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Migraine
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
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1236 résultats correspondants
· 45 visibles sur cette page
dans le périmètre Migraine
Niveau clinique
Études et traitements 570
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| rizatriptan benzoate NCT01004263 · A Study to Evaluate the Safety and Tolerability of Rizatriptan for Long Term Tre… | Migraine | À vérifier | Phase 3 | COMPLETED | To provide long term safety data for rizatriptan in children and adolescen… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:14 | Détail |
| SAMCO-MIG — Sensitivity to Acute Cerebral Ischemia in Migrainers NCT03301441 · NCT03301441 | Migraine | À vérifier | À vérifier | UNKNOWN | Sensitivity to Acute Middle cerebral or intracranial Carotid artery Occlus… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:14 | Détail |
| Tizanidine Hydrochloride NCT05484349 · TIzanidine for the Preventive Treatment of Episodic MigrainE （TIME） | Migraine | À vérifier | Phase 3 | UNKNOWN | In this study,189 adult migraine patients aged 18-65 years (diagnosed with… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:14 | Détail |
| "Longitudinal Analysis of Amylin Levels in Migraine Patients Undergoi… NCT06692088 · NCT06692088 | Migraine | À vérifier | À vérifier | NOT_YET_RECRUITING | Migraine, a complex and multifaceted disorder, remains only partially unde… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:12 | Détail |
| 90mg Idebenone NCT04151472 · Idebenone for the Preventive Treatment of Migraine | Migraine | À vérifier | Phase 3 | RECRUITING | Idebenone improves energy metabolism similarly to Coenzyme Q10, which is e… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:12 | Détail |
| Atogepant NCT05264129 · TANDEM — Study to Assess Adverse Events When Ubrogepant Tablets in Combination W… | Migraine | Traitement symptomatique | Phase 4 | COMPLETED | A migraine attack is a moderate or severe headache that usually occurs on… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:12 | Détail |
| Atogepant 60 mg NCT04437433 · JPN ATO OLE — A Study Evaluating Oral Atogepant for the Prevention of Migraine i… | Migraine | À vérifier | Phase 3 | COMPLETED | This goal of this study is to compare three medications used for migraine… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:12 | Détail |
| Atogepant 60 mg NCT06882122 · ATOM — Neurophysiological and Biomolecular Effects of Atogepant in Episodic Migr… | Migraine | À vérifier | À vérifier | RECRUITING | This goal of this study is to compare three medications used for migraine… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:12 | Détail |
| Craniocervical Flexion Training for Reducing Migraine Headaches and D… NCT06751732 · NCT06751732 | Migraine | Ralentissement de la progression · Thérapie génique | Non applicable | COMPLETED | Migraine, a leading cause of disability globally, necessitates effective i… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:12 | Détail |
| Erenumab NCT04628429 · CGRP-1 — CGRP Inhibition, Autonomic Function, and Migraine | Migraine | Traitement symptomatique | À vérifier | RECRUITING | The primary objective of this study is to evaluate the treatment benefit o… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:12 | Détail |
| Erenumab NCT04084314 · APOLLON — Assessment of Prolonged Safety and tOLerability of in Migraine Patient… | Migraine | Traitement symptomatique | Phase 4 | COMPLETED | The primary objective of this study is to evaluate the treatment benefit o… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:12 | Détail |
| Erenumab NCT04825678 · A Study to Evaluate Treatment Satisfaction With Erenumab in Participants With Mi… | Migraine | Traitement symptomatique | Phase 4 | COMPLETED | The primary objective of this study is to evaluate the treatment benefit o… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:12 | Détail |
| Greater Occipital Nerve Blockade and Sphenopalatine Ganglion Blockade… NCT06997562 · NCT06997562 | Migraine | Ralentissement de la progression | Non applicable | COMPLETED | This study compares the effectiveness of greater occipital nerve blockade… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:12 | Détail |
| Lidocaine 4% Topical Application Cream [LMX 4] NCT03526874 · Occipital Blocks for Acute Migraine | Migraine | Traitement symptomatique | Phase 3 | COMPLETED | Migraine affects 10-28% of children and adolescents and yet 20-30% of pati… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:12 | Détail |
| MAbs NCT06549270 · SPHERA_WP1_1 — Biochemical Profiling of Migraine Patients | Migraine | Thérapie génique | À vérifier | RECRUITING | Aim of the study was to assess a potential dysfunction of the endocannabid… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:12 | Détail |
| MENAURIC — Treatment of Episodic Migraine With AURICular Neuromodulat… NCT06623188 · NCT06623188 | Migraine | Traitement symptomatique · Thérapie génique | Non applicable | RECRUITING | Migraine is a ubiquitous pathology affecting approximately 1 billion indiv… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:12 | Détail |
| Mi-Helper NCT06051604 · Mi-Helper Transnasal Cooling for Acute Treatment of Migraine | Migraine | À vérifier | Non applicable | COMPLETED | This is a prospective, double-blind, sham-controlled, randomized, decentra… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:12 | Détail |
| NAMIKOS — Integrative and Complementary Therapy for Episodic Migraine… NCT06764914 · NCT06764914 | Migraine | Traitement symptomatique · Thérapie génique | À vérifier | NOT_YET_RECRUITING | This study is a monocentric uncontrolled observational study to evaluate a… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:12 | Détail |
| neuromodulation for episodic migraine headache NCT01899040 · A Non-Invasive Neuromodulation Device for Treatment of Migraine Headache | Migraine | À vérifier | Non applicable | COMPLETED | This is a randomized, blinded study designed to assess the efficacy of a p… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:12 | Détail |
| Pain Control in Episodic and Chronic Migraine NCT06599905 · NCT06599905 | Migraine | Traitement symptomatique | Non applicable | COMPLETED | The phenomenon of offset analgesia (OA) refers to a disproportionately lar… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:12 | Détail |
Découverte scientifique
Recherches et trouvailles 0
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune trouvaille ne correspond aux filtres. | |||||||
Bibliographie
Publications 661
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Active machine learning model for the dynamic simulation and growth m… TI-001 · PMID 38184678 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Substrate-catalyzed growth offers a highly promising approach for the controlled synthesis of carbon nanostructures. Ho… | Nature communications 2026-08-08 00:59:56 | Source |
| Combined Occipital Nerve and Sphenopalatine Ganglion Neuromodulation… Occipital Nerve Stimulation · PMID 42100751 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Craniofacial complex regional pain syndrome (CRPS) is a rare, diagnostically challenging condition characterized by sym… | Local and regional anesthesia 2026-08-08 00:59:56 | Source |
| Comparative Efficacy and Acceptability of Noninvasive Brain Stimulati… Occipital Nerve Stimulation · PMID 42473074 | Migraine | À vérifier | Publication | PubMed | Voir la publication source This network meta-analysis (NMA) aimed to compare and rank the efficacy and acceptability of different noninvasive brai… | Brain and behavior 2026-08-08 00:59:56 | Source |
| TiO2 nanotubes: interdependence of substrate grain orientation and gr… TI-001 · PMID 25545715 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Highly ordered arrays of TiO2 nanotubes can be produced by self-organized anodic growth. It is desirable to identify ke… | ACS applied materials & interfaces 2026-08-08 00:59:56 | Source |
| International Headache society evidence-based guidelines on the use o… Nerivio Migra-1 Sham device · PMID 41117312 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source ObjectiveTo develop evidence-based clinical practice guidelines for non-invasive neuromodulation devices in acute and p… | Cephalalgia : an international journal of headache 2026-08-08 00:59:54 | Source |
| Plasma Phosphorylated Tau 217 in Participants at Risk for Chronic Tra… BE WELL With Migraine: Brain Education and WELLness With Migraine · PMID 42440317 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source In vivo biomarkers for detecting neuropathologies from repetitive head impacts (RHI), including chronic traumatic encep… | JAMA network open 2026-08-08 00:59:53 | Source |
| Weight loss with atogepant in the long-term treatment of migraine: An… BE WELL With Migraine: Brain Education and WELLness With Migraine · PMID 42396885 | Migraine | À vérifier | Publication | PubMed | Voir la publication source To assess weight loss with atogepant 60 mg once daily during long-term treatment of chronic migraine (CM) and episodic… | Headache 2026-08-08 00:59:53 | Source |
| Cellulose and Its Derivatives in Drug Delivery: Recent Advances and A… sumatriptan succinate · PMID 42198288 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Drug delivery systems have long faced a fundamental challenge: achieving high drug-loading efficiency, precise control… | Pharmaceutics 2026-08-08 00:59:51 | Source |
| Spatial metabolomics combined with MALDI-MSI unveils gut-brain axis m… sumatriptan succinate · PMID 41619552 | Migraine | Immunomodulation · Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Migraine is a highly disabling neurological disorder characterized by recurrent headaches and complex metabolic disturb… | Phytomedicine : international journal of phytotherapy… 2026-08-08 00:59:51 | Source |
| Drugs targeting nitric oxide synthase for migraine treatment. NXN-188 · PMID 24818644 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Ample evidence that nitric oxide (NO) is a causative molecule in migraine has encouraged research to develop drugs that… | Expert opinion on investigational drugs 2026-08-08 00:59:50 | Source |
| The nitric oxide synthase inhibitor and serotonin-receptor agonist NX… NXN-188 · PMID 29913885 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Background and aims NXN-188 is a combined neuronal nitric oxide synthase (nNOS) inhibitor and 5HT-1B/1D receptor agonis… | Scandinavian journal of pain 2026-08-08 00:59:50 | Source |
| Identifying central positional vertigo to prevent diagnostic pitfalls… Vestibular System in Migrainous Vertigo Patients · PMID 42564662 | Migraine | À vérifier | Publication | PubMed | Voir la publication source This case series highlights the critical role of radiological imaging in patients presenting with positional vertigo in… | Radiology case reports 2026-08-08 00:59:48 | Source |
| Quantitative pupillometry as a marker of autonomic dysregulation in v… Vestibular System in Migrainous Vertigo Patients · PMID 42548108 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source Vestibular migraine (VM) has been associated with altered central sensory processing; however, objective measures of au… | Journal of oral & facial pain and headache 2026-08-08 00:59:48 | Source |
| Arterial hepatic perfusion is preserved during early resuscitation af… blood withdrawal · PMID 42431156 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Hemorrhagic shock is a major contributor to morbidity and mortality after polytrauma and plays a central role in the de… | Injury 2026-08-08 00:59:47 | Source |
| Long peripheral catheters for short-term vascular access: A 7-day obs… blood withdrawal · PMID 42438309 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source Long peripheral catheters are increasingly used as an alternative to short peripheral catheters for short-term intraven… | The journal of vascular access 2026-08-08 00:59:47 | Source |
| A Real-World Evidence Study on US Patients Demonstrating Safety of Hi… Nerivio ® · PMID 41886224 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Remote electrical neuromodulation (REN) is an FDA-cleared, nonsignificant-risk, drug-free, prescribed wearable device (… | Pain and therapy 2026-08-08 00:59:45 | Source |
| Association of adverse childhood experiences with physical illness an… Brief Interventions in Chronic Migraine · PMID 40194777 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Adverse childhood experiences (ACEs) are highly prevalent and associated with life-long health consequences. Here, we i… | European journal of public health 2026-08-08 00:59:45 | Source |
| Non-Pharmacological Treatment of Primary Headaches-A Focused Review. Brief Interventions in Chronic Migraine · PMID 37891800 | Migraine | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Headache disorders are a significant global health burden, leading to reduced quality of life. While vast pharmacologic… | Brain sciences 2026-08-08 00:59:45 | Source |
| U.S. Veterans Using Remote Electrical Neuromodulation for Migraine: A… Nerivio ® · PMID 42520312 | Migraine | Ralentissement de la progression · Traitement symptomatique | Publication | PubMed | Voir la publication source Among U.S. veterans, migraine and other headache disorders are common, and frequently co-occur with other comorbidities… | Military medicine 2026-08-08 00:59:45 | Source |
| 2025 guideline update to acute treatment of migraine for adults in th… Greater Occipital Nerve Block with dexamethasone and lidocaine · PMID 41321235 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source To update the 2016 American Headache Society (AHS) guideline on parenteral pharmacologic therapies for the management o… | Headache 2026-08-08 00:59:43 | Source |
Exploration — prudence
Pistes exploratoires 5
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Bavisant BRAVEinMS — Bavisant | Migraine | Remyélinisation · Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Antagonisme du récepteur H3 de l’histamine Bavisant est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migra… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| Tol-MP Tol-MP — tolérance immunitaire spécifique de la myéline | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Microparticules biodégradables chargées en rapamycine et fonctionnalisées… Tol-MP est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migrain… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| SetPoint System SetPoint System — SetPoint Medical | Migraine | Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | re ApplicationsPublicationsCompanyCareersNewsGet startedGet startedNewsThe… SetPoint System est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation immunométabolique de la microglie 4-octyl itaconate et dérivés est étudié dans Sclérose latérale amyotrophique et documente plusieurs axes biologiques po… | Rapprochement Biomedical Watch · Sclérose latérale amy… | Détail |
| N-PPG N-PPG — modulation métabolique cérébrale | Migraine | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation métabolique et mitohormèse N-PPG est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être pertinents pour Migrai… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |