Fiche société
Simone Spuler, MD
Traitements, essais et publications liés.
Traitements3programmes
Essais1liés
Publications20liées
SourceDBlocale
Traitements
3| Molécule | Indication / population | Phase | Objectif | Pays | Résultat |
|---|---|---|---|---|---|
| GenPHSat injection (Efficacy)This study is an investigator initiated first-in-human interventional open label phase 1/2a clinical trial investigating an ATMP in the orphan disease LGMD to evaluate safety and efficacy. | Myopathies | Phase 1 | À vérifier | À vérifier | |
| GenPHSat injection (Safety)This study is an investigator initiated first-in-human interventional open label phase 1/2a clinical trial investigating an ATMP in the orphan disease LGMD to evaluate safety and efficacy. | Myopathies | Phase 1 | À vérifier | À vérifier | |
| GenPHSat injection (Safety)This study is an investigator initiated first-in-human interventional open label phase 1/2a clinical trial investigating an ATMP in the orphan disease LGMD to evaluate safety and efficacy. | Myopathies | Phase 1 | Thérapie cellulaire | À vérifier |
Essais cliniques
1| Molécule | Indication / population | Phase | NCT | Titre | Statut |
|---|---|---|---|---|---|
| GenPHSat injection (Safety) | Myopathies | Phase 1 | NCT05588401 | Evaluating Safety and Efficacy of Autologous Gene-edited Muscle Stem Cells (GenPHSats-bASKet) | UNKNOWN |
Publications
20| Molécule | Indication / population | Titre | Journal | Date |
|---|---|---|---|---|
| GenPHSat injection (Safety) | Efficiency and Safety of Endoscopic Injection Sclerotherapy With Ligation for Esophageal Varices: A Retrospective Study. | DEN open | ||
| GenPHSat injection (Safety) | A Step-Up Underwater Endoscopic Mucosal Resection Strategy with Rescue Underwater Injection Endoscopic Mucosal Resection for Non-Pedunculated Colorectal Lesions. | DEN open | ||
| GenPHSat injection (Safety) | Beyond the first switch: multiple switching, cross-switching, and nocebo-aware implementation of biosimilars in real-world care in non-US health systems. | Expert opinion on biological therapy | ||
| GenPHSat injection (Safety) | Detection of antisense oligonucleotides from biological samples by ligase detection reaction using T4 RNA ligase 2. | BioTechniques | ||
| GenPHSat injection (Efficacy) | Combined α-lactalbumin hydrolysate and anti-VEGF agent treatment attenuates ventilator-induced lung injury by suppressing the NLRP3 inflammasome pathway. | Tissue & cell | ||
| GenPHSat injection (Efficacy) | The Pan-Salt-inducible Kinase Inhibitor YKL-06-061 Exerts Antidepressant-like Effects via Hippocampal CRTC1-CREB-BDNF Pathway Activation in Chronic Stress Models. | European journal of pharmacology | ||
| GenPHSat injection (Safety) | Intravitreal Steroid and Anti-VEGF in Macular Edema Secondary to Retinal Vein Occlusion. | Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti | ||
| GenPHSat injection (Safety) | Age outweighs route for AAV-PHP.eB transgene distribution via inner ear delivery. | Drug delivery and translational research | ||
| GenPHSat injection (Safety) | Beyond awareness: evaluating the impact of a hospital-wide, multi-station infection prevention and control (IPC) innovation campaign on core hospital infection control committee (HICC) performance metrics - a pre-post audit study. | GMS hygiene and infection control | ||
| GenPHSat injection (Safety) | Combined anti-VEGF and intravitreal dexamethasone treatment versus anti-VEGF alone for persistent diabetic macular edema: a comprehensive systematic review and meta-analysis. | Arquivos brasileiros de oftalmologia | ||
| GenPHSat injection (Efficacy) | Efficacy of perifracture site injections for pain control following distal radius and ankle fracture surgery: a meta-analysis of randomized controlled trials. | Journal of orthopaedic surgery and research | ||
| GenPHSat injection (Safety) | Denecimig (Mim8) prophylaxis once-every-2-weeks for hemophilia A with or without inhibitors - 26-week results from FRONTIER. | Blood advances | ||
| GenPHSat injection (Safety) | Long-term efficacy and safety of intra-articular corticosteroid injections in patients with knee osteoarthritis. | Expert opinion on drug safety | ||
| GenPHSat injection (Safety) | Effect of 37°C Pre-Warmed Versus Room Temperature Gadoxetic Acid Disodium Contrast Medium on Patient Comfort and Image Quality in Liver MRI: A Prospective, Double-Blind, Self-Controlled Before-and-After Study. | Journal of magnetic resonance imaging : JMRI | ||
| GenPHSat injection (Safety) | Safety and Efficacy of TrenibotulinumtoxinE for Moderate-to-Severe Glabellar Lines: A Phase 2b, Double-Blind, Placebo-Controlled, Dose-Escalation Study. | Aesthetic surgery journal | ||
| GenPHSat injection (Efficacy) | Ultrasound-guided platelet-rich plasma myofascial injection for chronic low back pain: a retrospective study. | BMC musculoskeletal disorders | ||
| GenPHSat injection (Safety) | EXPRESS: Ultrasound Enhances Glymphatic-Associated Solute Transport via Piezo1-Related Mechanotransduction in 5xFAD Mice. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism | ||
| GenPHSat injection (Safety) | EXPRESS: Comparing the Efficacy of Transmucosal and Subcutaneous Glucagon Administration in Response to Insulin-Induced Hypoglycemia in Healthy Cats. | Journal of feline medicine and surgery | ||
| GenPHSat injection (Safety) | Phase I/II Study of NGGT001 Gene Therapy for Bietti Crystalline Dystrophy. | Ophthalmology science | ||
| GenPHSat injection (Safety) | Unregulated Peptide Use in the Age of Biohacking: Digital Promotion, Gray-Market Access, and Emerging Public Health Risks. | Cureus |