Vue transversale de la maladie
Migraine
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
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1236 résultats correspondants
· 45 visibles sur cette page
dans le périmètre Migraine
Niveau clinique
Études et traitements 570
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Prodigy internal pulse generator occipital nerve stimulator NCT07087678 · Occipital Nerve Stimulation in Chronic Migraine | Migraine | Traitement symptomatique | Non applicable | NOT_YET_RECRUITING | The goal of this clinical trial is to compare two different types of occip… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| Propofol NCT02492295 · Low-dose Propofol for the Treatment of Severe Refractory Migraine Headache in th… | Migraine | Immunomodulation · Traitement symptomatique | Non applicable | TERMINATED | Migraine headache is a frequent Emergency Department complaint. While firs… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| Psychological and Biological Markers of Refractory Migraine NCT05046119 · NCT05046119 | Migraine | Traitement symptomatique | À vérifier | UNKNOWN | The term "refractory" migraine describes a particularly aggressive form of… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| pulsed electromagnetic field NCT01670214 · Pulsed Electromagnetic Field Therapy in the Refractory Migraine | Migraine | À vérifier | Non applicable | COMPLETED | Pulsed electromagnetic field (PEMF) as prophylactic treatment may prevent… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| SCS NCT05382832 · BTX/SCS/TMig — Botox Vs Spinal Cord Stimulation in the Treatment of Refractory M… | Migraine | À vérifier | Non applicable | UNKNOWN | The clinical trial is focused on the treatment of selected patients with a… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| Senza™, High Frequency Spinal Cord Stimulator for Refractory Chronic… NCT01653340 · rCM HF-SCS — A Feasibility Clinical Trial to Evaluate High Frequency Spinal Cord… | Migraine | À vérifier | Non applicable | COMPLETED | The purpose of this study is to assess short- and long-term safety, tolera… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| The Use of Autologous Mesenchymal Stem Cell Preparation for Treatment… NCT04064879 · NCT04064879 | Migraine | Traitement symptomatique · Thérapie cellulaire | Non applicable | SUSPENDED | The present study is being undertaken as a phase I study to determine the… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| Transcranial electrical stimulation NCT05099406 · Home-based Transcranial Stimulation in the Treatment of Patients With Refractory… | Migraine | Traitement symptomatique · Thérapie génique | Non applicable | UNKNOWN | Refractory chronic pain represents a serious and limiting health condition… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| Cadwell Cascade 32 PRO NCT07402954 · MMA-Stim — Stimulation of External Carotid Artery Circulation | Migraine | Traitement symptomatique · Thérapie génique | Non applicable | RECRUITING | This study is testing a new approach to help people with migraine headache… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:16 | Détail |
| embolization of middle meningeal arteries NCT07223008 · MMAE-Migraine — Bilateral Embolization of the Middle Meningeal Arteries for Refr… | Migraine | À vérifier | Non applicable | RECRUITING | This study is to test the safety and feasibility of a procedure called emb… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:16 | Détail |
| Pulsed Radiofrequency of the Sphenopalatine Ganglion NCT07370142 · SPG-PRF — Sphenopalatine Ganglion Pulsed Radiofrequency Treatment Outcomes | Migraine | Traitement symptomatique | Non applicable | COMPLETED | Purpose of the Study: This study aims to evaluate the clinical effectivene… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:16 | Détail |
| Amylin NCT07340788 · Amylin-Induced Migraine Attacks Without Aura | Migraine | À vérifier | Non applicable | NOT_YET_RECRUITING | Pramlintide is a peptide analogue of human amylin which is a vasoactive si… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:15 | Détail |
| Discussion on the Mechanism of Acupuncture on Patients with Paroxysma… NCT06676670 · NCT06676670 | Migraine | Thérapie génique | Non applicable | UNKNOWN | Background: Migraine is common but poorly managed with drugs. Acupuncture,… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:15 | Détail |
| FAST — Molecular Phenotyping of Migraine Patients According to Sex an… NCT06674772 · NCT06674772 | Migraine | À vérifier | À vérifier | RECRUITING | Patients will be asked to visit the study center 2 times, the first time f… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:15 | Détail |
| Fu's Subcutaneous Needling NCT07068815 · Efficacy and Mechanism of Fu's Subcutaneous Needling Treatment for Migraine With… | Migraine | Traitement symptomatique | Phase 1 | NOT_YET_RECRUITING | This study aimed to compare the analgesic efficacy and quality-of-life imp… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:15 | Détail |
| Levcromakalim NCT05211050 · SLIM — Effect of Sumatriptan on Levcromakalim-Induced Symptoms in Individuals Wi… | Migraine | Traitement symptomatique | Non applicable | COMPLETED | This study aims to explore the effect of Ivabradine on Levcromakalim-induc… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:15 | Détail |
| Myotensive Extraocular Muscle Techniques Added to Manual Therapy for… NCT07254598 · NCT07254598 | Migraine | Ralentissement de la progression · Traitement symptomatique · Thérapie génique | Non applicable | NOT_YET_RECRUITING | Migraine without aura is a highly prevalent and disabling primary headache… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:15 | Détail |
| Substance P NCT06959004 · Substance P-Induced Migraine Attacks Without Aura | Migraine | À vérifier | Non applicable | RECRUITING | Substance P is a neuropeptide implicated in the pathogenesis of headache.… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:15 | Détail |
| Almotriptan 12.5 Mg Oral Tablet NCT05214001 · ATOM — Evaluation of the Efficacy of Almotriptan and Ubrogepant for the Acute Tr… | Migraine | Traitement symptomatique | Phase 4 | TERMINATED | In a real-world population of adults with migraine, the investigators woul… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:14 | Détail |
| Be-Home-Kids — Feasibility and Effectiveness of Home-behavioral Progr… NCT04604977 · NCT04604977 | Migraine | Traitement symptomatique | Non applicable | COMPLETED | Chronic Migraine and Migraine without aura at high frequency are disabling… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:14 | Détail |
Découverte scientifique
Recherches et trouvailles 0
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune trouvaille ne correspond aux filtres. | |||||||
Bibliographie
Publications 661
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Comparison of choroidal biomarkers and scleral thickness in keratocon… Optical Coherence Tomography (OCT) - Heidelberg SPECTRALIS HRA+OCT · PMID 42029908 | Migraine | À vérifier | Publication | PubMed | Voir la publication source PURPOSE: To investigate whether corneal collagen cross-linking (CXL) is associated with measurable remodeling of extra-… | Graefe's archive for clinical and experimental ophthal… 2026-08-16 19:24:04 | Source |
| Real-Time High-Resolution OCT for Imaging Retinal and Choroidal Blood… Optical Coherence Tomography (OCT) - Heidelberg SPECTRALIS HRA+OCT · PMID 42200766 | Migraine | À vérifier | Publication | PubMed | Voir la publication source To evaluate the feasibility of visualizing intravascular moving particles within retinal and choroidal vessels using re… | Investigative ophthalmology & visual science 2026-08-16 19:24:04 | Source |
| Caregiver Communication and Preparedness During Transitions in Care:… Corabotase dose A · PMID 40387577 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Patients with severe and life-limiting illnesses transitioning out of the hospital often rely on family caregivers (FCG… | Journal of palliative medicine 2026-08-16 19:24:01 | Source |
| Healthcare use and out-of-pocket costs for rural family caregivers an… Corabotase dose A · PMID 38698643 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Rural family caregivers (FCGs) in the United States often experience high economic costs. This randomized controlled tr… | Journal of the American Geriatrics Society 2026-08-16 19:24:01 | Source |
| Transitional Palliative Care for Family Caregivers: Outcomes From a R… Corabotase dose A · PMID 39111586 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Patients receiving inpatient palliative care often face physical and psychological uncertainties during transitions out… | Journal of pain and symptom management 2026-08-16 19:24:01 | Source |
| Effect of Extracorporeal Shock Wave Therapy Combined With Kinesio Tap… I-SPY-RCT — Intervention for Sleep and Pain in Youth: A Randomized Controlled Trial · PMID 418… | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source To evaluate the main effects of extracorporeal shock wave therapy (ESWT) and Kinesio taping (KT) and their interaction… | Archives of physical medicine and rehabilitation 2026-08-16 19:23:58 | Source |
| Efficacy and safety of transcutaneous electrical nerve stimulation in… I-SPY-RCT — Intervention for Sleep and Pain in Youth: A Randomized Controlled Trial · PMID 424… | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Itching is a common and distressing clinical manifestation following burns, which severely impairs patient quality of l… | BMJ open 2026-08-16 19:23:58 | Source |
| Preoperative photobiomodulation reduces pain in molar surgery: A, dou… I-SPY-RCT — Intervention for Sleep and Pain in Youth: A Randomized Controlled Trial · PMID 423… | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Postoperative pain, swelling, and functional limitations are common after mandibular third molar surgery, affecting rec… | Journal of dentistry 2026-08-16 19:23:58 | Source |
| Percutaneous closure strategy in patients with patent foramen ovale a… Transcatheter Closure of Patent Foramen Ovale · PMID 42218325 | Migraine | À vérifier | Publication | PubMed | Voir la publication source In transcatheter closure of patent foramen ovale (PFO) associated with cryptogenic stroke (CS), a small coexisting atri… | Cardiovascular intervention and therapeutics 2026-08-16 19:23:57 | Source |
| Steering clear of the Chiari network pitfall in the transoesophageal… Transcatheter Closure of Patent Foramen Ovale · PMID 41618633 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Résumé non disponible dans la base locale. | European heart journal. Cardiovascular Imaging 2026-08-16 19:23:57 | Source |
| Transcatheter Closure of Patent Foramen Ovale - A Single Center Exper… Transcatheter Closure of Patent Foramen Ovale · PMID 42092276 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source A patent foramen ovale (PFO) is present in 20%-30% of the adult population. It is usually found in patients incidentall… | The Journal of surgical research 2026-08-16 19:23:57 | Source |
| A comparison of reduced-dose prasugrel and standard-dose clopidogrel… Prasugrel 5mg · PMID 27823681 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Elderly patients display higher on clopidogrel platelet reactivity as compared with younger patients. Treatment with pr… | American heart journal 2026-08-16 19:23:56 | Source |
| Residual platelet reactivity and outcomes with 5 mg prasugrel therapy… Prasugrel 5mg · PMID 25139323 | Migraine | À vérifier | Publication | PubMed | Voir la publication source In acute coronary syndrome (ACS) patients older than 75 years old, prasugrel 10 mg maintenance therapy has shown less c… | International journal of cardiology 2026-08-16 19:23:56 | Source |
| The influence of body size on the pharmacodynamic and pharmacokinetic… Prasugrel 5mg · PMID 25022828 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Patients treated with clopidogrel who have higher body size exhibit greater platelet reactivity than patients with lowe… | Thrombosis research 2026-08-16 19:23:56 | Source |
| Efficacy, Safety, and Tolerability of Atogepant in Migraine Patients… Atogepant · PMID 42154195 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Atogepant is an oral calcitonin gene-related peptide (CGRP) receptor antagonist approved for migraine prevention; howev… | Neurology and therapy 2026-08-16 19:23:53 | Source |
| Online interest in calcitonin gene-related peptide-therapies: An info… Ubrogepant · PMID 42265869 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source To evaluate changes in public interest in calcitonin gene-related peptide therapies associated with major product lifec… | Headache 2026-08-16 19:23:50 | Source |
| Population Pharmacokinetics and Exposure-Response Analyses for Ubroge… Ubrogepant · PMID 42212509 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source A population pharmacokinetic (popPK) model was developed for ubrogepant using data from 10 Phase 1, 1 Phase 2, and 2 Ph… | Journal of clinical pharmacology 2026-08-16 19:23:50 | Source |
| The pharmacology of gepants in migraine: A scoping review on mechanis… Ubrogepant · PMID 42265882 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Calcitonin gene-related peptide (CGRP) is a key mediator in migraine pathophysiology, and the development of gepants, n… | Headache 2026-08-16 19:23:50 | Source |
| Clinical associations during the year before Parkinson's disease diag… Propranolol · PMID 42261249 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Characterizing clinical associations before Parkinson's disease (PD) diagnosis may improve understanding of the diagnos… | Annals of medicine 2026-08-16 19:23:49 | Source |
| Oral propranolol treatment safety in infantile hemangiomas. Propranolol · PMID 42179355 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Infantile hemangiomas are common and can be treated with propranolol. Cardiovascular side effects are a potential risk… | The Journal of dermatological treatment 2026-08-16 19:23:49 | Source |
Exploration — prudence
Pistes exploratoires 5
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Bavisant BRAVEinMS — Bavisant | Migraine | Remyélinisation · Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Antagonisme du récepteur H3 de l’histamine Bavisant est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migra… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| Tol-MP Tol-MP — tolérance immunitaire spécifique de la myéline | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Microparticules biodégradables chargées en rapamycine et fonctionnalisées… Tol-MP est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migrain… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| SetPoint System SetPoint System — SetPoint Medical | Migraine | Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | re ApplicationsPublicationsCompanyCareersNewsGet startedGet startedNewsThe… SetPoint System est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation immunométabolique de la microglie 4-octyl itaconate et dérivés est étudié dans Sclérose latérale amyotrophique et documente plusieurs axes biologiques po… | Rapprochement Biomedical Watch · Sclérose latérale amy… | Détail |
| N-PPG N-PPG — modulation métabolique cérébrale | Migraine | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation métabolique et mitohormèse N-PPG est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être pertinents pour Migrai… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |