University of Manitoba — Biomedical Watch V2

Traitements2programmes

Essais2liés

Publications2liées

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Traitements

2

Molécule	Indication / population	Phase	Objectif	Pays	Résultat
MPL-001Chronic headaches are a major cause of disability among adolescents. Cannabis products have supported the management of headaches in adults and may play a role in pediatric chronic pain. We propose a multisite, open-label, tolerability study conducted across three centers in Canada of Cannabidiol-enriched Cannabis Herbal Extract in adolescents (ages 14 to 17 years old) with chronic headaches. The study includes a one month baseline assessment, four months of escalating treatment doses and a weaning period. Our primary outcome is tolerability defined as the number and severity of reported adverse events.	Migraine	Phase 2	Traitement symptomatique	Canada	À vérifier
MPL-001Chronic headaches are a major cause of disability among adolescents. Cannabis products have supported the management of headaches in adults and may play a role in pediatric chronic pain. We propose a multisite, open-label, tolerability study conducted across three centers in Canada of Cannabidiol-enriched Cannabis Herbal Extract in adolescents (ages 14 to 17 years old) with chronic headaches. The study includes a one month baseline assessment, four months of escalating treatment doses and a weaning period. Our primary outcome is tolerability defined as the number and severity of reported adverse events.	Migraine	Phase 2	Traitement symptomatique	Canada	À vérifier

Essais cliniques

2

Molécule	Indication / population	Phase	NCT	Titre	Statut
paroxetine	SEP	Phase 3	NCT00291148	Neuropathic Pain Assessment Comparing Pregabalin and Paroxetine in Management of MS-induced Neuropathic Pain	COMPLETED
MPL-001	Migraine	Phase 2	NCT05337033	Cannabis for Chronic Headaches in Adolescents: the CAN-CHA Trial	RECRUITING

Publications

2

Molécule	Indication / population	Titre	Journal	Date
MPL-001		A multi-centre, tolerability study of a cannabidiol-enriched Cannabis Herbal Extract for chronic headaches in adolescents: The CAN-CHA protocol.	PloS one
MPL-001		Cannabidiol to reduce persistent post-surgical pain following total knee arthroplasty: protocol for a multi-centre, randomized, controlled pilot trial.	Pilot and feasibility studies