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Périmètre

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Chaque choix s’applique immédiatement aux quatre sections. Le filtre « type de SEP » n’apparaît que lorsque la sclérose en plaques est sélectionnée.

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Essais et traitements4050Données cliniques et programmes
Recherches et trouvailles21Pipeline scientifique
Publications4595Références reliées aux maladies
Pistes exploratoires0Hypothèses non validées
8666 résultats correspondants · 41 visibles sur cette page dans le périmètre Toutes les maladies
Niveau clinique

Études et traitements 4050

Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.

Molécule / élément Maladie / population Objectif Phase / stade Statut / preuve Mécanisme / résumé Source Détail
MUC-CFS — Munich ME/CFS Cohort Study NCT06005246 · NCT06005246 Myopathies Traitement symptomatique À vérifier RECRUITING The Munich cohort study MUC-CFS aims at the characterization and long-term… À vérifier ClinicalTrials.gov 2026-08-05 21:16:07 Détail
Sevasemten Dose 1 NCT06100887 · FOX — Phase 2 Study of EDG-5506 in Children and Adolescents With Duchenne Muscul… Myopathies Thérapie génique Phase 2 ACTIVE_NOT_RECRUITING The FOX study is a 2-part, multicenter, Phase 2 study of safety, pharmacok… À vérifier ClinicalTrials.gov 2026-08-05 21:16:07 Détail
Xeomin Injectable Product NCT04544280 · Effect of Repeated Injections of Higher Doses of Botulinum Toxin on Lower Limb o… Myopathies À vérifier NA COMPLETED 1. To show that repeated injections of higher doses of botulinum toxin are… À vérifier ClinicalTrials.gov 2026-08-05 21:16:07 Détail
68-Gallium DOTATATE NCT04074135 · Natural History and Management of Von Hippel-Lindau (VHL) Associated Pancreatic… Cancer Traitement symptomatique · Thérapie génique Phase 2 RECRUITING Background: People with von Hippel-Lindau (VHL) can have problems with a v… À vérifier ClinicalTrials.gov 2026-08-05 21:16:06 Détail
Early antibiotic cessation alert NCT07051525 · ELSA-Adult — Early Versus Late Stopping of Antibiotics in Adults With High-risk… Cancer Thérapie cellulaire NA RECRUITING Pre-neutropenic fever (PNF) (fever following chemotherapy but before devel… À vérifier ClinicalTrials.gov 2026-08-05 21:16:06 Détail
GP2 peptide + GM-CSF vaccine plus trastuzumab NCT03014076 · Immunotherapy Vaccine and Herceptin in Breast Cancer Cancer À vérifier Phase 1 COMPLETED The purpose of this trial is to determine if combination immunotherapy wit… À vérifier ClinicalTrials.gov 2026-08-05 21:16:06 Détail
GSK1550188 IV NCT01516450 · Japanese phase1 Study of Belimumab (IV vs SC) Lupus À vérifier Phase 1 COMPLETED This study is an open-label, randomized, 2 parallel group, single dose stu… À vérifier ClinicalTrials.gov 2026-08-05 21:16:06 Détail
Mini-AFTERc Intervention for Fear of Cancer Recurrence NCT03763825 · NCT03763825 Cancer À vérifier NA UNKNOWN People treated for breast cancer often live with an ongoing fear that the… À vérifier ClinicalTrials.gov 2026-08-05 21:16:06 Détail
Multicomponent Strategy to Implement a Clinical Practice Guideline an… NCT03537638 · NCT03537638 Lupus À vérifier NA COMPLETED Principal objective: To produce scientific knowledge on the effectiveness… À vérifier ClinicalTrials.gov 2026-08-05 21:16:06 Détail
NKX019 NCT06518668 · A Study of NKX019, a CD19 CAR NK Cell Therapy, in Subjects With Systemic Lupus E… Lupus Thérapie cellulaire Phase 1 ENROLLING_BY_INVITATION Primary objective: Safety and tolerability of NKX019, administered after l… À vérifier ClinicalTrials.gov 2026-08-05 21:16:06 Détail
Selinexor NCT02416908 · Study of CLAG + Selinexor in Relapsed or Refractory Acute Myeloid Leukemia Cancer Traitement symptomatique Phase 1 COMPLETED Selinexor has shown single-agent activity in a current phase I study enrol… À vérifier ClinicalTrials.gov 2026-08-05 21:16:06 Détail
Sirolimus NCT00050713 · Sirolimus Therapy for Idiopathic and Lupus Membranous Nephropathy Lupus Traitement symptomatique Phase 2 COMPLETED This study will evaluate the safety and effectiveness of a new immunosuppr… À vérifier ClinicalTrials.gov 2026-08-05 21:16:06 Détail
Urinary T Cell Biomarker for Prediction in Lupus Nephritis NCT04320797 · NCT04320797 Lupus Immunomodulation À vérifier UNKNOWN Urinary T-lymphocytes may be predictive for clinical outcome in patients w… À vérifier ClinicalTrials.gov 2026-08-05 21:16:06 Détail
BR1019 NCT06226727 · A Study to Evaluate the Pharmacokinetics and the Safety After Administration of… Hypertension artérielle À vérifier Phase 1 COMPLETED The objective of this clinical study is to evaluate the pharmacokinetics a… À vérifier ClinicalTrials.gov 2026-08-05 21:16:05 Détail
CONSULT-BP — COmmuNity-engaged SimULation Training for Blood Pressure… NCT03375918 · NCT03375918 Hypertension artérielle À vérifier NA COMPLETED The goal of CONSULT-BP is to train early-stage healthcare providers, inclu… À vérifier ClinicalTrials.gov 2026-08-05 21:16:05 Détail
Diabetes and Hypertension Self Management Program NCT06034548 · NCT06034548 Hypertension artérielle À vérifier NA COMPLETED The purpose of this R15 project is to test the feasibility and effectivene… À vérifier ClinicalTrials.gov 2026-08-05 21:16:05 Détail
Effects of Xoçai Antioxidant Supplements on Atherosclerosis Risk Fact… NCT00666250 · NCT00666250 Hypertension artérielle À vérifier NA COMPLETED An antioxidant dietary supplement made from cocoa powder, and extracts of… À vérifier ClinicalTrials.gov 2026-08-05 21:16:05 Détail
Fimasartan/Amlodipine NCT02920047 · A Clinical Trial to Evaluate the Pharmacokinetics and Safety of Fimasartan and A… Hypertension artérielle À vérifier Phase 1 COMPLETED The purpose of this study is to evaluate the pharmacokinetics and safety w… À vérifier ClinicalTrials.gov 2026-08-05 21:16:05 Détail
Indapamide (T2) NCT00128518 · IDEAL Study: Identification of the Determinants of the Efficacy of Arterial Bloo… Hypertension artérielle À vérifier Phase 4 COMPLETED The principal scientific objective of the trial is to identify the factors… À vérifier ClinicalTrials.gov 2026-08-05 21:16:05 Détail
RCT Examining Effects of Probiotics in T2DM Individuals NCT01752803 · NCT01752803 Hypertension artérielle À vérifier NA UNKNOWN Background: The connection between gut health and diabetes status is incre… À vérifier ClinicalTrials.gov 2026-08-05 21:16:05 Détail
Découverte scientifique

Recherches et trouvailles 21

Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.

Molécule / élément Maladie / population Objectif Phase / stade Statut / preuve Mécanisme / résumé Source Détail
4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation Sclérose latérale amyotrophique Neuroprotection · Immunomodulation Découverte fondamentale Exploratoire Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… Revue scientifique 2024-07-01 Détail
Bibliographie

Publications 4595

Références bibliographiques de la base locale et accès à leur source originale.

Molécule / élément Maladie / population Objectif Phase / stade Statut / preuve Mécanisme / résumé Source Détail
Effects of testosterone-augmented multimodal exercise intervention in… Whole-body Electrical Muscle Stimulation Exercise · PMID 41988780 Myasthénie À vérifier Publication PubMed Voir la publication source Spinal cord injury (SCI) leads to profound muscle atrophy, aerobic deconditioning, and metabolic dysfunction. Exercise-… The Journal of clinical endocrinology and metabolism 2026-09-20 04:37:05 Source
Feasibility and acceptability of whole-body electromyostimulation in… Whole-body Electrical Muscle Stimulation Exercise · PMID 42464389 Myasthénie À vérifier Publication PubMed Voir la publication source Evidence on the effectiveness of electromyostimulation (EMS) has been reported in pulmonary rehabilitation, but the ben… Pilot and feasibility studies 2026-09-20 04:37:05 Source
Vestibular contributions adapt to the balance strategies adopted duri… Whole-body Electrical Muscle Stimulation Exercise · PMID 42616645 Myasthénie À vérifier Publication PubMed Voir la publication source Vestibular contributions during walking are not uniform, but vary with gait phase, muscle group, and balance demands. M… Journal of neurophysiology 2026-09-20 04:37:05 Source
Clinical efficacy of abdominal moxibustion at the Zhongji (CV3) in co… Yangyin Roujin Decoction · PMID 42015783 Myopathies Neuroprotection · Traitement symptomatique Publication PubMed Voir la publication source To investigate the clinical effect of abdominal moxibustion at the Zhongji (CV3) combined with Yiqi Tonglin Yangyin dec… Journal of traditional Chinese medicine = Chung i tsa… 2026-09-20 04:37:03 Source
Yiqi Huoxue Yangyin Decoction Ameliorates Diabetic Nephropathy by Tar… Yangyin Roujin Decoction · PMID 42713045 Myopathies À vérifier Publication PubMed Voir la publication source This study aimed to investigate the protective effects and underlying mechanisms of Yiqi Huoxue Yangyin Decoction (YHY)… Diabetes, metabolic syndrome and obesity : targets and… 2026-09-20 04:37:03 Source
Yiqi Huoxue Yangyin Decoction attenuates diabetic nephropathy in mice… Yangyin Roujin Decoction · PMID 42016924 Myopathies Thérapie génique Publication PubMed Voir la publication source Diabetic nephropathy (DN) is a major complication of diabetes with limited therapeutic options. Yiqi Huoxue Yangyin Dec… Frontiers in pharmacology 2026-09-20 04:37:03 Source
Barcoded oligonucleotide system (BOLT) for targeted organ delivery. Immunotherapy · PMID 42733790 Cancer À vérifier Publication PubMed Voir la publication source The therapeutic potential of oligonucleotides (oligos) is limited by insufficient delivery to extrahepatic tissues. In… Bioactive materials 2026-09-20 04:36:56 Source
Dual metabolic checkpoint blockade a 3D-Printed metalloplatform remod… Immunotherapy · PMID 42724565 Cancer Immunomodulation Publication PubMed Voir la publication source The immunosuppressive tumor microenvironment limits the efficacy of therapies that target metabolism. Here we show a st… Bioactive materials 2026-09-20 04:36:56 Source
Oligosaccharide adjuvant-deferred antigen endocytosis promotes cross-… Immunotherapy · PMID 42751513 Cancer Immunomodulation · Thérapie génique Publication PubMed Voir la publication source Antigen cross-presentation by dendritic cells (DCs) is essential for inducing cytotoxic immune responses, which are cru… Bioactive materials 2026-09-20 04:36:56 Source
Feasibility and safety of early discharge after robot-assisted uro-on… Digital care pathway for hypertension · PMID 42671715 Hypertension artérielle À vérifier Publication PubMed Voir la publication source Early discharge after robot-assisted uro-oncologic surgery remains limited by concerns regarding patient safety and the… Journal of robotic surgery 2026-09-20 04:36:49 Source
HomeSafe: Postpartum Hypertensive Care Enabled by Electronic Health R… Digital care pathway for hypertension · PMID 41707683 Hypertension artérielle À vérifier Publication PubMed Voir la publication source The objective is to present stepwise refinements to , an Epic-tethered, population-health-coordinated postpartum pathwa… American journal of perinatology 2026-09-20 04:36:49 Source
Nutraceutical and functional food: efficacy against metabolic disorde… Digital care pathway for hypertension · PMID 42603698 Hypertension artérielle Neuroprotection · Immunomodulation Publication PubMed Voir la publication source The growing global emphasis on health consciousness has significantly increased demand for traditional and complementar… Journal of advanced research 2026-09-20 04:36:49 Source
Community-engaged design of a virtual diabetes prevention program int… Asynchronous communication with nurse · PMID 42288862 Hypertension artérielle À vérifier Publication PubMed Voir la publication source The Diabetes Prevention Program (DPP) is an evidence-based approach to prevent Type 2 Diabetes (T2D), the leading cause… BMC health services research 2026-09-20 04:36:48 Source
Evolving Lung Cancer Navigator Practice Through Targeted Professional… Asynchronous communication with nurse · PMID 42463006 Cancer À vérifier Publication PubMed Voir la publication source Lung cancer remains the leading cause of cancer deaths worldwide, and it has persistent disparities in detection, treat… Chest 2026-09-20 04:36:48 Source
Mass casualty training for prehospital and emergency providers in Kig… Asynchronous communication with nurse · PMID 42751142 Hypertension artérielle À vérifier Publication PubMed Voir la publication source A mass casualty incident (MCI) occurs when the number of patients exceeds available healthcare resources, placing signi… African journal of emergency medicine : Revue africain… 2026-09-20 04:36:48 Source
Innovating a Teach-Back Model for Community Health Workers Led Health… Health Literacy Project · PMID 40194526 Épilepsie À vérifier Publication PubMed Voir la publication source From 2021 to 2023, the City of Albuquerque, the University of New Mexico (UNM) Office for Community Health, the UNM Hos… Health literacy research and practice 2026-09-20 04:36:34 Source
Carotid intima-media thickness may be an early biomarker for cardiova… Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy · PMID 41026111 Épilepsie À vérifier Publication PubMed Voir la publication source To assess early signs of atherosclerosis following long-term treatment with the ketogenic diet therapy due to concerns… Epilepsia open 2026-09-20 04:36:33 Source
Impact of low-carbohydrate diet on health status: an umbrella review. Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy · PMID 39385794 Cancer À vérifier Publication PubMed Voir la publication source The prevalence of diet-related non-communicable diseases has increased. A low-carbohydrate diet (LCDs) is one of the mo… Frontiers in nutrition 2026-09-20 04:36:33 Source
The effect of anti-seizure medications on lipid values in adults with… Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy · PMID 37244221 Épilepsie À vérifier Publication PubMed Voir la publication source Certain anti-seizure medications (ASMs) adversely impact lipid values. Here, we explored the impact of ASMs on lipid va… Epilepsy & behavior : E&B 2026-09-20 04:36:33 Source
Possible role of locus coeruleus neuronal loss in age-related memory… The Role of the Locus Coeruleus in Age-related Distractibility · PMID 37694113 Maladie d’Alzheimer Immunomodulation Publication PubMed Voir la publication source Aging is associated with a decline in cognitive abilities, including memory and attention. It is generally accepted tha… Frontiers in neuroscience 2026-09-20 04:36:30 Source
Exploration — prudence

Pistes exploratoires 0

Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.

Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
Molécule / élément Maladie / population Objectif Phase / stade Statut / preuve Mécanisme / résumé Source Détail
Aucune piste exploratoire ne correspond aux filtres.