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Périmètre

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Chaque choix s’applique immédiatement aux quatre sections. Le filtre « type de SEP » n’apparaît que lorsque la sclérose en plaques est sélectionnée.

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Essais et traitements4050Données cliniques et programmes
Recherches et trouvailles21Pipeline scientifique
Publications4595Références reliées aux maladies
Pistes exploratoires0Hypothèses non validées
8666 résultats correspondants · 41 visibles sur cette page dans le périmètre Toutes les maladies
Niveau clinique

Études et traitements 4050

Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.

Molécule / élément Maladie / population Objectif Phase / stade Statut / preuve Mécanisme / résumé Source Détail
Prednisone NCT01169597 · Short Term Efficacy of a Starting Dose of 12.5 mg of Prednisone in Polymyalgia R… Myopathies À vérifier Phase 4 COMPLETED The purpose of this study is to evaluate the efficacy and tolerability of… À vérifier ClinicalTrials.gov 2026-07-29 15:50:58 Détail
Radial extracorporeal shock wave therapy (rESWT) NCT02596659 · Effectiveness of Radial Extracorporeal Shockwave Therapy on Tennis Elbow Myopathies Immunomodulation · Traitement symptomatique NA COMPLETED Background: Tennis elbow, also known as lateral epicondylitis, is the infl… À vérifier ClinicalTrials.gov 2026-07-29 15:50:58 Détail
Rehabilitation in Muscular Dystrophies From the Hospital Facility to… NCT06378203 · NCT06378203 Myopathies À vérifier NA UNKNOWN Until twenty years ago physical exercise in muscular dystrophies was consi… À vérifier ClinicalTrials.gov 2026-07-29 15:50:58 Détail
SRP-9003 NCT05876780 · A Gene Transfer Single Dose Study to Evaluate the Safety, Tolerability and Effic… Myopathies À vérifier Phase 1 ACTIVE_NOT_RECRUITING The primary purpose of this study is to evaluate the safety of SRP-9003 an… À vérifier ClinicalTrials.gov 2026-07-29 15:50:58 Détail
A Collaborative Palliative and Leukemia Care Model for Patients With… NCT03310918 · NCT03310918 Cancer Traitement symptomatique NA ACTIVE_NOT_RECRUITING This research study is evaluating the impact a collaborative palliative ca… À vérifier ClinicalTrials.gov 2026-07-29 15:50:57 Détail
Adefovir Dipivoxil and Lamivudine NCT00455091 · A Phase III Study in Post-operative HBV-related Hepatocellular Carcinoma Cancer À vérifier À vérifier TERMINATED Research Objective and Study End Points To evaluate the anti-HBV as well a… À vérifier ClinicalTrials.gov 2026-07-29 15:50:57 Détail
BeSMART — SMART Technology to Promote Heart Health in Midlife Adults NCT03724474 · NCT03724474 Hypertension artérielle À vérifier NA UNKNOWN This study aims to increase weekly minutes of moderate-to-vigorous physica… À vérifier ClinicalTrials.gov 2026-07-29 15:50:57 Détail
Dose escalated, accelerated, hypofractionated radiotherapy NCT00938418 · Hypofractionated Intensity Modulated Chemoradiotherapy to Treat Locally Advanced… Cancer À vérifier Phase 2 UNKNOWN Locally advanced non-small cell lung cancer can be treated successfully wi… À vérifier ClinicalTrials.gov 2026-07-29 15:50:57 Détail
doublepres — The Diagnosis and Treatment of Resistant Hypertension, t… NCT01703780 · NCT01703780 Hypertension artérielle À vérifier À vérifier UNKNOWN Hypertension is still one of the major preventable risk factor for cardiov… À vérifier ClinicalTrials.gov 2026-07-29 15:50:57 Détail
Effect of Palifermin on Skin Tumors in Patients Undergoing Bone Marro… NCT00610818 · NCT00610818 Cancer Immunomodulation · Traitement symptomatique À vérifier TERMINATED We are approaching you to participate in this study because you are taking… À vérifier ClinicalTrials.gov 2026-07-29 15:50:57 Détail
Improving Blood Pressure Control in End-Stage Renal Disease Through a… NCT01052220 · NCT01052220 Hypertension artérielle À vérifier NA COMPLETED The major purpose of this quantitative study is to determine if a 3 month… À vérifier ClinicalTrials.gov 2026-07-29 15:50:57 Détail
Integrating Targeted MedlinePlus Health Prescriptions Into Clinic Pra… NCT00634608 · NCT00634608 Hypertension artérielle À vérifier NA COMPLETED The specific aim of this proposed project is to implement a standard proce… À vérifier ClinicalTrials.gov 2026-07-29 15:50:57 Détail
Isolated Limb Infusion NCT04332874 · A Study of Pembrolizumab Plus Local Chemotherapy Using Isolated Limb Infusion (I… Cancer À vérifier Phase 2 RECRUITING The purpose of this study is to find out whether giving the study drug pem… À vérifier ClinicalTrials.gov 2026-07-29 15:50:57 Détail
Magnetic Resonance Imaging for Evaluating Kidney Function NCT00006173 · NCT00006173 Hypertension artérielle À vérifier À vérifier COMPLETED Renovascular hypertension (RVH) is a potentially curable disease affecting… À vérifier ClinicalTrials.gov 2026-07-29 15:50:57 Détail
myoma removal NCT00898170 · Effect of Myoma Removal on Blood Pressure and Erythropoetin Level Hypertension artérielle À vérifier NA COMPLETED The effect of myoma removal was studied on 28 patients with hypertension a… À vérifier ClinicalTrials.gov 2026-07-29 15:50:57 Détail
Paradise Ultrasound Renal Denervation Treatment NCT06297291 · US GPS — Global Paradise System US Post Approval Study Hypertension artérielle À vérifier À vérifier RECRUITING The objective of the Global Paradise® System US Post Approval Study (US GP… À vérifier ClinicalTrials.gov 2026-07-29 15:50:57 Détail
Randomized Trial of the Impact of Body Scanning and Intensive Behavio… NCT03392350 · NCT03392350 Hypertension artérielle À vérifier NA COMPLETED We evaluated the effectiveness of a combination of a comprehensive health… À vérifier ClinicalTrials.gov 2026-07-29 15:50:57 Détail
Sacubitril/valsartan NCT05545059 · Effects and Safety of Sacubitril/Valsartan on Refractory Hypertension Hypertension artérielle À vérifier Phase 3 UNKNOWN Resistant hypertension (RH) accounted for a considerable proportion of pat… À vérifier ClinicalTrials.gov 2026-07-29 15:50:57 Détail
Telemedicine NCT06524180 · TEACH — Can TElemedicine System Replace Doctor Consultations to Achieve Non-infe… Hypertension artérielle À vérifier NA RECRUITING The goal of this clinical trial is to evaluate whether patients assigned t… À vérifier ClinicalTrials.gov 2026-07-29 15:50:57 Détail
Telmisartan NCT00274118 · DETAIL Study: Diabetes Exposed to Telmisartan and Enalapril Hypertension artérielle À vérifier Phase 3 COMPLETED To conduct a proof of concept study in patients with mild to moderate Alzh… À vérifier ClinicalTrials.gov 2026-07-29 15:50:57 Détail
Découverte scientifique

Recherches et trouvailles 21

Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.

Molécule / élément Maladie / population Objectif Phase / stade Statut / preuve Mécanisme / résumé Source Détail
4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation Sclérose latérale amyotrophique Neuroprotection · Immunomodulation Découverte fondamentale Exploratoire Modulation immunométabolique de la microglie · NRF2 / inflammation microgl… Piste mécanistique visant à reprogrammer la réponse inflammatoire de la microglie. Le lien avec la SLA reste exploratoi… Revue scientifique 2024-07-01 Détail
Bibliographie

Publications 4595

Références bibliographiques de la base locale et accès à leur source originale.

Molécule / élément Maladie / population Objectif Phase / stade Statut / preuve Mécanisme / résumé Source Détail
Effects of testosterone-augmented multimodal exercise intervention in… Whole-body Electrical Muscle Stimulation Exercise · PMID 41988780 Myasthénie À vérifier Publication PubMed Voir la publication source Spinal cord injury (SCI) leads to profound muscle atrophy, aerobic deconditioning, and metabolic dysfunction. Exercise-… The Journal of clinical endocrinology and metabolism 2026-09-20 04:37:05 Source
Feasibility and acceptability of whole-body electromyostimulation in… Whole-body Electrical Muscle Stimulation Exercise · PMID 42464389 Myasthénie À vérifier Publication PubMed Voir la publication source Evidence on the effectiveness of electromyostimulation (EMS) has been reported in pulmonary rehabilitation, but the ben… Pilot and feasibility studies 2026-09-20 04:37:05 Source
Vestibular contributions adapt to the balance strategies adopted duri… Whole-body Electrical Muscle Stimulation Exercise · PMID 42616645 Myasthénie À vérifier Publication PubMed Voir la publication source Vestibular contributions during walking are not uniform, but vary with gait phase, muscle group, and balance demands. M… Journal of neurophysiology 2026-09-20 04:37:05 Source
Clinical efficacy of abdominal moxibustion at the Zhongji (CV3) in co… Yangyin Roujin Decoction · PMID 42015783 Myopathies Neuroprotection · Traitement symptomatique Publication PubMed Voir la publication source To investigate the clinical effect of abdominal moxibustion at the Zhongji (CV3) combined with Yiqi Tonglin Yangyin dec… Journal of traditional Chinese medicine = Chung i tsa… 2026-09-20 04:37:03 Source
Yiqi Huoxue Yangyin Decoction Ameliorates Diabetic Nephropathy by Tar… Yangyin Roujin Decoction · PMID 42713045 Myopathies À vérifier Publication PubMed Voir la publication source This study aimed to investigate the protective effects and underlying mechanisms of Yiqi Huoxue Yangyin Decoction (YHY)… Diabetes, metabolic syndrome and obesity : targets and… 2026-09-20 04:37:03 Source
Yiqi Huoxue Yangyin Decoction attenuates diabetic nephropathy in mice… Yangyin Roujin Decoction · PMID 42016924 Myopathies Thérapie génique Publication PubMed Voir la publication source Diabetic nephropathy (DN) is a major complication of diabetes with limited therapeutic options. Yiqi Huoxue Yangyin Dec… Frontiers in pharmacology 2026-09-20 04:37:03 Source
Barcoded oligonucleotide system (BOLT) for targeted organ delivery. Immunotherapy · PMID 42733790 Cancer À vérifier Publication PubMed Voir la publication source The therapeutic potential of oligonucleotides (oligos) is limited by insufficient delivery to extrahepatic tissues. In… Bioactive materials 2026-09-20 04:36:56 Source
Dual metabolic checkpoint blockade a 3D-Printed metalloplatform remod… Immunotherapy · PMID 42724565 Cancer Immunomodulation Publication PubMed Voir la publication source The immunosuppressive tumor microenvironment limits the efficacy of therapies that target metabolism. Here we show a st… Bioactive materials 2026-09-20 04:36:56 Source
Oligosaccharide adjuvant-deferred antigen endocytosis promotes cross-… Immunotherapy · PMID 42751513 Cancer Immunomodulation · Thérapie génique Publication PubMed Voir la publication source Antigen cross-presentation by dendritic cells (DCs) is essential for inducing cytotoxic immune responses, which are cru… Bioactive materials 2026-09-20 04:36:56 Source
Feasibility and safety of early discharge after robot-assisted uro-on… Digital care pathway for hypertension · PMID 42671715 Hypertension artérielle À vérifier Publication PubMed Voir la publication source Early discharge after robot-assisted uro-oncologic surgery remains limited by concerns regarding patient safety and the… Journal of robotic surgery 2026-09-20 04:36:49 Source
HomeSafe: Postpartum Hypertensive Care Enabled by Electronic Health R… Digital care pathway for hypertension · PMID 41707683 Hypertension artérielle À vérifier Publication PubMed Voir la publication source The objective is to present stepwise refinements to , an Epic-tethered, population-health-coordinated postpartum pathwa… American journal of perinatology 2026-09-20 04:36:49 Source
Nutraceutical and functional food: efficacy against metabolic disorde… Digital care pathway for hypertension · PMID 42603698 Hypertension artérielle Neuroprotection · Immunomodulation Publication PubMed Voir la publication source The growing global emphasis on health consciousness has significantly increased demand for traditional and complementar… Journal of advanced research 2026-09-20 04:36:49 Source
Community-engaged design of a virtual diabetes prevention program int… Asynchronous communication with nurse · PMID 42288862 Hypertension artérielle À vérifier Publication PubMed Voir la publication source The Diabetes Prevention Program (DPP) is an evidence-based approach to prevent Type 2 Diabetes (T2D), the leading cause… BMC health services research 2026-09-20 04:36:48 Source
Evolving Lung Cancer Navigator Practice Through Targeted Professional… Asynchronous communication with nurse · PMID 42463006 Cancer À vérifier Publication PubMed Voir la publication source Lung cancer remains the leading cause of cancer deaths worldwide, and it has persistent disparities in detection, treat… Chest 2026-09-20 04:36:48 Source
Mass casualty training for prehospital and emergency providers in Kig… Asynchronous communication with nurse · PMID 42751142 Hypertension artérielle À vérifier Publication PubMed Voir la publication source A mass casualty incident (MCI) occurs when the number of patients exceeds available healthcare resources, placing signi… African journal of emergency medicine : Revue africain… 2026-09-20 04:36:48 Source
Innovating a Teach-Back Model for Community Health Workers Led Health… Health Literacy Project · PMID 40194526 Épilepsie À vérifier Publication PubMed Voir la publication source From 2021 to 2023, the City of Albuquerque, the University of New Mexico (UNM) Office for Community Health, the UNM Hos… Health literacy research and practice 2026-09-20 04:36:34 Source
Carotid intima-media thickness may be an early biomarker for cardiova… Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy · PMID 41026111 Épilepsie À vérifier Publication PubMed Voir la publication source To assess early signs of atherosclerosis following long-term treatment with the ketogenic diet therapy due to concerns… Epilepsia open 2026-09-20 04:36:33 Source
Impact of low-carbohydrate diet on health status: an umbrella review. Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy · PMID 39385794 Cancer À vérifier Publication PubMed Voir la publication source The prevalence of diet-related non-communicable diseases has increased. A low-carbohydrate diet (LCDs) is one of the mo… Frontiers in nutrition 2026-09-20 04:36:33 Source
The effect of anti-seizure medications on lipid values in adults with… Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy · PMID 37244221 Épilepsie À vérifier Publication PubMed Voir la publication source Certain anti-seizure medications (ASMs) adversely impact lipid values. Here, we explored the impact of ASMs on lipid va… Epilepsy & behavior : E&B 2026-09-20 04:36:33 Source
Possible role of locus coeruleus neuronal loss in age-related memory… The Role of the Locus Coeruleus in Age-related Distractibility · PMID 37694113 Maladie d’Alzheimer Immunomodulation Publication PubMed Voir la publication source Aging is associated with a decline in cognitive abilities, including memory and attention. It is generally accepted tha… Frontiers in neuroscience 2026-09-20 04:36:30 Source
Exploration — prudence

Pistes exploratoires 0

Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.

Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
Molécule / élément Maladie / population Objectif Phase / stade Statut / preuve Mécanisme / résumé Source Détail
Aucune piste exploratoire ne correspond aux filtres.