Vue transversale de la maladie
Migraine
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
Périmètre
Filtrer toute la vue
Chaque choix s’applique immédiatement aux quatre sections. Le filtre « type de SEP » n’apparaît que lorsque la sclérose en plaques est sélectionnée.
1236 résultats correspondants
· 45 visibles sur cette page
dans le périmètre Migraine
Niveau clinique
Études et traitements 570
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Ubrogepant NCT05125302 · Ubro Peds — Study to Assess Adverse Events and Disease Activity of Oral Ubrogepa… | Migraine | À vérifier | Phase 3 | RECRUITING | Migraine is a common neurological disorder typically characterized by atta… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:03 | Détail |
| Elismetrep NCT07674654 · A Long-Term Safety Study of Elismetrep (K-304) in the Acute Treatment of Migraine | Migraine | À vérifier | Phase 3 | RECRUITING | This is a long-term safety study to evaluate the safety and tolerability o… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:02 | Détail |
| Eptinezumab NCT07191145 · Eary Infusion of Eptinezumab for TreatmEnt of ACute Post-Traumatic Headaches (EL… | Migraine | Traitement symptomatique | Phase 3 | NOT_YET_RECRUITING | Most individuals with mild traumatic brain injury (mTBI) experience post-t… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:02 | Détail |
| greater occipital nerve block NCT07763678 · Efficacy of Ultrasound-Guided Combined Greater Occipital Nerve Block and Greater… | Migraine | Ralentissement de la progression · Traitement symptomatique | Phase 4 | NOT_YET_RECRUITING | Migraine is one of the most prevalent neurological disorders worldwide and… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:02 | Détail |
| Neurostimulator NCT07719608 · RECLAIM-II — A Pivotal Clinical Study to Evaluate the MySalvia System for the Tr… | Migraine | À vérifier | Non applicable | RECRUITING | The purpose of this pivotal clinical study is to evaluate the safety and e… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:02 | Détail |
| NIMH Rhythms and Blues Study: A Prospective Natural History Study of… NCT05669703 · NCT05669703 | Migraine | Thérapie génique | À vérifier | RECRUITING | Background: Mood disorders, such as bipolar disorder, can have serious eff… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:02 | Détail |
| The Effect of Two Different Massages on Migraine NCT05452330 · NCT05452330 | Migraine | Ralentissement de la progression · Traitement symptomatique | Non applicable | COMPLETED | The study aims to compare the effects of connective tissue massage on pain… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:02 | Détail |
| VNS device NCT02791893 · Vagus Nerve Stimulation: Treatment for Gulf Veterans With Gulf War Illness | Sclérose en plaques | Traitement symptomatique | Non applicable | COMPLETED | The researchers propose studying Gulf veterans with Gulf War Illness (GWI)… À vérifier | ClinicalTrials.gov 2026-08-13 14:16:47 | Détail |
| Sham Transcranial direct current stimulation Étude non communiquée | Migraine · Sclérose en plaques | À vérifier | Non applicable | Actif | This research is being done to determine whether transcranial direct curre… À vérifier | ClinicalTrials.gov 2026-08-12 | Détail |
| Greater Auricular Nerve Block Étude non communiquée | Migraine | Ralentissement de la progression · Traitement symptomatique | Phase 4 | Prévu | Migraine is one of the most prevalent neurological disorders worldwide and… À vérifier | ClinicalTrials.gov 2026-08-10 | Détail |
| Saline 0.9% Étude non communiquée | Migraine | Traitement symptomatique | Phase 2 | Prévu | The goal of this double-blinded, randomized placebo controlled clinical tr… À vérifier | ClinicalTrials.gov 2026-08-10 | Détail |
| H.P. Acthar Gel NCT01813591 · A Two-Arm Study Evaluation H.P. Acthar Injection Gel in Treatment of Chronic Mig… | Migraine | Immunomodulation · Traitement symptomatique | Phase 2 | COMPLETED | This small study is to investigate the efficacy of Acthar in the treatment… À vérifier | ClinicalTrials.gov 2026-08-08 00:54:17 | Détail |
| Lidocaine Hydrochloride NCT06462781 · LIGHT 1 — Localized Injection of Lidocaine and Glucocorticoid for Headache Treat… | Migraine | Traitement symptomatique | Phase 1 | COMPLETED | This randomized clinical trial will aim to compare the effectiveness of dr… À vérifier | ClinicalTrials.gov 2026-08-08 00:54:17 | Détail |
| antibodies against calcitonin-gene related peptide or its receptor NCT04019496 · Neurophysiology of Prophylactic Treatment in Migraine | Migraine | Traitement symptomatique | À vérifier | COMPLETED | This study aims to improve the pathophysiological understanding of migrain… À vérifier | ClinicalTrials.gov 2026-08-08 00:54:16 | Détail |
| Care as usual NCT03395457 · Tertiary Care With or Without Manual Therapy for Chronic Migraine | Migraine | À vérifier | NA | COMPLETED | The aim of this study is to determine if adding manual therapy to care as… À vérifier | ClinicalTrials.gov 2026-08-08 00:54:16 | Détail |
| Click Digital Therapeutic NCT06004388 · Study of Two Digital Therapeutics for the Prevention of Episodic Migraine Receiv… | Migraine | À vérifier | Phase 3 | COMPLETED | Randomized study of two digital therapeutics for the prevention of episodi… À vérifier | ClinicalTrials.gov 2026-08-08 00:54:16 | Détail |
| Evaluation of a Mind-body Based Application for the Treatment of Chro… NCT05090683 · NCT05090683 | Migraine | Traitement symptomatique | NA | COMPLETED | We are investigating the effects of a mind-body based mobile application o… À vérifier | ClinicalTrials.gov 2026-08-08 00:54:16 | Détail |
| Lasmiditan NCT05903040 · Ditan Acute tReatments: Effectiveness and Tolerability (DART) | Migraine | À vérifier | À vérifier | COMPLETED | The purpose of this study is to evaluate the efficacy and safety of a rang… À vérifier | ClinicalTrials.gov 2026-08-08 00:54:16 | Détail |
| MEDI0618 NCT06602479 · AURORA — A Study to Investigate the Safety and Efficacy of MEDI0618 Compared to… | Migraine | À vérifier | Phase 2 | RECRUITING | The purpose of this Phase 2 study is to evaluate the safety and efficacy o… À vérifier | ClinicalTrials.gov 2026-08-08 00:54:16 | Détail |
| PRESTO — IndoProCaf Effervescent Tablets Effectiveness in Acute Treat… NCT02115269 · PRESTO — IndoProCaf Effervescent Tablets Effectiveness in Acute Treatment of Mig… | Migraine | À vérifier | À vérifier | COMPLETED | Headaches are a common medical problem that physicians frequently encounte… À vérifier | ClinicalTrials.gov 2026-08-08 00:54:16 | Détail |
Découverte scientifique
Recherches et trouvailles 0
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune trouvaille ne correspond aux filtres. | |||||||
Bibliographie
Publications 661
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| The impact of timing, dosage, and duration of high-dose methylprednis… Methylprednisolone sodium succinate · PMID 42240612 | Migraine | À vérifier | Publication | PubMed | Voir la publication source The role of high-dose methylprednisolone sodium succinate (MPSS) in acute traumatic spinal cord injury (SCI) remains co… | The journal of spinal cord medicine 2026-08-08 01:00:09 | Source |
| Exploring the Sensitivity Limits of Neuronal Current Imaging With MRI… Visual Stimulation · PMID 42565248 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source Conventional BOLD-fMRI relies on hemodynamic responses that are temporally and spatially indirect markers of neural act… | Human brain mapping 2026-08-08 01:00:07 | Source |
| Investigating the Time-Course of Verticality Sensitivity Changes Duri… Visual Stimulation · PMID 42562383 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Verticality perception is a multisensory process that relies primarily on visual and vestibular input. Previous studies… | Multisensory research 2026-08-08 01:00:07 | Source |
| Evaluating clinical associations of immediate post-traumatic headache… Prospective ED Headache Cohort Study · PMID 42563150 | Migraine | Thérapie génique | Publication | PubMed | Voir la publication source Post-traumatic headache (PTH) is a frequent early consequence of head traumatic injury, yet emergency departments (EDs)… | The journal of headache and pain 2026-08-08 01:00:06 | Source |
| Retinal layers prognosticate cognitive progression independent of rel… Prospective ED Headache Cohort Study · PMID 42562954 | Migraine | Neuroprotection · Ralentissement de la progression · Thérapie génique | Publication | PubMed | Voir la publication source Optical coherence tomography (OCT) quantifies retinal neuroaxonal loss related to neurodegeneration in people with mult… | Journal of neurology 2026-08-08 01:00:06 | Source |
| Chronic xenogeneic GVHD after CAR T cell therapy limits long-term saf… antibodies against calcitonin-gene related peptide or its receptor · PMID 42566762 | Migraine | Immunomodulation · Thérapie cellulaire | Publication | PubMed | Voir la publication source The clinical successes of chimeric antigen receptor (CAR) T cells represent a major shift in immunotherapy. However, th… | Blood advances 2026-08-08 01:00:05 | Source |
| Comparative analyses of olfactory receptor repertoires in Schizothora… antibodies against calcitonin-gene related peptide or its receptor · PMID 42566844 | Migraine | À vérifier | Publication | PubMed | Voir la publication source The olfactory receptor (OR) genes constitute the molecular basis of fish olfaction, mediating survival behaviors and en… | Comparative biochemistry and physiology. Part D, Genom… 2026-08-08 01:00:05 | Source |
| Digital Remote Assessment of Motor and Speech Changes in Amyotrophic… Click Digital Therapeutic · PMID 42531420 | Migraine | Ralentissement de la progression · Thérapie génique | Publication | PubMed | Voir la publication source Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease with an active trial landscape that relies on the se… | JMIR formative research 2026-08-08 01:00:04 | Source |
| Short dextran-solanesol block copolymer as a bio-based platform for m… Click Digital Therapeutic · PMID 42493094 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Biohybrid block copolymer micelles from natural components hold great promise for biomedical applications; however, int… | Carbohydrate polymers 2026-08-08 01:00:04 | Source |
| Efficacy of MEDI0618, a pH-dependent monoclonal antibody targeting PA… MEDI0618 · PMID 40036725 | Migraine | Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Protease activated receptor 2 (PAR2) is a G-protein coupled receptor expressed in meningeal neurons, fibroblasts and ma… | Brain : a journal of neurology 2026-08-08 01:00:03 | Source |
| The development of proteinase-activated receptor-2 modulators and the… MEDI0618 · PMID 33242065 | Migraine | Immunomodulation | Publication | PubMed | Voir la publication source Protease-activated receptor-2 (PAR2) has been extensively studied since its discovery in the mid-1990. Despite the adva… | Biochemical Society transactions 2026-08-08 01:00:03 | Source |
| Delivery Model Matters for Digital Interventions in Pain Self-Managem… Care as usual · PMID 42475133 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Digital health interventions can improve access to and outreach of evidence-based support for people living with chroni… | Journal of medical Internet research 2026-08-08 01:00:02 | Source |
| Process Evaluation of a Problem-Solving Intervention with Workplace I… Care as usual · PMID 42541653 | Migraine | À vérifier | Publication | PubMed | Voir la publication source This process evaluation examined the implementation of a problem-solving intervention with workplace involvement (PSI-W… | Journal of occupational rehabilitation 2026-08-08 01:00:02 | Source |
| Ultrasound-Guided Stellate Ganglion Block in Fibromyalgia: A Randomiz… Ultrasound guided Stellate ganglion block · PMID 42530408 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Fibromyalgia is a chronic pain syndrome characterized by widespread pain, fatigue, and sleep disturbance. Many patients… | Pain research & management 2026-08-08 01:00:00 | Source |
| Post-dural Puncture Headache During Bacteraemia: Successful Managemen… ultrasound guided Greater occipital nerve block · PMID 42535063 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Epidural blood patch (EBP) is considered the most effective interventional treatment for post-dural puncture headache (… | Cureus 2026-08-08 00:59:59 | Source |
| Ultrasound-Guided Greater Occipital Nerve Block Across Headache Pheno… ultrasound guided Greater occipital nerve block · PMID 42533183 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Greater occipital nerve blocks (GONBs) are used across headache phenotypes, but short-term effectiveness and predictors… | Pain and therapy 2026-08-08 00:59:59 | Source |
| CGRP-pathway exposure during the pre-EBP interval in spontaneous intr… Galcanezumab · PMID 42432562 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Given hypothesized involvement of calcitonin gene-related peptide (CGRP) in trigeminovascular pain and the frequent mig… | BMC neurology 2026-08-08 00:59:58 | Source |
| Comparing synthetic and biological therapy for the treatment of clust… Galcanezumab · PMID 42493477 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Cluster headache is an extremely painful and severely disabling primary headache disorder that, despite its profound im… | Expert review of neurotherapeutics 2026-08-08 00:59:58 | Source |
| Compound Chamomile and Lidocaine Hydrochloride Gel in Oral Diseases:… Lidocaine Hydrochloride · PMID 42558651 | Migraine | Immunomodulation · Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Oral diseases frequently entail microbial infections or mucosal damage, typically accompanied by pain and discomfort. P… | Drug design, development and therapy 2026-08-08 00:59:57 | Source |
| Impact of Menthol Concentration on Ketoprofen Permeation and Photosta… Lidocaine Hydrochloride · PMID 42518428 | Migraine | Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Topical nonsteroidal anti-inflammatory drugs provide localized pain relief while reducing the risk of systemic adverse… | ACS omega 2026-08-08 00:59:57 | Source |
Exploration — prudence
Pistes exploratoires 5
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Bavisant BRAVEinMS — Bavisant | Migraine | Remyélinisation · Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Antagonisme du récepteur H3 de l’histamine Bavisant est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migra… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| Tol-MP Tol-MP — tolérance immunitaire spécifique de la myéline | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Microparticules biodégradables chargées en rapamycine et fonctionnalisées… Tol-MP est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migrain… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| SetPoint System SetPoint System — SetPoint Medical | Migraine | Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | re ApplicationsPublicationsCompanyCareersNewsGet startedGet startedNewsThe… SetPoint System est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation immunométabolique de la microglie 4-octyl itaconate et dérivés est étudié dans Sclérose latérale amyotrophique et documente plusieurs axes biologiques po… | Rapprochement Biomedical Watch · Sclérose latérale amy… | Détail |
| N-PPG N-PPG — modulation métabolique cérébrale | Migraine | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation métabolique et mitohormèse N-PPG est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être pertinents pour Migrai… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |