Vue transversale de la maladie
Migraine
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
Périmètre
Filtrer toute la vue
Chaque choix s’applique immédiatement aux quatre sections. Le filtre « type de SEP » n’apparaît que lorsque la sclérose en plaques est sélectionnée.
1236 résultats correspondants
· 45 visibles sur cette page
dans le périmètre Migraine
Niveau clinique
Études et traitements 570
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| DFN-15 Active NCT03009019 · Efficacy, Tolerability, and Safety of DFN-15 | Migraine | À vérifier | Phase 3 | COMPLETED | Efficacy, Tolerability, and Safety of DFN-15 in episodic migraine with or… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:20 | Détail |
| DST — The Effect of Daylight Saving Time Transitions on Sleep and Mig… NCT05742191 · NCT05742191 | Migraine | À vérifier | À vérifier | UNKNOWN | A prospective study that investigates the impact of circadian rhythm distu… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:20 | Détail |
| Galcanezumab NCT03963232 · PERSIST — A Study of Galcanezumab (LY2951742) in Participants With Episodic Migr… | Migraine | À vérifier | Phase 3 | COMPLETED | The main purpose of this study is to evaluate the efficacy of the study dr… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:20 | Détail |
| Ketone for Migraine Prevention NCT05085483 · NCT05085483 | Migraine | À vérifier | Non applicable | COMPLETED | Efficacy of a nutritional ketogenic supplement (NKS) in reducing the numbe… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:20 | Détail |
| miR-155 Expression in Episodic and Chronic Migraine NCT05891808 · NCT05891808 | Migraine | Ralentissement de la progression · Immunomodulation · Traitement symptomatique… | À vérifier | UNKNOWN | Migraine is a common, yet often disabling, neurological disease that affec… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:20 | Détail |
| AMG334 NCT03927144 · Study of Sustained Benefit of AMG334 in Adult Episodic Migraine Patients | Migraine | À vérifier | Phase 4 | COMPLETED | The purpose of this study is to compare the sustained long-term benefit be… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:19 | Détail |
| Atogepant 60 mg NCT04740827 · ELEVATE — Atogepant for Prophylaxis of Migraine in Participants Who Failed Previ… | Migraine | À vérifier | Phase 3 | COMPLETED | This goal of this study is to compare three medications used for migraine… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:19 | Détail |
| CENSENMI — Presence of Signs of Central Sensitization in Episodic and… NCT05162664 · NCT05162664 | Migraine | À vérifier | Non applicable | COMPLETED | Nowadays migraine is conceptualized as a continuum, with at the one hand e… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:19 | Détail |
| Erenumab NCT04265755 · INTERROGATE — Biomarker and Genetic Predictors of Erenumab Treatment Response | Migraine | Traitement symptomatique | Phase 4 | COMPLETED | The primary objective of this study is to evaluate the treatment benefit o… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:19 | Détail |
| Galcanezumab NCT05127486 · CHALLENGE-MIG — A Study of Galcanezumab (LY2951742) in Adult Participants With E… | Migraine | À vérifier | Phase 4 | COMPLETED | The main purpose of this study is to evaluate the efficacy of the study dr… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:19 | Détail |
| greater occipital nerve block NCT06243874 · Comparison of Occipital Nerve and Sphenopalatine Ganglion Blockade | Migraine | Ralentissement de la progression · Traitement symptomatique | Non applicable | COMPLETED | Migraine is one of the most prevalent neurological disorders worldwide and… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:19 | Détail |
| MAbs NCT06562413 · SPHERA_WP1_2 — Searching for Novel Biological Phenotypes in Migraine Patients Re… | Migraine | Thérapie génique | À vérifier | RECRUITING | Aim of the study was to assess a potential dysfunction of the endocannabid… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:19 | Détail |
| MIGPHYSTREAT — Effectiveness of Multimodal Physical Therapy in Migrai… NCT05226559 · NCT05226559 | Migraine | Traitement symptomatique | Non applicable | UNKNOWN | INTRODUCTION: It is very common that migraine patients could refer neck pa… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:19 | Détail |
| Monoclonal antibody targeting the CGRP pathway (ligand or receptor) (… NCT06155123 · HD-EEG Connectivity Changes in Migraine Patients Undergoing Treatment With Anti-… | Migraine | Ralentissement de la progression | À vérifier | UNKNOWN | Migraine is a leading cause of disability with an estimated prevalence of… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:19 | Détail |
| Research Study to Determine Sensitivity to Gentle Touch and Pressure… NCT00329771 · NCT00329771 | Migraine | À vérifier | À vérifier | COMPLETED | Cutaneous allodynia (pronounced q-tane-ee-us all-o-din-ee-a) is common in… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:19 | Détail |
| The Effects of Vitamin D Plus Omega-3 Polyunsaturated Fatty Acids in… NCT05449145 · NCT05449145 | Migraine | Traitement symptomatique | Non applicable | UNKNOWN | First, the aims of this study are to explore the effect of vitamin D versu… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:19 | Détail |
| Valproate Sodium NCT04698525 · Comparative Study Between Valproate and Memantine in the Prophylactic Management… | Migraine | Thérapie génique | Phase 3 | COMPLETED | Migraine is one of the three most disabling diseases worldwide. Constitute… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:19 | Détail |
| Erenumab Dose 1 NCT03832998 · OASIS(CM) — Efficacy and Safety of Erenumab in Pediatric Subjects With Chronic M… | Migraine | À vérifier | Phase 3 | COMPLETED | This study will evaluate the efficacy and safety of erenumab in migraine p… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:17 | Détail |
| Fremanezumab NCT04464707 · A Study to Test if Fremanezumab is Effective in Preventing Chronic Migraine in P… | Migraine | À vérifier | Phase 3 | COMPLETED | The goal of this observational study is to compare, in real-world clinical… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:17 | Détail |
| Joint Cavity Injection NCT07347054 · Clinical Study of Myofascial Trigger Points(MTrPs) Injection in the Treatment of… | Migraine | Traitement symptomatique · Thérapie génique | Non applicable | RECRUITING | Chronic musculoskeletal pain (CMP) is a common disease in China, with a hi… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:17 | Détail |
Découverte scientifique
Recherches et trouvailles 0
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune trouvaille ne correspond aux filtres. | |||||||
Bibliographie
Publications 661
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Active machine learning model for the dynamic simulation and growth m… TI-001 · PMID 38184678 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Substrate-catalyzed growth offers a highly promising approach for the controlled synthesis of carbon nanostructures. Ho… | Nature communications 2026-08-08 00:59:56 | Source |
| Combined Occipital Nerve and Sphenopalatine Ganglion Neuromodulation… Occipital Nerve Stimulation · PMID 42100751 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Craniofacial complex regional pain syndrome (CRPS) is a rare, diagnostically challenging condition characterized by sym… | Local and regional anesthesia 2026-08-08 00:59:56 | Source |
| Comparative Efficacy and Acceptability of Noninvasive Brain Stimulati… Occipital Nerve Stimulation · PMID 42473074 | Migraine | À vérifier | Publication | PubMed | Voir la publication source This network meta-analysis (NMA) aimed to compare and rank the efficacy and acceptability of different noninvasive brai… | Brain and behavior 2026-08-08 00:59:56 | Source |
| TiO2 nanotubes: interdependence of substrate grain orientation and gr… TI-001 · PMID 25545715 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Highly ordered arrays of TiO2 nanotubes can be produced by self-organized anodic growth. It is desirable to identify ke… | ACS applied materials & interfaces 2026-08-08 00:59:56 | Source |
| International Headache society evidence-based guidelines on the use o… Nerivio Migra-1 Sham device · PMID 41117312 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source ObjectiveTo develop evidence-based clinical practice guidelines for non-invasive neuromodulation devices in acute and p… | Cephalalgia : an international journal of headache 2026-08-08 00:59:54 | Source |
| Plasma Phosphorylated Tau 217 in Participants at Risk for Chronic Tra… BE WELL With Migraine: Brain Education and WELLness With Migraine · PMID 42440317 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source In vivo biomarkers for detecting neuropathologies from repetitive head impacts (RHI), including chronic traumatic encep… | JAMA network open 2026-08-08 00:59:53 | Source |
| Weight loss with atogepant in the long-term treatment of migraine: An… BE WELL With Migraine: Brain Education and WELLness With Migraine · PMID 42396885 | Migraine | À vérifier | Publication | PubMed | Voir la publication source To assess weight loss with atogepant 60 mg once daily during long-term treatment of chronic migraine (CM) and episodic… | Headache 2026-08-08 00:59:53 | Source |
| Cellulose and Its Derivatives in Drug Delivery: Recent Advances and A… sumatriptan succinate · PMID 42198288 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Drug delivery systems have long faced a fundamental challenge: achieving high drug-loading efficiency, precise control… | Pharmaceutics 2026-08-08 00:59:51 | Source |
| Spatial metabolomics combined with MALDI-MSI unveils gut-brain axis m… sumatriptan succinate · PMID 41619552 | Migraine | Immunomodulation · Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Migraine is a highly disabling neurological disorder characterized by recurrent headaches and complex metabolic disturb… | Phytomedicine : international journal of phytotherapy… 2026-08-08 00:59:51 | Source |
| Drugs targeting nitric oxide synthase for migraine treatment. NXN-188 · PMID 24818644 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Ample evidence that nitric oxide (NO) is a causative molecule in migraine has encouraged research to develop drugs that… | Expert opinion on investigational drugs 2026-08-08 00:59:50 | Source |
| The nitric oxide synthase inhibitor and serotonin-receptor agonist NX… NXN-188 · PMID 29913885 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Background and aims NXN-188 is a combined neuronal nitric oxide synthase (nNOS) inhibitor and 5HT-1B/1D receptor agonis… | Scandinavian journal of pain 2026-08-08 00:59:50 | Source |
| Identifying central positional vertigo to prevent diagnostic pitfalls… Vestibular System in Migrainous Vertigo Patients · PMID 42564662 | Migraine | À vérifier | Publication | PubMed | Voir la publication source This case series highlights the critical role of radiological imaging in patients presenting with positional vertigo in… | Radiology case reports 2026-08-08 00:59:48 | Source |
| Quantitative pupillometry as a marker of autonomic dysregulation in v… Vestibular System in Migrainous Vertigo Patients · PMID 42548108 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source Vestibular migraine (VM) has been associated with altered central sensory processing; however, objective measures of au… | Journal of oral & facial pain and headache 2026-08-08 00:59:48 | Source |
| Arterial hepatic perfusion is preserved during early resuscitation af… blood withdrawal · PMID 42431156 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Hemorrhagic shock is a major contributor to morbidity and mortality after polytrauma and plays a central role in the de… | Injury 2026-08-08 00:59:47 | Source |
| Long peripheral catheters for short-term vascular access: A 7-day obs… blood withdrawal · PMID 42438309 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source Long peripheral catheters are increasingly used as an alternative to short peripheral catheters for short-term intraven… | The journal of vascular access 2026-08-08 00:59:47 | Source |
| A Real-World Evidence Study on US Patients Demonstrating Safety of Hi… Nerivio ® · PMID 41886224 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Remote electrical neuromodulation (REN) is an FDA-cleared, nonsignificant-risk, drug-free, prescribed wearable device (… | Pain and therapy 2026-08-08 00:59:45 | Source |
| Association of adverse childhood experiences with physical illness an… Brief Interventions in Chronic Migraine · PMID 40194777 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Adverse childhood experiences (ACEs) are highly prevalent and associated with life-long health consequences. Here, we i… | European journal of public health 2026-08-08 00:59:45 | Source |
| Non-Pharmacological Treatment of Primary Headaches-A Focused Review. Brief Interventions in Chronic Migraine · PMID 37891800 | Migraine | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Headache disorders are a significant global health burden, leading to reduced quality of life. While vast pharmacologic… | Brain sciences 2026-08-08 00:59:45 | Source |
| U.S. Veterans Using Remote Electrical Neuromodulation for Migraine: A… Nerivio ® · PMID 42520312 | Migraine | Ralentissement de la progression · Traitement symptomatique | Publication | PubMed | Voir la publication source Among U.S. veterans, migraine and other headache disorders are common, and frequently co-occur with other comorbidities… | Military medicine 2026-08-08 00:59:45 | Source |
| 2025 guideline update to acute treatment of migraine for adults in th… Greater Occipital Nerve Block with dexamethasone and lidocaine · PMID 41321235 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source To update the 2016 American Headache Society (AHS) guideline on parenteral pharmacologic therapies for the management o… | Headache 2026-08-08 00:59:43 | Source |
Exploration — prudence
Pistes exploratoires 5
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Bavisant BRAVEinMS — Bavisant | Migraine | Remyélinisation · Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Antagonisme du récepteur H3 de l’histamine Bavisant est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migra… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| Tol-MP Tol-MP — tolérance immunitaire spécifique de la myéline | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Microparticules biodégradables chargées en rapamycine et fonctionnalisées… Tol-MP est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migrain… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| SetPoint System SetPoint System — SetPoint Medical | Migraine | Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | re ApplicationsPublicationsCompanyCareersNewsGet startedGet startedNewsThe… SetPoint System est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation immunométabolique de la microglie 4-octyl itaconate et dérivés est étudié dans Sclérose latérale amyotrophique et documente plusieurs axes biologiques po… | Rapprochement Biomedical Watch · Sclérose latérale amy… | Détail |
| N-PPG N-PPG — modulation métabolique cérébrale | Migraine | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation métabolique et mitohormèse N-PPG est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être pertinents pour Migrai… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |