University of Kansas Medical Center — Biomedical Watch V2

Traitements10programmes

Essais5liés

Publications12liées

SourceDBlocale

Traitements

10

Molécule	Indication / population	Phase	Objectif	Pays	Résultat
ActivPALThe purpose of this study is to determine whether the researchers can help people change the amount of time they spend in sitting activities and whether this change might improve health outcomes.	Alzheimer	NA	À vérifier	United States	À vérifier
CareFit DS/AD — Adapting RDAD for DSThe goal of this clinical trial is to observe feasibility and initial efficacy of a remotely delivered exercise and dementia caregiving intervention in older adults with Down syndrome and their caregivers.	Alzheimer	Non applicable	À vérifier	United States	À vérifier
High Fidelity Fixed-Base SimulatorThe use of simulators to retrain driving skills of patients with stroke, Parkinson's disease (PD), or multiple sclerosis (MS) is very limited because of cost, space required, and incidence of simulator sickness in high fidelity simulators. The Principal investigator recently developed a low cost low fidelity portable driving simulator (PDS). In this pilot study, the study team will (1) determine the ease of use and occurrence of simulator sickness while operating the low fidelity PDS in a clinic setting and (2) the efficacy of the low fidelity PDS to reproduce the benefits from retraining impaired driving skills of stroke survivors in a high-fidelity simulator. Participants: 30 participants, separated according to neurological condition including stroke, PD, or MS, will be randomly allocated to either the PDS or fixed-base high-fidelity simulator training. Each participant will undergo a pre-training evaluation, five hours of designated training and a post-training assessment, similar to the pre-training evaluation. Data will be analyzed according to study aims. The investigators hypothesize that the simple set up of the PDS will make it easier to use and better decrease the incidence of simulator sickness that typically leads to stopping therapy than the high-fidelity simulator. The investigators hypothesize that improvements in lane maintenance, adherence to speed limits, reaction to traffic lights, and overall reaction time after training using the PDS will not be significantly different from improvements observed after training using the high-fidelity driving simulator.	Parkinson, SEP	Non applicable	À vérifier	United States	À vérifier
Jawbone UpThe purpose of this study is to determine whether the researchers can help people change the amount of time they spend in sitting activities and whether this change might improve health outcomes.	Alzheimer	NA	À vérifier	United States	À vérifier
Low-Fidelity PDSThe use of simulators to retrain driving skills of patients with stroke, Parkinson's disease (PD), or multiple sclerosis (MS) is very limited because of cost, space required, and incidence of simulator sickness in high fidelity simulators. The Principal investigator recently developed a low cost low fidelity portable driving simulator (PDS). In this pilot study, the study team will (1) determine the ease of use and occurrence of simulator sickness while operating the low fidelity PDS in a clinic setting and (2) the efficacy of the low fidelity PDS to reproduce the benefits from retraining impaired driving skills of stroke survivors in a high-fidelity simulator. Participants: 30 participants, separated according to neurological condition including stroke, PD, or MS, will be randomly allocated to either the PDS or fixed-base high-fidelity simulator training. Each participant will undergo a pre-training evaluation, five hours of designated training and a post-training assessment, similar to the pre-training evaluation. Data will be analyzed according to study aims. The investigators hypothesize that the simple set up of the PDS will make it easier to use and better decrease the incidence of simulator sickness that typically leads to stopping therapy than the high-fidelity simulator. The investigators hypothesize that improvements in lane maintenance, adherence to speed limits, reaction to traffic lights, and overall reaction time after training using the PDS will not be significantly different from improvements observed after training using the high-fidelity driving simulator.	Parkinson, SEP	Non applicable	À vérifier	United States	À vérifier
TDAD — Therapeutic Diets in Alzheimer's DiseaseBy doing this study, researchers hope to learn how the ketogenic and Therapeutic Lifestyles Changes diets affect cognition in patients with Alzheimer's disease.	Alzheimer	Non applicable	À vérifier	United States	À vérifier
Jawbone UpThe purpose of this study is to determine whether the researchers can help people change the amount of time they spend in sitting activities and whether this change might improve health outcomes.	Alzheimer	NA	À vérifier	United States	À vérifier
Low-Fidelity PDSThe use of simulators to retrain driving skills of patients with stroke, Parkinson's disease (PD), or multiple sclerosis (MS) is very limited because of cost, space required, and incidence of simulator sickness in high fidelity simulators. The Principal investigator recently developed a low cost low fidelity portable driving simulator (PDS). In this pilot study, the study team will (1) determine the ease of use and occurrence of simulator sickness while operating the low fidelity PDS in a clinic setting and (2) the efficacy of the low fidelity PDS to reproduce the benefits from retraining impaired driving skills of stroke survivors in a high-fidelity simulator. Participants: 30 participants, separated according to neurological condition including stroke, PD, or MS, will be randomly allocated to either the PDS or fixed-base high-fidelity simulator training. Each participant will undergo a pre-training evaluation, five hours of designated training and a post-training assessment, similar to the pre-training evaluation. Data will be analyzed according to study aims. The investigators hypothesize that the simple set up of the PDS will make it easier to use and better decrease the incidence of simulator sickness that typically leads to stopping therapy than the high-fidelity simulator. The investigators hypothesize that improvements in lane maintenance, adherence to speed limits, reaction to traffic lights, and overall reaction time after training using the PDS will not be significantly different from improvements observed after training using the high-fidelity driving simulator.	Parkinson	Non applicable	À vérifier	United States	À vérifier
CareFit DS/AD — Adapting RDAD for DSThe goal of this clinical trial is to observe feasibility and initial efficacy of a remotely delivered exercise and dementia caregiving intervention in older adults with Down syndrome and their caregivers.	Alzheimer	Non applicable	À vérifier	United States	À vérifier
TDAD — Therapeutic Diets in Alzheimer's DiseaseBy doing this study, researchers hope to learn how the ketogenic and Therapeutic Lifestyles Changes diets affect cognition in patients with Alzheimer's disease.	Alzheimer	Non applicable	À vérifier	United States	À vérifier

Essais cliniques

5

Molécule	Indication / population	Phase	NCT	Titre	Statut
TDAD — Therapeutic Diets in Alzheimer's Disease	Alzheimer	Non applicable	NCT03860792	TDAD — Therapeutic Diets in Alzheimer's Disease	COMPLETED
CareFit DS/AD — Adapting RDAD for DS	Alzheimer	Non applicable	NCT07425769	CareFit DS/AD — Adapting RDAD for DS	RECRUITING
Low-Fidelity PDS	Parkinson	Non applicable	NCT03969927	User-friendliness of a Portable Driving Simulator	COMPLETED
Memantine	Sclérose latérale amyotrophique	Phase 2	NCT02118727	Therapy in Amyotrophic Lateral Sclerosis (TAME)	COMPLETED
Jawbone Up	Alzheimer	NA	NCT02878486	ReST-MCI — Intervention to Reduce Sedentary Time	COMPLETED

Publications

12

Molécule	Indication / population	Titre	Journal	Date
ActivPAL		Comparison of activPAL and ActiGraph measured moderate to vigorous physical activity in people with COPD.	Physiological measurement
Jawbone Up		Minimally Invasive Resection of a Compound Odontoma Assisted by an Autonomous Oral Robot: A Technical Innovation.	Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
High Fidelity Fixed-Base Simulator		Mental workload associated with operating an agricultural sprayer: an empirical approach.	Journal of agricultural safety and health
ActivPAL		Behavioral and Contextual Patterns Derived From Ecological Momentary Assessment and Wearable Sensors and Their Associations With Health-Related Outcomes: WEALTH Cross-Sectional Study.	JMIR formative research
High Fidelity Fixed-Base Simulator		Pilots' visual scan patterns and situation awareness in flight operations.	Aviation, space, and environmental medicine
High Fidelity Fixed-Base Simulator		Psychophysiological responses to takeover requests in conditionally automated driving.	Accident; analysis and prevention
ActivPAL		Dog ownership and healthy brain aging: a pilot study.	PeerJ
ActivPAL		Prospective associations of diet quality and device-measured physical activity with midlife cognitive function: evidence from the 1970 British cohort study.	Journal of epidemiology and community health
Jawbone Up		Long-Term Bone Healing Using Autogenous Tooth Bone Graft Combined with rhBMP-2 after Enucleation of a Large Odontogenic Keratocyst: A Case Report.	Tissue engineering and regenerative medicine
Jawbone Up		Surgical Treatment of Maxillary Odontogenic Myxoma with Conservative Enucleation and Curettage: A Case Report.	Reports (MDPI)
ActivPAL		How Many Days Do We Need? Defining Reliable ActivPAL Monitoring Protocols for Distinct Movement Behaviors in Office Workers.	Scandinavian journal of medicine & science in sports
ActivPAL		Performance Evaluation of Device-Based Algorithms to Estimate Step Counts in Free-Living Adults Compared with Direct Observation.	Medicine and science in sports and exercise