Vue transversale de la maladie
Migraine
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
Périmètre
Filtrer toute la vue
Chaque choix s’applique immédiatement aux quatre sections. Le filtre « type de SEP » n’apparaît que lorsque la sclérose en plaques est sélectionnée.
1236 résultats correspondants
· 45 visibles sur cette page
dans le périmètre Migraine
Niveau clinique
Études et traitements 570
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| DFN-15 Active NCT03009019 · Efficacy, Tolerability, and Safety of DFN-15 | Migraine | À vérifier | Phase 3 | COMPLETED | Efficacy, Tolerability, and Safety of DFN-15 in episodic migraine with or… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:20 | Détail |
| DST — The Effect of Daylight Saving Time Transitions on Sleep and Mig… NCT05742191 · NCT05742191 | Migraine | À vérifier | À vérifier | UNKNOWN | A prospective study that investigates the impact of circadian rhythm distu… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:20 | Détail |
| Galcanezumab NCT03963232 · PERSIST — A Study of Galcanezumab (LY2951742) in Participants With Episodic Migr… | Migraine | À vérifier | Phase 3 | COMPLETED | The main purpose of this study is to evaluate the efficacy of the study dr… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:20 | Détail |
| Ketone for Migraine Prevention NCT05085483 · NCT05085483 | Migraine | À vérifier | Non applicable | COMPLETED | Efficacy of a nutritional ketogenic supplement (NKS) in reducing the numbe… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:20 | Détail |
| miR-155 Expression in Episodic and Chronic Migraine NCT05891808 · NCT05891808 | Migraine | Ralentissement de la progression · Immunomodulation · Traitement symptomatique… | À vérifier | UNKNOWN | Migraine is a common, yet often disabling, neurological disease that affec… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:20 | Détail |
| AMG334 NCT03927144 · Study of Sustained Benefit of AMG334 in Adult Episodic Migraine Patients | Migraine | À vérifier | Phase 4 | COMPLETED | The purpose of this study is to compare the sustained long-term benefit be… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:19 | Détail |
| Atogepant 60 mg NCT04740827 · ELEVATE — Atogepant for Prophylaxis of Migraine in Participants Who Failed Previ… | Migraine | À vérifier | Phase 3 | COMPLETED | This goal of this study is to compare three medications used for migraine… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:19 | Détail |
| CENSENMI — Presence of Signs of Central Sensitization in Episodic and… NCT05162664 · NCT05162664 | Migraine | À vérifier | Non applicable | COMPLETED | Nowadays migraine is conceptualized as a continuum, with at the one hand e… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:19 | Détail |
| Erenumab NCT04265755 · INTERROGATE — Biomarker and Genetic Predictors of Erenumab Treatment Response | Migraine | Traitement symptomatique | Phase 4 | COMPLETED | The primary objective of this study is to evaluate the treatment benefit o… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:19 | Détail |
| Galcanezumab NCT05127486 · CHALLENGE-MIG — A Study of Galcanezumab (LY2951742) in Adult Participants With E… | Migraine | À vérifier | Phase 4 | COMPLETED | The main purpose of this study is to evaluate the efficacy of the study dr… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:19 | Détail |
| greater occipital nerve block NCT06243874 · Comparison of Occipital Nerve and Sphenopalatine Ganglion Blockade | Migraine | Ralentissement de la progression · Traitement symptomatique | Non applicable | COMPLETED | Migraine is one of the most prevalent neurological disorders worldwide and… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:19 | Détail |
| MAbs NCT06562413 · SPHERA_WP1_2 — Searching for Novel Biological Phenotypes in Migraine Patients Re… | Migraine | Thérapie génique | À vérifier | RECRUITING | Aim of the study was to assess a potential dysfunction of the endocannabid… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:19 | Détail |
| MIGPHYSTREAT — Effectiveness of Multimodal Physical Therapy in Migrai… NCT05226559 · NCT05226559 | Migraine | Traitement symptomatique | Non applicable | UNKNOWN | INTRODUCTION: It is very common that migraine patients could refer neck pa… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:19 | Détail |
| Monoclonal antibody targeting the CGRP pathway (ligand or receptor) (… NCT06155123 · HD-EEG Connectivity Changes in Migraine Patients Undergoing Treatment With Anti-… | Migraine | Ralentissement de la progression | À vérifier | UNKNOWN | Migraine is a leading cause of disability with an estimated prevalence of… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:19 | Détail |
| Research Study to Determine Sensitivity to Gentle Touch and Pressure… NCT00329771 · NCT00329771 | Migraine | À vérifier | À vérifier | COMPLETED | Cutaneous allodynia (pronounced q-tane-ee-us all-o-din-ee-a) is common in… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:19 | Détail |
| The Effects of Vitamin D Plus Omega-3 Polyunsaturated Fatty Acids in… NCT05449145 · NCT05449145 | Migraine | Traitement symptomatique | Non applicable | UNKNOWN | First, the aims of this study are to explore the effect of vitamin D versu… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:19 | Détail |
| Valproate Sodium NCT04698525 · Comparative Study Between Valproate and Memantine in the Prophylactic Management… | Migraine | Thérapie génique | Phase 3 | COMPLETED | Migraine is one of the three most disabling diseases worldwide. Constitute… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:19 | Détail |
| Erenumab Dose 1 NCT03832998 · OASIS(CM) — Efficacy and Safety of Erenumab in Pediatric Subjects With Chronic M… | Migraine | À vérifier | Phase 3 | COMPLETED | This study will evaluate the efficacy and safety of erenumab in migraine p… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:17 | Détail |
| Fremanezumab NCT04464707 · A Study to Test if Fremanezumab is Effective in Preventing Chronic Migraine in P… | Migraine | À vérifier | Phase 3 | COMPLETED | The goal of this observational study is to compare, in real-world clinical… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:17 | Détail |
| Joint Cavity Injection NCT07347054 · Clinical Study of Myofascial Trigger Points(MTrPs) Injection in the Treatment of… | Migraine | Traitement symptomatique · Thérapie génique | Non applicable | RECRUITING | Chronic musculoskeletal pain (CMP) is a common disease in China, with a hi… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:17 | Détail |
Découverte scientifique
Recherches et trouvailles 0
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune trouvaille ne correspond aux filtres. | |||||||
Bibliographie
Publications 661
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Comparison of choroidal biomarkers and scleral thickness in keratocon… Optical Coherence Tomography (OCT) - Heidelberg SPECTRALIS HRA+OCT · PMID 42029908 | Migraine | À vérifier | Publication | PubMed | Voir la publication source PURPOSE: To investigate whether corneal collagen cross-linking (CXL) is associated with measurable remodeling of extra-… | Graefe's archive for clinical and experimental ophthal… 2026-08-16 19:24:04 | Source |
| Real-Time High-Resolution OCT for Imaging Retinal and Choroidal Blood… Optical Coherence Tomography (OCT) - Heidelberg SPECTRALIS HRA+OCT · PMID 42200766 | Migraine | À vérifier | Publication | PubMed | Voir la publication source To evaluate the feasibility of visualizing intravascular moving particles within retinal and choroidal vessels using re… | Investigative ophthalmology & visual science 2026-08-16 19:24:04 | Source |
| Caregiver Communication and Preparedness During Transitions in Care:… Corabotase dose A · PMID 40387577 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Patients with severe and life-limiting illnesses transitioning out of the hospital often rely on family caregivers (FCG… | Journal of palliative medicine 2026-08-16 19:24:01 | Source |
| Healthcare use and out-of-pocket costs for rural family caregivers an… Corabotase dose A · PMID 38698643 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Rural family caregivers (FCGs) in the United States often experience high economic costs. This randomized controlled tr… | Journal of the American Geriatrics Society 2026-08-16 19:24:01 | Source |
| Transitional Palliative Care for Family Caregivers: Outcomes From a R… Corabotase dose A · PMID 39111586 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Patients receiving inpatient palliative care often face physical and psychological uncertainties during transitions out… | Journal of pain and symptom management 2026-08-16 19:24:01 | Source |
| Effect of Extracorporeal Shock Wave Therapy Combined With Kinesio Tap… I-SPY-RCT — Intervention for Sleep and Pain in Youth: A Randomized Controlled Trial · PMID 418… | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source To evaluate the main effects of extracorporeal shock wave therapy (ESWT) and Kinesio taping (KT) and their interaction… | Archives of physical medicine and rehabilitation 2026-08-16 19:23:58 | Source |
| Efficacy and safety of transcutaneous electrical nerve stimulation in… I-SPY-RCT — Intervention for Sleep and Pain in Youth: A Randomized Controlled Trial · PMID 424… | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Itching is a common and distressing clinical manifestation following burns, which severely impairs patient quality of l… | BMJ open 2026-08-16 19:23:58 | Source |
| Preoperative photobiomodulation reduces pain in molar surgery: A, dou… I-SPY-RCT — Intervention for Sleep and Pain in Youth: A Randomized Controlled Trial · PMID 423… | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Postoperative pain, swelling, and functional limitations are common after mandibular third molar surgery, affecting rec… | Journal of dentistry 2026-08-16 19:23:58 | Source |
| Percutaneous closure strategy in patients with patent foramen ovale a… Transcatheter Closure of Patent Foramen Ovale · PMID 42218325 | Migraine | À vérifier | Publication | PubMed | Voir la publication source In transcatheter closure of patent foramen ovale (PFO) associated with cryptogenic stroke (CS), a small coexisting atri… | Cardiovascular intervention and therapeutics 2026-08-16 19:23:57 | Source |
| Steering clear of the Chiari network pitfall in the transoesophageal… Transcatheter Closure of Patent Foramen Ovale · PMID 41618633 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Résumé non disponible dans la base locale. | European heart journal. Cardiovascular Imaging 2026-08-16 19:23:57 | Source |
| Transcatheter Closure of Patent Foramen Ovale - A Single Center Exper… Transcatheter Closure of Patent Foramen Ovale · PMID 42092276 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source A patent foramen ovale (PFO) is present in 20%-30% of the adult population. It is usually found in patients incidentall… | The Journal of surgical research 2026-08-16 19:23:57 | Source |
| A comparison of reduced-dose prasugrel and standard-dose clopidogrel… Prasugrel 5mg · PMID 27823681 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Elderly patients display higher on clopidogrel platelet reactivity as compared with younger patients. Treatment with pr… | American heart journal 2026-08-16 19:23:56 | Source |
| Residual platelet reactivity and outcomes with 5 mg prasugrel therapy… Prasugrel 5mg · PMID 25139323 | Migraine | À vérifier | Publication | PubMed | Voir la publication source In acute coronary syndrome (ACS) patients older than 75 years old, prasugrel 10 mg maintenance therapy has shown less c… | International journal of cardiology 2026-08-16 19:23:56 | Source |
| The influence of body size on the pharmacodynamic and pharmacokinetic… Prasugrel 5mg · PMID 25022828 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Patients treated with clopidogrel who have higher body size exhibit greater platelet reactivity than patients with lowe… | Thrombosis research 2026-08-16 19:23:56 | Source |
| Efficacy, Safety, and Tolerability of Atogepant in Migraine Patients… Atogepant · PMID 42154195 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Atogepant is an oral calcitonin gene-related peptide (CGRP) receptor antagonist approved for migraine prevention; howev… | Neurology and therapy 2026-08-16 19:23:53 | Source |
| Online interest in calcitonin gene-related peptide-therapies: An info… Ubrogepant · PMID 42265869 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source To evaluate changes in public interest in calcitonin gene-related peptide therapies associated with major product lifec… | Headache 2026-08-16 19:23:50 | Source |
| Population Pharmacokinetics and Exposure-Response Analyses for Ubroge… Ubrogepant · PMID 42212509 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source A population pharmacokinetic (popPK) model was developed for ubrogepant using data from 10 Phase 1, 1 Phase 2, and 2 Ph… | Journal of clinical pharmacology 2026-08-16 19:23:50 | Source |
| The pharmacology of gepants in migraine: A scoping review on mechanis… Ubrogepant · PMID 42265882 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Calcitonin gene-related peptide (CGRP) is a key mediator in migraine pathophysiology, and the development of gepants, n… | Headache 2026-08-16 19:23:50 | Source |
| Clinical associations during the year before Parkinson's disease diag… Propranolol · PMID 42261249 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Characterizing clinical associations before Parkinson's disease (PD) diagnosis may improve understanding of the diagnos… | Annals of medicine 2026-08-16 19:23:49 | Source |
| Oral propranolol treatment safety in infantile hemangiomas. Propranolol · PMID 42179355 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Infantile hemangiomas are common and can be treated with propranolol. Cardiovascular side effects are a potential risk… | The Journal of dermatological treatment 2026-08-16 19:23:49 | Source |
Exploration — prudence
Pistes exploratoires 5
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Bavisant BRAVEinMS — Bavisant | Migraine | Remyélinisation · Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Antagonisme du récepteur H3 de l’histamine Bavisant est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migra… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| Tol-MP Tol-MP — tolérance immunitaire spécifique de la myéline | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Microparticules biodégradables chargées en rapamycine et fonctionnalisées… Tol-MP est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migrain… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| SetPoint System SetPoint System — SetPoint Medical | Migraine | Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | re ApplicationsPublicationsCompanyCareersNewsGet startedGet startedNewsThe… SetPoint System est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation immunométabolique de la microglie 4-octyl itaconate et dérivés est étudié dans Sclérose latérale amyotrophique et documente plusieurs axes biologiques po… | Rapprochement Biomedical Watch · Sclérose latérale amy… | Détail |
| N-PPG N-PPG — modulation métabolique cérébrale | Migraine | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation métabolique et mitohormèse N-PPG est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être pertinents pour Migrai… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |