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Périmètre

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Chaque choix s’applique immédiatement aux quatre sections. Le filtre « type de SEP » n’apparaît que lorsque la sclérose en plaques est sélectionnée.

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Essais et traitements4050Données cliniques et programmes
Recherches et trouvailles21Pipeline scientifique
Publications4595Références reliées aux maladies
Pistes exploratoires0Hypothèses non validées
8666 résultats correspondants · 41 visibles sur cette page dans le périmètre Toutes les maladies
Niveau clinique

Études et traitements 4050

Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.

Molécule / élément Maladie / population Objectif Phase / stade Statut / preuve Mécanisme / résumé Source Détail
Nurse Intervention Trial NCT06200480 · NCT06200480 Migraine À vérifier Non applicable TERMINATED This randomized open-label prospective study focus on headache patients in… À vérifier ClinicalTrials.gov 2026-08-13 14:28:09 Détail
occipital nerve stimulator NCT06022848 · Quantitative Sensory Testing and Occipital Nerve Stimulator Migraine Traitement symptomatique Non applicable COMPLETED The primary aim of this study is to assess the reversibility of a range of… À vérifier ClinicalTrials.gov 2026-08-13 14:28:09 Détail
OnabotulinumtoxinA NCT07535723 · Botulinum Toxin and/or Greater Occipital Nerve Block for Patients With Chronic M… Migraine À vérifier Non applicable NOT_YET_RECRUITING Chronic migraine is a debilitating neurological disorder that significantl… À vérifier ClinicalTrials.gov 2026-08-13 14:28:09 Détail
onabotulinumtoxinA prophylaxis with Lidocaine NCT07571889 · Topical Intranasal Anesthetic Block for Reducing the Pain of Botulinum Toxin Inj… Migraine Traitement symptomatique Non applicable RECRUITING People find the injections used in onabotulinumtoxinA (Botox®) uncomfortab… À vérifier ClinicalTrials.gov 2026-08-13 14:28:09 Détail
SOMATIN — Multimodal Therapy for Somatosensory Tinnitus NCT07468318 · NCT07468318 Migraine À vérifier Non applicable NOT_YET_RECRUITING Tinnitus (ringing or buzzing in the ears) affects approximately 10-15% of… À vérifier ClinicalTrials.gov 2026-08-13 14:28:09 Détail
Study on 30 Outpatients With Chronic Migraine Treated With Well-Being… NCT03404336 · NCT03404336 Migraine Ralentissement de la progression Non applicable RECRUITING Chronic migraine is a disabling type of migraine and is often resistant to… À vérifier ClinicalTrials.gov 2026-08-13 14:28:09 Détail
Vibrotactile Stimulation NCT04069572 · Vibratory Stimulation for the Treatment of Chronic Pain Migraine Traitement symptomatique Non applicable SUSPENDED The purpose of this study is to perform a first in man study with VCR stim… À vérifier ClinicalTrials.gov 2026-08-13 14:28:09 Détail
Virtual Reality NCT07374640 · Virtual Reality and Biofeedback for Adolescents With Chronic Dizziness Migraine Traitement symptomatique Phase 1 NOT_YET_RECRUITING Both persistent postural-perceptual dizziness (PPPD) and vestibular migrai… À vérifier ClinicalTrials.gov 2026-08-13 14:28:09 Détail
Efficacy of Smartphone Based Digital Application in Improving Headach… NCT04984720 · NCT04984720 Migraine Traitement symptomatique Non applicable COMPLETED Migraine is a common headache disorder and affects 1 in 5 adults during th… À vérifier ClinicalTrials.gov 2026-08-13 14:28:08 Détail
Monoclonal antibody anti-CGRP NCT06459648 · PREDI-CGRP — Study for Prevent Chronification Migraine Through Prediction of Res… Migraine À vérifier À vérifier RECRUITING Being able to predict each patients response to a specific treatment can m… À vérifier ClinicalTrials.gov 2026-08-13 14:28:08 Détail
Serotonergic Psychedelic NCT06624137 · Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics Migraine Thérapie génique À vérifier TERMINATED This is an observational study which does NOT directly administer a psyche… À vérifier ClinicalTrials.gov 2026-08-13 14:28:08 Détail
MRI NCT05654012 · Migraine in Adolescents Migraine Remyélinisation · Thérapie génique Non applicable RECRUITING The cognitive disorders of adult forms of myotonic dystrophies type 1 are… À vérifier ClinicalTrials.gov 2026-08-13 14:28:07 Détail
Psilocybin NCT06464367 · Mechanistic Studies of Psilocybin in Headache Disorders Migraine À vérifier Phase 1 RECRUITING This study aims to study the feasibility of psilocybin therapy for patient… À vérifier ClinicalTrials.gov 2026-08-13 14:28:07 Détail
Rimegepant NCT06641466 · A Study to Learn About the Study Medicine Called Rimegepant in Women When Used f… Migraine À vérifier Phase 3 RECRUITING The purpose of this study is to evaluate safety and tolerability of BHV-30… À vérifier ClinicalTrials.gov 2026-08-13 14:28:07 Détail
Tear Biomarkers for Migraine NCT07690696 · NCT07690696 Migraine À vérifier À vérifier NOT_YET_RECRUITING The goal of this observational monocentric study is to investigate tear an… À vérifier ClinicalTrials.gov 2026-08-13 14:28:07 Détail
Thermal stimuli NCT05738213 · IHS — Puberty, Sex Hormones and Pain Sensitivity in Adolescents With Migraine Migraine Traitement symptomatique Non applicable ACTIVE_NOT_RECRUITING The purpose of this research study is to investigate the relationships bet… À vérifier ClinicalTrials.gov 2026-08-13 14:28:07 Détail
Thermal stimuli NCT06785129 · EMC — Endometriosis and Migraine Migraine Traitement symptomatique À vérifier RECRUITING The purpose of this research study is to investigate the relationships bet… À vérifier ClinicalTrials.gov 2026-08-13 14:28:07 Détail
Yangxue Qingnao Granules (Pills) NCT05334927 · CHAIRS — China HeadAche DIsorders RegiStry Migraine À vérifier À vérifier RECRUITING It is planned to include 10000 patients. In the China HeadAche DIsorders R… À vérifier ClinicalTrials.gov 2026-08-13 14:28:07 Détail
3T Magnetic Resonance Imaging (MRI) NCT05823766 · Transforming Research and Clinical Knowledge in Traumatic Brain Injury Epileptog… Épilepsie À vérifier À vérifier ACTIVE_NOT_RECRUITING The overarching goal of this study is to improve understanding of the long… À vérifier ClinicalTrials.gov 2026-08-13 14:28:04 Détail
ALF-ME — AI-enhanced LF-MRI in Epilepsy NCT07717632 · NCT07717632 Épilepsie À vérifier Non applicable ACTIVE_NOT_RECRUITING The global burden of epilepsy is high affecting over 50 million people wor… À vérifier ClinicalTrials.gov 2026-08-13 14:28:04 Détail
Découverte scientifique

Recherches et trouvailles 21

Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.

Molécule / élément Maladie / population Objectif Phase / stade Statut / preuve Mécanisme / résumé Source Détail
4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation Sclérose latérale amyotrophique Neuroprotection · Immunomodulation Découverte fondamentale Exploratoire Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… Revue scientifique 2024-07-01 Détail
Bibliographie

Publications 4595

Références bibliographiques de la base locale et accès à leur source originale.

Molécule / élément Maladie / population Objectif Phase / stade Statut / preuve Mécanisme / résumé Source Détail
Effects of testosterone-augmented multimodal exercise intervention in… Whole-body Electrical Muscle Stimulation Exercise · PMID 41988780 Myasthénie À vérifier Publication PubMed Voir la publication source Spinal cord injury (SCI) leads to profound muscle atrophy, aerobic deconditioning, and metabolic dysfunction. Exercise-… The Journal of clinical endocrinology and metabolism 2026-09-20 04:37:05 Source
Feasibility and acceptability of whole-body electromyostimulation in… Whole-body Electrical Muscle Stimulation Exercise · PMID 42464389 Myasthénie À vérifier Publication PubMed Voir la publication source Evidence on the effectiveness of electromyostimulation (EMS) has been reported in pulmonary rehabilitation, but the ben… Pilot and feasibility studies 2026-09-20 04:37:05 Source
Vestibular contributions adapt to the balance strategies adopted duri… Whole-body Electrical Muscle Stimulation Exercise · PMID 42616645 Myasthénie À vérifier Publication PubMed Voir la publication source Vestibular contributions during walking are not uniform, but vary with gait phase, muscle group, and balance demands. M… Journal of neurophysiology 2026-09-20 04:37:05 Source
Clinical efficacy of abdominal moxibustion at the Zhongji (CV3) in co… Yangyin Roujin Decoction · PMID 42015783 Myopathies Neuroprotection · Traitement symptomatique Publication PubMed Voir la publication source To investigate the clinical effect of abdominal moxibustion at the Zhongji (CV3) combined with Yiqi Tonglin Yangyin dec… Journal of traditional Chinese medicine = Chung i tsa… 2026-09-20 04:37:03 Source
Yiqi Huoxue Yangyin Decoction Ameliorates Diabetic Nephropathy by Tar… Yangyin Roujin Decoction · PMID 42713045 Myopathies À vérifier Publication PubMed Voir la publication source This study aimed to investigate the protective effects and underlying mechanisms of Yiqi Huoxue Yangyin Decoction (YHY)… Diabetes, metabolic syndrome and obesity : targets and… 2026-09-20 04:37:03 Source
Yiqi Huoxue Yangyin Decoction attenuates diabetic nephropathy in mice… Yangyin Roujin Decoction · PMID 42016924 Myopathies Thérapie génique Publication PubMed Voir la publication source Diabetic nephropathy (DN) is a major complication of diabetes with limited therapeutic options. Yiqi Huoxue Yangyin Dec… Frontiers in pharmacology 2026-09-20 04:37:03 Source
Barcoded oligonucleotide system (BOLT) for targeted organ delivery. Immunotherapy · PMID 42733790 Cancer À vérifier Publication PubMed Voir la publication source The therapeutic potential of oligonucleotides (oligos) is limited by insufficient delivery to extrahepatic tissues. In… Bioactive materials 2026-09-20 04:36:56 Source
Dual metabolic checkpoint blockade a 3D-Printed metalloplatform remod… Immunotherapy · PMID 42724565 Cancer Immunomodulation Publication PubMed Voir la publication source The immunosuppressive tumor microenvironment limits the efficacy of therapies that target metabolism. Here we show a st… Bioactive materials 2026-09-20 04:36:56 Source
Oligosaccharide adjuvant-deferred antigen endocytosis promotes cross-… Immunotherapy · PMID 42751513 Cancer Immunomodulation · Thérapie génique Publication PubMed Voir la publication source Antigen cross-presentation by dendritic cells (DCs) is essential for inducing cytotoxic immune responses, which are cru… Bioactive materials 2026-09-20 04:36:56 Source
Feasibility and safety of early discharge after robot-assisted uro-on… Digital care pathway for hypertension · PMID 42671715 Hypertension artérielle À vérifier Publication PubMed Voir la publication source Early discharge after robot-assisted uro-oncologic surgery remains limited by concerns regarding patient safety and the… Journal of robotic surgery 2026-09-20 04:36:49 Source
HomeSafe: Postpartum Hypertensive Care Enabled by Electronic Health R… Digital care pathway for hypertension · PMID 41707683 Hypertension artérielle À vérifier Publication PubMed Voir la publication source The objective is to present stepwise refinements to , an Epic-tethered, population-health-coordinated postpartum pathwa… American journal of perinatology 2026-09-20 04:36:49 Source
Nutraceutical and functional food: efficacy against metabolic disorde… Digital care pathway for hypertension · PMID 42603698 Hypertension artérielle Neuroprotection · Immunomodulation Publication PubMed Voir la publication source The growing global emphasis on health consciousness has significantly increased demand for traditional and complementar… Journal of advanced research 2026-09-20 04:36:49 Source
Community-engaged design of a virtual diabetes prevention program int… Asynchronous communication with nurse · PMID 42288862 Hypertension artérielle À vérifier Publication PubMed Voir la publication source The Diabetes Prevention Program (DPP) is an evidence-based approach to prevent Type 2 Diabetes (T2D), the leading cause… BMC health services research 2026-09-20 04:36:48 Source
Evolving Lung Cancer Navigator Practice Through Targeted Professional… Asynchronous communication with nurse · PMID 42463006 Cancer À vérifier Publication PubMed Voir la publication source Lung cancer remains the leading cause of cancer deaths worldwide, and it has persistent disparities in detection, treat… Chest 2026-09-20 04:36:48 Source
Mass casualty training for prehospital and emergency providers in Kig… Asynchronous communication with nurse · PMID 42751142 Hypertension artérielle À vérifier Publication PubMed Voir la publication source A mass casualty incident (MCI) occurs when the number of patients exceeds available healthcare resources, placing signi… African journal of emergency medicine : Revue africain… 2026-09-20 04:36:48 Source
Innovating a Teach-Back Model for Community Health Workers Led Health… Health Literacy Project · PMID 40194526 Épilepsie À vérifier Publication PubMed Voir la publication source From 2021 to 2023, the City of Albuquerque, the University of New Mexico (UNM) Office for Community Health, the UNM Hos… Health literacy research and practice 2026-09-20 04:36:34 Source
Carotid intima-media thickness may be an early biomarker for cardiova… Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy · PMID 41026111 Épilepsie À vérifier Publication PubMed Voir la publication source To assess early signs of atherosclerosis following long-term treatment with the ketogenic diet therapy due to concerns… Epilepsia open 2026-09-20 04:36:33 Source
Impact of low-carbohydrate diet on health status: an umbrella review. Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy · PMID 39385794 Cancer À vérifier Publication PubMed Voir la publication source The prevalence of diet-related non-communicable diseases has increased. A low-carbohydrate diet (LCDs) is one of the mo… Frontiers in nutrition 2026-09-20 04:36:33 Source
The effect of anti-seizure medications on lipid values in adults with… Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy · PMID 37244221 Épilepsie À vérifier Publication PubMed Voir la publication source Certain anti-seizure medications (ASMs) adversely impact lipid values. Here, we explored the impact of ASMs on lipid va… Epilepsy & behavior : E&B 2026-09-20 04:36:33 Source
Possible role of locus coeruleus neuronal loss in age-related memory… The Role of the Locus Coeruleus in Age-related Distractibility · PMID 37694113 Maladie d’Alzheimer Immunomodulation Publication PubMed Voir la publication source Aging is associated with a decline in cognitive abilities, including memory and attention. It is generally accepted tha… Frontiers in neuroscience 2026-09-20 04:36:30 Source
Exploration — prudence

Pistes exploratoires 0

Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.

Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
Molécule / élément Maladie / population Objectif Phase / stade Statut / preuve Mécanisme / résumé Source Détail
Aucune piste exploratoire ne correspond aux filtres.