Vue transversale de la maladie
Migraine
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
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1236 résultats correspondants
· 45 visibles sur cette page
dans le périmètre Migraine
Niveau clinique
Études et traitements 570
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Fremanezumab NCT06173661 · Fremanezumab Treatment of Migraine in Women With Menstrual Migraine Ages 18-45 | Migraine | À vérifier | Phase 4 | COMPLETED | The goal of this observational study is to compare, in real-world clinical… À vérifier | ClinicalTrials.gov 2026-08-26 14:49:23 | Détail |
| IMAGINE — Music and Imagery for Veterans With Migraine Headache NCT06440876 · NCT06440876 | Migraine | À vérifier | Non applicable | COMPLETED | The purpose of this study is to determine feasibility and acceptability of… À vérifier | ClinicalTrials.gov 2026-08-26 14:49:23 | Détail |
| MIRAGE — Using Virtual Reality to Teach Mindfulness to People With Mi… NCT07599228 · NCT07599228 | Migraine | Ralentissement de la progression · Traitement symptomatique · Thérapie génique | Non applicable | NOT_YET_RECRUITING | The aim of this clinical trial is to learn if people with migraine can lea… À vérifier | ClinicalTrials.gov 2026-08-26 14:49:23 | Détail |
| Multi-Segmental Spinal Manual Therapy NCT07774286 · Multi-Segmental Spinal Manual Therapy in Women With Episodic Migraine | Migraine | Ralentissement de la progression · Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | The purpose of this study is to evaluate the clinical effects of multi-seg… À vérifier | ClinicalTrials.gov 2026-08-26 14:49:23 | Détail |
| Rimegepant NCT05198245 · Study of Pregnancy Outcomes in Women Exposed to Rimegepant During Pregnancy | Migraine | À vérifier | À vérifier | ACTIVE_NOT_RECRUITING | The purpose of this study is to evaluate safety and tolerability of BHV-30… À vérifier | ClinicalTrials.gov 2026-08-26 14:49:23 | Détail |
| Various Étude non communiquée | Migraine | À vérifier | À vérifier | Actif | The purpose of the study is to evaluate the risk of pregnancy and infant o… À vérifier | ClinicalTrials.gov 2026-08-21 | Détail |
| Magnesium Sulfate 4 G Étude non communiquée | Migraine | Ralentissement de la progression · Immunomodulation · Traitement symptomatique | Non applicable | Actif | Headache is one of the most common reasons for consultation in emergency d… À vérifier | ClinicalTrials.gov 2026-08-19 | Détail |
| Paracetamol 1 g Étude non communiquée | Migraine | Ralentissement de la progression · Immunomodulation · Traitement symptomatique | Non applicable | Actif | Headache is one of the most common reasons for consultation in emergency d… À vérifier | ClinicalTrials.gov 2026-08-19 | Détail |
| Melatonin NCT07721324 · SLE — Effect of Melatonin Administration on Systemic Lupus Erythematosus Patients | Lupus | Ralentissement de la progression · Traitement symptomatique · Thérapie génique | Phase 2/3 | NOT_YET_RECRUITING | This randomized controlled trial evaluated whether adding melatonin to pro… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:41 | Détail |
| Assessment of Inflammation in Primary Headaches NCT04891848 · NCT04891848 | Migraine | Immunomodulation · Thérapie génique | À vérifier | COMPLETED | Headache is the most common neurological complaint accounting for % 1 to %… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:24 | Détail |
| Eletriptan 20 mg NCT01978496 · Efficacy, Safety, and Tolerability of Oral Eletriptan for Treatment of Acute Mig… | Migraine | Traitement symptomatique | Phase 3 | COMPLETED | To confirm the efficacy of three dose levels of oral eletriptan relative t… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:24 | Détail |
| Eletriptan 40 mg NCT01986270 · Comparative Study of Oral Eletriptan (40mg and 80mg), Oral Sumatriptan (25mg and… | Migraine | À vérifier | Phase 3 | COMPLETED | The objective of this study was to compare the efficacy, toleration and sa… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:24 | Détail |
| Eletriptan 40 mg NCT01986088 · Eletriptan vs Sumatriptan: A Double-blind, Placebo-controlled, Multiple Migraine… | Migraine | À vérifier | Phase 3 | COMPLETED | The objective of this study was to compare the efficacy, toleration and sa… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:24 | Détail |
| Feraheme NCT02549898 · Investigation of Vascular Inflammation in Migraine Using Molecular Nano-imaging… | Migraine | Immunomodulation | Non applicable | COMPLETED | The investigators aim to investigate inflammation of cranial and meningeal… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:24 | Détail |
| Ibuprofen 400 mg NCT04533568 · Ibuprofen in Migraine Patients | Migraine | À vérifier | Phase 4 | COMPLETED | In this study, the investigators planned to compare the effectiveness of a… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:24 | Détail |
| Naltrexone and Acetaminophen NCT03061734 · ANODYNE-1 — Low-Dose Naltrexone and Acetaminophen Combination and Its Components… | Migraine | À vérifier | Phase 2 | COMPLETED | The study consists of a screening visit, out-patient treatment of a modera… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:24 | Détail |
| Naltrexone and Acetaminophen Combination NCT03185143 · Low-Dose Naltrexone and Acetaminophen Combination and Sumatriptan in the Acute T… | Migraine | À vérifier | Phase 2/3 | COMPLETED | This proof-of-concept study compares side-by-side low-dose naltrexone and… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:24 | Détail |
| Sham acupuncture combined with flunarizine hydrochloride NCT04766762 · A Randomized Controlled Trial of Acupuncture in Treating Migraine | Migraine | Traitement symptomatique · Thérapie génique | Non applicable | UNKNOWN | Migraine without aura is a common kind of nervous system diseases that can… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:24 | Détail |
| Sumatriptan 10 mg Nasal Spray NCT02856802 · An Efficacy and Safety Study of DFN-02 (Sumatriptan Nasal Spray 10 mg) | Migraine | À vérifier | Phase 2 | COMPLETED | A safety and efficacy study of DFN-02 (Sumatriptan Nasal Spray 10 mg), bei… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:24 | Détail |
| Ultrasound Guided Greater Occipital Nerve Block at C2 NCT03478735 · Ultrasound Greater Occipital Nerve Block at C2 Level Compared to Landmark-based… | Migraine | À vérifier | Non applicable | COMPLETED | This study will compare the analgesic benefit of a traditional landmark-gu… À vérifier | ClinicalTrials.gov 2026-08-16 21:21:24 | Détail |
Découverte scientifique
Recherches et trouvailles 0
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune trouvaille ne correspond aux filtres. | |||||||
Bibliographie
Publications 661
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Case Report: Anodal DLPFC-tDCS for refractory post-traumatic cognitiv… Galcanezumab · PMID 42602261 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Cognitive fatigue is among the most common and disabling long-term sequelae of mild traumatic brain injury (mTBI), with… | Frontiers in human neuroscience 2026-08-16 19:23:06 | Source |
| High Cervical 10 kHz Spinal Cord Stimulation After Occipital Nerve St… Occipital Nerve Stimulation · PMID 42573543 | Migraine | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source In this retrospective study, we evaluated high-frequency spinal cord stimulation (SCS) as an alternative neuromodulatio… | Neuromodulation : journal of the International Neuromo… 2026-08-16 19:23:03 | Source |
| Global prevalence and disability burden of brain disorders: Impact of… BE WELL With Migraine: Brain Education and WELLness With Migraine · PMID 42269957 | Migraine | Ralentissement de la progression | Publication | PubMed | Voir la publication source Brain disorders-encompassing neurological, mental, and substance use disorders-account for 10 of the top 25 causes of d… | Neuroscience and biobehavioral reviews 2026-08-16 19:22:56 | Source |
| NXN-188, a selective nNOS inhibitor and a 5-HT1B/1D receptor agonist,… NXN-188 · PMID 23155193 | Migraine | À vérifier | Publication | PubMed | Voir la publication source NXN-188 is a combined neuronal nitric oxide synthase (nNOS) inhibitor and 5-hydroxytryptamine 1B/1D (5-HT1B/1D) recepto… | Cephalalgia : an international journal of headache 2026-08-16 19:22:51 | Source |
| Vestibular cortex-related effective connectivity signatures: characte… Vestibular System in Migrainous Vertigo Patients · PMID 42337425 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Neuroimaging studies of vestibular migraine (VM) have revealed abnormal functional connectivity in the central vestibul… | The journal of headache and pain 2026-08-16 19:22:46 | Source |
| Cultured Epidermal Autograft Formation With Reduced Platelet-Rich Pla… blood withdrawal · PMID 42424623 | Migraine | Immunomodulation | Publication | PubMed | Voir la publication source Cultured epidermal autografts (CEA) reportedly have better cosmesis than traditional autografts and are especially usef… | The Journal of craniofacial surgery 2026-08-16 19:22:45 | Source |
| Impact of acute high thoracic spinal cord injury on in vivo vascular… blood withdrawal · PMID 42219075 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Cardiovascular dysfunction is a major cause of morbidity and mortality following high-thoracic spinal cord injury (SCI)… | Experimental neurology 2026-08-16 19:22:45 | Source |
| Practice-Based Consensus Amongst Indian Neurologists: Adopting Remote… Nerivio ® · PMID 41697517 | Migraine | Ralentissement de la progression | Publication | PubMed | Voir la publication source Migraine is a major cause of disability in India, disproportionately affecting women and adolescents. Although traditio… | Advances in therapy 2026-08-16 19:22:41 | Source |
| Ultrasound-guided 5-in-1 trigger point injection for treating tension… Greater Occipital Nerve Block with 0.9% saline · PMID 35945722 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Tension-type headache (TTH) is the most common type of primary headache, and trigger point injection (TPI) is frequentl… | Medicine 2026-08-16 19:22:37 | Source |
| The consequences of the new European reclassification of non-invasive… tDCS device from neuroConn · PMID 38679530 | Migraine | À vérifier | Publication | PubMed | Voir la publication source A significant amount of European basic and clinical neuroscience research includes the use of transcranial magnetic sti… | Clinical neurophysiology : official journal of the Int… 2026-08-16 19:22:35 | Source |
| Prescription of cardiovascular drugs in the French ODIN cohort of hea… Part A: TRV250-20mg/ml · PMID 24388162 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Chronic heart failure (CHF) is a frequent severe disease. Disease-management programmes, which contain a therapeutic pa… | Archives of cardiovascular diseases 2026-08-16 19:22:24 | Source |
| Socioeconomic factors and mortality in diastolic heart failure. Part A: TRV250-20mg/ml · PMID 24467732 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Mortality in patients with heart failure with preserved ejection fraction (HFPEF) has remained stable over recent decad… | European journal of clinical investigation 2026-08-16 19:22:24 | Source |
| [Neurostimulation of the supraorbital nerve with the Cefaly device -… Cefaly device · PMID 31089108 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source Treatment of migraine mainly includes pharmacological approaches aimed at breaking migraine attacks and preventive trea… | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 2026-08-16 19:22:19 | Source |
| Management of refractory chronic migraine using ultrasound-guided pul… Efficacy of Greater Occipital Nerve Radiofrequency for Refractory Migraine Treatment · PMID 30… | Migraine | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Although various oral medications and procedures are applied for managing migraine, their efficacy remains limited. To… | Medicine 2026-08-16 19:22:18 | Source |
| Comparative efficacy, quality of life, safety, and tolerability of at… Rimegepant/BHV3000 · PMID 38410850 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Comparative evaluations of preventive migraine treatments can help inform clinical decision making for managing migrain… | Cephalalgia : an international journal of headache 2026-08-16 19:22:17 | Source |
| Cost per treatment responder analysis of atogepant compared to rimege… Rimegepant/BHV3000 · PMID 39248007 | Migraine | À vérifier | Publication | PubMed | Voir la publication source To estimate the number needed to treat and cost per additional responder for atogepant and rimegepant versus placebo fo… | Headache 2026-08-16 19:22:17 | Source |
| Pharmacological interventions for antipsychotic-induced weight gain i… Topiramate 100 mg · PMID 38878592 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Antipsychotic-induced weight gain (AIWG) is a significant but frequently neglected adverse effect of first- and second-… | General hospital psychiatry 2026-08-16 19:22:16 | Source |
| Propranolol Versus Metoprolol for Treatment of Electrical Storm in Pa… Propranolol 160 mg · PMID 29699616 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Electrical storm (ES), characterized by unrelenting recurrences of ventricular arrhythmias, is observed in approximatel… | Journal of the American College of Cardiology 2026-08-16 19:22:16 | Source |
| Tolerability, safety, and efficacy of atogepant versus topiramate in… Atogepant 60 mg · PMID 42492556 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Oral calcitonin gene-related peptide (CGRP) receptor antagonists such as atogepant have been approved for preventive tr… | The Lancet. Neurology 2026-08-16 19:22:14 | Source |
| Encephalopathy following subcutaneous administration of Brixadi® exte… Fentanyl · PMID 42571226 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Long-acting injectable buprenorphine is one option for the management of opioid use disorder. The United States Food an… | Toxicology reports 2026-08-16 19:22:13 | Source |
Exploration — prudence
Pistes exploratoires 5
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Bavisant BRAVEinMS — Bavisant | Migraine | Remyélinisation · Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Antagonisme du récepteur H3 de l’histamine Bavisant est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migra… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| Tol-MP Tol-MP — tolérance immunitaire spécifique de la myéline | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Microparticules biodégradables chargées en rapamycine et fonctionnalisées… Tol-MP est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migrain… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| SetPoint System SetPoint System — SetPoint Medical | Migraine | Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | re ApplicationsPublicationsCompanyCareersNewsGet startedGet startedNewsThe… SetPoint System est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation immunométabolique de la microglie 4-octyl itaconate et dérivés est étudié dans Sclérose latérale amyotrophique et documente plusieurs axes biologiques po… | Rapprochement Biomedical Watch · Sclérose latérale amy… | Détail |
| N-PPG N-PPG — modulation métabolique cérébrale | Migraine | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation métabolique et mitohormèse N-PPG est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être pertinents pour Migrai… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |