Vue transversale de la maladie
Migraine
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
Périmètre
Filtrer toute la vue
Chaque choix s’applique immédiatement aux quatre sections. Le filtre « type de SEP » n’apparaît que lorsque la sclérose en plaques est sélectionnée.
1236 résultats correspondants
· 45 visibles sur cette page
dans le périmètre Migraine
Niveau clinique
Études et traitements 570
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Caffeine (200 mg) NCT07022496 · Assessment of Oral Caffeine Intake in Changing the Severity of Acute Migraine At… | Migraine | À vérifier | Phase 4 | RECRUITING | Caffeine extracted from green tea to abort acute attack of Migraine À vérifier | ClinicalTrials.gov 2026-08-13 14:17:14 | Détail |
| HELP-VM — Healthy Living Partnerships for Veterans With Migraine NCT04373330 · NCT04373330 | Migraine | Traitement symptomatique | Non applicable | WITHDRAWN | This pilot study, modeled upon the successful and empirically validated HE… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:14 | Détail |
| Partial Rebreathing Device NCT05546385 · PAREMA1 — PArtial REbreathing for Migraine With Aura 1 | Migraine | À vérifier | Non applicable | TERMINATED | A prospective, multi-centre, randomized, double-blind, sham-controlled, pa… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:14 | Détail |
| Active drug for chronic migraine treatment. NCT07071506 · New Methods for Evaluating Preventive Migraine Treatment | Migraine | À vérifier | Non applicable | RECRUITING | The study aims to test interactions between drug and placebo-responses in… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Actual device PFO closure NCT04100135 · RELIEF — GORE® CARDIOFORM Septal Occluder Migraine Clinical Study | Migraine | À vérifier | Non applicable | TERMINATED | Multi-center, prospective, randomized, placebo- and sham-controlled study… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| ACU-BRAIN — Brain Connectome for Acupuncture-treated Migraine Patients NCT04157192 · NCT04157192 | Migraine | Traitement symptomatique | Non applicable | COMPLETED | Acupuncture has been a means of treating headaches and migraine since 2002… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| ACUPMIGRAINE — The Impact of Acupuncture on Biomarkers of Brain Injur… NCT07292506 · NCT07292506 | Migraine | Immunomodulation · Traitement symptomatique | Non applicable | ACTIVE_NOT_RECRUITING | Migraine is more than just a headache-it can involve changes in the brain… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Amiloride NCT04063540 · APAM — Acid-Sensing Ion Channel and Migraine Disease Proof of Concept Study on t… | Migraine | À vérifier | Phase 2 | RECRUITING | Recent data suggest involvement of Acid-Sensing Ion Channel channels in th… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| App-Based Migraine Treatment: The Health enSuite Study NCT06797076 · NCT06797076 | Migraine | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | Health enSuite is a suite of applications designed by our research team at… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Atogepant 60 mg NCT06414044 · STAR — Italian Real-life obServational Study on the effecTiveness, sAfety and To… | Migraine | À vérifier | À vérifier | ACTIVE_NOT_RECRUITING | This goal of this study is to compare three medications used for migraine… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| BE WELL With Migraine: Brain Education and WELLness With Migraine NCT05987592 · NCT05987592 | Migraine | À vérifier | Non applicable | RECRUITING | The goal of this randomized clinical trial is to evaluate two different no… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Biodegradable occluder NCT06203873 · BioMetal — A Comparison of Biodegradable and Metal Occluders in Patients With PF… | Migraine | Traitement symptomatique | Non applicable | RECRUITING | Migraine is one of the most common chronic neurological disorders, posing… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Calcitonin-gene related peptide (CGRP) NCT07021859 · Induction of Migraine Attacks With Aura Using Calcitonin Gene-Related Peptide | Migraine | À vérifier | Non applicable | RECRUITING | Calcitonin gene-related peptide (CGRP) is a key neuropeptide in migraine p… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Clorazepate Dipotassium NCT04726592 · CLORMIG — Efficacy of CLORazepate for the Treatment of MIGraine Attack in the Em… | Migraine | À vérifier | Phase 3 | TERMINATED | The purpose of this study is to evaluate the efficacy of clorazepate in ad… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Exploring the Effect of the Transcendental Meditation® Technique on M… NCT06695156 · NCT06695156 | Migraine | À vérifier | Non applicable | COMPLETED | This research will explore the effect of the Transcendental Meditation® Te… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Levcromakalim NCT04853797 · Effect of Ivabradine on Levcromakalim-Induced Symptoms in Individuals With Migra… | Migraine | Traitement symptomatique | Non applicable | COMPLETED | This study aims to explore the effect of Ivabradine on Levcromakalim-induc… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Mi-Helper NCT06874361 · CALM3 — Cooling to Alleviate Migraine #3 | Migraine | À vérifier | Non applicable | COMPLETED | This is a prospective, double-blind, sham-controlled, randomized, decentra… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| MTX101 NCT06728553 · Safety and Efficacy Trial of MTX101 2mg for the Acute Treatment of Migraine in A… | Migraine | Traitement symptomatique · Thérapie génique | Phase 2 | COMPLETED | The goal of this clinical trial is to learn if drug MTX101 works to treat… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Nerivio device NCT06023953 · Migraine With and Without Aura Characteristics and Response to Remote Electrical… | Migraine | Traitement symptomatique | À vérifier | COMPLETED | This is a Post-marketing, real-world evidence study investigating the safe… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Neuromodulation Wearable Device NCT07642414 · A Comprehensive Digital Care Program for Migraine Management | Migraine | À vérifier | Non applicable | RECRUITING | This study evaluates the clinical effectiveness of the Enso for Migraine p… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
Découverte scientifique
Recherches et trouvailles 0
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune trouvaille ne correspond aux filtres. | |||||||
Bibliographie
Publications 661
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Stephanoside B modulates metabolic gene expression and lengthens the… dexamethasone · PMID 42484698 | Migraine | Immunomodulation | Publication | PubMed | Voir la publication source Gymnema (G.) inodorum is a medicinal plant with anti-diabetic, anti-obesity, and anti-inflammatory properties tradition… | Molecular biology reports 2026-07-22 21:21:52 | Source |
| Peripheral nerve stimulation registry for intractable migraine headac… Relief — Peripheral Nerve Stimulation Registry for Intractable Migraine Headache · PMID 323779… | Migraine | Ralentissement de la progression | Publication | PubMed | Voir la publication source Migraine is common and ranked as the first cause of disability in people under fifty. Despite significant advances in i… | Acta neurochirurgica 2026-07-22 21:21:32 | Source |
| Comparison of Balanced General Anesthesia Protocols in Sleeve Gastrec… ketamine infusion · PMID 42455083 | Migraine | À vérifier | Publication | PubMed | Voir la publication source To evaluate the effects of two different anesthesia management techniques applied to sleeve gastrectomy patients on pos… | Journal of perianesthesia nursing : official journal o… 2026-07-22 21:21:31 | Source |
| Innovative integration of high dose ketamine infusion, psychological… ketamine infusion · PMID 42454590 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Ketamine is a noncompetitive antagonist of the N-methyl-D-aspartate receptor that has garnered significant interest as… | Pain management 2026-07-22 21:21:31 | Source |
| Atorvastatin Reduces Alcohol-Related Cardiac and Liver Tissue Damage,… Endothelin-1 · PMID 42478929 | Migraine | Remyélinisation indirecte / réparation · Neuroprotection · Immunomodulation | Publication | PubMed | Voir la publication source Excessive alcohol consumption causes significant cardio-hepatic damage. This study investigated the effects of standard… | Journal of biochemical and molecular toxicology 2026-07-22 21:21:29 | Source |
| Involvement of Mitophagy in Endothelin-1 Mediated Neurodegeneration i… Endothelin-1 · PMID 42465463 | Migraine | Remyélinisation indirecte / réparation | Publication | PubMed | Voir la publication source The ultimate cause of blindness in glaucoma is the death of retinal ganglion cells, and understanding the mechanism beh… | bioRxiv : the preprint server for biology 2026-07-22 21:21:29 | Source |
| Connexin 43 subcellular localization: From trafficking dynamics to pa… Tonabersat · PMID 42069098 | Migraine | Remyélinisation indirecte / réparation · Immunomodulation | Publication | PubMed | Voir la publication source Connexin 43 (Cx43) exhibits remarkable functional diversity that is precisely dictated by its dynamic subcellular local… | Cellular signalling 2026-07-22 21:21:28 | Source |
| Oral Tonabersat Connexin-43 Modulator for Diabetic Macular Edema with… Tonabersat · PMID 42064012 | Migraine | Immunomodulation | Publication | PubMed | Voir la publication source Evaluate oral tonabersat, a connexin-43 hemichannel modulator, on central subfield thickness (CST) in eyes with center-… | Ophthalmology science 2026-07-22 21:21:28 | Source |
| Cross-response to Calcitonin Gene-Related Peptide monoclonal antibodi… Eptinezumab 100 mg or Eptinezumab 300 mg administered intravenously in 100 mL saline solution… | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Real-world data on calcitonin gene-related peptide (CGRP) monoclonal antibodies (mAbs) are essential to determine wheth… | The journal of headache and pain 2026-07-22 21:21:27 | Source |
| Long-term treatment with Eptinezumab in special treatment situations:… Eptinezumab 100 mg or Eptinezumab 300 mg administered intravenously in 100 mL saline solution… | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source The neurotransmitter Calcitonin Gene related Peptide (CGRP) is one of the key players driving migraine attacks. Randomi… | Journal of the neurological sciences 2026-07-22 21:21:27 | Source |
| Chronic Migraine Pathophysiology and Treatment: A Review of Current P… HYPOTHAMIG — Hypothalamus Connectivity in Chronic and Episodic Migraine · PMID 35295486 | Migraine | Ralentissement de la progression · Immunomodulation | Publication | PubMed | Voir la publication source Chronic migraine is a disabling neurological disorder that imposes a considerable burden on individual and socioeconomi… | Frontiers in pain research (Lausanne, Switzerland) 2026-07-22 21:21:25 | Source |
| The role and interaction of hypothalamic-related neurotransmitters in… HYPOTHAMIG — Hypothalamus Connectivity in Chronic and Episodic Migraine · PMID 40350428 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Migraine is a complex neurological disorder frequently associated with hypothalamic dysfunction. This brain region is e… | The journal of headache and pain 2026-07-22 21:21:25 | Source |
| Design of active pharmaceutical ingredient-ionic liquids for enhanced… Non-steroidal anti-inflammatory drug (NSAID) · PMID 42364699 | Migraine | Immunomodulation | Publication | PubMed | Voir la publication source Active pharmaceutical ingredient ionic liquids (API-ILs) can enhance skin delivery by tuning physicochemical properties… | Journal of controlled release : official journal of th… 2026-07-22 21:21:24 | Source |
| Incidence of Heterotopic Ossification Following Double-Incision Techn… Non-steroidal anti-inflammatory drug (NSAID) · PMID 42438580 | Migraine | Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Background Heterotopic ossification (HO) is a postoperative finding that may occur after distal biceps tendon repair us… | Cureus 2026-07-22 21:21:24 | Source |
| Comparison of propranolol LA 80 mg and propranolol LA 160 mg in migra… propranolol LA · PMID 8495455 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Thirty patients with severe classical and common migraine participated in a double-blind placebo-controlled cross-over… | Cephalalgia : an international journal of headache 2026-07-22 21:21:23 | Source |
| Randomized, placebo-controlled trial of propranolol added to topirama… propranolol LA · PMID 22377815 | Migraine | À vérifier | Publication | PubMed | Voir la publication source To assess the efficacy and safety of adding propranolol to topiramate in chronic migraine subjects inadequately control… | Neurology 2026-07-22 21:21:23 | Source |
| Adjunctive transcranial DC stimulation in the management of refractor… DC Stimulator (Transcranial Direct Current Stimulator) · PMID 42248710 | Migraine | Remyélinisation indirecte / réparation | Publication | PubMed | Voir la publication source Pathogenic POLG variants produce an age-related progressive multi-system mitochondrial disorder, with neurologic manife… | Seizure 2026-07-22 21:21:22 | Source |
| Reducing state anxiety with alpha-frequency transcranial alternating… DC Stimulator (Transcranial Direct Current Stimulator) · PMID 42208813 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source Anxiety reactivity to acute stress is a transdiagnostic vulnerability factor. We tested whether a single session of alp… | Journal of affective disorders 2026-07-22 21:21:22 | Source |
| Innovation is not enough: lessons from lasmiditan for real-world effe… Lasmiditan · PMID 42415704 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Résumé non disponible dans la base locale. | Expert review of neurotherapeutics 2026-07-22 21:21:20 | Source |
| Regulation of mitochondrial biogenesis by the 5-HT1F receptor and its… Lasmiditan · PMID 42457119 | Migraine | Remyélinisation indirecte / réparation · Traitement symptomatique · Thérapie gé… | Publication | PubMed | Voir la publication source Muscle spasticity is among the common secondary complications in patients with spinal cord injury (SCI). On the basis o… | Neuroscience letters 2026-07-22 21:21:20 | Source |
Exploration — prudence
Pistes exploratoires 5
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Bavisant BRAVEinMS — Bavisant | Migraine | Remyélinisation · Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Antagonisme du récepteur H3 de l’histamine Bavisant est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migra… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| Tol-MP Tol-MP — tolérance immunitaire spécifique de la myéline | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Microparticules biodégradables chargées en rapamycine et fonctionnalisées… Tol-MP est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migrain… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| SetPoint System SetPoint System — SetPoint Medical | Migraine | Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | re ApplicationsPublicationsCompanyCareersNewsGet startedGet startedNewsThe… SetPoint System est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation immunométabolique de la microglie 4-octyl itaconate et dérivés est étudié dans Sclérose latérale amyotrophique et documente plusieurs axes biologiques po… | Rapprochement Biomedical Watch · Sclérose latérale amy… | Détail |
| N-PPG N-PPG — modulation métabolique cérébrale | Migraine | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation métabolique et mitohormèse N-PPG est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être pertinents pour Migrai… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |