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Migraine
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
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1236 résultats correspondants
· 45 visibles sur cette page
dans le périmètre Migraine
Niveau clinique
Études et traitements 570
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| DFN-15 Active NCT03009019 · Efficacy, Tolerability, and Safety of DFN-15 | Migraine | À vérifier | Phase 3 | COMPLETED | Efficacy, Tolerability, and Safety of DFN-15 in episodic migraine with or… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:20 | Détail |
| DST — The Effect of Daylight Saving Time Transitions on Sleep and Mig… NCT05742191 · NCT05742191 | Migraine | À vérifier | À vérifier | UNKNOWN | A prospective study that investigates the impact of circadian rhythm distu… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:20 | Détail |
| Galcanezumab NCT03963232 · PERSIST — A Study of Galcanezumab (LY2951742) in Participants With Episodic Migr… | Migraine | À vérifier | Phase 3 | COMPLETED | The main purpose of this study is to evaluate the efficacy of the study dr… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:20 | Détail |
| Ketone for Migraine Prevention NCT05085483 · NCT05085483 | Migraine | À vérifier | Non applicable | COMPLETED | Efficacy of a nutritional ketogenic supplement (NKS) in reducing the numbe… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:20 | Détail |
| miR-155 Expression in Episodic and Chronic Migraine NCT05891808 · NCT05891808 | Migraine | Ralentissement de la progression · Immunomodulation · Traitement symptomatique… | À vérifier | UNKNOWN | Migraine is a common, yet often disabling, neurological disease that affec… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:20 | Détail |
| AMG334 NCT03927144 · Study of Sustained Benefit of AMG334 in Adult Episodic Migraine Patients | Migraine | À vérifier | Phase 4 | COMPLETED | The purpose of this study is to compare the sustained long-term benefit be… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:19 | Détail |
| Atogepant 60 mg NCT04740827 · ELEVATE — Atogepant for Prophylaxis of Migraine in Participants Who Failed Previ… | Migraine | À vérifier | Phase 3 | COMPLETED | This goal of this study is to compare three medications used for migraine… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:19 | Détail |
| CENSENMI — Presence of Signs of Central Sensitization in Episodic and… NCT05162664 · NCT05162664 | Migraine | À vérifier | Non applicable | COMPLETED | Nowadays migraine is conceptualized as a continuum, with at the one hand e… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:19 | Détail |
| Erenumab NCT04265755 · INTERROGATE — Biomarker and Genetic Predictors of Erenumab Treatment Response | Migraine | Traitement symptomatique | Phase 4 | COMPLETED | The primary objective of this study is to evaluate the treatment benefit o… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:19 | Détail |
| Galcanezumab NCT05127486 · CHALLENGE-MIG — A Study of Galcanezumab (LY2951742) in Adult Participants With E… | Migraine | À vérifier | Phase 4 | COMPLETED | The main purpose of this study is to evaluate the efficacy of the study dr… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:19 | Détail |
| greater occipital nerve block NCT06243874 · Comparison of Occipital Nerve and Sphenopalatine Ganglion Blockade | Migraine | Ralentissement de la progression · Traitement symptomatique | Non applicable | COMPLETED | Migraine is one of the most prevalent neurological disorders worldwide and… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:19 | Détail |
| MAbs NCT06562413 · SPHERA_WP1_2 — Searching for Novel Biological Phenotypes in Migraine Patients Re… | Migraine | Thérapie génique | À vérifier | RECRUITING | Aim of the study was to assess a potential dysfunction of the endocannabid… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:19 | Détail |
| MIGPHYSTREAT — Effectiveness of Multimodal Physical Therapy in Migrai… NCT05226559 · NCT05226559 | Migraine | Traitement symptomatique | Non applicable | UNKNOWN | INTRODUCTION: It is very common that migraine patients could refer neck pa… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:19 | Détail |
| Monoclonal antibody targeting the CGRP pathway (ligand or receptor) (… NCT06155123 · HD-EEG Connectivity Changes in Migraine Patients Undergoing Treatment With Anti-… | Migraine | Ralentissement de la progression | À vérifier | UNKNOWN | Migraine is a leading cause of disability with an estimated prevalence of… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:19 | Détail |
| Research Study to Determine Sensitivity to Gentle Touch and Pressure… NCT00329771 · NCT00329771 | Migraine | À vérifier | À vérifier | COMPLETED | Cutaneous allodynia (pronounced q-tane-ee-us all-o-din-ee-a) is common in… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:19 | Détail |
| The Effects of Vitamin D Plus Omega-3 Polyunsaturated Fatty Acids in… NCT05449145 · NCT05449145 | Migraine | Traitement symptomatique | Non applicable | UNKNOWN | First, the aims of this study are to explore the effect of vitamin D versu… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:19 | Détail |
| Valproate Sodium NCT04698525 · Comparative Study Between Valproate and Memantine in the Prophylactic Management… | Migraine | Thérapie génique | Phase 3 | COMPLETED | Migraine is one of the three most disabling diseases worldwide. Constitute… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:19 | Détail |
| Erenumab Dose 1 NCT03832998 · OASIS(CM) — Efficacy and Safety of Erenumab in Pediatric Subjects With Chronic M… | Migraine | À vérifier | Phase 3 | COMPLETED | This study will evaluate the efficacy and safety of erenumab in migraine p… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:17 | Détail |
| Fremanezumab NCT04464707 · A Study to Test if Fremanezumab is Effective in Preventing Chronic Migraine in P… | Migraine | À vérifier | Phase 3 | COMPLETED | The goal of this observational study is to compare, in real-world clinical… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:17 | Détail |
| Joint Cavity Injection NCT07347054 · Clinical Study of Myofascial Trigger Points(MTrPs) Injection in the Treatment of… | Migraine | Traitement symptomatique · Thérapie génique | Non applicable | RECRUITING | Chronic musculoskeletal pain (CMP) is a common disease in China, with a hi… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:17 | Détail |
Découverte scientifique
Recherches et trouvailles 0
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune trouvaille ne correspond aux filtres. | |||||||
Bibliographie
Publications 661
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Case Report: Anodal DLPFC-tDCS for refractory post-traumatic cognitiv… Galcanezumab · PMID 42602261 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Cognitive fatigue is among the most common and disabling long-term sequelae of mild traumatic brain injury (mTBI), with… | Frontiers in human neuroscience 2026-08-16 19:23:06 | Source |
| High Cervical 10 kHz Spinal Cord Stimulation After Occipital Nerve St… Occipital Nerve Stimulation · PMID 42573543 | Migraine | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source In this retrospective study, we evaluated high-frequency spinal cord stimulation (SCS) as an alternative neuromodulatio… | Neuromodulation : journal of the International Neuromo… 2026-08-16 19:23:03 | Source |
| Global prevalence and disability burden of brain disorders: Impact of… BE WELL With Migraine: Brain Education and WELLness With Migraine · PMID 42269957 | Migraine | Ralentissement de la progression | Publication | PubMed | Voir la publication source Brain disorders-encompassing neurological, mental, and substance use disorders-account for 10 of the top 25 causes of d… | Neuroscience and biobehavioral reviews 2026-08-16 19:22:56 | Source |
| NXN-188, a selective nNOS inhibitor and a 5-HT1B/1D receptor agonist,… NXN-188 · PMID 23155193 | Migraine | À vérifier | Publication | PubMed | Voir la publication source NXN-188 is a combined neuronal nitric oxide synthase (nNOS) inhibitor and 5-hydroxytryptamine 1B/1D (5-HT1B/1D) recepto… | Cephalalgia : an international journal of headache 2026-08-16 19:22:51 | Source |
| Vestibular cortex-related effective connectivity signatures: characte… Vestibular System in Migrainous Vertigo Patients · PMID 42337425 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Neuroimaging studies of vestibular migraine (VM) have revealed abnormal functional connectivity in the central vestibul… | The journal of headache and pain 2026-08-16 19:22:46 | Source |
| Cultured Epidermal Autograft Formation With Reduced Platelet-Rich Pla… blood withdrawal · PMID 42424623 | Migraine | Immunomodulation | Publication | PubMed | Voir la publication source Cultured epidermal autografts (CEA) reportedly have better cosmesis than traditional autografts and are especially usef… | The Journal of craniofacial surgery 2026-08-16 19:22:45 | Source |
| Impact of acute high thoracic spinal cord injury on in vivo vascular… blood withdrawal · PMID 42219075 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Cardiovascular dysfunction is a major cause of morbidity and mortality following high-thoracic spinal cord injury (SCI)… | Experimental neurology 2026-08-16 19:22:45 | Source |
| Practice-Based Consensus Amongst Indian Neurologists: Adopting Remote… Nerivio ® · PMID 41697517 | Migraine | Ralentissement de la progression | Publication | PubMed | Voir la publication source Migraine is a major cause of disability in India, disproportionately affecting women and adolescents. Although traditio… | Advances in therapy 2026-08-16 19:22:41 | Source |
| Ultrasound-guided 5-in-1 trigger point injection for treating tension… Greater Occipital Nerve Block with 0.9% saline · PMID 35945722 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Tension-type headache (TTH) is the most common type of primary headache, and trigger point injection (TPI) is frequentl… | Medicine 2026-08-16 19:22:37 | Source |
| The consequences of the new European reclassification of non-invasive… tDCS device from neuroConn · PMID 38679530 | Migraine | À vérifier | Publication | PubMed | Voir la publication source A significant amount of European basic and clinical neuroscience research includes the use of transcranial magnetic sti… | Clinical neurophysiology : official journal of the Int… 2026-08-16 19:22:35 | Source |
| Prescription of cardiovascular drugs in the French ODIN cohort of hea… Part A: TRV250-20mg/ml · PMID 24388162 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Chronic heart failure (CHF) is a frequent severe disease. Disease-management programmes, which contain a therapeutic pa… | Archives of cardiovascular diseases 2026-08-16 19:22:24 | Source |
| Socioeconomic factors and mortality in diastolic heart failure. Part A: TRV250-20mg/ml · PMID 24467732 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Mortality in patients with heart failure with preserved ejection fraction (HFPEF) has remained stable over recent decad… | European journal of clinical investigation 2026-08-16 19:22:24 | Source |
| [Neurostimulation of the supraorbital nerve with the Cefaly device -… Cefaly device · PMID 31089108 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source Treatment of migraine mainly includes pharmacological approaches aimed at breaking migraine attacks and preventive trea… | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 2026-08-16 19:22:19 | Source |
| Management of refractory chronic migraine using ultrasound-guided pul… Efficacy of Greater Occipital Nerve Radiofrequency for Refractory Migraine Treatment · PMID 30… | Migraine | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Although various oral medications and procedures are applied for managing migraine, their efficacy remains limited. To… | Medicine 2026-08-16 19:22:18 | Source |
| Comparative efficacy, quality of life, safety, and tolerability of at… Rimegepant/BHV3000 · PMID 38410850 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Comparative evaluations of preventive migraine treatments can help inform clinical decision making for managing migrain… | Cephalalgia : an international journal of headache 2026-08-16 19:22:17 | Source |
| Cost per treatment responder analysis of atogepant compared to rimege… Rimegepant/BHV3000 · PMID 39248007 | Migraine | À vérifier | Publication | PubMed | Voir la publication source To estimate the number needed to treat and cost per additional responder for atogepant and rimegepant versus placebo fo… | Headache 2026-08-16 19:22:17 | Source |
| Pharmacological interventions for antipsychotic-induced weight gain i… Topiramate 100 mg · PMID 38878592 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Antipsychotic-induced weight gain (AIWG) is a significant but frequently neglected adverse effect of first- and second-… | General hospital psychiatry 2026-08-16 19:22:16 | Source |
| Propranolol Versus Metoprolol for Treatment of Electrical Storm in Pa… Propranolol 160 mg · PMID 29699616 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Electrical storm (ES), characterized by unrelenting recurrences of ventricular arrhythmias, is observed in approximatel… | Journal of the American College of Cardiology 2026-08-16 19:22:16 | Source |
| Tolerability, safety, and efficacy of atogepant versus topiramate in… Atogepant 60 mg · PMID 42492556 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Oral calcitonin gene-related peptide (CGRP) receptor antagonists such as atogepant have been approved for preventive tr… | The Lancet. Neurology 2026-08-16 19:22:14 | Source |
| Encephalopathy following subcutaneous administration of Brixadi® exte… Fentanyl · PMID 42571226 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Long-acting injectable buprenorphine is one option for the management of opioid use disorder. The United States Food an… | Toxicology reports 2026-08-16 19:22:13 | Source |
Exploration — prudence
Pistes exploratoires 5
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Bavisant BRAVEinMS — Bavisant | Migraine | Remyélinisation · Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Antagonisme du récepteur H3 de l’histamine Bavisant est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migra… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| Tol-MP Tol-MP — tolérance immunitaire spécifique de la myéline | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Microparticules biodégradables chargées en rapamycine et fonctionnalisées… Tol-MP est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migrain… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| SetPoint System SetPoint System — SetPoint Medical | Migraine | Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | re ApplicationsPublicationsCompanyCareersNewsGet startedGet startedNewsThe… SetPoint System est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation immunométabolique de la microglie 4-octyl itaconate et dérivés est étudié dans Sclérose latérale amyotrophique et documente plusieurs axes biologiques po… | Rapprochement Biomedical Watch · Sclérose latérale amy… | Détail |
| N-PPG N-PPG — modulation métabolique cérébrale | Migraine | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation métabolique et mitohormèse N-PPG est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être pertinents pour Migrai… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |