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Périmètre
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8666 résultats correspondants
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dans le périmètre Toutes les maladies
Niveau clinique
Études et traitements 4050
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| ISADER — Adduction and Infraspinatus Activity in Shoulder Pain NCT07765056 · NCT07765056 | Myopathies | Traitement symptomatique · Thérapie génique | Non applicable | COMPLETED | The goal of this randomized crossover trial is to determine whether differ… À vérifier | ClinicalTrials.gov 2026-08-16 12:59:23 | Détail |
| Prednisolone NCT05412394 · Once Weekly Infant Corticosteroid Trial for DMD | Myopathies | Immunomodulation · Thérapie génique | Phase 4 | RECRUITING | The goal of this clinical trial is to learn how different treatments affec… À vérifier | ClinicalTrials.gov 2026-08-16 12:59:23 | Détail |
| SAT-3247 NCT07287189 · BASECAMP — Phase 2 Study of SAT-3247 in Pediatric Ambulatory Patients | Myopathies | À vérifier | Phase 2 | RECRUITING | Phase 2a trial of SAT-3247 in ambulatory DMD patients aged ≥ 7 and \< 10 y… À vérifier | ClinicalTrials.gov 2026-08-16 12:59:23 | Détail |
| Telemonitoring for TMD-Related Pain NCT07764770 · NCT07764770 | Myopathies | Traitement symptomatique | Non applicable | COMPLETED | This prospective randomized clinical trial evaluates the effectiveness of… À vérifier | ClinicalTrials.gov 2026-08-16 12:59:23 | Détail |
| TMD-CPM — Endogenous Pain Inhibition Deficiency in Chronic TMD Pain NCT06617494 · NCT06617494 | Myopathies | Traitement symptomatique | À vérifier | RECRUITING | Temporomandibular disorders (TMDs) involve a range of conditions with vari… À vérifier | ClinicalTrials.gov 2026-08-16 12:59:23 | Détail |
| Trans-auricular Vagus Nerve Stimulation: High Intensity NCT07523113 · ME/CFS Brain Fog: Cognitive Rehabilitation Trial | Myopathies | À vérifier | Non applicable | RECRUITING | The purpose of this study is to compare two approaches to cognitive rehabi… À vérifier | ClinicalTrials.gov 2026-08-16 12:59:23 | Détail |
| Anifrolumab NCT05835310 · BLOSSOM — An Efficacy and Safety Study of Intravenous Anifrolumab to Treat Syste… | Lupus | À vérifier | Phase 3 | RECRUITING | This is an observational study, in which the main research question is to… À vérifier | ClinicalTrials.gov 2026-08-16 12:59:22 | Détail |
| AZD0120 NCT06897930 · A Study to Investigate the Safety, Tolerability, and Efficacy of AZD0120 in Adul… | Lupus | Immunomodulation · Thérapie cellulaire | Phase 1/2 | RECRUITING | This is a Phase 1b/2, single-arm, open-label, multi-center, clinical study… À vérifier | ClinicalTrials.gov 2026-08-16 12:59:22 | Détail |
| Litifilimab NCT05531565 · AMETHYST — A 2-Part Study to Learn Whether Litifilimab (BIIB059) Injections Can… | Lupus | Traitement symptomatique · Thérapie génique | Phase 2/3 | ACTIVE_NOT_RECRUITING | In this study, researchers will learn more about a study drug called litif… À vérifier | ClinicalTrials.gov 2026-08-16 12:59:22 | Détail |
| Focused Ultrasound for the Treatment of Pancreatic Cancer - an Intern… NCT05010226 · NCT05010226 | Cancer | À vérifier | À vérifier | NOT_YET_RECRUITING | The purpose of the registry is to collect data on the performance of the f… À vérifier | ClinicalTrials.gov 2026-08-16 12:59:21 | Détail |
| High Intensity Focused Ultrasound NCT01117246 · Pilot Study for Palliation of Pain in Bone Metastases by MR-HIFU | Cancer | Traitement symptomatique | Phase 1/2 | COMPLETED | This study is to confirm the safety and technical of MRI guided High Inten… À vérifier | ClinicalTrials.gov 2026-08-16 12:59:21 | Détail |
| High Intensity Focused Ultrasound NCT07757490 · SONAFUSION — Sonablate HIFU International Registry for PC & BPH Patients | Cancer | Traitement symptomatique | À vérifier | RECRUITING | This study is to confirm the safety and technical of MRI guided High Inten… À vérifier | ClinicalTrials.gov 2026-08-16 12:59:21 | Détail |
| Prospective Registry of Histotripsy for Soft Tissue Tumors NCT07470008 · NCT07470008 | Cancer | À vérifier | À vérifier | RECRUITING | Ultrasons focalisés produisant une cavitation contrôlée et une destruction… Dispositif/procédure : résultats à interpréter par essai et indication. | ClinicalTrials.gov 2026-08-16 12:59:21 | Détail |
| Ablation NCT03844399 · (3D) Ultrasound Imaging Liver and Kidney | Cancer | À vérifier | À vérifier | RECRUITING | This study involves the use of a medical device, the Creo Medical MicroBla… À vérifier | ClinicalTrials.gov 2026-08-16 12:59:20 | Détail |
| CT/US fusion NCT02687113 · Pre-procedure Planning for Radiofrequency Ablation Using CT or MR/US Fusion | Cancer | À vérifier | Non applicable | COMPLETED | The purpose of this study is to determine whether fusion technique of pre-… À vérifier | ClinicalTrials.gov 2026-08-16 12:59:20 | Détail |
| Debulking surgery NCT07273409 · PANTODON — Pancreatic Neuroendocrine Tumour - Optimal Surgical Debulking or Not | Cancer | Traitement symptomatique · Thérapie génique | Non applicable | RECRUITING | Pancreatic neuroendocrine tumours (pan-NETs) are neoplasms arising from th… À vérifier | ClinicalTrials.gov 2026-08-16 12:59:20 | Détail |
| Electrochemotherapy NCT02709811 · Safety and Feasibility of Electrochemotherapy in Unresectable Colorectal Adenoca… | Cancer | À vérifier | Phase 1/2 | TERMINATED | Electrochemotherapy (ECT) is a non-thermal tumour ablation modality. It co… À vérifier | ClinicalTrials.gov 2026-08-16 12:59:20 | Détail |
| EPIONE device NCT05651867 · EGLE — EPIONE Guided Lung Evaluation | Cancer | À vérifier | Non applicable | COMPLETED | Interventional clinical study to obtain performance and safety data of the… À vérifier | ClinicalTrials.gov 2026-08-16 12:59:20 | Détail |
| ExAblate 2000/2100 Magnetic Resonance-guided Focused Ultrasound (MRgF… NCT04123535 · HIFU-UPS — Focused Ultrasound to Promote Immune Responses for Undifferentiated P… | Cancer | À vérifier | Non applicable | TERMINATED | This study is a single site, single-arm, feasibility study to evaluate the… À vérifier | ClinicalTrials.gov 2026-08-16 12:59:20 | Détail |
| FocalOne NCT06375629 · ES-HIFU, Prospective Data Collection of Patients Treated With Partial Gland HIFU… | Cancer | À vérifier | À vérifier | TERMINATED | The objective of this study is to evaluate the clinical effectiveness and… À vérifier | ClinicalTrials.gov 2026-08-16 12:59:20 | Détail |
Découverte scientifique
Recherches et trouvailles 21
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Sclérose latérale amyotrophique | Neuroprotection · Immunomodulation | Découverte fondamentale | Exploratoire | Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… | Revue scientifique 2024-07-01 | Détail |
Bibliographie
Publications 4595
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Effects of testosterone-augmented multimodal exercise intervention in… Whole-body Electrical Muscle Stimulation Exercise · PMID 41988780 | Myasthénie | À vérifier | Publication | PubMed | Voir la publication source Spinal cord injury (SCI) leads to profound muscle atrophy, aerobic deconditioning, and metabolic dysfunction. Exercise-… | The Journal of clinical endocrinology and metabolism 2026-09-20 04:37:05 | Source |
| Feasibility and acceptability of whole-body electromyostimulation in… Whole-body Electrical Muscle Stimulation Exercise · PMID 42464389 | Myasthénie | À vérifier | Publication | PubMed | Voir la publication source Evidence on the effectiveness of electromyostimulation (EMS) has been reported in pulmonary rehabilitation, but the ben… | Pilot and feasibility studies 2026-09-20 04:37:05 | Source |
| Vestibular contributions adapt to the balance strategies adopted duri… Whole-body Electrical Muscle Stimulation Exercise · PMID 42616645 | Myasthénie | À vérifier | Publication | PubMed | Voir la publication source Vestibular contributions during walking are not uniform, but vary with gait phase, muscle group, and balance demands. M… | Journal of neurophysiology 2026-09-20 04:37:05 | Source |
| Clinical efficacy of abdominal moxibustion at the Zhongji (CV3) in co… Yangyin Roujin Decoction · PMID 42015783 | Myopathies | Neuroprotection · Traitement symptomatique | Publication | PubMed | Voir la publication source To investigate the clinical effect of abdominal moxibustion at the Zhongji (CV3) combined with Yiqi Tonglin Yangyin dec… | Journal of traditional Chinese medicine = Chung i tsa… 2026-09-20 04:37:03 | Source |
| Yiqi Huoxue Yangyin Decoction Ameliorates Diabetic Nephropathy by Tar… Yangyin Roujin Decoction · PMID 42713045 | Myopathies | À vérifier | Publication | PubMed | Voir la publication source This study aimed to investigate the protective effects and underlying mechanisms of Yiqi Huoxue Yangyin Decoction (YHY)… | Diabetes, metabolic syndrome and obesity : targets and… 2026-09-20 04:37:03 | Source |
| Yiqi Huoxue Yangyin Decoction attenuates diabetic nephropathy in mice… Yangyin Roujin Decoction · PMID 42016924 | Myopathies | Thérapie génique | Publication | PubMed | Voir la publication source Diabetic nephropathy (DN) is a major complication of diabetes with limited therapeutic options. Yiqi Huoxue Yangyin Dec… | Frontiers in pharmacology 2026-09-20 04:37:03 | Source |
| Barcoded oligonucleotide system (BOLT) for targeted organ delivery. Immunotherapy · PMID 42733790 | Cancer | À vérifier | Publication | PubMed | Voir la publication source The therapeutic potential of oligonucleotides (oligos) is limited by insufficient delivery to extrahepatic tissues. In… | Bioactive materials 2026-09-20 04:36:56 | Source |
| Dual metabolic checkpoint blockade a 3D-Printed metalloplatform remod… Immunotherapy · PMID 42724565 | Cancer | Immunomodulation | Publication | PubMed | Voir la publication source The immunosuppressive tumor microenvironment limits the efficacy of therapies that target metabolism. Here we show a st… | Bioactive materials 2026-09-20 04:36:56 | Source |
| Oligosaccharide adjuvant-deferred antigen endocytosis promotes cross-… Immunotherapy · PMID 42751513 | Cancer | Immunomodulation · Thérapie génique | Publication | PubMed | Voir la publication source Antigen cross-presentation by dendritic cells (DCs) is essential for inducing cytotoxic immune responses, which are cru… | Bioactive materials 2026-09-20 04:36:56 | Source |
| Feasibility and safety of early discharge after robot-assisted uro-on… Digital care pathway for hypertension · PMID 42671715 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source Early discharge after robot-assisted uro-oncologic surgery remains limited by concerns regarding patient safety and the… | Journal of robotic surgery 2026-09-20 04:36:49 | Source |
| HomeSafe: Postpartum Hypertensive Care Enabled by Electronic Health R… Digital care pathway for hypertension · PMID 41707683 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source The objective is to present stepwise refinements to , an Epic-tethered, population-health-coordinated postpartum pathwa… | American journal of perinatology 2026-09-20 04:36:49 | Source |
| Nutraceutical and functional food: efficacy against metabolic disorde… Digital care pathway for hypertension · PMID 42603698 | Hypertension artérielle | Neuroprotection · Immunomodulation | Publication | PubMed | Voir la publication source The growing global emphasis on health consciousness has significantly increased demand for traditional and complementar… | Journal of advanced research 2026-09-20 04:36:49 | Source |
| Community-engaged design of a virtual diabetes prevention program int… Asynchronous communication with nurse · PMID 42288862 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source The Diabetes Prevention Program (DPP) is an evidence-based approach to prevent Type 2 Diabetes (T2D), the leading cause… | BMC health services research 2026-09-20 04:36:48 | Source |
| Evolving Lung Cancer Navigator Practice Through Targeted Professional… Asynchronous communication with nurse · PMID 42463006 | Cancer | À vérifier | Publication | PubMed | Voir la publication source Lung cancer remains the leading cause of cancer deaths worldwide, and it has persistent disparities in detection, treat… | Chest 2026-09-20 04:36:48 | Source |
| Mass casualty training for prehospital and emergency providers in Kig… Asynchronous communication with nurse · PMID 42751142 | Hypertension artérielle | À vérifier | Publication | PubMed | Voir la publication source A mass casualty incident (MCI) occurs when the number of patients exceeds available healthcare resources, placing signi… | African journal of emergency medicine : Revue africain… 2026-09-20 04:36:48 | Source |
| Innovating a Teach-Back Model for Community Health Workers Led Health… Health Literacy Project · PMID 40194526 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source From 2021 to 2023, the City of Albuquerque, the University of New Mexico (UNM) Office for Community Health, the UNM Hos… | Health literacy research and practice 2026-09-20 04:36:34 | Source |
| Carotid intima-media thickness may be an early biomarker for cardiova… Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy · PMID 41026111 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source To assess early signs of atherosclerosis following long-term treatment with the ketogenic diet therapy due to concerns… | Epilepsia open 2026-09-20 04:36:33 | Source |
| Impact of low-carbohydrate diet on health status: an umbrella review. Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy · PMID 39385794 | Cancer | À vérifier | Publication | PubMed | Voir la publication source The prevalence of diet-related non-communicable diseases has increased. A low-carbohydrate diet (LCDs) is one of the mo… | Frontiers in nutrition 2026-09-20 04:36:33 | Source |
| The effect of anti-seizure medications on lipid values in adults with… Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy · PMID 37244221 | Épilepsie | À vérifier | Publication | PubMed | Voir la publication source Certain anti-seizure medications (ASMs) adversely impact lipid values. Here, we explored the impact of ASMs on lipid va… | Epilepsy & behavior : E&B 2026-09-20 04:36:33 | Source |
| Possible role of locus coeruleus neuronal loss in age-related memory… The Role of the Locus Coeruleus in Age-related Distractibility · PMID 37694113 | Maladie d’Alzheimer | Immunomodulation | Publication | PubMed | Voir la publication source Aging is associated with a decline in cognitive abilities, including memory and attention. It is generally accepted tha… | Frontiers in neuroscience 2026-09-20 04:36:30 | Source |
Exploration — prudence
Pistes exploratoires 0
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune piste exploratoire ne correspond aux filtres. | |||||||