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Migraine
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
Périmètre
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1236 résultats correspondants
· 45 visibles sur cette page
dans le périmètre Migraine
Niveau clinique
Études et traitements 570
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| DFN-15 Active NCT03009019 · Efficacy, Tolerability, and Safety of DFN-15 | Migraine | À vérifier | Phase 3 | COMPLETED | Efficacy, Tolerability, and Safety of DFN-15 in episodic migraine with or… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:20 | Détail |
| DST — The Effect of Daylight Saving Time Transitions on Sleep and Mig… NCT05742191 · NCT05742191 | Migraine | À vérifier | À vérifier | UNKNOWN | A prospective study that investigates the impact of circadian rhythm distu… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:20 | Détail |
| Galcanezumab NCT03963232 · PERSIST — A Study of Galcanezumab (LY2951742) in Participants With Episodic Migr… | Migraine | À vérifier | Phase 3 | COMPLETED | The main purpose of this study is to evaluate the efficacy of the study dr… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:20 | Détail |
| Ketone for Migraine Prevention NCT05085483 · NCT05085483 | Migraine | À vérifier | Non applicable | COMPLETED | Efficacy of a nutritional ketogenic supplement (NKS) in reducing the numbe… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:20 | Détail |
| miR-155 Expression in Episodic and Chronic Migraine NCT05891808 · NCT05891808 | Migraine | Ralentissement de la progression · Immunomodulation · Traitement symptomatique… | À vérifier | UNKNOWN | Migraine is a common, yet often disabling, neurological disease that affec… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:20 | Détail |
| AMG334 NCT03927144 · Study of Sustained Benefit of AMG334 in Adult Episodic Migraine Patients | Migraine | À vérifier | Phase 4 | COMPLETED | The purpose of this study is to compare the sustained long-term benefit be… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:19 | Détail |
| Atogepant 60 mg NCT04740827 · ELEVATE — Atogepant for Prophylaxis of Migraine in Participants Who Failed Previ… | Migraine | À vérifier | Phase 3 | COMPLETED | This goal of this study is to compare three medications used for migraine… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:19 | Détail |
| CENSENMI — Presence of Signs of Central Sensitization in Episodic and… NCT05162664 · NCT05162664 | Migraine | À vérifier | Non applicable | COMPLETED | Nowadays migraine is conceptualized as a continuum, with at the one hand e… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:19 | Détail |
| Erenumab NCT04265755 · INTERROGATE — Biomarker and Genetic Predictors of Erenumab Treatment Response | Migraine | Traitement symptomatique | Phase 4 | COMPLETED | The primary objective of this study is to evaluate the treatment benefit o… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:19 | Détail |
| Galcanezumab NCT05127486 · CHALLENGE-MIG — A Study of Galcanezumab (LY2951742) in Adult Participants With E… | Migraine | À vérifier | Phase 4 | COMPLETED | The main purpose of this study is to evaluate the efficacy of the study dr… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:19 | Détail |
| greater occipital nerve block NCT06243874 · Comparison of Occipital Nerve and Sphenopalatine Ganglion Blockade | Migraine | Ralentissement de la progression · Traitement symptomatique | Non applicable | COMPLETED | Migraine is one of the most prevalent neurological disorders worldwide and… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:19 | Détail |
| MAbs NCT06562413 · SPHERA_WP1_2 — Searching for Novel Biological Phenotypes in Migraine Patients Re… | Migraine | Thérapie génique | À vérifier | RECRUITING | Aim of the study was to assess a potential dysfunction of the endocannabid… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:19 | Détail |
| MIGPHYSTREAT — Effectiveness of Multimodal Physical Therapy in Migrai… NCT05226559 · NCT05226559 | Migraine | Traitement symptomatique | Non applicable | UNKNOWN | INTRODUCTION: It is very common that migraine patients could refer neck pa… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:19 | Détail |
| Monoclonal antibody targeting the CGRP pathway (ligand or receptor) (… NCT06155123 · HD-EEG Connectivity Changes in Migraine Patients Undergoing Treatment With Anti-… | Migraine | Ralentissement de la progression | À vérifier | UNKNOWN | Migraine is a leading cause of disability with an estimated prevalence of… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:19 | Détail |
| Research Study to Determine Sensitivity to Gentle Touch and Pressure… NCT00329771 · NCT00329771 | Migraine | À vérifier | À vérifier | COMPLETED | Cutaneous allodynia (pronounced q-tane-ee-us all-o-din-ee-a) is common in… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:19 | Détail |
| The Effects of Vitamin D Plus Omega-3 Polyunsaturated Fatty Acids in… NCT05449145 · NCT05449145 | Migraine | Traitement symptomatique | Non applicable | UNKNOWN | First, the aims of this study are to explore the effect of vitamin D versu… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:19 | Détail |
| Valproate Sodium NCT04698525 · Comparative Study Between Valproate and Memantine in the Prophylactic Management… | Migraine | Thérapie génique | Phase 3 | COMPLETED | Migraine is one of the three most disabling diseases worldwide. Constitute… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:19 | Détail |
| Erenumab Dose 1 NCT03832998 · OASIS(CM) — Efficacy and Safety of Erenumab in Pediatric Subjects With Chronic M… | Migraine | À vérifier | Phase 3 | COMPLETED | This study will evaluate the efficacy and safety of erenumab in migraine p… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:17 | Détail |
| Fremanezumab NCT04464707 · A Study to Test if Fremanezumab is Effective in Preventing Chronic Migraine in P… | Migraine | À vérifier | Phase 3 | COMPLETED | The goal of this observational study is to compare, in real-world clinical… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:17 | Détail |
| Joint Cavity Injection NCT07347054 · Clinical Study of Myofascial Trigger Points(MTrPs) Injection in the Treatment of… | Migraine | Traitement symptomatique · Thérapie génique | Non applicable | RECRUITING | Chronic musculoskeletal pain (CMP) is a common disease in China, with a hi… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:17 | Détail |
Découverte scientifique
Recherches et trouvailles 0
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune trouvaille ne correspond aux filtres. | |||||||
Bibliographie
Publications 661
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Retrospective study on affecting factors and predictive model for gui… PFO occlusion · PMID 41630323 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Patent foramen ovale (PFO) is a common congenital cardiac anomaly. Transcatheter closure is effective, but guidewire pa… | Medicine 2026-08-16 13:11:54 | Source |
| Increased morning cortisol after ketamine treatment for suicidal depr… ketamine infusion · PMID 42349524 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Depression and its severe outcomes, suicidal ideation and behavior, are exacerbated by stress. A broad literature links… | Journal of affective disorders 2026-08-16 13:11:50 | Source |
| Peri-operative opioid analgesic requirements in dogs undergoing hemil… ketamine infusion · PMID 42061330 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Résumé non disponible dans la base locale. | Research in veterinary science 2026-08-16 13:11:50 | Source |
| Safety and Efficacy of the Prescribing Practices of Ketamine for Pain… ketamine infusion · PMID 41546137 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Ketamine has analgesic and sedative properties that are thought to reduce opioid tolerance and opioid-induced hyperalge… | The Annals of pharmacotherapy 2026-08-16 13:11:50 | Source |
| Acute stress alters prefrontal resting-state networks and tES restore… Transcranial electrical stimulation · PMID 42142754 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Acute stress is known to alter resting-state brain connectivity. However, the specific effects on prefrontal networks a… | Journal of affective disorders 2026-08-16 13:11:46 | Source |
| Multimodal intraoperative monitoring of facial nerve function: combin… Transcranial electrical stimulation · PMID 42407405 | Migraine | À vérifier | Publication | PubMed | Voir la publication source To compare the intraoperative blink reflex (BR) and facial corticobulbar motor evoked potentials (FCoMEPs) in skull bas… | Clinical neurophysiology : official journal of the Int… 2026-08-16 13:11:46 | Source |
| Combination Pharmacotherapies for Obesity-Current Evidence and Future… Amylin · PMID 42581493 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Conventional single-agent drugs yield modest, plateauing weight loss and often lead to weight regain. Combination pharm… | Endocrinology, diabetes & metabolism 2026-08-16 13:11:45 | Source |
| Shared pathophysiology and therapeutic repurposing in Alzheimer's dis… Amylin · PMID 42247872 | Migraine | Neuroprotection | Publication | PubMed | Voir la publication source Alzheimer's disease (AD) and type 2 diabetes mellitus (T2DM) are two prevalent age-related disorders that share strikin… | Bioorganic chemistry 2026-08-16 13:11:45 | Source |
| Heterogeneity in the efficacy of bosentan for hypertensive nephropath… Endothelin-1 · PMID 41649882 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Many patients with hypertensive nephropathy progress to chronic kidney disease (CKD). Targeting the core pathophysiolog… | Annals of medicine 2026-08-16 13:11:44 | Source |
| Serum endothelin-1 and endothelin-2 levels in healthy controls and ci… Endothelin-1 · PMID 41774498 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source The aim of this study was to evaluate serum endothelin-1 (ET-1) and endothelin-2 (ET-2) levels in patients with dipper… | Clinical and experimental hypertension (New York, N.Y.… 2026-08-16 13:11:44 | Source |
| The correlation between serum endothelin-1 levels and aortic stiffnes… Endothelin-1 · PMID 41820016 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Increased aortic stiffness (AS) is a recognized predictor of cardiovascular morbidity and mortality in patients with ch… | Renal failure 2026-08-16 13:11:44 | Source |
| Cilostazol in a Child With Moyamoya Disease. Cilostazol · PMID 41505343 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source Moyamoya disease is characterized by progressive stenosis of the terminal internal carotid arteries and their branches… | Journal of child neurology 2026-08-16 13:11:43 | Source |
| Prognostic implications of single antiplatelet therapy in individuals… Cilostazol · PMID 41981998 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Antiplatelet therapy is recommended for secondary prevention in patients with diabetes and peripheral arterial disease… | Annals of medicine 2026-08-16 13:11:43 | Source |
| Secondary prevention strategies for patients with lower extremity per… Cilostazol · PMID 42069036 | Migraine | Ralentissement de la progression · Traitement symptomatique | Publication | PubMed | Voir la publication source Individuals with lower extremity peripheral artery disease (LE PAD) represent a subset of patients with atherosclerotic… | American heart journal 2026-08-16 13:11:43 | Source |
| Antiseizure Medications that Did Not Reach the Epilepsy Market: An As… Tonabersat · PMID 41764707 | Migraine | À vérifier | Publication | PubMed | Voir la publication source The EILAT Conferences on New Antiepileptic Drugs (AEDs), which have taken place biennially since 1992, have traditional… | Drugs 2026-08-16 13:11:37 | Source |
| Migraine with visual aura, unilateral mydriasis and Takotsubo Syndrom… HYPOTHAMIG — Hypothalamus Connectivity in Chronic and Episodic Migraine · PMID 42597549 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source The recent examination of a woman who presented a migraine attack with visual aura and unilateral mydriasis, followed,… | Frontiers in neurology 2026-08-16 13:11:30 | Source |
| Diagnosis and management of migraine in adults: a population-based st… Triptan · PMID 41513289 | Migraine | Immunomodulation · Thérapie génique | Publication | PubMed | Voir la publication source Previous work has highlighted that migraine is underdiagnosed and undertreated in primary care. To characterise diagnos… | BJGP open 2026-08-16 13:11:29 | Source |
| Prescription practices and reasons for referral to tertiary care amon… Triptan · PMID 42247799 | Migraine | À vérifier | Publication | PubMed | Voir la publication source To evaluate prescription patterns, referral reasons, patient profiles, diagnostic accuracy, treatment adequacy, and sat… | Journal of clinical neuroscience : official journal of… 2026-08-16 13:11:29 | Source |
| Stroke in combined hormonal contraceptive users treated with triptans. Triptan · PMID 41932373 | Migraine | À vérifier | Publication | PubMed | Voir la publication source The extent of triptan use among users of combined hormonal contraceptives (CHC) is unknown. Likewise, it is unclear whe… | Contraception 2026-08-16 13:11:29 | Source |
| Elucidation of a novel fungal biotransformation pathway of ibuprofen… Non-steroidal anti-inflammatory drug (NSAID) · PMID 42251002 | Migraine | Immunomodulation | Publication | PubMed | Voir la publication source Ibuprofen, a widely used non-steroidal anti-inflammatory drug (NSAID), has been detected in the environment and is know… | Journal of bioscience and bioengineering 2026-08-16 13:11:28 | Source |
Exploration — prudence
Pistes exploratoires 5
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Bavisant BRAVEinMS — Bavisant | Migraine | Remyélinisation · Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Antagonisme du récepteur H3 de l’histamine Bavisant est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migra… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| Tol-MP Tol-MP — tolérance immunitaire spécifique de la myéline | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Microparticules biodégradables chargées en rapamycine et fonctionnalisées… Tol-MP est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migrain… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| SetPoint System SetPoint System — SetPoint Medical | Migraine | Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | re ApplicationsPublicationsCompanyCareersNewsGet startedGet startedNewsThe… SetPoint System est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation immunométabolique de la microglie 4-octyl itaconate et dérivés est étudié dans Sclérose latérale amyotrophique et documente plusieurs axes biologiques po… | Rapprochement Biomedical Watch · Sclérose latérale amy… | Détail |
| N-PPG N-PPG — modulation métabolique cérébrale | Migraine | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation métabolique et mitohormèse N-PPG est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être pertinents pour Migrai… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |