Vue transversale de la maladie
Migraine
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
Périmètre
Filtrer toute la vue
Chaque choix s’applique immédiatement aux quatre sections. Le filtre « type de SEP » n’apparaît que lorsque la sclérose en plaques est sélectionnée.
1236 résultats correspondants
· 45 visibles sur cette page
dans le périmètre Migraine
Niveau clinique
Études et traitements 570
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Prospective ED Headache Cohort Study NCT00313703 · NCT00313703 | Migraine | Thérapie génique | À vérifier | COMPLETED | The purpose of this study is to determine how often headaches recur and to… À vérifier | ClinicalTrials.gov 2026-08-08 00:54:16 | Détail |
| ultrasound guided Greater occipital nerve block NCT06662461 · Ultrasound Guided Block of Stellate Ganglion Versus Greater Occipital Nerve in R… | Migraine | À vérifier | NA | RECRUITING | To investigate the efficacy of Ultrasound guided Stellate Ganglion block i… À vérifier | ClinicalTrials.gov 2026-08-08 00:54:16 | Détail |
| Visual Stimulation NCT02564822 · Effects of the Visual Stimulation on the Motor and Visual Cortex in Migraneurs W… | Migraine | À vérifier | À vérifier | COMPLETED | The aim of this study is to investigate the motor and visual cortex excita… À vérifier | ClinicalTrials.gov 2026-08-08 00:54:16 | Détail |
| Galcanezumab NCT02614261 · REGAIN — Evaluation of Galcanezumab in the Prevention of Chronic Migraine | Migraine | À vérifier | Phase 3 | COMPLETED | The main purpose of this study is to evaluate the efficacy of the study dr… À vérifier | ClinicalTrials.gov 2026-08-08 00:54:15 | Détail |
| Atogepant 60 mg NCT07699549 · GEMA PROJECT — Long-term Atogepant in Real-world Practice | Migraine | À vérifier | À vérifier | COMPLETED | This goal of this study is to compare three medications used for migraine… À vérifier | ClinicalTrials.gov 2026-08-05 21:16:03 | Détail |
| Occipital Nerve Stimulation NCT00200109 · ONSTIM — Occipital Nerve Stimulation for the Treatment of Chronic Migraine Heada… | Migraine | À vérifier | Phase 1 | COMPLETED | Background: Medically intractable chronic migraine (CM) is a disabling ill… À vérifier | ClinicalTrials.gov 2026-08-05 21:16:03 | Détail |
| TI-001 NCT01839149 · TI-001 (Intranasal Oxytocin) for Treatment of High Frequency Episodic Migraine a… | Migraine | À vérifier | Phase 2 | COMPLETED | This study evaluates the use of oxytocin, given as a nasal spray, for trea… À vérifier | ClinicalTrials.gov 2026-08-05 21:16:03 | Détail |
| a blood withdrawal will be obtained NCT07518069 · Menière09 — Genetic and Biohumoral Factors Involved in Menière's Disease and The… | Migraine | À vérifier | À vérifier | RECRUITING | Aim of this work was to assess the role of polymorphisms belonging to gene… À vérifier | ClinicalTrials.gov 2026-08-05 21:16:02 | Détail |
| gammaCore-S NCT02686034 · RCT of Non-Invasive Vagus Nerve Stimulation (nVNS) With gammaCore®, for the Acut… | Migraine | À vérifier | NA | COMPLETED | This study is a prospective, multi-centre, randomised, double-blind, sham-… À vérifier | ClinicalTrials.gov 2026-08-05 21:16:02 | Détail |
| Nerivio ® NCT05730556 · A Study of Remote Electrical Neuromodulation for Acute Procedural Pain | Migraine | Traitement symptomatique | NA | TERMINATED | The purpose of this study is to assess the effectiveness of using remote e… À vérifier | ClinicalTrials.gov 2026-08-05 21:16:02 | Détail |
| NXN-188 NCT00920686 · Study of NXN 188 for the Treatment of Migraine With Aura | Migraine | À vérifier | Phase 2 | COMPLETED | NXN-188 Dihydrochloride is being developed as an immediate release oral pr… À vérifier | ClinicalTrials.gov 2026-08-05 21:16:02 | Détail |
| OPAMA — Oxygenation and Perfusion in Patients With Acute Migraine Att… NCT03536936 · NCT03536936 | Migraine | À vérifier | À vérifier | COMPLETED | The aim of the study is to retrospectively evaluate brain perfusion and ox… À vérifier | ClinicalTrials.gov 2026-08-05 21:16:02 | Détail |
| Vestibular System in Migrainous Vertigo Patients NCT00901953 · NCT00901953 | Migraine | Traitement symptomatique | À vérifier | UNKNOWN | Do migrainous vertigo patients have more pathology in their vestibular sys… À vérifier | ClinicalTrials.gov 2026-08-05 21:16:02 | Détail |
| AI-assisted Migraine Education: Efficacy, Safety and Patients' Accept… NCT06507150 · NCT06507150 | Migraine | À vérifier | NA | RECRUITING | Migraine affects 1 in 7 people globally, significantly impacting quality o… À vérifier | ClinicalTrials.gov 2026-08-05 21:16:01 | Détail |
| A Ketogenic Diet Acts on Cortical But Not Subcortical Responsivity in… NCT03775252 · NCT03775252 | Migraine | Traitement symptomatique | NA | COMPLETED | A short ketogenic diet (KD) treatment can prevent migraine attacks and cor… À vérifier | ClinicalTrials.gov 2026-08-05 21:16:01 | Détail |
| Greater Occipital Nerve Block with dexamethasone and lidocaine NCT05679765 · Efficacy of GONB in Patients of Migraine | Migraine | Traitement symptomatique | Phase 4 | COMPLETED | The study was carried to determine the analgesic efficacy of greater occip… À vérifier | ClinicalTrials.gov 2026-08-05 21:16:01 | Détail |
| Migraine surgery NCT04008303 · Outcomes of Migraine Surgery | Migraine | Traitement symptomatique | À vérifier | WITHDRAWN | Migraines are very common and affect over 35 million Americans a year. Mig… À vérifier | ClinicalTrials.gov 2026-08-05 21:16:01 | Détail |
| Part A: TRV250-20mg/ml NCT04201080 · A Trial to Evaluate the Efficacy, Safety and Tolerability of Subcutaneous TRV250 | Migraine | À vérifier | Phase 1 | TERMINATED | A trial to assess the efficacy, safety, tolerability and effect of a drug… À vérifier | ClinicalTrials.gov 2026-08-05 21:16:01 | Détail |
| PROMPT-IN — A Study of Prophylaxis for Migraine Patients With Topiram… NCT01836874 · NCT01836874 | Migraine | À vérifier | À vérifier | COMPLETED | The purpose of this study is to evaluate the safety and effectiveness of t… À vérifier | ClinicalTrials.gov 2026-08-05 21:16:01 | Détail |
| tDCS device from neuroConn NCT03237754 · Neurostimulation in Chronic and Episodic Migraine | Migraine | Traitement symptomatique · Thérapie génique | NA | TERMINATED | Currently, successful prevention of migraine is not sufficiently achieved… À vérifier | ClinicalTrials.gov 2026-08-05 21:16:01 | Détail |
Découverte scientifique
Recherches et trouvailles 0
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune trouvaille ne correspond aux filtres. | |||||||
Bibliographie
Publications 661
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Efficacy of Greater Occipital Nerve Blockade in Craniofacial Neuralgi… Greater Occipital Nerve Block with dexamethasone and lidocaine · PMID 40725724 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source : Greater occipital nerve blockade (GONB) is a minimally invasive intervention used to treat primary headaches. However… | Journal of clinical medicine 2026-08-08 00:59:43 | Source |
| Greater occipital nerve blockade for the preventive treatment of chro… Greater Occipital Nerve Block with 0.9% saline · PMID 36739512 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Greater occipital nerve blockade for the prevention of chronic migraine has a limited evidence base. A robust randomize… | Cephalalgia : an international journal of headache 2026-08-08 00:59:43 | Source |
| Three men in a boat: The comparison of the combination therapy of bot… Greater Occipital Nerve Block with 0.9% saline · PMID 36731164 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source This study compared the impact of the combination therapy of onabotulinum toxin A and greater occipital nerve block (Go… | Clinical neurology and neurosurgery 2026-08-08 00:59:43 | Source |
| High dosage accelerated intermittent theta burst stimulation without… tDCS device from neuroConn · PMID 40705070 | Migraine | À vérifier | Publication | PubMed | Voir la publication source High dosage accelerated intermittent theta-burst stimulation (aiTBS) protocols (10 sessions per day for 5 days) combine… | European archives of psychiatry and clinical neuroscie… 2026-08-08 00:59:42 | Source |
| Report Approval for Transcranial Electrical Stimulation (RATES): expe… tDCS device from neuroConn · PMID 41044265 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Transcranial electrical stimulation (tES) has gained substantial momentum as a research and therapeutic tool; however,… | Nature protocols 2026-08-08 00:59:42 | Source |
| Artificial intelligence-based decision support in simulated free flap… Migraine surgery · PMID 42326044 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Free flap compromise after head and neck reconstruction requires rapid recognition and structured escalation. Large lan… | JPRAS open 2026-08-08 00:59:41 | Source |
| Corrugator Supercilii Muscle and Its Relationship with Neurovascular… Migraine surgery · PMID 42192010 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source The corrugator supercilii muscle (CSM) is a critical anatomical target for botulinum toxin injections and surgical inte… | Aesthetic plastic surgery 2026-08-08 00:59:41 | Source |
| Efficacy and tolerability of combination treatment of topiramate and… PROMPT-IN — A Study of Prophylaxis for Migraine Patients With Topiramate in India · PMID 35259… | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source To compare the efficacy and tolerability of combination treatment of topiramate and greater occipital nerve block to to… | Cephalalgia : an international journal of headache 2026-08-08 00:59:40 | Source |
| Vitamin D Deficiency and Supplementation in Migraine: A Scoping Revie… PROMPT-IN — A Study of Prophylaxis for Migraine Patients With Topiramate in India · PMID 41233… | Migraine | Ralentissement de la progression · Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Migraine is a debilitating neurological disorder affecting 10%-20% of the global population, with significant socioecon… | Annals of Indian Academy of Neurology 2026-08-08 00:59:40 | Source |
| A Phase I, Randomized, Single‑Blind, Placebo‑Controlled, Single Ascen… Part B: TRV250 Dose 1 · PMID 32676977 | Migraine | À vérifier | Publication | PubMed | Voir la publication source The delta opioid receptor (DOR) has been identified as a therapeutic target for migraine, with DOR agonists exhibiting… | CNS drugs 2026-08-08 00:59:37 | Source |
| Investigation of a foodborne outbreak of Shigella sonnei in Ireland a… Part A: TRV250-20mg/ml · PMID 32120067 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source To describe a cross-border foodborne outbreak of Shigella sonnei that occurred in Ireland and Northern Ireland (NI) in… | Public health 2026-08-08 00:59:36 | Source |
| Outbreak of hepatitis A infection associated with the consumption of… Part A: TRV250-20mg/ml · PMID 25375902 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source In May 2013, a European alert was issued regarding a hepatitis A virus (HAV) outbreak in Italy. In June 2013, HAV subge… | Euro surveillance : bulletin Europeen sur les maladies… 2026-08-08 00:59:36 | Source |
| Alterations of Resting-State Locus Coeruleus Functional Connectivity… Cefaly device · PMID 35619611 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Transdermal trigeminal electrical neuromodulation (TTEN) is a novel treatment modality that is known for noradrenergic… | Frontiers in psychiatry 2026-08-08 00:59:33 | Source |
| Efficacy of ultrasound-guided greater occipital nerve pulsed radiofre… Efficacy of Greater Occipital Nerve Radiofrequency for Refractory Migraine Treatment · PMID 35… | Migraine | Ralentissement de la progression · Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Ultrasound (US) guided pulsed radiofrequency (PRF) therapy can be used on the greater occipital nerve (GON) in patients… | Acta neurologica Belgica 2026-08-08 00:59:33 | Source |
| Evidence-Based Patient Selection in Headache Surgery: Impact of Preop… Efficacy of Greater Occipital Nerve Radiofrequency for Refractory Migraine Treatment · PMID 36… | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Radiofrequency ablation (RFA) of the greater occipital nerve (GON) is a minimally invasive treatment option commonly us… | Plastic and reconstructive surgery 2026-08-08 00:59:33 | Source |
| Peripheral Neuromodulation for the Management of Headache. Cefaly device · PMID 34150578 | Migraine | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Neuromodulation is an expanding field of study for headache treatment to reduce pain by targeting structures within the… | Anesthesiology and pain medicine 2026-08-08 00:59:33 | Source |
| Phentermine/Topiramate in Obese, Diabetic Uric Acid Stone Formers: An… Topiramate 100 mg · PMID 42361212 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source The purpose of this study was to determine whether medical treatment of obesity, diabetes, and low urine pH with combin… | The Journal of urology 2026-08-08 00:59:31 | Source |
| Use of obesity medications in a young pediatric patient with optic ne… Topiramate 100 mg · PMID 40698016 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Pediatric obesity presents complex challenges in children with underlying endocrine disorders. In patients with optic n… | Obesity pillars 2026-08-08 00:59:31 | Source |
| Atogepant Reduces Psychological Dependence on Acute Treatments Evalua… Atogepant 60 mg · PMID 42494172 | Migraine | À vérifier | Publication | PubMed | Voir la publication source The Leeds Dependence Questionnaire (LDQ) is a validated tool for assessing psychological dependence across various subs… | Brain and behavior 2026-08-08 00:59:30 | Source |
| Blood pressure lowering for prevention of episodic migraine: results… Propranolol 160 mg · PMID 41036277 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Beta blockers are effective in migraine prevention. Low-dose combination therapy of blood pressure lowering is likely t… | Frontiers in neurology 2026-08-08 00:59:30 | Source |
Exploration — prudence
Pistes exploratoires 5
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Bavisant BRAVEinMS — Bavisant | Migraine | Remyélinisation · Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Antagonisme du récepteur H3 de l’histamine Bavisant est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migra… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| Tol-MP Tol-MP — tolérance immunitaire spécifique de la myéline | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Microparticules biodégradables chargées en rapamycine et fonctionnalisées… Tol-MP est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migrain… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| SetPoint System SetPoint System — SetPoint Medical | Migraine | Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | re ApplicationsPublicationsCompanyCareersNewsGet startedGet startedNewsThe… SetPoint System est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation immunométabolique de la microglie 4-octyl itaconate et dérivés est étudié dans Sclérose latérale amyotrophique et documente plusieurs axes biologiques po… | Rapprochement Biomedical Watch · Sclérose latérale amy… | Détail |
| N-PPG N-PPG — modulation métabolique cérébrale | Migraine | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation métabolique et mitohormèse N-PPG est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être pertinents pour Migrai… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |