Vue transversale de la maladie
Migraine
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
Périmètre
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1236 résultats correspondants
· 45 visibles sur cette page
dans le périmètre Migraine
Niveau clinique
Études et traitements 570
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Fremanezumab NCT06173661 · Fremanezumab Treatment of Migraine in Women With Menstrual Migraine Ages 18-45 | Migraine | À vérifier | Phase 4 | COMPLETED | The goal of this observational study is to compare, in real-world clinical… À vérifier | ClinicalTrials.gov 2026-08-26 14:49:23 | Détail |
| IMAGINE — Music and Imagery for Veterans With Migraine Headache NCT06440876 · NCT06440876 | Migraine | À vérifier | Non applicable | COMPLETED | The purpose of this study is to determine feasibility and acceptability of… À vérifier | ClinicalTrials.gov 2026-08-26 14:49:23 | Détail |
| MIRAGE — Using Virtual Reality to Teach Mindfulness to People With Mi… NCT07599228 · NCT07599228 | Migraine | Ralentissement de la progression · Traitement symptomatique · Thérapie génique | Non applicable | NOT_YET_RECRUITING | The aim of this clinical trial is to learn if people with migraine can lea… À vérifier | ClinicalTrials.gov 2026-08-26 14:49:23 | Détail |
| Multi-Segmental Spinal Manual Therapy NCT07774286 · Multi-Segmental Spinal Manual Therapy in Women With Episodic Migraine | Migraine | Ralentissement de la progression · Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | The purpose of this study is to evaluate the clinical effects of multi-seg… À vérifier | ClinicalTrials.gov 2026-08-26 14:49:23 | Détail |
| Rimegepant NCT05198245 · Study of Pregnancy Outcomes in Women Exposed to Rimegepant During Pregnancy | Migraine | À vérifier | À vérifier | ACTIVE_NOT_RECRUITING | The purpose of this study is to evaluate safety and tolerability of BHV-30… À vérifier | ClinicalTrials.gov 2026-08-26 14:49:23 | Détail |
| Various Étude non communiquée | Migraine | À vérifier | À vérifier | Actif | The purpose of the study is to evaluate the risk of pregnancy and infant o… À vérifier | ClinicalTrials.gov 2026-08-21 | Détail |
| Magnesium Sulfate 4 G Étude non communiquée | Migraine | Ralentissement de la progression · Immunomodulation · Traitement symptomatique | Non applicable | Actif | Headache is one of the most common reasons for consultation in emergency d… À vérifier | ClinicalTrials.gov 2026-08-19 | Détail |
| Paracetamol 1 g Étude non communiquée | Migraine | Ralentissement de la progression · Immunomodulation · Traitement symptomatique | Non applicable | Actif | Headache is one of the most common reasons for consultation in emergency d… À vérifier | ClinicalTrials.gov 2026-08-19 | Détail |
| Melatonin NCT07721324 · SLE — Effect of Melatonin Administration on Systemic Lupus Erythematosus Patients | Lupus | Ralentissement de la progression · Traitement symptomatique · Thérapie génique | Phase 2/3 | NOT_YET_RECRUITING | This randomized controlled trial evaluated whether adding melatonin to pro… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:41 | Détail |
| Assessment of Inflammation in Primary Headaches NCT04891848 · NCT04891848 | Migraine | Immunomodulation · Thérapie génique | À vérifier | COMPLETED | Headache is the most common neurological complaint accounting for % 1 to %… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:24 | Détail |
| Eletriptan 20 mg NCT01978496 · Efficacy, Safety, and Tolerability of Oral Eletriptan for Treatment of Acute Mig… | Migraine | Traitement symptomatique | Phase 3 | COMPLETED | To confirm the efficacy of three dose levels of oral eletriptan relative t… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:24 | Détail |
| Eletriptan 40 mg NCT01986270 · Comparative Study of Oral Eletriptan (40mg and 80mg), Oral Sumatriptan (25mg and… | Migraine | À vérifier | Phase 3 | COMPLETED | The objective of this study was to compare the efficacy, toleration and sa… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:24 | Détail |
| Eletriptan 40 mg NCT01986088 · Eletriptan vs Sumatriptan: A Double-blind, Placebo-controlled, Multiple Migraine… | Migraine | À vérifier | Phase 3 | COMPLETED | The objective of this study was to compare the efficacy, toleration and sa… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:24 | Détail |
| Feraheme NCT02549898 · Investigation of Vascular Inflammation in Migraine Using Molecular Nano-imaging… | Migraine | Immunomodulation | Non applicable | COMPLETED | The investigators aim to investigate inflammation of cranial and meningeal… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:24 | Détail |
| Ibuprofen 400 mg NCT04533568 · Ibuprofen in Migraine Patients | Migraine | À vérifier | Phase 4 | COMPLETED | In this study, the investigators planned to compare the effectiveness of a… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:24 | Détail |
| Naltrexone and Acetaminophen NCT03061734 · ANODYNE-1 — Low-Dose Naltrexone and Acetaminophen Combination and Its Components… | Migraine | À vérifier | Phase 2 | COMPLETED | The study consists of a screening visit, out-patient treatment of a modera… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:24 | Détail |
| Naltrexone and Acetaminophen Combination NCT03185143 · Low-Dose Naltrexone and Acetaminophen Combination and Sumatriptan in the Acute T… | Migraine | À vérifier | Phase 2/3 | COMPLETED | This proof-of-concept study compares side-by-side low-dose naltrexone and… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:24 | Détail |
| Sham acupuncture combined with flunarizine hydrochloride NCT04766762 · A Randomized Controlled Trial of Acupuncture in Treating Migraine | Migraine | Traitement symptomatique · Thérapie génique | Non applicable | UNKNOWN | Migraine without aura is a common kind of nervous system diseases that can… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:24 | Détail |
| Sumatriptan 10 mg Nasal Spray NCT02856802 · An Efficacy and Safety Study of DFN-02 (Sumatriptan Nasal Spray 10 mg) | Migraine | À vérifier | Phase 2 | COMPLETED | A safety and efficacy study of DFN-02 (Sumatriptan Nasal Spray 10 mg), bei… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:24 | Détail |
| Ultrasound Guided Greater Occipital Nerve Block at C2 NCT03478735 · Ultrasound Greater Occipital Nerve Block at C2 Level Compared to Landmark-based… | Migraine | À vérifier | Non applicable | COMPLETED | This study will compare the analgesic benefit of a traditional landmark-gu… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:24 | Détail |
Découverte scientifique
Recherches et trouvailles 0
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune trouvaille ne correspond aux filtres. | |||||||
Bibliographie
Publications 661
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Amylin Coexisting With Peptide YY (PYY) and Amylin/PYY Cells Correspo… Amylin · PMID 42559671 | Migraine | Immunomodulation | Publication | PubMed | Voir la publication source The distribution of amylin-like substances was investigated by immunohistochemistry in the pancreas of the Japanese eel… | Anatomia, histologia, embryologia 2026-08-08 00:58:52 | Source |
| Acute effects of "exercise snacks" on postprandial glucose and insuli… Endothelin-1 · PMID 42558375 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source Exercise snacks-short, frequent bouts of physical activity that interrupt prolonged sitting-improve postprandial glucos… | Frontiers in endocrinology 2026-08-08 00:58:51 | Source |
| Hypoxemia with atelectasis during clazosentan therapy after subarachn… Endothelin-1 · PMID 42558750 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Clazosentan, a selective endothelin-A (ET-A) receptor antagonist, is used to prevent cerebral vasospasm after aneurysma… | Nagoya journal of medical science 2026-08-08 00:58:51 | Source |
| Emerging Neurovascular Interventions for the Prevention of Cerebral V… Cilostazol · PMID 42540693 | Migraine | Neuroprotection · Immunomodulation | Publication | PubMed | Voir la publication source Aneurysmal subarachnoid hemorrhage remains a major cause of neurological morbidity and mortality, with delayed cerebral… | Cureus 2026-08-08 00:58:50 | Source |
| Isosorbide Mononitrate/Cilostazol for Lacunar Cerebral Small Vessel D… Cilostazol · PMID 42535538 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Lacunar stroke can cause cognitive decline and dependency. The LACI-2 (Lacunar Intervention Trial-2) trial showed that… | Journal of the American Heart Association 2026-08-08 00:58:50 | Source |
| Twelve-months prospective real-world assessment of effectiveness and… Eptinezumab 100 mg or Eptinezumab 300 mg administered intravenously in 100 mL saline solution… | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Randomized clinical trials have demonstrated the efficacy and safety of eptinezumab. The aim of this study was to evalu… | The journal of headache and pain 2026-08-08 00:58:47 | Source |
| Targeting G-coupled GPCRs to inhibit nociceptors: Insights from the s… Triptan · PMID 42532046 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Pain perception is initiated upon activation of nociceptors of the dorsal root ganglia (DRG) and trigeminal ganglia. We… | Cell reports. Medicine 2026-08-08 00:58:45 | Source |
| Gastrointestinal Ascariasis: Unusual Presentation in 2 Cases. Non-steroidal anti-inflammatory drug (NSAID) · PMID 42540124 | Migraine | Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Ascariasis is a helminthic infection caused by the nematode and remains the most prevalent helminth infection worldwide… | Nigerian medical journal : journal of the Nigeria Medi… 2026-08-08 00:58:44 | Source |
| Impact of semaglutide introduction on the use of triptans: an interru… Triptan · PMID 42557547 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Emerging evidence suggests that glucagon-like peptide-1 receptor agonist (GLP-1RA) may be associated with reduced migra… | The journal of headache and pain 2026-08-08 00:58:44 | Source |
| In Vitro Evaluation of Lornoxicam Liquitablets: Permeability, Anti-In… Non-steroidal anti-inflammatory drug (NSAID) · PMID 42546887 | Migraine | Immunomodulation · Thérapie génique | Publication | PubMed | Voir la publication source Lornoxicam (LXM) is a potent non-steroidal anti-inflammatory drug (NSAID), characterised by low aqueous solubility, whi… | European journal of pharmaceutical sciences : official… 2026-08-08 00:58:44 | Source |
| Botulinum toxin in peripheral facial paralysis: systematic review and… Onabotulinum toxin A · PMID 42517166 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Peripheral facial paralysis (PFP) causes both static and dynamic facial dysfunctions, leading to synkinesis, hypertonia… | European journal of physical and rehabilitation medici… 2026-08-08 00:58:43 | Source |
| Repeated botulinum toxin injections for neurogenic thoracic outlet sy… Onabotulinum toxin A · PMID 42550976 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Neurogenic thoracic outlet syndrome (nTOS) is a condition caused by compression of the brachial plexus in the thoracic… | Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = T… 2026-08-08 00:58:43 | Source |
| Projected budget impact of pharmacotherapy scenarios for obesity and… topiramate · PMID 42565180 | Migraine | À vérifier | Publication | PubMed | Voir la publication source The increasing prevalence of obesity is generating demand for chronic pharmacologic treatment, but Latin American evide… | Obesity pillars 2026-08-08 00:58:42 | Source |
| Weight mitigation and tolerability of adjunctive topiramate in acute… topiramate · PMID 42558898 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Psychotropic medications are often associated with significant and rapid weight gain in pediatric populations, especial… | Frontiers in psychiatry 2026-08-08 00:58:42 | Source |
| Feasibility of Emotional Awareness and Expression Therapy Adapted for… Exploring Clinical Trial Experiences of Patients With Migraine · PMID 41742651 | Migraine | Ralentissement de la progression | Publication | PubMed | Voir la publication source Chronic headache, including migraine, is often associated with psychiatric conditions and adverse childhood experiences… | The Canadian journal of neurological sciences. Le jour… 2026-08-08 00:58:38 | Source |
| Physical Therapy Targeting Autonomic and Dura Mater Function: SPINEPA… Exploring Clinical Trial Experiences of Patients With Migraine · PMID 41324433 | Migraine | Ralentissement de la progression · Traitement symptomatique | Publication | PubMed | Voir la publication source Persistent post-traumatic headache (PPTH) or concussion is a significant United States military problem, and pharmacolo… | Physical therapy 2026-08-08 00:58:38 | Source |
| Efficacy and safety of gepants in migraine management: a narrative re… Rimegepant 75 MG · PMID 42548099 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Gepants, oral antagonists of the calcitonin gene-related peptide (CGRP) receptor, represent a new therapeutic class in… | Journal of oral & facial pain and headache 2026-08-08 00:58:35 | Source |
| Diagnostic value of shear wave elastography in assessing the effectiv… Botulinum toxin type A · PMID 42566101 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source Complex W3 ventral hernias with loss of domain (LOD) pose challenges in abdominal wall reconstruction due to pathologic… | Hernia : the journal of hernias and abdominal wall sur… 2026-08-08 00:58:34 | Source |
| [Treatment persistence and adherence with botulinum toxin type A and… Botulinum toxin type A · PMID 42565401 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source To compare the treatment persistence and adherence with botulinum toxin type A (Relatox; BTA) and monoclonal antibodies… | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 2026-08-08 00:58:34 | Source |
| Multi-organ AI endophenotypes chart the heterogeneity of brain, eye a… Digoxin · PMID 42559122 | Migraine | Ralentissement de la progression · Thérapie génique | Publication | PubMed | Voir la publication source Disease heterogeneity and commonality pose significant challenges to precision medicine, as traditional approaches freq… | Nature. Mental health 2026-08-08 00:57:54 | Source |
Exploration — prudence
Pistes exploratoires 5
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Bavisant BRAVEinMS — Bavisant | Migraine | Remyélinisation · Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Antagonisme du récepteur H3 de l’histamine Bavisant est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migra… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| Tol-MP Tol-MP — tolérance immunitaire spécifique de la myéline | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Microparticules biodégradables chargées en rapamycine et fonctionnalisées… Tol-MP est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migrain… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| SetPoint System SetPoint System — SetPoint Medical | Migraine | Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | re ApplicationsPublicationsCompanyCareersNewsGet startedGet startedNewsThe… SetPoint System est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation immunométabolique de la microglie 4-octyl itaconate et dérivés est étudié dans Sclérose latérale amyotrophique et documente plusieurs axes biologiques po… | Rapprochement Biomedical Watch · Sclérose latérale amy… | Détail |
| N-PPG N-PPG — modulation métabolique cérébrale | Migraine | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation métabolique et mitohormèse N-PPG est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être pertinents pour Migrai… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |