Vue transversale de la maladie
Migraine
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
Périmètre
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1236 résultats correspondants
· 45 visibles sur cette page
dans le périmètre Migraine
Niveau clinique
Études et traitements 570
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Prodigy internal pulse generator occipital nerve stimulator NCT07087678 · Occipital Nerve Stimulation in Chronic Migraine | Migraine | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | The goal of this clinical trial is to compare two different types of occip… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| Propofol NCT02492295 · Low-dose Propofol for the Treatment of Severe Refractory Migraine Headache in th… | Migraine | Immunomodulation · Traitement symptomatique | Non applicable | TERMINATED | Migraine headache is a frequent Emergency Department complaint. While firs… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| Psychological and Biological Markers of Refractory Migraine NCT05046119 · NCT05046119 | Migraine | Traitement symptomatique | À vérifier | UNKNOWN | The term "refractory" migraine describes a particularly aggressive form of… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| pulsed electromagnetic field NCT01670214 · Pulsed Electromagnetic Field Therapy in the Refractory Migraine | Migraine | À vérifier | Non applicable | COMPLETED | Pulsed electromagnetic field (PEMF) as prophylactic treatment may prevent… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| SCS NCT05382832 · BTX/SCS/TMig — Botox Vs Spinal Cord Stimulation in the Treatment of Refractory M… | Migraine | À vérifier | Non applicable | UNKNOWN | The clinical trial is focused on the treatment of selected patients with a… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| Senza™, High Frequency Spinal Cord Stimulator for Refractory Chronic… NCT01653340 · rCM HF-SCS — A Feasibility Clinical Trial to Evaluate High Frequency Spinal Cord… | Migraine | À vérifier | Non applicable | COMPLETED | The purpose of this study is to assess short- and long-term safety, tolera… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| The Use of Autologous Mesenchymal Stem Cell Preparation for Treatment… NCT04064879 · NCT04064879 | Migraine | Traitement symptomatique · Thérapie cellulaire | Non applicable | SUSPENDED | The present study is being undertaken as a phase I study to determine the… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| Transcranial electrical stimulation NCT05099406 · Home-based Transcranial Stimulation in the Treatment of Patients With Refractory… | Migraine | Traitement symptomatique · Thérapie génique | Non applicable | UNKNOWN | Refractory chronic pain represents a serious and limiting health condition… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| Cadwell Cascade 32 PRO NCT07402954 · MMA-Stim — Stimulation of External Carotid Artery Circulation | Migraine | Traitement symptomatique · Thérapie génique | Non applicable | RECRUITING | This study is testing a new approach to help people with migraine headache… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:16 | Détail |
| embolization of middle meningeal arteries NCT07223008 · MMAE-Migraine — Bilateral Embolization of the Middle Meningeal Arteries for Refr… | Migraine | À vérifier | Non applicable | RECRUITING | This study is to test the safety and feasibility of a procedure called emb… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:16 | Détail |
| Pulsed Radiofrequency of the Sphenopalatine Ganglion NCT07370142 · SPG-PRF — Sphenopalatine Ganglion Pulsed Radiofrequency Treatment Outcomes | Migraine | Traitement symptomatique | Non applicable | COMPLETED | Purpose of the Study: This study aims to evaluate the clinical effectivene… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:16 | Détail |
| Amylin NCT07340788 · Amylin-Induced Migraine Attacks Without Aura | Migraine | À vérifier | Non applicable | NOT_YET_RECRUITING | Pramlintide is a peptide analogue of human amylin which is a vasoactive si… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:15 | Détail |
| Discussion on the Mechanism of Acupuncture on Patients with Paroxysma… NCT06676670 · NCT06676670 | Migraine | Thérapie génique | Non applicable | UNKNOWN | Background: Migraine is common but poorly managed with drugs. Acupuncture,… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:15 | Détail |
| FAST — Molecular Phenotyping of Migraine Patients According to Sex an… NCT06674772 · NCT06674772 | Migraine | À vérifier | À vérifier | RECRUITING | Patients will be asked to visit the study center 2 times, the first time f… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:15 | Détail |
| Fu's Subcutaneous Needling NCT07068815 · Efficacy and Mechanism of Fu's Subcutaneous Needling Treatment for Migraine With… | Migraine | Traitement symptomatique | Phase 1 | NOT_YET_RECRUITING | This study aimed to compare the analgesic efficacy and quality-of-life imp… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:15 | Détail |
| Levcromakalim NCT05211050 · SLIM — Effect of Sumatriptan on Levcromakalim-Induced Symptoms in Individuals Wi… | Migraine | Traitement symptomatique | Non applicable | COMPLETED | This study aims to explore the effect of Ivabradine on Levcromakalim-induc… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:15 | Détail |
| Myotensive Extraocular Muscle Techniques Added to Manual Therapy for… NCT07254598 · NCT07254598 | Migraine | Ralentissement de la progression · Traitement symptomatique · Thérapie génique | Non applicable | NOT_YET_RECRUITING | Migraine without aura is a highly prevalent and disabling primary headache… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:15 | Détail |
| Substance P NCT06959004 · Substance P-Induced Migraine Attacks Without Aura | Migraine | À vérifier | Non applicable | RECRUITING | Substance P is a neuropeptide implicated in the pathogenesis of headache.… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:15 | Détail |
| Almotriptan 12.5 Mg Oral Tablet NCT05214001 · ATOM — Evaluation of the Efficacy of Almotriptan and Ubrogepant for the Acute Tr… | Migraine | Traitement symptomatique | Phase 4 | TERMINATED | In a real-world population of adults with migraine, the investigators woul… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:14 | Détail |
| Be-Home-Kids — Feasibility and Effectiveness of Home-behavioral Progr… NCT04604977 · NCT04604977 | Migraine | Traitement symptomatique | Non applicable | COMPLETED | Chronic Migraine and Migraine without aura at high frequency are disabling… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:14 | Détail |
Découverte scientifique
Recherches et trouvailles 0
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune trouvaille ne correspond aux filtres. | |||||||
Bibliographie
Publications 661
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Amylin Coexisting With Peptide YY (PYY) and Amylin/PYY Cells Correspo… Amylin · PMID 42559671 | Migraine | Immunomodulation | Publication | PubMed | Voir la publication source The distribution of amylin-like substances was investigated by immunohistochemistry in the pancreas of the Japanese eel… | Anatomia, histologia, embryologia 2026-08-08 00:58:52 | Source |
| Acute effects of "exercise snacks" on postprandial glucose and insuli… Endothelin-1 · PMID 42558375 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source Exercise snacks-short, frequent bouts of physical activity that interrupt prolonged sitting-improve postprandial glucos… | Frontiers in endocrinology 2026-08-08 00:58:51 | Source |
| Hypoxemia with atelectasis during clazosentan therapy after subarachn… Endothelin-1 · PMID 42558750 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Clazosentan, a selective endothelin-A (ET-A) receptor antagonist, is used to prevent cerebral vasospasm after aneurysma… | Nagoya journal of medical science 2026-08-08 00:58:51 | Source |
| Emerging Neurovascular Interventions for the Prevention of Cerebral V… Cilostazol · PMID 42540693 | Migraine | Neuroprotection · Immunomodulation | Publication | PubMed | Voir la publication source Aneurysmal subarachnoid hemorrhage remains a major cause of neurological morbidity and mortality, with delayed cerebral… | Cureus 2026-08-08 00:58:50 | Source |
| Isosorbide Mononitrate/Cilostazol for Lacunar Cerebral Small Vessel D… Cilostazol · PMID 42535538 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Lacunar stroke can cause cognitive decline and dependency. The LACI-2 (Lacunar Intervention Trial-2) trial showed that… | Journal of the American Heart Association 2026-08-08 00:58:50 | Source |
| Twelve-months prospective real-world assessment of effectiveness and… Eptinezumab 100 mg or Eptinezumab 300 mg administered intravenously in 100 mL saline solution… | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Randomized clinical trials have demonstrated the efficacy and safety of eptinezumab. The aim of this study was to evalu… | The journal of headache and pain 2026-08-08 00:58:47 | Source |
| Targeting G-coupled GPCRs to inhibit nociceptors: Insights from the s… Triptan · PMID 42532046 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Pain perception is initiated upon activation of nociceptors of the dorsal root ganglia (DRG) and trigeminal ganglia. We… | Cell reports. Medicine 2026-08-08 00:58:45 | Source |
| Gastrointestinal Ascariasis: Unusual Presentation in 2 Cases. Non-steroidal anti-inflammatory drug (NSAID) · PMID 42540124 | Migraine | Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Ascariasis is a helminthic infection caused by the nematode and remains the most prevalent helminth infection worldwide… | Nigerian medical journal : journal of the Nigeria Medi… 2026-08-08 00:58:44 | Source |
| Impact of semaglutide introduction on the use of triptans: an interru… Triptan · PMID 42557547 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Emerging evidence suggests that glucagon-like peptide-1 receptor agonist (GLP-1RA) may be associated with reduced migra… | The journal of headache and pain 2026-08-08 00:58:44 | Source |
| In Vitro Evaluation of Lornoxicam Liquitablets: Permeability, Anti-In… Non-steroidal anti-inflammatory drug (NSAID) · PMID 42546887 | Migraine | Immunomodulation · Thérapie génique | Publication | PubMed | Voir la publication source Lornoxicam (LXM) is a potent non-steroidal anti-inflammatory drug (NSAID), characterised by low aqueous solubility, whi… | European journal of pharmaceutical sciences : official… 2026-08-08 00:58:44 | Source |
| Botulinum toxin in peripheral facial paralysis: systematic review and… Onabotulinum toxin A · PMID 42517166 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Peripheral facial paralysis (PFP) causes both static and dynamic facial dysfunctions, leading to synkinesis, hypertonia… | European journal of physical and rehabilitation medici… 2026-08-08 00:58:43 | Source |
| Repeated botulinum toxin injections for neurogenic thoracic outlet sy… Onabotulinum toxin A · PMID 42550976 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Neurogenic thoracic outlet syndrome (nTOS) is a condition caused by compression of the brachial plexus in the thoracic… | Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = T… 2026-08-08 00:58:43 | Source |
| Projected budget impact of pharmacotherapy scenarios for obesity and… topiramate · PMID 42565180 | Migraine | À vérifier | Publication | PubMed | Voir la publication source The increasing prevalence of obesity is generating demand for chronic pharmacologic treatment, but Latin American evide… | Obesity pillars 2026-08-08 00:58:42 | Source |
| Weight mitigation and tolerability of adjunctive topiramate in acute… topiramate · PMID 42558898 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Psychotropic medications are often associated with significant and rapid weight gain in pediatric populations, especial… | Frontiers in psychiatry 2026-08-08 00:58:42 | Source |
| Feasibility of Emotional Awareness and Expression Therapy Adapted for… Exploring Clinical Trial Experiences of Patients With Migraine · PMID 41742651 | Migraine | Ralentissement de la progression | Publication | PubMed | Voir la publication source Chronic headache, including migraine, is often associated with psychiatric conditions and adverse childhood experiences… | The Canadian journal of neurological sciences. Le jour… 2026-08-08 00:58:38 | Source |
| Physical Therapy Targeting Autonomic and Dura Mater Function: SPINEPA… Exploring Clinical Trial Experiences of Patients With Migraine · PMID 41324433 | Migraine | Ralentissement de la progression · Traitement symptomatique | Publication | PubMed | Voir la publication source Persistent post-traumatic headache (PPTH) or concussion is a significant United States military problem, and pharmacolo… | Physical therapy 2026-08-08 00:58:38 | Source |
| Efficacy and safety of gepants in migraine management: a narrative re… Rimegepant 75 MG · PMID 42548099 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Gepants, oral antagonists of the calcitonin gene-related peptide (CGRP) receptor, represent a new therapeutic class in… | Journal of oral & facial pain and headache 2026-08-08 00:58:35 | Source |
| Diagnostic value of shear wave elastography in assessing the effectiv… Botulinum toxin type A · PMID 42566101 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source Complex W3 ventral hernias with loss of domain (LOD) pose challenges in abdominal wall reconstruction due to pathologic… | Hernia : the journal of hernias and abdominal wall sur… 2026-08-08 00:58:34 | Source |
| [Treatment persistence and adherence with botulinum toxin type A and… Botulinum toxin type A · PMID 42565401 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source To compare the treatment persistence and adherence with botulinum toxin type A (Relatox; BTA) and monoclonal antibodies… | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 2026-08-08 00:58:34 | Source |
| Multi-organ AI endophenotypes chart the heterogeneity of brain, eye a… Digoxin · PMID 42559122 | Migraine | Ralentissement de la progression · Thérapie génique | Publication | PubMed | Voir la publication source Disease heterogeneity and commonality pose significant challenges to precision medicine, as traditional approaches freq… | Nature. Mental health 2026-08-08 00:57:54 | Source |
Exploration — prudence
Pistes exploratoires 5
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Bavisant BRAVEinMS — Bavisant | Migraine | Remyélinisation · Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Antagonisme du récepteur H3 de l’histamine Bavisant est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migra… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| Tol-MP Tol-MP — tolérance immunitaire spécifique de la myéline | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Microparticules biodégradables chargées en rapamycine et fonctionnalisées… Tol-MP est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migrain… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| SetPoint System SetPoint System — SetPoint Medical | Migraine | Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | re ApplicationsPublicationsCompanyCareersNewsGet startedGet startedNewsThe… SetPoint System est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation immunométabolique de la microglie 4-octyl itaconate et dérivés est étudié dans Sclérose latérale amyotrophique et documente plusieurs axes biologiques po… | Rapprochement Biomedical Watch · Sclérose latérale amy… | Détail |
| N-PPG N-PPG — modulation métabolique cérébrale | Migraine | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation métabolique et mitohormèse N-PPG est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être pertinents pour Migrai… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |