Vue transversale de la maladie
Migraine
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
Périmètre
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1236 résultats correspondants
· 45 visibles sur cette page
dans le périmètre Migraine
Niveau clinique
Études et traitements 570
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Rimegepant NCT03461757 · Trial in Adult Subjects With Acute Migraines | Migraine | À vérifier | Phase 3 | COMPLETED | The purpose of this study is to evaluate safety and tolerability of BHV-30… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:17 | Détail |
| Wristband with millimeter wave emission. NCT04568252 · MISTIC — Migraine STImulation Crisis of Migraine | Migraine | À vérifier | Non applicable | COMPLETED | Migraine is a neurovascular disease whose prevalence is estimated at almos… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:17 | Détail |
| CoolStat active device NCT04936061 · Transnasal Cooling for Migraine | Migraine | Traitement symptomatique | Non applicable | TERMINATED | This is a prospective, double-blind, sham-controlled, randomized study to… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:15 | Détail |
| Dihydroergotamine NCT04406649 · ASCEND — A Study to Evaluate the Safety of STS101 in the Acute Treatment of Migr… | Migraine | À vérifier | Phase 3 | COMPLETED | Study STS101-007 is a randomized, double-blind, parallel group, placebo-co… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:15 | Détail |
| Dihydroergotamine NCT03901482 · EMERGE — A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate STS101… | Migraine | À vérifier | Phase 3 | COMPLETED | Study STS101-007 is a randomized, double-blind, parallel group, placebo-co… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:15 | Détail |
| Levcromakalim NCT05889442 · COLLIDE — Effect of Levcromakalim in Individuals With Migraine Pretreated With E… | Migraine | À vérifier | Non applicable | COMPLETED | This study aims to explore the effect of Ivabradine on Levcromakalim-induc… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:15 | Détail |
| MLTM — Pilot Study for a Machine Learning Test for Migraine NCT05517200 · NCT05517200 | Migraine | Thérapie génique | À vérifier | UNKNOWN | This study is a single center, random participant selection, data analyst… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:15 | Détail |
| Sildenafil NCT05889455 · COMPETE — Effect of Sildenafil in Individuals With Migraine Pretreated With Eren… | Migraine | À vérifier | Non applicable | COMPLETED | This study is done to evaluate whether treatment with the drug sildenafil… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:15 | Détail |
| sumatriptan nasal powder NCT03338920 · Study to Assess the Safety and Efficacy of ONZETRA® Xsail® for the Acute Treatme… | Migraine | À vérifier | Phase 3 | TERMINATED | This study will be conducted to evaluate the safety and efficacy of sumatr… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:15 | Détail |
| Anisodine Hydrobromide NCT05416476 · ATEM — Anisodine Hydrobromide For The Preventive Treatment Of Episodic Migraine | Migraine | À vérifier | Phase 3 | UNKNOWN | In this study,288 adult migraine patients aged 18-65 years (diagnosed with… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:14 | Détail |
| Dihydroergotamine NCT04940390 · SUMMIT — A Randomized, Double-Blind, Parallel Group, Placebo-Controlled Study to… | Migraine | À vérifier | Phase 3 | COMPLETED | Study STS101-007 is a randomized, double-blind, parallel group, placebo-co… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:14 | Détail |
| Fremanezumab Prefilled Syringe NCT06244823 · The FreMRI Study: Advanced MRI on Migraine Patients Treated With Fremanezumab | Migraine | À vérifier | Phase 4 | UNKNOWN | The goal of this open-label, single-blind, controlled-trial is to evaluate… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:14 | Détail |
| Low-Dose Naltrexone and Acetaminophen Combination NCT03194555 · The Preventive Treatment of Migraine With Low-Dose Naltrexone and Acetaminophen… | Migraine | À vérifier | Phase 2 | COMPLETED | The Preventive Treatment of Migraine with Low-Dose Naltrexone and Acetamin… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:14 | Détail |
| Migraine With Aura and Patent Foramen Ovale: Identification of Biomar… NCT06046508 · NCT06046508 | Migraine | Traitement symptomatique | À vérifier | UNKNOWN | This is a multicenter prospective observational study aimed to asses wheth… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:14 | Détail |
| Mindfulness and Mechanisms of Pain Processing in Adults With Migraines NCT02695498 · NCT02695498 | Migraine | Traitement symptomatique | Non applicable | COMPLETED | Although many adults with migraines use non-pharmacological treatment opti… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:14 | Détail |
| Naltrexone and Acetaminophen NCT06245902 · ANODYNE-1 — An Acute Migraine Factorial Study | Migraine | À vérifier | Phase 2 | COMPLETED | The study consists of a screening visit, out-patient treatment of a modera… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:14 | Détail |
| patent foramen ovale closure NCT03521193 · LEARNER — pLatelEts And MigRaine iN patEnt foRamen Ovale | Migraine | Traitement symptomatique | Non applicable | COMPLETED | Migraine is a common, chronic neurovascular disorder characterized by atta… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:14 | Détail |
| Patients with migraine treated with triptans, Lasmiditan or Gepants NCT06267664 · Real-world Effectiveness and Tolerability of Triptans-Ditans-Gepants (TRIDIGEP) | Migraine | Ralentissement de la progression · Traitement symptomatique · Thérapie génique | À vérifier | UNKNOWN | Migraine is the third most prevalent disease and the leading reason of yea… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:14 | Détail |
| Riociguat (BAY 63-2521) NCT05750446 · Effect of Riocigaut on Migraine Attack Induction in People With Migraine | Migraine | À vérifier | Non applicable | COMPLETED | This double-blind, randomized, placebo-controlled cross-over clinical tria… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:14 | Détail |
| rizatriptan NCT00894556 · A Study to Evaluate the Efficacy and Tolerability of Rizatriptan for Treatment o… | Migraine | À vérifier | Phase 3 | COMPLETED | A study to provide evidence supporting the benefit of Rizatriptan in patie… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:14 | Détail |
Découverte scientifique
Recherches et trouvailles 0
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune trouvaille ne correspond aux filtres. | |||||||
Bibliographie
Publications 661
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Rizatriptan as an Over-the-Counter Triptan in the Treatment of Migrai… Sumatriptan 50 mg · PMID 38886287 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Around 91% of migraine patients use over-the-counter medicines to treat attacks, often without further treatment or med… | Pain and therapy 2026-08-16 21:22:02 | Source |
| Comparing the efficacy of eletriptan for migraine in women during men… Eletriptan 20 mg · PMID 24256184 | Migraine | Ralentissement de la progression | Publication | PubMed | Voir la publication source To assess the efficacy and tolerability of eletriptan in treating migraine attacks occurring within the defined menstru… | Headache 2026-08-16 21:22:01 | Source |
| Economic analysis of triptan therapy for acute migraine: a Medicaid p… Eletriptan 20 mg · PMID 17655509 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source To compare triptan therapies for migraine in terms of the cost to treat 100 migraine attacks and the cost per successfu… | Pharmacotherapy 2026-08-16 21:22:01 | Source |
| Perimenstrual eletriptan prevents menstrual migraine: an open-label s… Eletriptan 20 mg · PMID 20236337 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source To prospectively evaluate the efficacy of perimenstrual prophylaxis with eletriptan to reduce headaches in women identi… | Headache 2026-08-16 21:22:01 | Source |
| Massively parallel single-cell chromatin landscapes of human immune c… CBD 200 mg OD · PMID 31375813 | Migraine | Immunomodulation | Publication | PubMed | Voir la publication source Understanding complex tissues requires single-cell deconstruction of gene regulation with precision and scale. Here, we… | Nature biotechnology 2026-08-16 19:26:32 | Source |
| Motor function of the opossum sphincter of Oddi. CBD 200 mg OD · PMID 6822661 | Migraine | À vérifier | Publication | PubMed | Voir la publication source We studied the opossum sphincter of Oddi (SO) because in this species the SO is approximately 3 cm in length and its ex… | The Journal of clinical investigation 2026-08-16 19:26:32 | Source |
| Cannabidiol Attenuates Heroin Seeking in Male Rats Associated With No… CBD 100 mg OD · PMID 40992584 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source Opioid use disorder is a chronic relapsing condition characterized by cycles of compulsive drug use, abstinence, and re… | Biological psychiatry 2026-08-16 19:26:31 | Source |
| Maternal ingestion of cannabidiol (CBD) in mice leads to sex-dependen… CBD 100 mg OD · PMID 39481653 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source The consequences of perinatal cannabidiol (CBD) exposure are severely understudied, but are important, given its widesp… | Pharmacology, biochemistry, and behavior 2026-08-16 19:26:31 | Source |
| 1-Deoxynojirimycin attenuates diabetic cardiomyopathy via PI3K/AKT-me… Study on 30 Outpatients With Chronic Migraine Treated With Well-Being Therapy or With a Contro… | Migraine | Remyélinisation indirecte / réparation · Neuroprotection | Publication | PubMed | Voir la publication source 1-Deoxynojirimycin (DNJ), a naturally occurring alkaloid derived from mulberry leaves (Morus alba L.), is a powerful α-… | Journal of ethnopharmacology 2026-08-16 19:26:30 | Source |
| Zhenwu Decoction ameliorates experimental benign prostatic hyperplasi… Study on 30 Outpatients With Chronic Migraine Treated With Well-Being Therapy or With a Contro… | Migraine | Remyélinisation indirecte / réparation · Neuroprotection · Traitement symptomat… | Publication | PubMed | Voir la publication source Zhenwu Decoction (ZWD), first recorded in the Shang Han Lun, is a classical formula used to warm Yang and promote water… | Journal of ethnopharmacology 2026-08-16 19:26:30 | Source |
| A Randomized Controlled Trial of Instillation Protocols Prior to Intr… onabotulinumtoxinA prophylaxis with Lidocaine · PMID 40025238 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Achieving adequate pain relief is crucial for intradetrusor onabotulinumtoxinA treatments for idiopathic overactive bla… | International urogynecology journal 2026-08-16 19:26:28 | Source |
| A phase 1, multicenter, open-label study to evaluate the pharmacokine… Rimegepant 75 mg ODT · PMID 41133671 | Migraine | À vérifier | Publication | PubMed | Voir la publication source To evaluate pharmacokinetics (PK), safety, and tolerability of a weight-adjusted dose of rimegepant orally disintegrati… | Headache 2026-08-16 19:26:27 | Source |
| A randomized open-label study to evaluate the effectiveness and safet… Rimegepant 75 mg ODT · PMID 40734466 | Migraine | À vérifier | Publication | PubMed | Voir la publication source AimTo evaluate rimegepant, a calcitonin gene-related peptide receptor antagonist, for short-term prevention of fasting-… | Cephalalgia : an international journal of headache 2026-08-16 19:26:27 | Source |
| Rimegepant for acute treatment of migraine in triptan-unsuitable adul… Rimegepant 75 mg ODT · PMID 41255093 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source BackgroundA subset of individuals with migraine are unsuitable for triptans due to intolerance, lack of efficacy, or co… | Cephalalgia : an international journal of headache 2026-08-16 19:26:27 | Source |
| Decoding the serotonin-alcohol crosstalk: the role of central seroton… Serotonergic Psychedelic · PMID 42329577 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Serotonin (5-hydroxytryptamine; 5-HT) is a key neuromodulator involved in the regulation of mood, appetite, aggression,… | Pharmacological reports : PR 2026-08-16 19:26:26 | Source |
| Proliferative Effects of the Psychedelic N,N-Dimethyltryptamine (DMT)… Serotonergic Psychedelic · PMID 42427129 | Migraine | Thérapie cellulaire | Publication | PubMed | Voir la publication source The serotonergic psychedelic N,N-dimethyltryptamine (DMT) produces rapid antidepressant effects in preclinical and earl… | ACS chemical neuroscience 2026-08-16 19:26:26 | Source |
| Botulinum toxin effects on biochemical biomarkers related to inflamma… Tear Biomarkers for Migraine · PMID 40035830 | Migraine | Neuroprotection · Immunomodulation · Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Botulinum toxin type A (BoNT) has emerged as a potential alternative to conventional therapies to many debilitating chr… | Journal of neural transmission (Vienna, Austria : 1996) 2026-08-16 19:26:25 | Source |
| Feasibility and Tolerability of Psilocybin for Phantom Limb Pain. Serotonergic Psychedelic · PMID 42567236 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Phantom limb pain (PLP) is a refractory condition defined by pain experienced in a missing limb. Psilocybin, a classica… | The journal of pain 2026-08-16 19:26:25 | Source |
| The ocular surface tear film as a biomarker for systemic health. Tear Biomarkers for Migraine · PMID 40345388 | Migraine | À vérifier | Publication | PubMed | Voir la publication source The tear film is a complex structure with rich interactions with the human body. A growing body of evidence suggests th… | The ocular surface 2026-08-16 19:26:25 | Source |
| [Clinical practice guideline for migraine with traditional Chinese me… Yangxue Qingnao Granules (Pills) · PMID 33350221 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source The present clinical practice guideline was written by experts organized by the special group of key projects in the 13… | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi =… 2026-08-16 19:26:24 | Source |
Exploration — prudence
Pistes exploratoires 5
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Bavisant BRAVEinMS — Bavisant | Migraine | Remyélinisation · Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Antagonisme du récepteur H3 de l’histamine Bavisant est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migra… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| Tol-MP Tol-MP — tolérance immunitaire spécifique de la myéline | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Microparticules biodégradables chargées en rapamycine et fonctionnalisées… Tol-MP est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migrain… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| SetPoint System SetPoint System — SetPoint Medical | Migraine | Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | re ApplicationsPublicationsCompanyCareersNewsGet startedGet startedNewsThe… SetPoint System est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation immunométabolique de la microglie 4-octyl itaconate et dérivés est étudié dans Sclérose latérale amyotrophique et documente plusieurs axes biologiques po… | Rapprochement Biomedical Watch · Sclérose latérale amy… | Détail |
| N-PPG N-PPG — modulation métabolique cérébrale | Migraine | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation métabolique et mitohormèse N-PPG est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être pertinents pour Migrai… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |