Vue transversale de la maladie
Migraine
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
Périmètre
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1236 résultats correspondants
· 45 visibles sur cette page
dans le périmètre Migraine
Niveau clinique
Études et traitements 570
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Caffeine (200 mg) NCT07022496 · Assessment of Oral Caffeine Intake in Changing the Severity of Acute Migraine At… | Migraine | À vérifier | Phase 4 | RECRUITING | Caffeine extracted from green tea to abort acute attack of Migraine À vérifier | ClinicalTrials.gov 2026-08-13 14:17:14 | Détail |
| HELP-VM — Healthy Living Partnerships for Veterans With Migraine NCT04373330 · NCT04373330 | Migraine | Traitement symptomatique | Non applicable | WITHDRAWN | This pilot study, modeled upon the successful and empirically validated HE… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:14 | Détail |
| Partial Rebreathing Device NCT05546385 · PAREMA1 — PArtial REbreathing for Migraine With Aura 1 | Migraine | À vérifier | Non applicable | TERMINATED | A prospective, multi-centre, randomized, double-blind, sham-controlled, pa… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:14 | Détail |
| Active drug for chronic migraine treatment. NCT07071506 · New Methods for Evaluating Preventive Migraine Treatment | Migraine | À vérifier | Non applicable | RECRUITING | The study aims to test interactions between drug and placebo-responses in… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Actual device PFO closure NCT04100135 · RELIEF — GORE® CARDIOFORM Septal Occluder Migraine Clinical Study | Migraine | À vérifier | Non applicable | TERMINATED | Multi-center, prospective, randomized, placebo- and sham-controlled study… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| ACU-BRAIN — Brain Connectome for Acupuncture-treated Migraine Patients NCT04157192 · NCT04157192 | Migraine | Traitement symptomatique | Non applicable | COMPLETED | Acupuncture has been a means of treating headaches and migraine since 2002… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| ACUPMIGRAINE — The Impact of Acupuncture on Biomarkers of Brain Injur… NCT07292506 · NCT07292506 | Migraine | Immunomodulation · Traitement symptomatique | Non applicable | ACTIVE_NOT_RECRUITING | Migraine is more than just a headache-it can involve changes in the brain… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Amiloride NCT04063540 · APAM — Acid-Sensing Ion Channel and Migraine Disease Proof of Concept Study on t… | Migraine | À vérifier | Phase 2 | RECRUITING | Recent data suggest involvement of Acid-Sensing Ion Channel channels in th… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| App-Based Migraine Treatment: The Health enSuite Study NCT06797076 · NCT06797076 | Migraine | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | Health enSuite is a suite of applications designed by our research team at… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Atogepant 60 mg NCT06414044 · STAR — Italian Real-life obServational Study on the effecTiveness, sAfety and To… | Migraine | À vérifier | À vérifier | ACTIVE_NOT_RECRUITING | This goal of this study is to compare three medications used for migraine… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| BE WELL With Migraine: Brain Education and WELLness With Migraine NCT05987592 · NCT05987592 | Migraine | À vérifier | Non applicable | RECRUITING | The goal of this randomized clinical trial is to evaluate two different no… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Biodegradable occluder NCT06203873 · BioMetal — A Comparison of Biodegradable and Metal Occluders in Patients With PF… | Migraine | Traitement symptomatique | Non applicable | RECRUITING | Migraine is one of the most common chronic neurological disorders, posing… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Calcitonin-gene related peptide (CGRP) NCT07021859 · Induction of Migraine Attacks With Aura Using Calcitonin Gene-Related Peptide | Migraine | À vérifier | Non applicable | RECRUITING | Calcitonin gene-related peptide (CGRP) is a key neuropeptide in migraine p… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Clorazepate Dipotassium NCT04726592 · CLORMIG — Efficacy of CLORazepate for the Treatment of MIGraine Attack in the Em… | Migraine | À vérifier | Phase 3 | TERMINATED | The purpose of this study is to evaluate the efficacy of clorazepate in ad… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Exploring the Effect of the Transcendental Meditation® Technique on M… NCT06695156 · NCT06695156 | Migraine | À vérifier | Non applicable | COMPLETED | This research will explore the effect of the Transcendental Meditation® Te… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Levcromakalim NCT04853797 · Effect of Ivabradine on Levcromakalim-Induced Symptoms in Individuals With Migra… | Migraine | Traitement symptomatique | Non applicable | COMPLETED | This study aims to explore the effect of Ivabradine on Levcromakalim-induc… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Mi-Helper NCT06874361 · CALM3 — Cooling to Alleviate Migraine #3 | Migraine | À vérifier | Non applicable | COMPLETED | This is a prospective, double-blind, sham-controlled, randomized, decentra… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| MTX101 NCT06728553 · Safety and Efficacy Trial of MTX101 2mg for the Acute Treatment of Migraine in A… | Migraine | Traitement symptomatique · Thérapie génique | Phase 2 | COMPLETED | The goal of this clinical trial is to learn if drug MTX101 works to treat… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Nerivio device NCT06023953 · Migraine With and Without Aura Characteristics and Response to Remote Electrical… | Migraine | Traitement symptomatique | À vérifier | COMPLETED | This is a Post-marketing, real-world evidence study investigating the safe… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
| Neuromodulation Wearable Device NCT07642414 · A Comprehensive Digital Care Program for Migraine Management | Migraine | À vérifier | Non applicable | RECRUITING | This study evaluates the clinical effectiveness of the Enso for Migraine p… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:13 | Détail |
Découverte scientifique
Recherches et trouvailles 0
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune trouvaille ne correspond aux filtres. | |||||||
Bibliographie
Publications 661
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Amylin Coexisting With Peptide YY (PYY) and Amylin/PYY Cells Correspo… Amylin · PMID 42559671 | Migraine | Immunomodulation | Publication | PubMed | Voir la publication source The distribution of amylin-like substances was investigated by immunohistochemistry in the pancreas of the Japanese eel… | Anatomia, histologia, embryologia 2026-08-08 00:58:52 | Source |
| Acute effects of "exercise snacks" on postprandial glucose and insuli… Endothelin-1 · PMID 42558375 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source Exercise snacks-short, frequent bouts of physical activity that interrupt prolonged sitting-improve postprandial glucos… | Frontiers in endocrinology 2026-08-08 00:58:51 | Source |
| Hypoxemia with atelectasis during clazosentan therapy after subarachn… Endothelin-1 · PMID 42558750 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Clazosentan, a selective endothelin-A (ET-A) receptor antagonist, is used to prevent cerebral vasospasm after aneurysma… | Nagoya journal of medical science 2026-08-08 00:58:51 | Source |
| Emerging Neurovascular Interventions for the Prevention of Cerebral V… Cilostazol · PMID 42540693 | Migraine | Neuroprotection · Immunomodulation | Publication | PubMed | Voir la publication source Aneurysmal subarachnoid hemorrhage remains a major cause of neurological morbidity and mortality, with delayed cerebral… | Cureus 2026-08-08 00:58:50 | Source |
| Isosorbide Mononitrate/Cilostazol for Lacunar Cerebral Small Vessel D… Cilostazol · PMID 42535538 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Lacunar stroke can cause cognitive decline and dependency. The LACI-2 (Lacunar Intervention Trial-2) trial showed that… | Journal of the American Heart Association 2026-08-08 00:58:50 | Source |
| Twelve-months prospective real-world assessment of effectiveness and… Eptinezumab 100 mg or Eptinezumab 300 mg administered intravenously in 100 mL saline solution… | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Randomized clinical trials have demonstrated the efficacy and safety of eptinezumab. The aim of this study was to evalu… | The journal of headache and pain 2026-08-08 00:58:47 | Source |
| Targeting G-coupled GPCRs to inhibit nociceptors: Insights from the s… Triptan · PMID 42532046 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Pain perception is initiated upon activation of nociceptors of the dorsal root ganglia (DRG) and trigeminal ganglia. We… | Cell reports. Medicine 2026-08-08 00:58:45 | Source |
| Gastrointestinal Ascariasis: Unusual Presentation in 2 Cases. Non-steroidal anti-inflammatory drug (NSAID) · PMID 42540124 | Migraine | Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Ascariasis is a helminthic infection caused by the nematode and remains the most prevalent helminth infection worldwide… | Nigerian medical journal : journal of the Nigeria Medi… 2026-08-08 00:58:44 | Source |
| Impact of semaglutide introduction on the use of triptans: an interru… Triptan · PMID 42557547 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Emerging evidence suggests that glucagon-like peptide-1 receptor agonist (GLP-1RA) may be associated with reduced migra… | The journal of headache and pain 2026-08-08 00:58:44 | Source |
| In Vitro Evaluation of Lornoxicam Liquitablets: Permeability, Anti-In… Non-steroidal anti-inflammatory drug (NSAID) · PMID 42546887 | Migraine | Immunomodulation · Thérapie génique | Publication | PubMed | Voir la publication source Lornoxicam (LXM) is a potent non-steroidal anti-inflammatory drug (NSAID), characterised by low aqueous solubility, whi… | European journal of pharmaceutical sciences : official… 2026-08-08 00:58:44 | Source |
| Botulinum toxin in peripheral facial paralysis: systematic review and… Onabotulinum toxin A · PMID 42517166 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Peripheral facial paralysis (PFP) causes both static and dynamic facial dysfunctions, leading to synkinesis, hypertonia… | European journal of physical and rehabilitation medici… 2026-08-08 00:58:43 | Source |
| Repeated botulinum toxin injections for neurogenic thoracic outlet sy… Onabotulinum toxin A · PMID 42550976 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Neurogenic thoracic outlet syndrome (nTOS) is a condition caused by compression of the brachial plexus in the thoracic… | Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = T… 2026-08-08 00:58:43 | Source |
| Projected budget impact of pharmacotherapy scenarios for obesity and… topiramate · PMID 42565180 | Migraine | À vérifier | Publication | PubMed | Voir la publication source The increasing prevalence of obesity is generating demand for chronic pharmacologic treatment, but Latin American evide… | Obesity pillars 2026-08-08 00:58:42 | Source |
| Weight mitigation and tolerability of adjunctive topiramate in acute… topiramate · PMID 42558898 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Psychotropic medications are often associated with significant and rapid weight gain in pediatric populations, especial… | Frontiers in psychiatry 2026-08-08 00:58:42 | Source |
| Feasibility of Emotional Awareness and Expression Therapy Adapted for… Exploring Clinical Trial Experiences of Patients With Migraine · PMID 41742651 | Migraine | Ralentissement de la progression | Publication | PubMed | Voir la publication source Chronic headache, including migraine, is often associated with psychiatric conditions and adverse childhood experiences… | The Canadian journal of neurological sciences. Le jour… 2026-08-08 00:58:38 | Source |
| Physical Therapy Targeting Autonomic and Dura Mater Function: SPINEPA… Exploring Clinical Trial Experiences of Patients With Migraine · PMID 41324433 | Migraine | Ralentissement de la progression · Traitement symptomatique | Publication | PubMed | Voir la publication source Persistent post-traumatic headache (PPTH) or concussion is a significant United States military problem, and pharmacolo… | Physical therapy 2026-08-08 00:58:38 | Source |
| Efficacy and safety of gepants in migraine management: a narrative re… Rimegepant 75 MG · PMID 42548099 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Gepants, oral antagonists of the calcitonin gene-related peptide (CGRP) receptor, represent a new therapeutic class in… | Journal of oral & facial pain and headache 2026-08-08 00:58:35 | Source |
| Diagnostic value of shear wave elastography in assessing the effectiv… Botulinum toxin type A · PMID 42566101 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source Complex W3 ventral hernias with loss of domain (LOD) pose challenges in abdominal wall reconstruction due to pathologic… | Hernia : the journal of hernias and abdominal wall sur… 2026-08-08 00:58:34 | Source |
| [Treatment persistence and adherence with botulinum toxin type A and… Botulinum toxin type A · PMID 42565401 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source To compare the treatment persistence and adherence with botulinum toxin type A (Relatox; BTA) and monoclonal antibodies… | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 2026-08-08 00:58:34 | Source |
| Multi-organ AI endophenotypes chart the heterogeneity of brain, eye a… Digoxin · PMID 42559122 | Migraine | Ralentissement de la progression · Thérapie génique | Publication | PubMed | Voir la publication source Disease heterogeneity and commonality pose significant challenges to precision medicine, as traditional approaches freq… | Nature. Mental health 2026-08-08 00:57:54 | Source |
Exploration — prudence
Pistes exploratoires 5
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Bavisant BRAVEinMS — Bavisant | Migraine | Remyélinisation · Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Antagonisme du récepteur H3 de l’histamine Bavisant est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migra… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| Tol-MP Tol-MP — tolérance immunitaire spécifique de la myéline | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Microparticules biodégradables chargées en rapamycine et fonctionnalisées… Tol-MP est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migrain… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| SetPoint System SetPoint System — SetPoint Medical | Migraine | Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | re ApplicationsPublicationsCompanyCareersNewsGet startedGet startedNewsThe… SetPoint System est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation immunométabolique de la microglie 4-octyl itaconate et dérivés est étudié dans Sclérose latérale amyotrophique et documente plusieurs axes biologiques po… | Rapprochement Biomedical Watch · Sclérose latérale amy… | Détail |
| N-PPG N-PPG — modulation métabolique cérébrale | Migraine | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation métabolique et mitohormèse N-PPG est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être pertinents pour Migrai… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |