease whose prevalence is estimated at almos… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:17 | Détail |
| CoolStat active device NCT04936061 · Transnasal Cooling for Migraine | Migraine | Traitement symptomatique | Non applicable | TERMINATED | This is a prospective, double-blind, sham-controlled, randomized study to… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:15 | Détail |
| Dihydroergotamine NCT04406649 · ASCEND — A Study to Evaluate the Safety of STS101 in the Acute Treatment of Migr… | Migraine | À vérifier | Phase 3 | COMPLETED | Study STS101-007 is a randomized, double-blind, parallel group, placebo-co… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:15 | Détail |
| Dihydroergotamine NCT03901482 · EMERGE — A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate STS101… | Migraine | À vérifier | Phase 3 | COMPLETED | Study STS101-007 is a randomized, double-blind, parallel group, placebo-co… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:15 | Détail |
| Levcromakalim NCT05889442 · COLLIDE — Effect of Levcromakalim in Individuals With Migraine Pretreated With E… | Migraine | À vérifier | Non applicable | COMPLETED | This study aims to explore the effect of Ivabradine on Levcromakalim-induc… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:15 | Détail |
| MLTM — Pilot Study for a Machine Learning Test for Migraine NCT05517200 · NCT05517200 | Migraine | Thérapie génique | À vérifier | UNKNOWN | This study is a single center, random participant selection, data analyst… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:15 | Détail |
| Sildenafil NCT05889455 · COMPETE — Effect of Sildenafil in Individuals With Migraine Pretreated With Eren… | Migraine | À vérifier | Non applicable | COMPLETED | This study is done to evaluate whether treatment with the drug sildenafil… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:15 | Détail |
| sumatriptan nasal powder NCT03338920 · Study to Assess the Safety and Efficacy of ONZETRA® Xsail® for the Acute Treatme… | Migraine | À vérifier | Phase 3 | TERMINATED | This study will be conducted to evaluate the safety and efficacy of sumatr… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:15 | Détail |
| Anisodine Hydrobromide NCT05416476 · ATEM — Anisodine Hydrobromide For The Preventive Treatment Of Episodic Migraine | Migraine | À vérifier | Phase 3 | UNKNOWN | In this study,288 adult migraine patients aged 18-65 years (diagnosed with… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:14 | Détail |
| Dihydroergotamine NCT04940390 · SUMMIT — A Randomized, Double-Blind, Parallel Group, Placebo-Controlled Study to… | Migraine | À vérifier | Phase 3 | COMPLETED | Study STS101-007 is a randomized, double-blind, parallel group, placebo-co… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:14 | Détail |
| Fremanezumab Prefilled Syringe NCT06244823 · The FreMRI Study: Advanced MRI on Migraine Patients Treated With Fremanezumab | Migraine | À vérifier | Phase 4 | UNKNOWN | The goal of this open-label, single-blind, controlled-trial is to evaluate… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:14 | Détail |
| Low-Dose Naltrexone and Acetaminophen Combination NCT03194555 · The Preventive Treatment of Migraine With Low-Dose Naltrexone and Acetaminophen… | Migraine | À vérifier | Phase 2 | COMPLETED | The Preventive Treatment of Migraine with Low-Dose Naltrexone and Acetamin… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:14 | Détail |
| Migraine With Aura and Patent Foramen Ovale: Identification of Biomar… NCT06046508 · NCT06046508 | Migraine | Traitement symptomatique | À vérifier | UNKNOWN | This is a multicenter prospective observational study aimed to asses wheth… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:14 | Détail |
| Mindfulness and Mechanisms of Pain Processing in Adults With Migraines NCT02695498 · NCT02695498 | Migraine | Traitement symptomatique | Non applicable | COMPLETED | Although many adults with migraines use non-pharmacological treatment opti… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:14 | Détail |
| Naltrexone and Acetaminophen NCT06245902 · ANODYNE-1 — An Acute Migraine Factorial Study | Migraine | À vérifier | Phase 2 | COMPLETED | The study consists of a screening visit, out-patient treatment of a modera… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:14 | Détail |
| patent foramen ovale closure NCT03521193 · LEARNER — pLatelEts And MigRaine iN patEnt foRamen Ovale | Migraine | Traitement symptomatique | Non applicable | COMPLETED | Migraine is a common, chronic neurovascular disorder characterized by atta… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:14 | Détail |
| Patients with migraine treated with triptans, Lasmiditan or Gepants NCT06267664 · Real-world Effectiveness and Tolerability of Triptans-Ditans-Gepants (TRIDIGEP) | Migraine | Ralentissement de la progression · Traitement symptomatique · Thérapie génique | À vérifier | UNKNOWN | Migraine is the third most prevalent disease and the leading reason of yea… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:14 | Détail |
| Riociguat (BAY 63-2521) NCT05750446 · Effect of Riocigaut on Migraine Attack Induction in People With Migraine | Migraine | À vérifier | Non applicable | COMPLETED | This double-blind, randomized, placebo-controlled cross-over clinical tria… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:14 | Détail |
| rizatriptan NCT00894556 · A Study to Evaluate the Efficacy and Tolerability of Rizatriptan for Treatment o… | Migraine | À vérifier | Phase 3 | COMPLETED | A study to provide evidence supporting the benefit of Rizatriptan in patie… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:14 | Détail |
Découverte scientifique
Recherches et trouvailles 0
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune trouvaille ne correspond aux filtres. | |||||||
Bibliographie
Publications 661
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| An evaluation of peripheral nerve damage that may develop following i… Bupivacaine HCl 0.5% Injectable Solution · PMID 42251255 | Migraine | Immunomodulation | Publication | PubMed | Voir la publication source This study aimed to investigate the histopathological, electrophysiological, functional, biochemical, and inflammatory… | BMC anesthesiology 2026-08-16 19:24:47 | Source |
| Does Liposomal Bupivacaine Provide Superior Postoperative Analgesia C… Bupivacaine HCl 0.5% Injectable Solution · PMID 42284069 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Choosing the most effective pain management is important for enhancing functional recovery after surgery. The fascia il… | Clinical orthopaedics and related research 2026-08-16 19:24:47 | Source |
| Long-term durability of a time-limited methotrexate intervention in p… Methylprednisolone 40 MG Injection · PMID 42392130 | Migraine | Ralentissement de la progression · Immunomodulation | Publication | PubMed | Voir la publication source The TREAT EARLIER trial showed that a time-limited intervention with 12 months of methotrexate in individuals with arth… | The Lancet. Rheumatology 2026-08-16 19:24:47 | Source |
| The true benefit of the regional block in orthognathic surgery lies i… Bupivacaine HCl 0.5% Injectable Solution · PMID 41790271 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source PURPOSE: The objective of this study was to ascertain the actual benefits of regional analgesia in orthognathic surgery… | Oral and maxillofacial surgery 2026-08-16 19:24:47 | Source |
| Use and safety of corticosteroid injections in joints and musculoskel… Methylprednisolone 40 MG Injection · PMID 40015722 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Intra-articular corticosteroid (IACS) injection and peri-articular corticosteroid injection are commonly used to treat… | Regional anesthesia and pain medicine 2026-08-16 19:24:47 | Source |
| Biofeedback in the prophylactic treatment of medication overuse heada… Neurofeedback for Episodic Migraine · PMID 27655371 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Medication overuse headache (MOH) is a major clinical concern and a common health risk. Recent literature stressed the… | The journal of headache and pain 2026-08-16 19:24:46 | Source |
| Neurofeedback and biofeedback with 37 migraineurs: a clinical outcome… Neurofeedback for Episodic Migraine · PMID 20205867 | Migraine | Ralentissement de la progression · Traitement symptomatique | Publication | PubMed | Voir la publication source Traditional peripheral biofeedback has grade A evidence for effectively treating migraines. Two newer forms of neurobio… | Behavioral and brain functions : BBF 2026-08-16 19:24:46 | Source |
| L5-S1 basivertebral nerve ablation for chronic vertebrogenic low back… Chiropractic Care · PMID 42582823 | Migraine | Ralentissement de la progression · Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Basivertebral nerve ablation (BVNA) is an established treatment for vertebrogenic low back pain associated with Modic e… | Journal of spine surgery (Hong Kong) 2026-08-16 19:24:45 | Source |
| Latent Patterns of Complementary and Integrative Health Therapy Utili… Chiropractic Care · PMID 42503189 | Migraine | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Complementary and integrative health (CIH) therapies offer safe and effective alternatives for pain management, and use… | Pain medicine (Malden, Mass.) 2026-08-16 19:24:45 | Source |
| Resolution of Treatment-Resistant Vertigo and Suspected Ménière's Dis… Chiropractic Care · PMID 42534238 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Ménière's disease and related peripheral vestibular disorders are notoriously difficult to manage, and many patients re… | Cureus 2026-08-16 19:24:45 | Source |
| E-selectin and TFPI are associated with carotid intima-media thicknes… Atorvastatin 20mg · PMID 17889518 | Migraine | Immunomodulation | Publication | PubMed | Voir la publication source MIAMI was a prospective multicenter clinical study designed to investigate the relationship between changes in carotid… | Nutrition, metabolism, and cardiovascular diseases : N… 2026-08-16 19:24:43 | Source |
| Evaluation of Flavonoid-rich Fraction of Aerial Part Extract in Ather… Atorvastatin 20mg · PMID 37807415 | Migraine | Neuroprotection · Ralentissement de la progression · Immunomodulation | Publication | PubMed | Voir la publication source is a tiny, upright herb that contains a variety of chemical components, including alkaloids, glycosides, mucilage, prot… | Combinatorial chemistry & high throughput screening 2026-08-16 19:24:43 | Source |
| Expert consensus on drug treatment of chronic subdural hematoma. Atorvastatin 20mg · PMID 34809712 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Chronic subdural hematoma (CSDH) is a chronic space-occupying lesion formed by blood accumulation between arachnoid and… | Chinese neurosurgical journal 2026-08-16 19:24:43 | Source |
| Effects of erenumab on migraine aura frequency: a REFORM study. Erenumab Dose 1 · PMID 41888647 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Anti-calcitonin gene-related peptide (CGRP) monoclonal antibodies effectively prevent migraine headache, but their impa… | The journal of headache and pain 2026-08-16 19:24:39 | Source |
| Efficacy and Safety of Erenumab in Adults With Medication Overuse Hea… Erenumab Dose 1 · PMID 40838472 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Erenumab-induced medication overuse headache (MOH) remission in participants with chronic migraine (CM) in a prospectiv… | European journal of neurology 2026-08-16 19:24:39 | Source |
| Erenumab for Chronic Cluster Headache: A Randomized Clinical Trial. Erenumab Dose 1 · PMID 40526384 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Calcitonin gene-related peptide (CGRP) is involved in the pathophysiology of cluster headache (CH). Prophylactic pharma… | JAMA network open 2026-08-16 19:24:39 | Source |
| Neuro-Immune Axis in Trauma-Induced Heterotopic Ossification: Mechani… Erenumab Dose 2 · PMID 42121928 | Migraine | Immunomodulation · Thérapie génique | Publication | PubMed | Voir la publication source Trauma-induced heterotopic ossification (tHO) is characterized by aberrant ectopic bone formation in soft tissue follow… | Cells 2026-08-16 19:24:39 | Source |
| Advances in ERAS to Reduce the Incidence of Chronic Post-Surgical Pai… Lidocaine Procedure · PMID 42138101 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Chronic postsurgical pain (CPSP) remains a clinically significant complication following major surgery, contributing to… | Journal of investigative surgery : the official journa… 2026-08-16 19:24:38 | Source |
| Comparison of a TrachoSpray Device and Manual Lidocaine Spray on Hemo… Lidocaine Procedure · PMID 41797600 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Postoperative sore throat (POST) is an distressing complication following endotracheal intubation, particularly with do… | Journal of investigative surgery : the official journa… 2026-08-16 19:24:38 | Source |
| Lidocaine Spray Versus Viscous Lidocaine Solution Plus Lidocaine Spra… Lidocaine Procedure · PMID 42559051 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Non-sedated esophagogastroduodenoscopy (EGD) is preferred in patients at risk from sedatives. However, achieving effect… | DEN open 2026-08-16 19:24:38 | Source |
Exploration — prudence
Pistes exploratoires 5
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Bavisant BRAVEinMS — Bavisant | Migraine | Remyélinisation · Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Antagonisme du récepteur H3 de l’histamine Bavisant est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migra… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| Tol-MP Tol-MP — tolérance immunitaire spécifique de la myéline | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Microparticules biodégradables chargées en rapamycine et fonctionnalisées… Tol-MP est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migrain… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| SetPoint System SetPoint System — SetPoint Medical | Migraine | Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | re ApplicationsPublicationsCompanyCareersNewsGet startedGet startedNewsThe… SetPoint System est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation immunométabolique de la microglie 4-octyl itaconate et dérivés est étudié dans Sclérose latérale amyotrophique et documente plusieurs axes biologiques po… | Rapprochement Biomedical Watch · Sclérose latérale amy… | Détail |
| N-PPG N-PPG — modulation métabolique cérébrale | Migraine | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation métabolique et mitohormèse N-PPG est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être pertinents pour Migrai… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |