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Migraine
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
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1236 résultats correspondants
· 45 visibles sur cette page
dans le périmètre Migraine
Niveau clinique
Études et traitements 570
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Prodigy internal pulse generator occipital nerve stimulator NCT07087678 · Occipital Nerve Stimulation in Chronic Migraine | Migraine | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | The goal of this clinical trial is to compare two different types of occip… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| Propofol NCT02492295 · Low-dose Propofol for the Treatment of Severe Refractory Migraine Headache in th… | Migraine | Immunomodulation · Traitement symptomatique | Non applicable | TERMINATED | Migraine headache is a frequent Emergency Department complaint. While firs… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| Psychological and Biological Markers of Refractory Migraine NCT05046119 · NCT05046119 | Migraine | Traitement symptomatique | À vérifier | UNKNOWN | The term "refractory" migraine describes a particularly aggressive form of… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| pulsed electromagnetic field NCT01670214 · Pulsed Electromagnetic Field Therapy in the Refractory Migraine | Migraine | À vérifier | Non applicable | COMPLETED | Pulsed electromagnetic field (PEMF) as prophylactic treatment may prevent… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| SCS NCT05382832 · BTX/SCS/TMig — Botox Vs Spinal Cord Stimulation in the Treatment of Refractory M… | Migraine | À vérifier | Non applicable | UNKNOWN | The clinical trial is focused on the treatment of selected patients with a… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| Senza™, High Frequency Spinal Cord Stimulator for Refractory Chronic… NCT01653340 · rCM HF-SCS — A Feasibility Clinical Trial to Evaluate High Frequency Spinal Cord… | Migraine | À vérifier | Non applicable | COMPLETED | The purpose of this study is to assess short- and long-term safety, tolera… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| The Use of Autologous Mesenchymal Stem Cell Preparation for Treatment… NCT04064879 · NCT04064879 | Migraine | Traitement symptomatique · Thérapie cellulaire | Non applicable | SUSPENDED | The present study is being undertaken as a phase I study to determine the… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| Transcranial electrical stimulation NCT05099406 · Home-based Transcranial Stimulation in the Treatment of Patients With Refractory… | Migraine | Traitement symptomatique · Thérapie génique | Non applicable | UNKNOWN | Refractory chronic pain represents a serious and limiting health condition… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| Cadwell Cascade 32 PRO NCT07402954 · MMA-Stim — Stimulation of External Carotid Artery Circulation | Migraine | Traitement symptomatique · Thérapie génique | Non applicable | RECRUITING | This study is testing a new approach to help people with migraine headache… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:16 | Détail |
| embolization of middle meningeal arteries NCT07223008 · MMAE-Migraine — Bilateral Embolization of the Middle Meningeal Arteries for Refr… | Migraine | À vérifier | Non applicable | RECRUITING | This study is to test the safety and feasibility of a procedure called emb… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:16 | Détail |
| Pulsed Radiofrequency of the Sphenopalatine Ganglion NCT07370142 · SPG-PRF — Sphenopalatine Ganglion Pulsed Radiofrequency Treatment Outcomes | Migraine | Traitement symptomatique | Non applicable | COMPLETED | Purpose of the Study: This study aims to evaluate the clinical effectivene… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:16 | Détail |
| Amylin NCT07340788 · Amylin-Induced Migraine Attacks Without Aura | Migraine | À vérifier | Non applicable | NOT_YET_RECRUITING | Pramlintide is a peptide analogue of human amylin which is a vasoactive si… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:15 | Détail |
| Discussion on the Mechanism of Acupuncture on Patients with Paroxysma… NCT06676670 · NCT06676670 | Migraine | Thérapie génique | Non applicable | UNKNOWN | Background: Migraine is common but poorly managed with drugs. Acupuncture,… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:15 | Détail |
| FAST — Molecular Phenotyping of Migraine Patients According to Sex an… NCT06674772 · NCT06674772 | Migraine | À vérifier | À vérifier | RECRUITING | Patients will be asked to visit the study center 2 times, the first time f… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:15 | Détail |
| Fu's Subcutaneous Needling NCT07068815 · Efficacy and Mechanism of Fu's Subcutaneous Needling Treatment for Migraine With… | Migraine | Traitement symptomatique | Phase 1 | NOT_YET_RECRUITING | This study aimed to compare the analgesic efficacy and quality-of-life imp… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:15 | Détail |
| Levcromakalim NCT05211050 · SLIM — Effect of Sumatriptan on Levcromakalim-Induced Symptoms in Individuals Wi… | Migraine | Traitement symptomatique | Non applicable | COMPLETED | This study aims to explore the effect of Ivabradine on Levcromakalim-induc… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:15 | Détail |
| Myotensive Extraocular Muscle Techniques Added to Manual Therapy for… NCT07254598 · NCT07254598 | Migraine | Ralentissement de la progression · Traitement symptomatique · Thérapie génique | Non applicable | NOT_YET_RECRUITING | Migraine without aura is a highly prevalent and disabling primary headache… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:15 | Détail |
| Substance P NCT06959004 · Substance P-Induced Migraine Attacks Without Aura | Migraine | À vérifier | Non applicable | RECRUITING | Substance P is a neuropeptide implicated in the pathogenesis of headache.… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:15 | Détail |
| Almotriptan 12.5 Mg Oral Tablet NCT05214001 · ATOM — Evaluation of the Efficacy of Almotriptan and Ubrogepant for the Acute Tr… | Migraine | Traitement symptomatique | Phase 4 | TERMINATED | In a real-world population of adults with migraine, the investigators woul… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:14 | Détail |
| Be-Home-Kids — Feasibility and Effectiveness of Home-behavioral Progr… NCT04604977 · NCT04604977 | Migraine | Traitement symptomatique | Non applicable | COMPLETED | Chronic Migraine and Migraine without aura at high frequency are disabling… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:14 | Détail |
Découverte scientifique
Recherches et trouvailles 0
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune trouvaille ne correspond aux filtres. | |||||||
Bibliographie
Publications 661
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Stephanoside B modulates metabolic gene expression and lengthens the… dexamethasone · PMID 42484698 | Migraine | Immunomodulation | Publication | PubMed | Voir la publication source Gymnema (G.) inodorum is a medicinal plant with anti-diabetic, anti-obesity, and anti-inflammatory properties tradition… | Molecular biology reports 2026-07-22 21:21:52 | Source |
| Peripheral nerve stimulation registry for intractable migraine headac… Relief — Peripheral Nerve Stimulation Registry for Intractable Migraine Headache · PMID 323779… | Migraine | Ralentissement de la progression | Publication | PubMed | Voir la publication source Migraine is common and ranked as the first cause of disability in people under fifty. Despite significant advances in i… | Acta neurochirurgica 2026-07-22 21:21:32 | Source |
| Comparison of Balanced General Anesthesia Protocols in Sleeve Gastrec… ketamine infusion · PMID 42455083 | Migraine | À vérifier | Publication | PubMed | Voir la publication source To evaluate the effects of two different anesthesia management techniques applied to sleeve gastrectomy patients on pos… | Journal of perianesthesia nursing : official journal o… 2026-07-22 21:21:31 | Source |
| Innovative integration of high dose ketamine infusion, psychological… ketamine infusion · PMID 42454590 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Ketamine is a noncompetitive antagonist of the N-methyl-D-aspartate receptor that has garnered significant interest as… | Pain management 2026-07-22 21:21:31 | Source |
| Atorvastatin Reduces Alcohol-Related Cardiac and Liver Tissue Damage,… Endothelin-1 · PMID 42478929 | Migraine | Remyélinisation indirecte / réparation · Neuroprotection · Immunomodulation | Publication | PubMed | Voir la publication source Excessive alcohol consumption causes significant cardio-hepatic damage. This study investigated the effects of standard… | Journal of biochemical and molecular toxicology 2026-07-22 21:21:29 | Source |
| Involvement of Mitophagy in Endothelin-1 Mediated Neurodegeneration i… Endothelin-1 · PMID 42465463 | Migraine | Remyélinisation indirecte / réparation | Publication | PubMed | Voir la publication source The ultimate cause of blindness in glaucoma is the death of retinal ganglion cells, and understanding the mechanism beh… | bioRxiv : the preprint server for biology 2026-07-22 21:21:29 | Source |
| Connexin 43 subcellular localization: From trafficking dynamics to pa… Tonabersat · PMID 42069098 | Migraine | Remyélinisation indirecte / réparation · Immunomodulation | Publication | PubMed | Voir la publication source Connexin 43 (Cx43) exhibits remarkable functional diversity that is precisely dictated by its dynamic subcellular local… | Cellular signalling 2026-07-22 21:21:28 | Source |
| Oral Tonabersat Connexin-43 Modulator for Diabetic Macular Edema with… Tonabersat · PMID 42064012 | Migraine | Immunomodulation | Publication | PubMed | Voir la publication source Evaluate oral tonabersat, a connexin-43 hemichannel modulator, on central subfield thickness (CST) in eyes with center-… | Ophthalmology science 2026-07-22 21:21:28 | Source |
| Cross-response to Calcitonin Gene-Related Peptide monoclonal antibodi… Eptinezumab 100 mg or Eptinezumab 300 mg administered intravenously in 100 mL saline solution… | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Real-world data on calcitonin gene-related peptide (CGRP) monoclonal antibodies (mAbs) are essential to determine wheth… | The journal of headache and pain 2026-07-22 21:21:27 | Source |
| Long-term treatment with Eptinezumab in special treatment situations:… Eptinezumab 100 mg or Eptinezumab 300 mg administered intravenously in 100 mL saline solution… | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source The neurotransmitter Calcitonin Gene related Peptide (CGRP) is one of the key players driving migraine attacks. Randomi… | Journal of the neurological sciences 2026-07-22 21:21:27 | Source |
| Chronic Migraine Pathophysiology and Treatment: A Review of Current P… HYPOTHAMIG — Hypothalamus Connectivity in Chronic and Episodic Migraine · PMID 35295486 | Migraine | Ralentissement de la progression · Immunomodulation | Publication | PubMed | Voir la publication source Chronic migraine is a disabling neurological disorder that imposes a considerable burden on individual and socioeconomi… | Frontiers in pain research (Lausanne, Switzerland) 2026-07-22 21:21:25 | Source |
| The role and interaction of hypothalamic-related neurotransmitters in… HYPOTHAMIG — Hypothalamus Connectivity in Chronic and Episodic Migraine · PMID 40350428 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Migraine is a complex neurological disorder frequently associated with hypothalamic dysfunction. This brain region is e… | The journal of headache and pain 2026-07-22 21:21:25 | Source |
| Design of active pharmaceutical ingredient-ionic liquids for enhanced… Non-steroidal anti-inflammatory drug (NSAID) · PMID 42364699 | Migraine | Immunomodulation | Publication | PubMed | Voir la publication source Active pharmaceutical ingredient ionic liquids (API-ILs) can enhance skin delivery by tuning physicochemical properties… | Journal of controlled release : official journal of th… 2026-07-22 21:21:24 | Source |
| Incidence of Heterotopic Ossification Following Double-Incision Techn… Non-steroidal anti-inflammatory drug (NSAID) · PMID 42438580 | Migraine | Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Background Heterotopic ossification (HO) is a postoperative finding that may occur after distal biceps tendon repair us… | Cureus 2026-07-22 21:21:24 | Source |
| Comparison of propranolol LA 80 mg and propranolol LA 160 mg in migra… propranolol LA · PMID 8495455 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Thirty patients with severe classical and common migraine participated in a double-blind placebo-controlled cross-over… | Cephalalgia : an international journal of headache 2026-07-22 21:21:23 | Source |
| Randomized, placebo-controlled trial of propranolol added to topirama… propranolol LA · PMID 22377815 | Migraine | À vérifier | Publication | PubMed | Voir la publication source To assess the efficacy and safety of adding propranolol to topiramate in chronic migraine subjects inadequately control… | Neurology 2026-07-22 21:21:23 | Source |
| Adjunctive transcranial DC stimulation in the management of refractor… DC Stimulator (Transcranial Direct Current Stimulator) · PMID 42248710 | Migraine | Remyélinisation indirecte / réparation | Publication | PubMed | Voir la publication source Pathogenic POLG variants produce an age-related progressive multi-system mitochondrial disorder, with neurologic manife… | Seizure 2026-07-22 21:21:22 | Source |
| Reducing state anxiety with alpha-frequency transcranial alternating… DC Stimulator (Transcranial Direct Current Stimulator) · PMID 42208813 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source Anxiety reactivity to acute stress is a transdiagnostic vulnerability factor. We tested whether a single session of alp… | Journal of affective disorders 2026-07-22 21:21:22 | Source |
| Innovation is not enough: lessons from lasmiditan for real-world effe… Lasmiditan · PMID 42415704 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Résumé non disponible dans la base locale. | Expert review of neurotherapeutics 2026-07-22 21:21:20 | Source |
| Regulation of mitochondrial biogenesis by the 5-HT1F receptor and its… Lasmiditan · PMID 42457119 | Migraine | Remyélinisation indirecte / réparation · Traitement symptomatique · Thérapie gé… | Publication | PubMed | Voir la publication source Muscle spasticity is among the common secondary complications in patients with spinal cord injury (SCI). On the basis o… | Neuroscience letters 2026-07-22 21:21:20 | Source |
Exploration — prudence
Pistes exploratoires 5
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Bavisant BRAVEinMS — Bavisant | Migraine | Remyélinisation · Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Antagonisme du récepteur H3 de l’histamine Bavisant est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migra… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| Tol-MP Tol-MP — tolérance immunitaire spécifique de la myéline | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Microparticules biodégradables chargées en rapamycine et fonctionnalisées… Tol-MP est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migrain… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| SetPoint System SetPoint System — SetPoint Medical | Migraine | Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | re ApplicationsPublicationsCompanyCareersNewsGet startedGet startedNewsThe… SetPoint System est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation immunométabolique de la microglie 4-octyl itaconate et dérivés est étudié dans Sclérose latérale amyotrophique et documente plusieurs axes biologiques po… | Rapprochement Biomedical Watch · Sclérose latérale amy… | Détail |
| N-PPG N-PPG — modulation métabolique cérébrale | Migraine | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation métabolique et mitohormèse N-PPG est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être pertinents pour Migrai… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |