Vue transversale de la maladie
Migraine
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
Périmètre
Filtrer toute la vue
Chaque choix s’applique immédiatement aux quatre sections. Le filtre « type de SEP » n’apparaît que lorsque la sclérose en plaques est sélectionnée.
1236 résultats correspondants
· 45 visibles sur cette page
dans le périmètre Migraine
Niveau clinique
Études et traitements 570
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Fremanezumab NCT06173661 · Fremanezumab Treatment of Migraine in Women With Menstrual Migraine Ages 18-45 | Migraine | À vérifier | Phase 4 | COMPLETED | The goal of this observational study is to compare, in real-world clinical… À vérifier | ClinicalTrials.gov 2026-08-26 14:49:23 | Détail |
| IMAGINE — Music and Imagery for Veterans With Migraine Headache NCT06440876 · NCT06440876 | Migraine | À vérifier | Non applicable | COMPLETED | The purpose of this study is to determine feasibility and acceptability of… À vérifier | ClinicalTrials.gov 2026-08-26 14:49:23 | Détail |
| MIRAGE — Using Virtual Reality to Teach Mindfulness to People With Mi… NCT07599228 · NCT07599228 | Migraine | Ralentissement de la progression · Traitement symptomatique · Thérapie génique | Non applicable | NOT_YET_RECRUITING | The aim of this clinical trial is to learn if people with migraine can lea… À vérifier | ClinicalTrials.gov 2026-08-26 14:49:23 | Détail |
| Multi-Segmental Spinal Manual Therapy NCT07774286 · Multi-Segmental Spinal Manual Therapy in Women With Episodic Migraine | Migraine | Ralentissement de la progression · Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | The purpose of this study is to evaluate the clinical effects of multi-seg… À vérifier | ClinicalTrials.gov 2026-08-26 14:49:23 | Détail |
| Rimegepant NCT05198245 · Study of Pregnancy Outcomes in Women Exposed to Rimegepant During Pregnancy | Migraine | À vérifier | À vérifier | ACTIVE_NOT_RECRUITING | The purpose of this study is to evaluate safety and tolerability of BHV-30… À vérifier | ClinicalTrials.gov 2026-08-26 14:49:23 | Détail |
| Various Étude non communiquée | Migraine | À vérifier | À vérifier | Actif | The purpose of the study is to evaluate the risk of pregnancy and infant o… À vérifier | ClinicalTrials.gov 2026-08-21 | Détail |
| Magnesium Sulfate 4 G Étude non communiquée | Migraine | Ralentissement de la progression · Immunomodulation · Traitement symptomatique | Non applicable | Actif | Headache is one of the most common reasons for consultation in emergency d… À vérifier | ClinicalTrials.gov 2026-08-19 | Détail |
| Paracetamol 1 g Étude non communiquée | Migraine | Ralentissement de la progression · Immunomodulation · Traitement symptomatique | Non applicable | Actif | Headache is one of the most common reasons for consultation in emergency d… À vérifier | ClinicalTrials.gov 2026-08-19 | Détail |
| Melatonin NCT07721324 · SLE — Effect of Melatonin Administration on Systemic Lupus Erythematosus Patients | Lupus | Ralentissement de la progression · Traitement symptomatique · Thérapie génique | Phase 2/3 | NOT_YET_RECRUITING | This randomized controlled trial evaluated whether adding melatonin to pro… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:41 | Détail |
| Assessment of Inflammation in Primary Headaches NCT04891848 · NCT04891848 | Migraine | Immunomodulation · Thérapie génique | À vérifier | COMPLETED | Headache is the most common neurological complaint accounting for % 1 to %… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:24 | Détail |
| Eletriptan 20 mg NCT01978496 · Efficacy, Safety, and Tolerability of Oral Eletriptan for Treatment of Acute Mig… | Migraine | Traitement symptomatique | Phase 3 | COMPLETED | To confirm the efficacy of three dose levels of oral eletriptan relative t… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:24 | Détail |
| Eletriptan 40 mg NCT01986270 · Comparative Study of Oral Eletriptan (40mg and 80mg), Oral Sumatriptan (25mg and… | Migraine | À vérifier | Phase 3 | COMPLETED | The objective of this study was to compare the efficacy, toleration and sa… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:24 | Détail |
| Eletriptan 40 mg NCT01986088 · Eletriptan vs Sumatriptan: A Double-blind, Placebo-controlled, Multiple Migraine… | Migraine | À vérifier | Phase 3 | COMPLETED | The objective of this study was to compare the efficacy, toleration and sa… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:24 | Détail |
| Feraheme NCT02549898 · Investigation of Vascular Inflammation in Migraine Using Molecular Nano-imaging… | Migraine | Immunomodulation | Non applicable | COMPLETED | The investigators aim to investigate inflammation of cranial and meningeal… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:24 | Détail |
| Ibuprofen 400 mg NCT04533568 · Ibuprofen in Migraine Patients | Migraine | À vérifier | Phase 4 | COMPLETED | In this study, the investigators planned to compare the effectiveness of a… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:24 | Détail |
| Naltrexone and Acetaminophen NCT03061734 · ANODYNE-1 — Low-Dose Naltrexone and Acetaminophen Combination and Its Components… | Migraine | À vérifier | Phase 2 | COMPLETED | The study consists of a screening visit, out-patient treatment of a modera… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:24 | Détail |
| Naltrexone and Acetaminophen Combination NCT03185143 · Low-Dose Naltrexone and Acetaminophen Combination and Sumatriptan in the Acute T… | Migraine | À vérifier | Phase 2/3 | COMPLETED | This proof-of-concept study compares side-by-side low-dose naltrexone and… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:24 | Détail |
| Sham acupuncture combined with flunarizine hydrochloride NCT04766762 · A Randomized Controlled Trial of Acupuncture in Treating Migraine | Migraine | Traitement symptomatique · Thérapie génique | Non applicable | UNKNOWN | Migraine without aura is a common kind of nervous system diseases that can… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:24 | Détail |
| Sumatriptan 10 mg Nasal Spray NCT02856802 · An Efficacy and Safety Study of DFN-02 (Sumatriptan Nasal Spray 10 mg) | Migraine | À vérifier | Phase 2 | COMPLETED | A safety and efficacy study of DFN-02 (Sumatriptan Nasal Spray 10 mg), bei… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:24 | Détail |
| Ultrasound Guided Greater Occipital Nerve Block at C2 NCT03478735 · Ultrasound Greater Occipital Nerve Block at C2 Level Compared to Landmark-based… | Migraine | À vérifier | Non applicable | COMPLETED | This study will compare the analgesic benefit of a traditional landmark-gu… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:24 | Détail |
Découverte scientifique
Recherches et trouvailles 0
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune trouvaille ne correspond aux filtres. | |||||||
Bibliographie
Publications 661
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| From watershed to lagoon: Occurrence and ecological risk of paracetam… Paracetamol (acetaminophen) · PMID 42570042 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Pharmaceutical contamination in tropical coastal lagoons remains poorly characterized despite increasing anthropogenic… | Environmental science and pollution research internati… 2026-08-16 19:25:47 | Source |
| Metal nanocrystals and nanoclusters with paracetamol passivation and… Paracetamol (acetaminophen) · PMID 42483226 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Paracetamol (acetaminophen), being a well-used pharmaceutical drug, has several harmful health effects due to its overc… | Nanoscale advances 2026-08-16 19:25:47 | Source |
| Paracetamol-induced hepatic injury following intentional self-poisoni… Paracetamol (acetaminophen) · PMID 42573610 | Migraine | Ralentissement de la progression · Traitement symptomatique | Publication | PubMed | Voir la publication source Paracetamol (acetaminophen) overdose is a common cause of drug-induced hepatocellular injury and represents an importan… | Naunyn-Schmiedeberg's archives of pharmacology 2026-08-16 19:25:47 | Source |
| Knowledge About and the Use of Oral Nonsteroidal Anti-inflammatory Dr… NSAID (Nonsteroidal anti-inflammatory drugs) · PMID 38073919 | Migraine | Immunomodulation | Publication | PubMed | Voir la publication source The aims were to evaluate rheumatic disorder patients' knowledge of the side effects of nonsteroidal anti-inflammatory… | Cureus 2026-08-16 19:25:46 | Source |
| Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) Use Is Associated With… NSAID (Nonsteroidal anti-inflammatory drugs) · PMID 41293358 | Migraine | Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Background and objective Many patients across the United States suffer from migraines, which can be extremely painful a… | Cureus 2026-08-16 19:25:46 | Source |
| NSAID (nonsteroidal anti-inflammatory drugs) Induced Stevens Johnson… NSAID (Nonsteroidal anti-inflammatory drugs) · PMID 38469333 | Migraine | Immunomodulation | Publication | PubMed | Voir la publication source Stevens-Johnson Syndrome (SJS) is a severe and rare adverse drug reaction associated with significant morbidity and mor… | Toxicology reports 2026-08-16 19:25:46 | Source |
| Current Clinical Evidence on Nose-to-Brain Drug Delivery. triptans · PMID 42580438 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Intranasal delivery is increasingly recognised as a promising strategy for direct drug transport to the brain via the n… | Drug discovery today 2026-08-16 19:25:45 | Source |
| Efficacy analysis of combined nerve combing and decompression for occ… triptans · PMID 42003361 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source This study set occipital pain improvement as the primary endpoint, and overall headache relief, migraine index, medicat… | Annals of medicine 2026-08-16 19:25:45 | Source |
| A full-spectrum aqueous extract of black cardamom () improves focus/a… Caffeine (200 mg) · PMID 42027681 | Migraine | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Interest is increasing in natural, plant-based, food-grade nootropics that deliver sustained cognitive benefits without… | Frontiers in neuroscience 2026-08-16 19:25:42 | Source |
| Design and rationale of TROCADERO: A TRial Of Caffeine to Alleviate D… Caffeine (200 mg) · PMID 26385029 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Ticagrelor treatment has the side effect of increased incidence of dyspnea. Adenosine-induced dyspnea is augmented by t… | American heart journal 2026-08-16 19:25:42 | Source |
| A scheme to tackle the dilemma from hepatoma cells under doxorubicin-… Metoclopramide · PMID 42482449 | Migraine | À vérifier | Publication | PubMed | Voir la publication source The aim of this study was to investigate key target(s), mechanism(s) from hepatoma cells in harsh doxorubicin-resistant… | Artificial cells, nanomedicine, and biotechnology 2026-08-16 19:25:39 | Source |
| Comprehensive MRI analysis of olfactory bulb morphology and olfactory… Understanding the Pathophysiology of Migraine Pain · PMID 42162730 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source This study aimed to provide a comprehensive MRI-based assessment of olfactory bulb (OB) morphology and olfactory sulcus… | Neuroscience 2026-08-16 19:25:39 | Source |
| Pharmaceutical policy and off-label prescribing in pregnancy: A popul… Metoclopramide · PMID 42281148 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Nausea and vomiting in pregnancy is highly prevalent and can significantly impact pregnant women's quality of life. Des… | Acta obstetricia et gynecologica Scandinavica 2026-08-16 19:25:39 | Source |
| Receptor-Targeted Antiemetic Strategies in Cats: A Systematic Review… Metoclopramide · PMID 42599757 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Emesis is a common adverse effect in cats receiving alpha-2 adrenergic agonists and opioids and may compromise perioper… | Veterinary medicine and science 2026-08-16 19:25:39 | Source |
| The influence of chronotype on pain: a systematic review and meta-ana… Understanding the Pathophysiology of Migraine Pain · PMID 42153471 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Sleep and circadian rhythms play critical roles in pain regulation, yet the influence of chronotype remains underexplor… | Pain 2026-08-16 19:25:39 | Source |
| [Migraine in men: biological, psychosocial and clinical characteristi… Understanding the Pathophysiology of Migraine Pain · PMID 41995752 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Migraine affects 15% of the global population, with men being 2-3 times less frequently affected than women and are mar… | Schmerz (Berlin, Germany) 2026-08-16 19:25:39 | Source |
| Anti-inflammatory drugs disrupt granulosa cell homeostasis in vitro a… Ketoprofen · PMID 42308573 | Migraine | Immunomodulation | Publication | PubMed | Voir la publication source Granulosa cells (GCs) play a crucial role in maintaining follicular homeostasis and supporting the acquisition of oocyt… | Theriogenology 2026-08-16 19:25:38 | Source |
| Membrane-mediated mechanisms of NSAID-induced cardiotoxicity independ… Ketoprofen · PMID 42336296 | Migraine | Immunomodulation | Publication | PubMed | Voir la publication source Non-steroidal anti-inflammatory drugs (NSAIDs) are associated with cardiovascular adverse events that are not fully exp… | Toxicology and applied pharmacology 2026-08-16 19:25:38 | Source |
| Benzodiazepines use in Morocco: A nation wide consumption database st… Clorazepate Dipotassium · PMID 31759283 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Although information exists regarding the rate of benzodiazepines (BZDs) use in different countries, little information… | Asian journal of psychiatry 2026-08-16 19:25:35 | Source |
| Effect of Clomethiazole Vs. Clorazepate on Hepatic Fat and Serum Tran… Clorazepate Dipotassium · PMID 36562601 | Migraine | Neuroprotection | Publication | PubMed | Voir la publication source Alcohol-associated liver disease (ALD) is a global health problem caused, among other factors, by oxidative stress from… | Alcohol and alcoholism (Oxford, Oxfordshire) 2026-08-16 19:25:35 | Source |
Exploration — prudence
Pistes exploratoires 5
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Bavisant BRAVEinMS — Bavisant | Migraine | Remyélinisation · Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Antagonisme du récepteur H3 de l’histamine Bavisant est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migra… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| Tol-MP Tol-MP — tolérance immunitaire spécifique de la myéline | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Microparticules biodégradables chargées en rapamycine et fonctionnalisées… Tol-MP est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migrain… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| SetPoint System SetPoint System — SetPoint Medical | Migraine | Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | re ApplicationsPublicationsCompanyCareersNewsGet startedGet startedNewsThe… SetPoint System est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation immunométabolique de la microglie 4-octyl itaconate et dérivés est étudié dans Sclérose latérale amyotrophique et documente plusieurs axes biologiques po… | Rapprochement Biomedical Watch · Sclérose latérale amy… | Détail |
| N-PPG N-PPG — modulation métabolique cérébrale | Migraine | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation métabolique et mitohormèse N-PPG est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être pertinents pour Migrai… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |