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Migraine
Un même point d’entrée pour les études cliniques, les découvertes scientifiques, les publications et les pistes exploratoires présentes dans Biomedical Watch.
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1236 résultats correspondants
· 45 visibles sur cette page
dans le périmètre Migraine
Niveau clinique
Études et traitements 570
Interventions, programmes et essais cliniques rattachés au périmètre sélectionné.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Monoclonal antibody anti-CGRP NCT06459648 · PREDI-CGRP — Study for Prevent Chronification Migraine Through Prediction of Res… | Migraine | À vérifier | À vérifier | RECRUITING | Being able to predict each patients response to a specific treatment can m… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:08 | Détail |
| Serotonergic Psychedelic NCT06624137 · Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics | Migraine | Thérapie génique | À vérifier | TERMINATED | This is an observational study which does NOT directly administer a psyche… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:08 | Détail |
| MRI NCT05654012 · Migraine in Adolescents | Migraine | Remyélinisation · Thérapie génique | Non applicable | RECRUITING | The cognitive disorders of adult forms of myotonic dystrophies type 1 are… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:07 | Détail |
| Psilocybin NCT06464367 · Mechanistic Studies of Psilocybin in Headache Disorders | Migraine | À vérifier | Phase 1 | RECRUITING | This study aims to study the feasibility of psilocybin therapy for patient… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:07 | Détail |
| Rimegepant NCT06641466 · A Study to Learn About the Study Medicine Called Rimegepant in Women When Used f… | Migraine | À vérifier | Phase 3 | RECRUITING | The purpose of this study is to evaluate safety and tolerability of BHV-30… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:07 | Détail |
| Tear Biomarkers for Migraine NCT07690696 · NCT07690696 | Migraine | À vérifier | À vérifier | NOT_YET_RECRUITING | The goal of this observational monocentric study is to investigate tear an… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:07 | Détail |
| Thermal stimuli NCT05738213 · IHS — Puberty, Sex Hormones and Pain Sensitivity in Adolescents With Migraine | Migraine | Traitement symptomatique | Non applicable | ACTIVE_NOT_RECRUITING | The purpose of this research study is to investigate the relationships bet… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:07 | Détail |
| Thermal stimuli NCT06785129 · EMC — Endometriosis and Migraine | Migraine | Traitement symptomatique | À vérifier | RECRUITING | The purpose of this research study is to investigate the relationships bet… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:07 | Détail |
| Yangxue Qingnao Granules (Pills) NCT05334927 · CHAIRS — China HeadAche DIsorders RegiStry | Migraine | À vérifier | À vérifier | RECRUITING | It is planned to include 10000 patients. In the China HeadAche DIsorders R… À vérifier | ClinicalTrials.gov 2026-08-13 14:28:07 | Détail |
| Transcranial Direct Current stimulation NCT06401928 · Electrical Brain Stimulation for Treatment of Secondary Symptoms in Multiple Scl… | Sclérose en plaques | Traitement symptomatique | Non applicable | COMPLETED | Migraine is a common, heterogeneous neurological disorder affecting approx… À vérifier | ClinicalTrials.gov 2026-08-13 14:27:41 | Détail |
| Anodal Transcranial direct current stimulation NCT01752439 · Effects of Transcranial Direct Current Stimulation in Refractory Chronic Migrain… | Migraine | À vérifier | Non applicable | UNKNOWN | This research is being done to determine whether transcranial direct curre… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| BOTOX NCT00660192 · Investigation of Efficacy and Safety of Botulinum Toxin A (Botox-Allergan Inc) i… | Migraine | Thérapie génique | Phase 2 | COMPLETED | Migraine is a neurological disease characterized by moderate or severe hea… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| Dexamethasone, Lidocaine, Thiamine cohort NCT03220113 · Treatment of Chronic Migraine Headaches. | Migraine | Traitement symptomatique | Phase 1 | UNKNOWN | The purpose of the study is assessment of the safety and efficacy of the D… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| Erenumab Auto-Injector NCT04152434 · Treatment of Chronic Migraine With Erenumab Alone or as an Add on Therapy | Migraine | À vérifier | À vérifier | COMPLETED | Treatment of chronic migraineurs who have failed more than 3 preventive dr… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| ketamine infusion NCT06935552 · Ketamine and Lidocaine Infusion in Refractory Chronic Migraine | Migraine | Ralentissement de la progression · Traitement symptomatique | Phase 1 | NOT_YET_RECRUITING | Ketamine is a drug used for anesthesia but at low doses it is a very effec… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| Ketorolac NCT04353505 · Intra-arterial Sphenopalatine Ganglion Block for Patients With Refractory Headac… | Migraine | À vérifier | Phase 1 | WITHDRAWN | The purpose of this study is to evaluate the safety and efficacy of intra-… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| Lidocaine (drug) NCT07361549 · LIGHT 2 — Localized Injection of Lidocaine Via the Middle Meningeal Artery for I… | Migraine | Traitement symptomatique | Phase 2 | NOT_YET_RECRUITING | The main purpose of this study is to evaluate the effectiveness of a new t… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| Middle Meningeal Artery embolization NCT06029153 · FAST-EM — Efficacy and Safety of Middle Meningeal Artery Embolization for Treatm… | Migraine | À vérifier | Non applicable | COMPLETED | This is a prospective, multi-center, feasibility study to investigate safe… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| Precision NCT00747812 · PRISM UK — Study of Occipital Nerve Stimulation for Drug Refractory Migraine | Migraine | Thérapie génique | Phase 2 | TERMINATED | The purpose of this study is to evaluate the safety and effectiveness of a… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
| Precision NCT00286078 · Treatment for Migraines With an Implantable Device | Migraine | Thérapie génique | Non applicable | COMPLETED | The purpose of this study is to evaluate the safety and effectiveness of a… À vérifier | ClinicalTrials.gov 2026-08-13 14:17:17 | Détail |
Découverte scientifique
Recherches et trouvailles 0
Projets précliniques, publications émergentes et programmes de recherche suivis dans le pipeline.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Aucune trouvaille ne correspond aux filtres. | |||||||
Bibliographie
Publications 661
Références bibliographiques de la base locale et accès à leur source originale.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| From watershed to lagoon: Occurrence and ecological risk of paracetam… Paracetamol (acetaminophen) · PMID 42570042 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Pharmaceutical contamination in tropical coastal lagoons remains poorly characterized despite increasing anthropogenic… | Environmental science and pollution research internati… 2026-08-16 19:25:47 | Source |
| Metal nanocrystals and nanoclusters with paracetamol passivation and… Paracetamol (acetaminophen) · PMID 42483226 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Paracetamol (acetaminophen), being a well-used pharmaceutical drug, has several harmful health effects due to its overc… | Nanoscale advances 2026-08-16 19:25:47 | Source |
| Paracetamol-induced hepatic injury following intentional self-poisoni… Paracetamol (acetaminophen) · PMID 42573610 | Migraine | Ralentissement de la progression · Traitement symptomatique | Publication | PubMed | Voir la publication source Paracetamol (acetaminophen) overdose is a common cause of drug-induced hepatocellular injury and represents an importan… | Naunyn-Schmiedeberg's archives of pharmacology 2026-08-16 19:25:47 | Source |
| Knowledge About and the Use of Oral Nonsteroidal Anti-inflammatory Dr… NSAID (Nonsteroidal anti-inflammatory drugs) · PMID 38073919 | Migraine | Immunomodulation | Publication | PubMed | Voir la publication source The aims were to evaluate rheumatic disorder patients' knowledge of the side effects of nonsteroidal anti-inflammatory… | Cureus 2026-08-16 19:25:46 | Source |
| Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) Use Is Associated With… NSAID (Nonsteroidal anti-inflammatory drugs) · PMID 41293358 | Migraine | Immunomodulation · Traitement symptomatique | Publication | PubMed | Voir la publication source Background and objective Many patients across the United States suffer from migraines, which can be extremely painful a… | Cureus 2026-08-16 19:25:46 | Source |
| NSAID (nonsteroidal anti-inflammatory drugs) Induced Stevens Johnson… NSAID (Nonsteroidal anti-inflammatory drugs) · PMID 38469333 | Migraine | Immunomodulation | Publication | PubMed | Voir la publication source Stevens-Johnson Syndrome (SJS) is a severe and rare adverse drug reaction associated with significant morbidity and mor… | Toxicology reports 2026-08-16 19:25:46 | Source |
| Current Clinical Evidence on Nose-to-Brain Drug Delivery. triptans · PMID 42580438 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Intranasal delivery is increasingly recognised as a promising strategy for direct drug transport to the brain via the n… | Drug discovery today 2026-08-16 19:25:45 | Source |
| Efficacy analysis of combined nerve combing and decompression for occ… triptans · PMID 42003361 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source This study set occipital pain improvement as the primary endpoint, and overall headache relief, migraine index, medicat… | Annals of medicine 2026-08-16 19:25:45 | Source |
| A full-spectrum aqueous extract of black cardamom () improves focus/a… Caffeine (200 mg) · PMID 42027681 | Migraine | Traitement symptomatique · Thérapie génique | Publication | PubMed | Voir la publication source Interest is increasing in natural, plant-based, food-grade nootropics that deliver sustained cognitive benefits without… | Frontiers in neuroscience 2026-08-16 19:25:42 | Source |
| Design and rationale of TROCADERO: A TRial Of Caffeine to Alleviate D… Caffeine (200 mg) · PMID 26385029 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Ticagrelor treatment has the side effect of increased incidence of dyspnea. Adenosine-induced dyspnea is augmented by t… | American heart journal 2026-08-16 19:25:42 | Source |
| A scheme to tackle the dilemma from hepatoma cells under doxorubicin-… Metoclopramide · PMID 42482449 | Migraine | À vérifier | Publication | PubMed | Voir la publication source The aim of this study was to investigate key target(s), mechanism(s) from hepatoma cells in harsh doxorubicin-resistant… | Artificial cells, nanomedicine, and biotechnology 2026-08-16 19:25:39 | Source |
| Comprehensive MRI analysis of olfactory bulb morphology and olfactory… Understanding the Pathophysiology of Migraine Pain · PMID 42162730 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source This study aimed to provide a comprehensive MRI-based assessment of olfactory bulb (OB) morphology and olfactory sulcus… | Neuroscience 2026-08-16 19:25:39 | Source |
| Pharmaceutical policy and off-label prescribing in pregnancy: A popul… Metoclopramide · PMID 42281148 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Nausea and vomiting in pregnancy is highly prevalent and can significantly impact pregnant women's quality of life. Des… | Acta obstetricia et gynecologica Scandinavica 2026-08-16 19:25:39 | Source |
| Receptor-Targeted Antiemetic Strategies in Cats: A Systematic Review… Metoclopramide · PMID 42599757 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Emesis is a common adverse effect in cats receiving alpha-2 adrenergic agonists and opioids and may compromise perioper… | Veterinary medicine and science 2026-08-16 19:25:39 | Source |
| The influence of chronotype on pain: a systematic review and meta-ana… Understanding the Pathophysiology of Migraine Pain · PMID 42153471 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Sleep and circadian rhythms play critical roles in pain regulation, yet the influence of chronotype remains underexplor… | Pain 2026-08-16 19:25:39 | Source |
| [Migraine in men: biological, psychosocial and clinical characteristi… Understanding the Pathophysiology of Migraine Pain · PMID 41995752 | Migraine | Traitement symptomatique | Publication | PubMed | Voir la publication source Migraine affects 15% of the global population, with men being 2-3 times less frequently affected than women and are mar… | Schmerz (Berlin, Germany) 2026-08-16 19:25:39 | Source |
| Anti-inflammatory drugs disrupt granulosa cell homeostasis in vitro a… Ketoprofen · PMID 42308573 | Migraine | Immunomodulation | Publication | PubMed | Voir la publication source Granulosa cells (GCs) play a crucial role in maintaining follicular homeostasis and supporting the acquisition of oocyt… | Theriogenology 2026-08-16 19:25:38 | Source |
| Membrane-mediated mechanisms of NSAID-induced cardiotoxicity independ… Ketoprofen · PMID 42336296 | Migraine | Immunomodulation | Publication | PubMed | Voir la publication source Non-steroidal anti-inflammatory drugs (NSAIDs) are associated with cardiovascular adverse events that are not fully exp… | Toxicology and applied pharmacology 2026-08-16 19:25:38 | Source |
| Benzodiazepines use in Morocco: A nation wide consumption database st… Clorazepate Dipotassium · PMID 31759283 | Migraine | À vérifier | Publication | PubMed | Voir la publication source Although information exists regarding the rate of benzodiazepines (BZDs) use in different countries, little information… | Asian journal of psychiatry 2026-08-16 19:25:35 | Source |
| Effect of Clomethiazole Vs. Clorazepate on Hepatic Fat and Serum Tran… Clorazepate Dipotassium · PMID 36562601 | Migraine | Neuroprotection | Publication | PubMed | Voir la publication source Alcohol-associated liver disease (ALD) is a global health problem caused, among other factors, by oxidative stress from… | Alcohol and alcoholism (Oxford, Oxfordshire) 2026-08-16 19:25:35 | Source |
Exploration — prudence
Pistes exploratoires 5
Rapprochements mécanistiques et hypothèses de recherche : ils ne constituent pas une preuve d’efficacité ni une recommandation thérapeutique.
Hypothèses non validéesÀ confirmer par des travaux précliniques, cliniques et une revue scientifique indépendante.
| Molécule / élément | Maladie / population | Objectif | Phase / stade | Statut / preuve | Mécanisme / résumé | Source | Détail |
|---|---|---|---|---|---|---|---|
| Bavisant BRAVEinMS — Bavisant | Migraine | Remyélinisation · Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Antagonisme du récepteur H3 de l’histamine Bavisant est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migra… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| Tol-MP Tol-MP — tolérance immunitaire spécifique de la myéline | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Microparticules biodégradables chargées en rapamycine et fonctionnalisées… Tol-MP est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pour Migrain… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| SetPoint System SetPoint System — SetPoint Medical | Migraine | Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | re ApplicationsPublicationsCompanyCareersNewsGet startedGet startedNewsThe… SetPoint System est étudié dans Sclérose en plaques et documente plusieurs axes biologiques pouvant être pertinents pou… | Rapprochement Biomedical Watch · Sclérose en plaques | Détail |
| 4-octyl itaconate et dérivés Dérivés de l’itaconate — neuroinflammation | Migraine | Neuroprotection · Immunomodulation | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation immunométabolique de la microglie 4-octyl itaconate et dérivés est étudié dans Sclérose latérale amyotrophique et documente plusieurs axes biologiques po… | Rapprochement Biomedical Watch · Sclérose latérale amy… | Détail |
| N-PPG N-PPG — modulation métabolique cérébrale | Migraine | Remyélinisation indirecte / réparation · Neuroprotection | Hypothèse exploratoire | Rapprochement automatique non validé | Modulation métabolique et mitohormèse N-PPG est étudié dans Maladie de Huntington et documente plusieurs axes biologiques pouvant être pertinents pour Migrai… | Rapprochement Biomedical Watch · Maladie de Huntington | Détail |