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Migraine
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
Périmètre
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1236 résultats correspondants
· 45 visibles sur cette page
dans le périmètre Migraine
Niveau clinique
Études et traitements 570
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Prospective ED Headache Cohort Study NCT00313703 · NCT00313703 | Migraine | Thérapie génique | À vérifier | COMPLETED | The purpose of this study is to determine how often headaches recur and to… À vérifier | ClinicalTrials.gov 2026-08-08 00:54:16 | Détail |
| ultrasound guided Greater occipital nerve block NCT06662461 · Ultrasound Guided Block of Stellate Ganglion Versus Greater Occipital Nerve in R… | Migraine | À vérifier | NA | RECRUITING | To investigate the efficacy of Ultrasound guided Stellate Ganglion block i… À vérifier | ClinicalTrials.gov 2026-08-08 00:54:16 | Détail |
| Visual Stimulation NCT02564822 · Effects of the Visual Stimulation on the Motor and Visual Cortex in Migraneurs W… | Migraine | À vérifier | À vérifier | COMPLETED | The aim of this study is to investigate the motor and visual cortex excita… À vérifier | ClinicalTrials.gov 2026-08-08 00:54:16 | Détail |
| Galcanezumab NCT02614261 · REGAIN — Evaluation of Galcanezumab in the Prevention of Chronic Migraine | Migraine | À vérifier | Phase 3 | COMPLETED | The main purpose of this study is to evaluate the efficacy of the study dr… À vérifier | ClinicalTrials.gov 2026-08-08 00:54:15 | Détail |
| Atogepant 60 mg NCT07699549 · GEMA PROJECT — Long-term Atogepant in Real-world Practice | Migraine | À vérifier | À vérifier | COMPLETED | This goal of this study is to compare three medications used for migraine… À vérifier | ClinicalTrials.gov 2026-08-05 21:16:03 | Détail |
| Occipital Nerve Stimulation NCT00200109 · ONSTIM — Occipital Nerve Stimulation for the Treatment of Chronic Migraine Heada… | Migraine | À vérifier | Phase 1 | COMPLETED | Background: Medically intractable chronic migraine (CM) is a disabling ill… À vérifier | ClinicalTrials.gov 2026-08-05 21:16:03 | Détail |
| TI-001 NCT01839149 · TI-001 (Intranasal Oxytocin) for Treatment of High Frequency Episodic Migraine a… | Migraine | À vérifier | Phase 2 | COMPLETED | This study evaluates the use of oxytocin, given as a nasal spray, for trea… À vérifier | ClinicalTrials.gov 2026-08-05 21:16:03 | Détail |
| a blood withdrawal will be obtained NCT07518069 · Menière09 — Genetic and Biohumoral Factors Involved in Menière's Disease and The… | Migraine | À vérifier | À vérifier | RECRUITING | Aim of this work was to assess the role of polymorphisms belonging to gene… À vérifier | ClinicalTrials.gov 2026-08-05 21:16:02 | Détail |
| gammaCore-S NCT02686034 · RCT of Non-Invasive Vagus Nerve Stimulation (nVNS) With gammaCore®, for the Acut… | Migraine | À vérifier | NA | COMPLETED | This study is a prospective, multi-centre, randomised, double-blind, sham-… À vérifier | ClinicalTrials.gov 2026-08-05 21:16:02 | Détail |
| Nerivio ® NCT05730556 · A Study of Remote Electrical Neuromodulation for Acute Procedural Pain | Migraine | Traitement symptomatique | NA | TERMINATED | The purpose of this study is to assess the effectiveness of using remote e… À vérifier | ClinicalTrials.gov 2026-08-05 21:16:02 | Détail |
| NXN-188 NCT00920686 · Study of NXN 188 for the Treatment of Migraine With Aura | Migraine | À vérifier | Phase 2 | COMPLETED | NXN-188 Dihydrochloride is being developed as an immediate release oral pr… À vérifier | ClinicalTrials.gov 2026-08-05 21:16:02 | Détail |
| OPAMA — Oxygenation and Perfusion in Patients With Acute Migraine Att… NCT03536936 · NCT03536936 | Migraine | À vérifier | À vérifier | COMPLETED | The aim of the study is to retrospectively evaluate brain perfusion and ox… À vérifier | ClinicalTrials.gov 2026-08-05 21:16:02 | Détail |
| Vestibular System in Migrainous Vertigo Patients NCT00901953 · NCT00901953 | Migraine | Traitement symptomatique | À vérifier | UNKNOWN | Do migrainous vertigo patients have more pathology in their vestibular sys… À vérifier | ClinicalTrials.gov 2026-08-05 21:16:02 | Détail |
| AI-assisted Migraine Education: Efficacy, Safety and Patients' Accept… NCT06507150 · NCT06507150 | Migraine | À vérifier | NA | RECRUITING | Migraine affects 1 in 7 people globally, significantly impacting quality o… À vérifier | ClinicalTrials.gov 2026-08-05 21:16:01 | Détail |
| A Ketogenic Diet Acts on Cortical But Not Subcortical Responsivity in… NCT03775252 · NCT03775252 | Migraine | Traitement symptomatique | NA | COMPLETED | A short ketogenic diet (KD) treatment can prevent migraine attacks and cor… À vérifier | ClinicalTrials.gov 2026-08-05 21:16:01 | Détail |
| Greater Occipital Nerve Block with dexamethasone and lidocaine NCT05679765 · Efficacy of GONB in Patients of Migraine | Migraine | Traitement symptomatique | Phase 4 | COMPLETED | The study was carried to determine the analgesic efficacy of greater occip… À vérifier | ClinicalTrials.gov 2026-08-05 21:16:01 | Détail |
| Migraine surgery NCT04008303 · Outcomes of Migraine Surgery | Migraine | Traitement symptomatique | À vérifier | WITHDRAWN | Migraines are very common and affect over 35 million Americans a year. Mig… À vérifier | ClinicalTrials.gov 2026-08-05 21:16:01 | Détail |
| Part A: TRV250-20mg/ml NCT04201080 · A Trial to Evaluate the Efficacy, Safety and Tolerability of Subcutaneous TRV250 | Migraine | À vérifier | Phase 1 | TERMINATED | A trial to assess the efficacy, safety, tolerability and effect of a drug… À vérifier | ClinicalTrials.gov 2026-08-05 21:16:01 | Détail |
| PROMPT-IN — A Study of Prophylaxis for Migraine Patients With Topiram… NCT01836874 · NCT01836874 | Migraine | À vérifier | À vérifier | COMPLETED | The purpose of this study is to evaluate the safety and effectiveness of t… À vérifier | ClinicalTrials.gov 2026-08-05 21:16:01 | Détail |
| tDCS device from neuroConn NCT03237754 · Neurostimulation in Chronic and Episodic Migraine | Migraine | Traitement symptomatique · Thérapie génique | NA | TERMINATED | Currently, successful prevention of migraine is not sufficiently achieved… À vérifier | ClinicalTrials.gov 2026-08-05 21:16:01 | Détail |
Découverte scientifique
Recherches et trouvailles 0
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune trouvaille ne correspond aux filtres. | |||||||
Bibliographie
Publications 661
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Amylin Coexisting With Peptide YY (PYY) and Amylin/PYY Cells Correspo… Amylin · PMID 42559671 | Migraine | Immunomodulation | Publication | PubMed | Voir la publication source The distribution of amylin-like substances was investigated by immunohistochemistry in the pancreas of the Japanese eel… | Anatomia, histologia, embryologia 2026-08-08 00:58:52 | Source |
| Acute effects of "exercise snacks" on postprandial glucose and insuli… Endothelin-1 · PMID 42558375 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source Exercise snacks-short, frequent bouts of physical activity that interrupt prolonged sitting-improve postprandial glucos… | Frontiers in endocrinology 2026-08-08 00:58:51 | Source |
| Hypoxemia with atelectasis during clazosentan therapy after subarachn… Endothelin-1 · PMID 42558750 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Clazosentan, a selective endothelin-A (ET-A) receptor antagonist, is used to prevent cerebral vasospasm after aneurysma… | Nagoya journal of medical science 2026-08-08 00:58:51 | Source |
| Emerging Neurovascular Interventions for the Prevention of Cerebral V… Cilostazol · PMID 42540693 | Migraine | Neuroprotection · Immunomodulation | Publication | PubMed | Voir la publication source Aneurysmal subarachnoid hemorrhage remains a major cause of neurological morbidity and mortality, with delayed cerebral… | Cureus 2026-08-08 00:58:50 | Source |
| Isosorbide Mononitrate/Cilostazol for Lacunar Cerebral Small Vessel D… Cilostazol · PMID 42535538 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Lacunar stroke can cause cognitive decline and dependency. The LACI-2 (Lacunar Intervention Trial-2) trial showed that… | Journal of the American Heart Association 2026-08-08 00:58:50 | Source |
| Twelve-months prospective real-world assessment of effectiveness and… Eptinezumab 100 mg or Eptinezumab 300 mg administered intravenously in 100 mL saline solution… | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Randomized clinical trials have demonstrated the efficacy and safety of eptinezumab. The aim of this study was to evalu… | The journal of headache and pain 2026-08-08 00:58:47 | Source |
| Targeting G-coupled GPCRs to inhibit nociceptors: Insights from the s… Triptan · PMID 42532046 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Pain perception is initiated upon activation of nociceptors of the dorsal root ganglia (DRG) and trigeminal ganglia. We… | Cell reports. Medicine 2026-08-08 00:58:45 | Source |
| Gastrointestinal Ascariasis: Unusual Presentation in 2 Cases. Non-steroidal anti-inflammatory drug (NSAID) · PMID 42540124 | Migraine | Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Ascariasis is a helminthic infection caused by the nematode and remains the most prevalent helminth infection worldwide… | Nigerian medical journal : journal of the Nigeria Medi… 2026-08-08 00:58:44 | Source |
| Impact of semaglutide introduction on the use of triptans: an interru… Triptan · PMID 42557547 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Emerging evidence suggests that glucagon-like peptide-1 receptor agonist (GLP-1RA) may be associated with reduced migra… | The journal of headache and pain 2026-08-08 00:58:44 | Source |
| In Vitro Evaluation of Lornoxicam Liquitablets: Permeability, Anti-In… Non-steroidal anti-inflammatory drug (NSAID) · PMID 42546887 | Migraine | Immunomodulation · Thérapie génique | Publication | PubMed | Voir la publication source Lornoxicam (LXM) is a potent non-steroidal anti-inflammatory drug (NSAID), characterised by low aqueous solubility, whi… | European journal of pharmaceutical sciences : official… 2026-08-08 00:58:44 | Source |
| Botulinum toxin in peripheral facial paralysis: systematic review and… Onabotulinum toxin A · PMID 42517166 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Peripheral facial paralysis (PFP) causes both static and dynamic facial dysfunctions, leading to synkinesis, hypertonia… | European journal of physical and rehabilitation medici… 2026-08-08 00:58:43 | Source |
| Repeated botulinum toxin injections for neurogenic thoracic outlet sy… Onabotulinum toxin A · PMID 42550976 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Neurogenic thoracic outlet syndrome (nTOS) is a condition caused by compression of the brachial plexus in the thoracic… | Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = T… 2026-08-08 00:58:43 | Source |
| Projected budget impact of pharmacotherapy scenarios for obesity and… topiramate · PMID 42565180 | Migraine | À vérifier | Publication | PubMed | Voir la publication source The increasing prevalence of obesity is generating demand for chronic pharmacologic treatment, but Latin American evide… | Obesity pillars 2026-08-08 00:58:42 | Source |
| Weight mitigation and tolerability of adjunctive topiramate in acute… topiramate · PMID 42558898 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Psychotropic medications are often associated with significant and rapid weight gain in pediatric populations, especial… | Frontiers in psychiatry 2026-08-08 00:58:42 | Source |
| Feasibility of Emotional Awareness and Expression Therapy Adapted for… Exploring Clinical Trial Experiences of Patients With Migraine · PMID 41742651 | Migraine | Ralentissement de la progression | Publication | PubMed | Voir la publication source Chronic headache, including migraine, is often associated with psychiatric conditions and adverse childhood experiences… | The Canadian journal of neurological sciences. Le jour… 2026-08-08 00:58:38 | Source |
| Physical Therapy Targeting Autonomic and Dura Mater Function: SPINEPA… Exploring Clinical Trial Experiences of Patients With Migraine · PMID 41324433 | Migraine | Ralentissement de la progression · Traitement symptomatique | Publication | PubMed | Voir la publication source Persistent post-traumatic headache (PPTH) or concussion is a significant United States military problem, and pharmacolo… | Physical therapy 2026-08-08 00:58:38 | Source |
| Efficacy and safety of gepants in migraine management: a narrative re… Rimegepant 75 MG · PMID 42548099 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Gepants, oral antagonists of the calcitonin gene-related peptide (CGRP) receptor, represent a new therapeutic class in… | Journal of oral & facial pain and headache 2026-08-08 00:58:35 | Source |
| Diagnostic value of shear wave elastography in assessing the effectiv… Botulinum toxin type A · PMID 42566101 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source Complex W3 ventral hernias with loss of domain (LOD) pose challenges in abdominal wall reconstruction due to pathologic… | Hernia : the journal of hernias and abdominal wall sur… 2026-08-08 00:58:34 | Source |
| [Treatment persistence and adherence with botulinum toxin type A and… Botulinum toxin type A · PMID 42565401 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source To compare the treatment persistence and adherence with botulinum toxin type A (Relatox; BTA) and monoclonal antibodies… | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 2026-08-08 00:58:34 | Source |
| Multi-organ AI endophenotypes chart the heterogeneity of brain, eye a… Digoxin · PMID 42559122 | Migraine | Ralentissement de la progression · Thérapie génique | Publication | PubMed | Voir la publication source Disease heterogeneity and commonality pose significant challenges to precision medicine, as traditional approaches freq… | Nature. Mental health 2026-08-08 00:57:54 | Source |
Exploration — prudence
Pistes exploratoires 5
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Bavisant BRAVEinMS — Bavisant | Migraine | Remyélinisation · Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Antagonisme du récepteur H3 de l’histamine Bavisant est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migra… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| Tol-MP Tol-MP — tolérance immunitaire spécifique de la myéline | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Microparticules biodégradables chargées en rapamycine et fonctionnalisées… Tol-MP est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migrain… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| SetPoint System SetPoint System — SetPoint Medical | Migraine | Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | re ApplicationsPublicationsCompanyCareersNewsGet startedGet startedNewsThe… SetPoint System est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation immunométabolique de la microglie 4-octyl itaconate et dérivés est étudié dans Sclérose latérale amyotrophique et documente plusieurs axes biologiques po… | Rapprochement Biomedical Watch · Sclérose latérale amy… | Détail |
| N-PPG N-PPG — modulation métabolique cérébrale | Migraine | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation métabolique et mitohormèse N-PPG est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être pertinents pour Migrai… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |