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Périmètre

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Chaque choix s’applique immédiatement aux quatre sections. Le filtre « type de SEP » n’apparaît que lorsque la sclérose en plaques est sélectionnée.

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Essais et traitements4050Données cliniques et programmes
Recherches et trouvailles21Pipeline scientifique
Publications4595Références reliées aux maladies
Pistes exploratoires0Hypothèses non validées
8666 résultats correspondants · 41 visibles sur cette page dans le périmètre Toutes les maladies
Niveau clinique

Études et traitements 4050

Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.

Molécule / élément Maladie / population Objectif Phase / stade Statut / preuve Mécanisme / résumé Source Détail
IRE plus checkpoint inhibitor NCT06047015 · Irreversible Electroporation (NanoKnife ®) and Immunotherapy for the Treatment o… Cancer Thérapie génique Phase 1/2 NOT_YET_RECRUITING The goal of this pilot clinical trial is to learn about the combination of… À vérifier ClinicalTrials.gov 2026-08-16 12:59:20 Détail
Irreversible electroporation (NanoKnife® ) NCT04276857 · SMART — Systemic Therapy With a Loco-regional Treatment in Patients With Locally… Cancer Ralentissement de la progression Non applicable RECRUITING Background Pancreatic cancer is one the leading causes of cancer-related d… À vérifier ClinicalTrials.gov 2026-08-16 12:59:20 Détail
Nano Knife NCT02298608 · Efficacy and Safety of IRE for RMs Cancer À vérifier Phase 1/2 UNKNOWN Background: Electroporation or electropermeabilisation is a novel techniqu… À vérifier ClinicalTrials.gov 2026-08-16 12:59:20 Détail
PoEMS — Post-operative Electrical Muscle Stimulation to Stimulate Mus… NCT05997095 · NCT05997095 Cancer À vérifier Non applicable ACTIVE_NOT_RECRUITING Skeletal muscle accounts for approximately 45-55% of total body mass in he… À vérifier ClinicalTrials.gov 2026-08-16 12:59:20 Détail
Sonatherm 600i ablation system NCT02248389 · HIFU-KIDNEY — Evaluation of a Laparoscopic High Intensity Focused Ultrasound Pro… Cancer À vérifier Phase 1 COMPLETED The Sonatherm device provides both advanced imaging (ultrasound guidance)… À vérifier ClinicalTrials.gov 2026-08-16 12:59:20 Détail
Speedboat™ Ultraslim NCT06476678 · Novel Bipolar Radiofrequency Ablation Knife in Esophageal Lesions Cancer À vérifier À vérifier RECRUITING Both Baylor St Luke's Medical Center and Mayo Scottsdale are considered en… À vérifier ClinicalTrials.gov 2026-08-16 12:59:20 Détail
Visualase Thermal Therapy System NCT01377753 · MR Image Guided Therapy in Prostate Cancer Cancer Traitement symptomatique Phase 2 COMPLETED Background: \- One way to treat prostate cancer is to use a laser to direc… À vérifier ClinicalTrials.gov 2026-08-16 12:59:20 Détail
CCHW-delivered CFH-based Cancer Prevention Program Among Chinese Amer… NCT07766252 · NCT07766252 Cancer À vérifier Non applicable COMPLETED This study evaluated a culturally and linguistically tailored cancer preve… À vérifier ClinicalTrials.gov 2026-08-16 12:59:19 Détail
HIFU (Focal One®) NCT03613298 · Treatment by HIFU With Focal One® of Posterior Deep Infiltrating Endometriosis L… Cancer Traitement symptomatique Non applicable COMPLETED Deep invasive endometriosis (DIE) includes lesions of the rectosigmoid. Th… À vérifier ClinicalTrials.gov 2026-08-16 12:59:19 Détail
Irreversible Electroporation (IRE) NCT05512663 · Safety and Efficacy Evaluation of Transperineal Irreversible Electroporation (IR… Cancer À vérifier Non applicable UNKNOWN Most prostate cancer treatment research in the last decade has been focuse… À vérifier ClinicalTrials.gov 2026-08-16 12:59:19 Détail
Standard-of-care surgery NCT06743555 · SAVED LUNG — Surgery After Verifying Existing Disease in Locally Advanced Operab… Cancer À vérifier Phase 1 NOT_YET_RECRUITING The SAVED LUNG study is a pilot Phase I trial evaluating safety and feasib… À vérifier ClinicalTrials.gov 2026-08-16 12:59:19 Détail
TSLPR-CART NCT07572136 · Anti-CRLF2-R/TSLPR Chimeric Antigen Receptor T Cells (TSLPR-CART) in Participant… Cancer Immunomodulation · Thérapie cellulaire · Thérapie génique Phase 1 NOT_YET_RECRUITING Background: B-cell acute lymphoblastic leukemia (B-ALL) is a type of blood… À vérifier ClinicalTrials.gov 2026-08-16 12:59:19 Détail
An Evaluation of the Implementation of the Care and Monitoring at Hom… NCT05904899 · NCT05904899 Cancer À vérifier À vérifier SUSPENDED To understand the experience of patients receiving care in the Care and Mo… À vérifier ClinicalTrials.gov 2026-08-16 12:59:18 Détail
Atezolizumab NCT07388524 · Testing the Impact of an Anti-Cancer Drug, Atezolizumab, After Surgery to Preven… Cancer À vérifier Phase 3 RECRUITING This phase III trial compares the effect of atezolizumab (or atezolizumab… À vérifier ClinicalTrials.gov 2026-08-16 12:59:18 Détail
Belinostat NCT06406465 · A UGT1A1 Genotype-Directed Study of Belinostat Pharmacokinetics and Toxicity Cancer À vérifier Phase 2 RECRUITING Background: High-grade neuroendocrine carcinomas (HGNEC) are cancers that… À vérifier ClinicalTrials.gov 2026-08-16 12:59:18 Détail
Biopsy Procedure NCT06050252 · Testing the Combination of the Anticancer Drug Durvalumab With Chemotherapy (Gem… Cancer À vérifier Phase 2 RECRUITING This phase I/II trial studies the side effects and best dose of pidnarulex… À vérifier ClinicalTrials.gov 2026-08-16 12:59:18 Détail
Biopsy Procedure NCT07281417 · Testing the Addition of Cemiplimab (REGN2810) to Chemotherapy Treatment Given Pr… Cancer À vérifier Phase 2 RECRUITING This phase I/II trial studies the side effects and best dose of pidnarulex… À vérifier ClinicalTrials.gov 2026-08-16 12:59:18 Détail
Bone Scan NCT05691478 · A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patient… Cancer À vérifier Phase 2/3 SUSPENDED This phase III trial compares standard of care hormone therapy plus riboci… À vérifier ClinicalTrials.gov 2026-08-16 12:59:18 Détail
Development of Brief Positive Affect Treatment (PAT) for Caregivers o… NCT05904782 · NCT05904782 Cancer Thérapie génique À vérifier RECRUITING To learn more about the experience and wellbeing of people who provide car… À vérifier ClinicalTrials.gov 2026-08-16 12:59:18 Détail
Effectiveness of Posluma PET Scan for Post-Treatment Monitoring of Pr… NCT07733908 · NCT07733908 Cancer À vérifier Phase 2 NOT_YET_RECRUITING To determine the effectiveness of Posluma PET Scan for monitoring prostate… À vérifier ClinicalTrials.gov 2026-08-16 12:59:18 Détail
Découverte scientifique

Recherches et trouvailles 21

Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.

Molécule / élément Maladie / population Objectif Phase / stade Statut / preuve Mécanisme / résumé Source Détail
4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation Sclérose latérale amyotrophique Neuroprotection · Immunomodulation Découverte fondamentale Exploratoire Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… Revue scientifique 2024-07-01 Détail
Bibliographie

Publications 4595

Références bibliographiques de la base locale et accès à leur source originale.

Molécule / élément Maladie / population Objectif Phase / stade Statut / preuve Mécanisme / résumé Source Détail
Effects of testosterone-augmented multimodal exercise intervention in… Whole-body Electrical Muscle Stimulation Exercise · PMID 41988780 Myasthénie À vérifier Publication PubMed Voir la publication source Spinal cord injury (SCI) leads to profound muscle atrophy, aerobic deconditioning, and metabolic dysfunction. Exercise-… The Journal of clinical endocrinology and metabolism 2026-09-20 04:37:05 Source
Feasibility and acceptability of whole-body electromyostimulation in… Whole-body Electrical Muscle Stimulation Exercise · PMID 42464389 Myasthénie À vérifier Publication PubMed Voir la publication source Evidence on the effectiveness of electromyostimulation (EMS) has been reported in pulmonary rehabilitation, but the ben… Pilot and feasibility studies 2026-09-20 04:37:05 Source
Vestibular contributions adapt to the balance strategies adopted duri… Whole-body Electrical Muscle Stimulation Exercise · PMID 42616645 Myasthénie À vérifier Publication PubMed Voir la publication source Vestibular contributions during walking are not uniform, but vary with gait phase, muscle group, and balance demands. M… Journal of neurophysiology 2026-09-20 04:37:05 Source
Clinical efficacy of abdominal moxibustion at the Zhongji (CV3) in co… Yangyin Roujin Decoction · PMID 42015783 Myopathies Neuroprotection · Traitement symptomatique Publication PubMed Voir la publication source To investigate the clinical effect of abdominal moxibustion at the Zhongji (CV3) combined with Yiqi Tonglin Yangyin dec… Journal of traditional Chinese medicine = Chung i tsa… 2026-09-20 04:37:03 Source
Yiqi Huoxue Yangyin Decoction Ameliorates Diabetic Nephropathy by Tar… Yangyin Roujin Decoction · PMID 42713045 Myopathies À vérifier Publication PubMed Voir la publication source This study aimed to investigate the protective effects and underlying mechanisms of Yiqi Huoxue Yangyin Decoction (YHY)… Diabetes, metabolic syndrome and obesity : targets and… 2026-09-20 04:37:03 Source
Yiqi Huoxue Yangyin Decoction attenuates diabetic nephropathy in mice… Yangyin Roujin Decoction · PMID 42016924 Myopathies Thérapie génique Publication PubMed Voir la publication source Diabetic nephropathy (DN) is a major complication of diabetes with limited therapeutic options. Yiqi Huoxue Yangyin Dec… Frontiers in pharmacology 2026-09-20 04:37:03 Source
Barcoded oligonucleotide system (BOLT) for targeted organ delivery. Immunotherapy · PMID 42733790 Cancer À vérifier Publication PubMed Voir la publication source The therapeutic potential of oligonucleotides (oligos) is limited by insufficient delivery to extrahepatic tissues. In… Bioactive materials 2026-09-20 04:36:56 Source
Dual metabolic checkpoint blockade a 3D-Printed metalloplatform remod… Immunotherapy · PMID 42724565 Cancer Immunomodulation Publication PubMed Voir la publication source The immunosuppressive tumor microenvironment limits the efficacy of therapies that target metabolism. Here we show a st… Bioactive materials 2026-09-20 04:36:56 Source
Oligosaccharide adjuvant-deferred antigen endocytosis promotes cross-… Immunotherapy · PMID 42751513 Cancer Immunomodulation · Thérapie génique Publication PubMed Voir la publication source Antigen cross-presentation by dendritic cells (DCs) is essential for inducing cytotoxic immune responses, which are cru… Bioactive materials 2026-09-20 04:36:56 Source
Feasibility and safety of early discharge after robot-assisted uro-on… Digital care pathway for hypertension · PMID 42671715 Hypertension artérielle À vérifier Publication PubMed Voir la publication source Early discharge after robot-assisted uro-oncologic surgery remains limited by concerns regarding patient safety and the… Journal of robotic surgery 2026-09-20 04:36:49 Source
HomeSafe: Postpartum Hypertensive Care Enabled by Electronic Health R… Digital care pathway for hypertension · PMID 41707683 Hypertension artérielle À vérifier Publication PubMed Voir la publication source The objective is to present stepwise refinements to , an Epic-tethered, population-health-coordinated postpartum pathwa… American journal of perinatology 2026-09-20 04:36:49 Source
Nutraceutical and functional food: efficacy against metabolic disorde… Digital care pathway for hypertension · PMID 42603698 Hypertension artérielle Neuroprotection · Immunomodulation Publication PubMed Voir la publication source The growing global emphasis on health consciousness has significantly increased demand for traditional and complementar… Journal of advanced research 2026-09-20 04:36:49 Source
Community-engaged design of a virtual diabetes prevention program int… Asynchronous communication with nurse · PMID 42288862 Hypertension artérielle À vérifier Publication PubMed Voir la publication source The Diabetes Prevention Program (DPP) is an evidence-based approach to prevent Type 2 Diabetes (T2D), the leading cause… BMC health services research 2026-09-20 04:36:48 Source
Evolving Lung Cancer Navigator Practice Through Targeted Professional… Asynchronous communication with nurse · PMID 42463006 Cancer À vérifier Publication PubMed Voir la publication source Lung cancer remains the leading cause of cancer deaths worldwide, and it has persistent disparities in detection, treat… Chest 2026-09-20 04:36:48 Source
Mass casualty training for prehospital and emergency providers in Kig… Asynchronous communication with nurse · PMID 42751142 Hypertension artérielle À vérifier Publication PubMed Voir la publication source A mass casualty incident (MCI) occurs when the number of patients exceeds available healthcare resources, placing signi… African journal of emergency medicine : Revue africain… 2026-09-20 04:36:48 Source
Innovating a Teach-Back Model for Community Health Workers Led Health… Health Literacy Project · PMID 40194526 Épilepsie À vérifier Publication PubMed Voir la publication source From 2021 to 2023, the City of Albuquerque, the University of New Mexico (UNM) Office for Community Health, the UNM Hos… Health literacy research and practice 2026-09-20 04:36:34 Source
Carotid intima-media thickness may be an early biomarker for cardiova… Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy · PMID 41026111 Épilepsie À vérifier Publication PubMed Voir la publication source To assess early signs of atherosclerosis following long-term treatment with the ketogenic diet therapy due to concerns… Epilepsia open 2026-09-20 04:36:33 Source
Impact of low-carbohydrate diet on health status: an umbrella review. Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy · PMID 39385794 Cancer À vérifier Publication PubMed Voir la publication source The prevalence of diet-related non-communicable diseases has increased. A low-carbohydrate diet (LCDs) is one of the mo… Frontiers in nutrition 2026-09-20 04:36:33 Source
The effect of anti-seizure medications on lipid values in adults with… Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy · PMID 37244221 Épilepsie À vérifier Publication PubMed Voir la publication source Certain anti-seizure medications (ASMs) adversely impact lipid values. Here, we explored the impact of ASMs on lipid va… Epilepsy & behavior : E&B 2026-09-20 04:36:33 Source
Possible role of locus coeruleus neuronal loss in age-related memory… The Role of the Locus Coeruleus in Age-related Distractibility · PMID 37694113 Maladie d’Alzheimer Immunomodulation Publication PubMed Voir la publication source Aging is associated with a decline in cognitive abilities, including memory and attention. It is generally accepted tha… Frontiers in neuroscience 2026-09-20 04:36:30 Source
Exploration — prudence

Pistes exploratoires 0

Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.

Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
Molécule / élément Maladie / population Objectif Phase / stade Statut / preuve Mécanisme / résumé Source Détail
Aucune piste exploratoire ne correspond aux filtres.