Vue transversale de la maladie
Migraine
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
Périmètre
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1236 résultats correspondants
· 45 visibles sur cette page
dans le périmètre Migraine
Niveau clinique
Études et traitements 570
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Wrist-watch sensor device Étude non communiquée | Migraine | À vérifier | Non applicable | Actif | The purpose of this project is to provide a new framework for diagnosing a… À vérifier | ClinicalTrials.gov 2026-09-02 | Détail |
| Adrenomedullin NCT07451769 · Selective Activation of the Adrenomedullin Receptors in Migraine | Migraine | À vérifier | Non applicable | RECRUITING | Adrenomedullin is a neuropeptide implicated in the pathogenesis of migrain… À vérifier | ClinicalTrials.gov 2026-09-01 09:22:10 | Détail |
| BR005-036C NCT07792681 · Efficacy and Safety of BR005-036C Tablets for the Acute Treatment of Migraine in… | Migraine | À vérifier | Phase 2/3 | NOT_YET_RECRUITING | The purpose of this study is to compare the efficacy and safety of BR005-0… À vérifier | ClinicalTrials.gov 2026-09-01 09:22:10 | Détail |
| Brave-Mind — Behavioral Resources and Awareness for Veterans With Epi… NCT07792291 · NCT07792291 | Migraine | À vérifier | Non applicable | NOT_YET_RECRUITING | The current study will evaluate effectiveness of cognitive behavioral ther… À vérifier | ClinicalTrials.gov 2026-09-01 09:22:10 | Détail |
| Brief Interventions in Chronic Migraine NCT05979337 · NCT05979337 | Migraine | Ralentissement de la progression · Traitement symptomatique | Non applicable | COMPLETED | People with chronic migraine headaches face many challenges, including hig… À vérifier | ClinicalTrials.gov 2026-09-01 09:22:10 | Détail |
| Elismetrep (K-304) 2 mg NCT06848075 · A Phase IIb, Randomized, Double-Blind, Placebo-Controlled Study of Elismetrep (K… | Migraine | À vérifier | Phase 2 | COMPLETED | This is a double-blind, randomized, multicenter, outpatient evaluation of… À vérifier | ClinicalTrials.gov 2026-09-01 09:22:10 | Détail |
| Static magnetic helmet NCT07584382 · The Effect of Static Magnetic Fields on Neuroinflammation in Migraine | Migraine | Immunomodulation · Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | We are conducting this research in individuals with migraines to find out… À vérifier | ClinicalTrials.gov 2026-09-01 09:22:10 | Détail |
| The Effects of Physiotherapy in Migraine NCT07657377 · NCT07657377 | Migraine | Traitement symptomatique | Non applicable | RECRUITING | The aim of this study is to investigate the effects of a physiotherapy pro… À vérifier | ClinicalTrials.gov 2026-09-01 09:22:10 | Détail |
| Cilostazol NCT03109288 · Targeting Residual Activity By Precision, Biomarker-Guided Combination Therapies… | Sclérose en plaques | À vérifier | Phase 1/2 | RECRUITING | In a double blind placebo-controlled cross-over study the effect of cilost… À vérifier | ClinicalTrials.gov 2026-09-01 09:21:54 | Détail |
| EVO756, Dose 2 Étude non communiquée | Migraine | À vérifier | Phase 2 | Actif | This study will evaluate the efficacy and safety of EVO756 against placebo… À vérifier | ClinicalTrials.gov 2026-09-01 | Détail |
| Stellate gangion blockade %1 5 mL Étude non communiquée | Migraine | Ralentissement de la progression · Traitement symptomatique | Non applicable | Terminé | Stellate Ganglion Block (SGB) is an interventional anesthetic technique us… À vérifier | ClinicalTrials.gov 2026-09-01 | Détail |
| Dexmedetomidine NCT07769255 · Effect of Nebulized Dexmedetomidine on Central Sensitization and Chronification… | Migraine | Traitement symptomatique · Thérapie génique | Non applicable | RECRUITING | Migraine is a debilitating neurological disorder characterized by recurren… À vérifier | ClinicalTrials.gov 2026-08-26 14:49:25 | Détail |
| Active Remote Electrical Neuromodulation NCT07772427 · Neuromodulation During the Prodrome to Prevent Disabling Migraine Attacks in You… | Migraine | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | Background \& Rationale: One in ten Canadian youth have migraine, a disabl… À vérifier | ClinicalTrials.gov 2026-08-26 14:49:24 | Détail |
| HEAD-FLEX — Personalised Process-based Psychological Interventions fo… NCT07418723 · NCT07418723 | Migraine | Ralentissement de la progression | Non applicable | COMPLETED | This project was an empirical single-case experimental design (SCED) study… À vérifier | ClinicalTrials.gov 2026-08-26 14:49:24 | Détail |
| Magnesium Sulfate 2 grams NCT07779486 · MAGHEAD — High- vs Standard-Dose Intravenous Magnesium for Acute Headache | Migraine | Ralentissement de la progression · Immunomodulation · Traitement symptomatique | Non applicable | RECRUITING | Headache is one of the most common reasons for consultation in emergency d… À vérifier | ClinicalTrials.gov 2026-08-26 14:49:24 | Détail |
| Mechanism-Based Cervical Rehabilitation for Chronic Migraine NCT07762690 · NCT07762690 | Migraine | À vérifier | Non applicable | NOT_YET_RECRUITING | To investigate the effectiveness of mechanism-based cervical sensorimotor… À vérifier | ClinicalTrials.gov 2026-08-26 14:49:24 | Détail |
| Rimegepant NCT07609914 · A Study to Learn About the Safety of Taking an Additional Dose of the Medicine R… | Migraine | À vérifier | Phase 4 | RECRUITING | The purpose of this study is to evaluate safety and tolerability of BHV-30… À vérifier | ClinicalTrials.gov 2026-08-26 14:49:24 | Détail |
| Rimegepant 75 mg ODT NCT07685769 · A Study to Find Out if the Medicine Called Rimegepant is Safe for Adults in India | Migraine | À vérifier | Phase 4 | RECRUITING | This is a multicenter, single-arm, open-label Phase 4 study evaluating the… À vérifier | ClinicalTrials.gov 2026-08-26 14:49:24 | Détail |
| Ultrasound-guided pulsed radiofrequency (PRF) NCT07780136 · Comparison of the Effectiveness of Greater Occipital Nerve and Supratrochlear Ne… | Migraine | Ralentissement de la progression · Traitement symptomatique · Thérapie génique | Phase 4 | NOT_YET_RECRUITING | Migraine is a common chronic neurovascular disorder ranked among the leadi… À vérifier | ClinicalTrials.gov 2026-08-26 14:49:24 | Détail |
| Cryoneurolysis NCT06554886 · A Study Investigating Peripheral Cryoneurolysis in Adults With Chronic Migraine | Migraine | Traitement symptomatique | Non applicable | ACTIVE_NOT_RECRUITING | The trial is a research study that tests a freezing technique called cryon… À vérifier | ClinicalTrials.gov 2026-08-26 14:49:23 | Détail |
Découverte scientifique
Recherches et trouvailles 0
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune trouvaille ne correspond aux filtres. | |||||||
Bibliographie
Publications 661
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Efficacy of Greater Occipital Nerve Blockade in Craniofacial Neuralgi… Greater Occipital Nerve Block with dexamethasone and lidocaine · PMID 40725724 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source : Greater occipital nerve blockade (GONB) is a minimally invasive intervention used to treat primary headaches. However… | Journal of clinical medicine 2026-08-08 00:59:43 | Source |
| Greater occipital nerve blockade for the preventive treatment of chro… Greater Occipital Nerve Block with 0.9% saline · PMID 36739512 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Greater occipital nerve blockade for the prevention of chronic migraine has a limited evidence base. A robust randomize… | Cephalalgia : an international journal of headache 2026-08-08 00:59:43 | Source |
| Three men in a boat: The comparison of the combination therapy of bot… Greater Occipital Nerve Block with 0.9% saline · PMID 36731164 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source This study compared the impact of the combination therapy of onabotulinum toxin A and greater occipital nerve block (Go… | Clinical neurology and neurosurgery 2026-08-08 00:59:43 | Source |
| High dosage accelerated intermittent theta burst stimulation without… tDCS device from neuroConn · PMID 40705070 | Migraine | À vérifier | Publication | PubMed | Voir la publication source High dosage accelerated intermittent theta-burst stimulation (aiTBS) protocols (10 sessions per day for 5 days) combine… | European archives of psychiatry and clinical neuroscie… 2026-08-08 00:59:42 | Source |
| Report Approval for Transcranial Electrical Stimulation (RATES): expe… tDCS device from neuroConn · PMID 41044265 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Transcranial electrical stimulation (tES) has gained substantial momentum as a research and therapeutic tool; however,… | Nature protocols 2026-08-08 00:59:42 | Source |
| Artificial intelligence-based decision support in simulated free flap… Migraine surgery · PMID 42326044 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Free flap compromise after head and neck reconstruction requires rapid recognition and structured escalation. Large lan… | JPRAS open 2026-08-08 00:59:41 | Source |
| Corrugator Supercilii Muscle and Its Relationship with Neurovascular… Migraine surgery · PMID 42192010 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source The corrugator supercilii muscle (CSM) is a critical anatomical target for botulinum toxin injections and surgical inte… | Aesthetic plastic surgery 2026-08-08 00:59:41 | Source |
| Efficacy and tolerability of combination treatment of topiramate and… PROMPT-IN — A Study of Prophylaxis for Migraine Patients With Topiramate in India · PMID 35259… | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source To compare the efficacy and tolerability of combination treatment of topiramate and greater occipital nerve block to to… | Cephalalgia : an international journal of headache 2026-08-08 00:59:40 | Source |
| Vitamin D Deficiency and Supplementation in Migraine: A Scoping Revie… PROMPT-IN — A Study of Prophylaxis for Migraine Patients With Topiramate in India · PMID 41233… | Migraine | Ralentissement de la progression · Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Migraine is a debilitating neurological disorder affecting 10%-20% of the global population, with significant socioecon… | Annals of Indian Academy of Neurology 2026-08-08 00:59:40 | Source |
| A Phase I, Randomized, Single‑Blind, Placebo‑Controlled, Single Ascen… Part B: TRV250 Dose 1 · PMID 32676977 | Migraine | À vérifier | Publication | PubMed | Voir la publication source The delta opioid receptor (DOR) has been identified as a therapeutic target for migraine, with DOR agonists exhibiting… | CNS drugs 2026-08-08 00:59:37 | Source |
| Investigation of a foodborne outbreak of Shigella sonnei in Ireland a… Part A: TRV250-20mg/ml · PMID 32120067 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source To describe a cross-border foodborne outbreak of Shigella sonnei that occurred in Ireland and Northern Ireland (NI) in… | Public health 2026-08-08 00:59:36 | Source |
| Outbreak of hepatitis A infection associated with the consumption of… Part A: TRV250-20mg/ml · PMID 25375902 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source In May 2013, a European alert was issued regarding a hepatitis A virus (HAV) outbreak in Italy. In June 2013, HAV subge… | Euro surveillance : bulletin Europeen sur les maladies… 2026-08-08 00:59:36 | Source |
| Alterations of Resting-State Locus Coeruleus Functional Connectivity… Cefaly device · PMID 35619611 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Transdermal trigeminal electrical neuromodulation (TTEN) is a novel treatment modality that is known for noradrenergic… | Frontiers in psychiatry 2026-08-08 00:59:33 | Source |
| Efficacy of ultrasound-guided greater occipital nerve pulsed radiofre… Efficacy of Greater Occipital Nerve Radiofrequency for Refractory Migraine Treatment · PMID 35… | Migraine | Ralentissement de la progression · Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Ultrasound (US) guided pulsed radiofrequency (PRF) therapy can be used on the greater occipital nerve (GON) in patients… | Acta neurologica Belgica 2026-08-08 00:59:33 | Source |
| Evidence-Based Patient Selection in Headache Surgery: Impact of Preop… Efficacy of Greater Occipital Nerve Radiofrequency for Refractory Migraine Treatment · PMID 36… | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Radiofrequency ablation (RFA) of the greater occipital nerve (GON) is a minimally invasive treatment option commonly us… | Plastic and reconstructive surgery 2026-08-08 00:59:33 | Source |
| Peripheral Neuromodulation for the Management of Headache. Cefaly device · PMID 34150578 | Migraine | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Neuromodulation is an expanding field of study for headache treatment to reduce pain by targeting structures within the… | Anesthesiology and pain medicine 2026-08-08 00:59:33 | Source |
| Phentermine/Topiramate in Obese, Diabetic Uric Acid Stone Formers: An… Topiramate 100 mg · PMID 42361212 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source The purpose of this study was to determine whether medical treatment of obesity, diabetes, and low urine pH with combin… | The Journal of urology 2026-08-08 00:59:31 | Source |
| Use of obesity medications in a young pediatric patient with optic ne… Topiramate 100 mg · PMID 40698016 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Pediatric obesity presents complex challenges in children with underlying endocrine disorders. In patients with optic n… | Obesity pillars 2026-08-08 00:59:31 | Source |
| Atogepant Reduces Psychological Dependence on Acute Treatments Evalua… Atogepant 60 mg · PMID 42494172 | Migraine | À vérifier | Publication | PubMed | Voir la publication source The Leeds Dependence Questionnaire (LDQ) is a validated tool for assessing psychological dependence across various subs… | Brain and behavior 2026-08-08 00:59:30 | Source |
| Blood pressure lowering for prevention of episodic migraine: results… Propranolol 160 mg · PMID 41036277 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Beta blockers are effective in migraine prevention. Low-dose combination therapy of blood pressure lowering is likely t… | Frontiers in neurology 2026-08-08 00:59:30 | Source |
Exploration — prudence
Pistes exploratoires 5
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Bavisant BRAVEinMS — Bavisant | Migraine | Remyélinisation · Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Antagonisme du récepteur H3 de l’histamine Bavisant est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migra… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| Tol-MP Tol-MP — tolérance immunitaire spécifique de la myéline | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Microparticules biodégradables chargées en rapamycine et fonctionnalisées… Tol-MP est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migrain… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| SetPoint System SetPoint System — SetPoint Medical | Migraine | Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | re ApplicationsPublicationsCompanyCareersNewsGet startedGet startedNewsThe… SetPoint System est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation immunométabolique de la microglie 4-octyl itaconate et dérivés est étudié dans Sclérose latérale amyotrophique et documente plusieurs axes biologiques po… | Rapprochement Biomedical Watch · Sclérose latérale amy… | Détail |
| N-PPG N-PPG — modulation métabolique cérébrale | Migraine | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation métabolique et mitohormèse N-PPG est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être pertinents pour Migrai… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |