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Migraine
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
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1236 résultats correspondants
· 45 visibles sur cette page
dans le périmètre Migraine
Niveau clinique
Études et traitements 570
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Prodigy internal pulse generator occipital nerve stimulator NCT07087678 · Occipital Nerve Stimulation in Chronic Migraine | Migraine | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | The goal of this clinical trial is to compare two different types of occip… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| Propofol NCT02492295 · Low-dose Propofol for the Treatment of Severe Refractory Migraine Headache in th… | Migraine | Immunomodulation · Traitement symptomatique | Non applicable | TERMINATED | Migraine headache is a frequent Emergency Department complaint. While firs… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| Psychological and Biological Markers of Refractory Migraine NCT05046119 · NCT05046119 | Migraine | Traitement symptomatique | À vérifier | UNKNOWN | The term "refractory" migraine describes a particularly aggressive form of… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| pulsed electromagnetic field NCT01670214 · Pulsed Electromagnetic Field Therapy in the Refractory Migraine | Migraine | À vérifier | Non applicable | COMPLETED | Pulsed electromagnetic field (PEMF) as prophylactic treatment may prevent… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| SCS NCT05382832 · BTX/SCS/TMig — Botox Vs Spinal Cord Stimulation in the Treatment of Refractory M… | Migraine | À vérifier | Non applicable | UNKNOWN | The clinical trial is focused on the treatment of selected patients with a… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| Senza™, High Frequency Spinal Cord Stimulator for Refractory Chronic… NCT01653340 · rCM HF-SCS — A Feasibility Clinical Trial to Evaluate High Frequency Spinal Cord… | Migraine | À vérifier | Non applicable | COMPLETED | The purpose of this study is to assess short- and long-term safety, tolera… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| The Use of Autologous Mesenchymal Stem Cell Preparation for Treatment… NCT04064879 · NCT04064879 | Migraine | Traitement symptomatique · Thérapie cellulaire | Non applicable | SUSPENDED | The present study is being undertaken as a phase I study to determine the… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| Transcranial electrical stimulation NCT05099406 · Home-based Transcranial Stimulation in the Treatment of Patients With Refractory… | Migraine | Traitement symptomatique · Thérapie génique | Non applicable | UNKNOWN | Refractory chronic pain represents a serious and limiting health condition… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| Cadwell Cascade 32 PRO NCT07402954 · MMA-Stim — Stimulation of External Carotid Artery Circulation | Migraine | Traitement symptomatique · Thérapie génique | Non applicable | RECRUITING | This study is testing a new approach to help people with migraine headache… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:16 | Détail |
| embolization of middle meningeal arteries NCT07223008 · MMAE-Migraine — Bilateral Embolization of the Middle Meningeal Arteries for Refr… | Migraine | À vérifier | Non applicable | RECRUITING | This study is to test the safety and feasibility of a procedure called emb… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:16 | Détail |
| Pulsed Radiofrequency of the Sphenopalatine Ganglion NCT07370142 · SPG-PRF — Sphenopalatine Ganglion Pulsed Radiofrequency Treatment Outcomes | Migraine | Traitement symptomatique | Non applicable | COMPLETED | Purpose of the Study: This study aims to evaluate the clinical effectivene… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:16 | Détail |
| Amylin NCT07340788 · Amylin-Induced Migraine Attacks Without Aura | Migraine | À vérifier | Non applicable | NOT_YET_RECRUITING | Pramlintide is a peptide analogue of human amylin which is a vasoactive si… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:15 | Détail |
| Discussion on the Mechanism of Acupuncture on Patients with Paroxysma… NCT06676670 · NCT06676670 | Migraine | Thérapie génique | Non applicable | UNKNOWN | Background: Migraine is common but poorly managed with drugs. Acupuncture,… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:15 | Détail |
| FAST — Molecular Phenotyping of Migraine Patients According to Sex an… NCT06674772 · NCT06674772 | Migraine | À vérifier | À vérifier | RECRUITING | Patients will be asked to visit the study center 2 times, the first time f… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:15 | Détail |
| Fu's Subcutaneous Needling NCT07068815 · Efficacy and Mechanism of Fu's Subcutaneous Needling Treatment for Migraine With… | Migraine | Traitement symptomatique | Phase 1 | NOT_YET_RECRUITING | This study aimed to compare the analgesic efficacy and quality-of-life imp… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:15 | Détail |
| Levcromakalim NCT05211050 · SLIM — Effect of Sumatriptan on Levcromakalim-Induced Symptoms in Individuals Wi… | Migraine | Traitement symptomatique | Non applicable | COMPLETED | This study aims to explore the effect of Ivabradine on Levcromakalim-induc… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:15 | Détail |
| Myotensive Extraocular Muscle Techniques Added to Manual Therapy for… NCT07254598 · NCT07254598 | Migraine | Ralentissement de la progression · Traitement symptomatique · Thérapie génique | Non applicable | NOT_YET_RECRUITING | Migraine without aura is a highly prevalent and disabling primary headache… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:15 | Détail |
| Substance P NCT06959004 · Substance P-Induced Migraine Attacks Without Aura | Migraine | À vérifier | Non applicable | RECRUITING | Substance P is a neuropeptide implicated in the pathogenesis of headache.… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:15 | Détail |
| Almotriptan 12.5 Mg Oral Tablet NCT05214001 · ATOM — Evaluation of the Efficacy of Almotriptan and Ubrogepant for the Acute Tr… | Migraine | Traitement symptomatique | Phase 4 | TERMINATED | In a real-world population of adults with migraine, the investigators woul… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:14 | Détail |
| Be-Home-Kids — Feasibility and Effectiveness of Home-behavioral Progr… NCT04604977 · NCT04604977 | Migraine | Traitement symptomatique | Non applicable | COMPLETED | Chronic Migraine and Migraine without aura at high frequency are disabling… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:14 | Détail |
Découverte scientifique
Recherches et trouvailles 0
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune trouvaille ne correspond aux filtres. | |||||||
Bibliographie
Publications 661
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| The impact of timing, dosage, and duration of high-dose methylprednis… Methylprednisolone sodium succinate · PMID 42240612 | Migraine | À vérifier | Publication | PubMed | Voir la publication source The role of high-dose methylprednisolone sodium succinate (MPSS) in acute traumatic spinal cord injury (SCI) remains co… | The journal of spinal cord medicine 2026-08-08 01:00:09 | Source |
| Exploring the Sensitivity Limits of Neuronal Current Imaging With MRI… Visual Stimulation · PMID 42565248 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source Conventional BOLD-fMRI relies on hemodynamic responses that are temporally and spatially indirect markers of neural act… | Human brain mapping 2026-08-08 01:00:07 | Source |
| Investigating the Time-Course of Verticality Sensitivity Changes Duri… Visual Stimulation · PMID 42562383 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Verticality perception is a multisensory process that relies primarily on visual and vestibular input. Previous studies… | Multisensory research 2026-08-08 01:00:07 | Source |
| Evaluating clinical associations of immediate post-traumatic headache… Prospective ED Headache Cohort Study · PMID 42563150 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source Post-traumatic headache (PTH) is a frequent early consequence of head traumatic injury, yet emergency departments (EDs)… | The journal of headache and pain 2026-08-08 01:00:06 | Source |
| Retinal layers prognosticate cognitive progression independent of rel… Prospective ED Headache Cohort Study · PMID 42562954 | Migraine | Neuroprotection · Ralentissement de la progression · Thérapie génique | Publication | PubMed | Voir la publication source Optical coherence tomography (OCT) quantifies retinal neuroaxonal loss related to neurodegeneration in people with mult… | Journal of neurology 2026-08-08 01:00:06 | Source |
| Chronic xenogeneic GVHD after CAR T cell therapy limits long-term saf… antibodies against calcitonin-gene related peptide or its receptor · PMID 42566762 | Migraine | Immunomodulation · Thérapie cellulaire | Publication | PubMed | Voir la publication source The clinical successes of chimeric antigen receptor (CAR) T cells represent a major shift in immunotherapy. However, th… | Blood advances 2026-08-08 01:00:05 | Source |
| Comparative analyses of olfactory receptor repertoires in Schizothora… antibodies against calcitonin-gene related peptide or its receptor · PMID 42566844 | Migraine | À vérifier | Publication | PubMed | Voir la publication source The olfactory receptor (OR) genes constitute the molecular basis of fish olfaction, mediating survival behaviors and en… | Comparative biochemistry and physiology. Part D, Genom… 2026-08-08 01:00:05 | Source |
| Digital Remote Assessment of Motor and Speech Changes in Amyotrophic… Click Digital Therapeutic · PMID 42531420 | Migraine | Ralentissement de la progression · Thérapie génique | Publication | PubMed | Voir la publication source Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease with an active trial landscape that relies on the se… | JMIR formative research 2026-08-08 01:00:04 | Source |
| Short dextran-solanesol block copolymer as a bio-based platform for m… Click Digital Therapeutic · PMID 42493094 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Biohybrid block copolymer micelles from natural components hold great promise for biomedical applications; however, int… | Carbohydrate polymers 2026-08-08 01:00:04 | Source |
| Efficacy of MEDI0618, a pH-dependent monoclonal antibody targeting PA… MEDI0618 · PMID 40036725 | Migraine | Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Protease activated receptor 2 (PAR2) is a G-protein coupled receptor expressed in meningeal neurons, fibroblasts and ma… | Brain : a journal of neurology 2026-08-08 01:00:03 | Source |
| The development of proteinase-activated receptor-2 modulators and the… MEDI0618 · PMID 33242065 | Migraine | Immunomodulation | Publication | PubMed | Voir la publication source Protease-activated receptor-2 (PAR2) has been extensively studied since its discovery in the mid-1990. Despite the adva… | Biochemical Society transactions 2026-08-08 01:00:03 | Source |
| Delivery Model Matters for Digital Interventions in Pain Self-Managem… Care as usual · PMID 42475133 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Digital health interventions can improve access to and outreach of evidence-based support for people living with chroni… | Journal of medical Internet research 2026-08-08 01:00:02 | Source |
| Process Evaluation of a Problem-Solving Intervention with Workplace I… Care as usual · PMID 42541653 | Migraine | À vérifier | Publication | PubMed | Voir la publication source This process evaluation examined the implementation of a problem-solving intervention with workplace involvement (PSI-W… | Journal of occupational rehabilitation 2026-08-08 01:00:02 | Source |
| Ultrasound-Guided Stellate Ganglion Block in Fibromyalgia: A Randomiz… Ultrasound guided Stellate ganglion block · PMID 42530408 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Fibromyalgia is a chronic pain syndrome characterized by widespread pain, fatigue, and sleep disturbance. Many patients… | Pain research & management 2026-08-08 01:00:00 | Source |
| Post-dural Puncture Headache During Bacteraemia: Successful Managemen… ultrasound guided Greater occipital nerve block · PMID 42535063 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Epidural blood patch (EBP) is considered the most effective interventional treatment for post-dural puncture headache (… | Cureus 2026-08-08 00:59:59 | Source |
| Ultrasound-Guided Greater Occipital Nerve Block Across Headache Pheno… ultrasound guided Greater occipital nerve block · PMID 42533183 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Greater occipital nerve blocks (GONBs) are used across headache phenotypes, but short-term effectiveness and predictors… | Pain and therapy 2026-08-08 00:59:59 | Source |
| CGRP-pathway exposure during the pre-EBP interval in spontaneous intr… Galcanezumab · PMID 42432562 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Given hypothesized involvement of calcitonin gene-related peptide (CGRP) in trigeminovascular pain and the frequent mig… | BMC neurology 2026-08-08 00:59:58 | Source |
| Comparing synthetic and biological therapy for the treatment of clust… Galcanezumab · PMID 42493477 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Cluster headache is an extremely painful and severely disabling primary headache disorder that, despite its profound im… | Expert review of neurotherapeutics 2026-08-08 00:59:58 | Source |
| Compound Chamomile and Lidocaine Hydrochloride Gel in Oral Diseases:… Lidocaine Hydrochloride · PMID 42558651 | Migraine | Immunomodulation · Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Oral diseases frequently entail microbial infections or mucosal damage, typically accompanied by pain and discomfort. P… | Drug design, development and therapy 2026-08-08 00:59:57 | Source |
| Impact of Menthol Concentration on Ketoprofen Permeation and Photosta… Lidocaine Hydrochloride · PMID 42518428 | Migraine | Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Topical nonsteroidal anti-inflammatory drugs provide localized pain relief while reducing the risk of systemic adverse… | ACS omega 2026-08-08 00:59:57 | Source |
Exploration — prudence
Pistes exploratoires 5
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Bavisant BRAVEinMS — Bavisant | Migraine | Remyélinisation · Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Antagonisme du récepteur H3 de l’histamine Bavisant est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migra… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| Tol-MP Tol-MP — tolérance immunitaire spécifique de la myéline | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Microparticules biodégradables chargées en rapamycine et fonctionnalisées… Tol-MP est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migrain… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| SetPoint System SetPoint System — SetPoint Medical | Migraine | Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | re ApplicationsPublicationsCompanyCareersNewsGet startedGet startedNewsThe… SetPoint System est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation immunométabolique de la microglie 4-octyl itaconate et dérivés est étudié dans Sclérose latérale amyotrophique et documente plusieurs axes biologiques po… | Rapprochement Biomedical Watch · Sclérose latérale amy… | Détail |
| N-PPG N-PPG — modulation métabolique cérébrale | Migraine | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation métabolique et mitohormèse N-PPG est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être pertinents pour Migrai… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |