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Traitements, essais et publications liés.
Traitements7programmes
Essais3liés
Publications6liées
SourceDBlocale
Traitements
7| Molécule | Indication / population | Phase | Objectif | Pays | Résultat |
|---|---|---|---|---|---|
| FocalOneThe objective of this study is to evaluate the clinical effectiveness and safety of treatment of prostate cancer in patients who have received a focal HIFU treatment using the Focal One medical device. | Cancer | À vérifier | À vérifier | Spain | À vérifier |
| HIFU (Focal One®)Deep invasive endometriosis (DIE) includes lesions of the rectosigmoid. Theses lesions are associated with painful symptoms that can alter quality of life. High Intensity Focused Ultrasound (HIFU) is a non-invasive ablative procedure using a high-intensity ultrasound probe to induce tissue devitalization using acoustic cavitation and thermal ablation. Focal One® is a transrectal HIFU device, which is validated to treat prostatic cancer. The primary objective of this clinical trial is to evaluate the ability of the Focal One® HIFU device to detect and target posterior DIE lesions with intestinal involvement. The secondary objectives are to perform a HIFU lesion, to evaluate morphological modifications of the nodule in post-therapeutic imaging scans, to assess evolution of gynecological symptoms, intestinal symptoms, and patients' quality of life after treatment by HIFU and to collect safety data. | Cancer | Non applicable | Traitement symptomatique | France | À vérifier |
| HIFU treatment in rectal EndometriosisRectal endometriosis (RE) induces lesions associated with painful symptoms that can alter quality of life. High Intensity Focused Ultrasound (HIFU) is a non-invasive ablative procedure using a high-intensity ultrasound probe to induce tissue devitalization using acoustic cavitation and thermal ablation. Focal One® is a transrectal HIFU device, which is validated to treat prostatic cancer. In this comparative, randomized, double blind study , the primary objective is to evaluate the efficacy of the HIFU treatment of rectal endometriosis with Focal One® HIFU device on the Acute Pelvic Pain 3 months after HIFU treatment, in comparison to a Sham group. | Cancer | Non applicable | Traitement symptomatique | France | À vérifier |
| SHAM HIFU procedureRectal endometriosis (RE) induces lesions associated with painful symptoms that can alter quality of life. High Intensity Focused Ultrasound (HIFU) is a non-invasive ablative procedure using a high-intensity ultrasound probe to induce tissue devitalization using acoustic cavitation and thermal ablation. Focal One® is a transrectal HIFU device, which is validated to treat prostatic cancer. In this comparative, randomized, double blind study , the primary objective is to evaluate the efficacy of the HIFU treatment of rectal endometriosis with Focal One® HIFU device on the Acute Pelvic Pain 3 months after HIFU treatment, in comparison to a Sham group. | Cancer | Non applicable | Traitement symptomatique | France | À vérifier |
| HIFU (Focal One®)Deep invasive endometriosis (DIE) includes lesions of the rectosigmoid. Theses lesions are associated with painful symptoms that can alter quality of life. High Intensity Focused Ultrasound (HIFU) is a non-invasive ablative procedure using a high-intensity ultrasound probe to induce tissue devitalization using acoustic cavitation and thermal ablation. Focal One® is a transrectal HIFU device, which is validated to treat prostatic cancer. The primary objective of this clinical trial is to evaluate the ability of the Focal One® HIFU device to detect and target posterior DIE lesions with intestinal involvement. The secondary objectives are to perform a HIFU lesion, to evaluate morphological modifications of the nodule in post-therapeutic imaging scans, to assess evolution of gynecological symptoms, intestinal symptoms, and patients' quality of life after treatment by HIFU and to collect safety data. | Cancer | Non applicable | Traitement symptomatique | France | À vérifier |
| FocalOneThe objective of this study is to evaluate the clinical effectiveness and safety of treatment of prostate cancer in patients who have received a focal HIFU treatment using the Focal One medical device. | Cancer | À vérifier | À vérifier | Spain | À vérifier |
| HIFU treatment in rectal EndometriosisRectal endometriosis (RE) induces lesions associated with painful symptoms that can alter quality of life. High Intensity Focused Ultrasound (HIFU) is a non-invasive ablative procedure using a high-intensity ultrasound probe to induce tissue devitalization using acoustic cavitation and thermal ablation. Focal One® is a transrectal HIFU device, which is validated to treat prostatic cancer. In this comparative, randomized, double blind study , the primary objective is to evaluate the efficacy of the HIFU treatment of rectal endometriosis with Focal One® HIFU device on the Acute Pelvic Pain 3 months after HIFU treatment, in comparison to a Sham group. | Cancer | Non applicable | Traitement symptomatique | France | À vérifier |
Essais cliniques
3| Molécule | Indication / population | Phase | NCT | Titre | Statut |
|---|---|---|---|---|---|
| HIFU treatment in rectal Endometriosis | Cancer | Non applicable | NCT05755958 | ENDO-HIFU-R2 — Evaluation of the Efficacy of HIFU Treatment on Rectal Endometriosis Symptoms. | ACTIVE_NOT_RECRUITING |
| FocalOne | Cancer | À vérifier | NCT06375629 | ES-HIFU, Prospective Data Collection of Patients Treated With Partial Gland HIFU Ablation for Prostate Cancer | TERMINATED |
| HIFU (Focal One®) | Cancer | Non applicable | NCT03613298 | Treatment by HIFU With Focal One® of Posterior Deep Infiltrating Endometriosis Lesions With Intestinal Involvement. | COMPLETED |
Publications
6| Molécule | Indication / population | Titre | Journal | Date |
|---|---|---|---|---|
| FocalOne | Evaluating indeterminate bone lesions and lymph nodes on PSMA-PET: a multidisciplinary consensus algorithm and 1-year implementation results. | European radiology | ||
| FocalOne | Reply to the Letter to the Editor: PRECISE-guided biopsy de-escalation during active surveillance requires cautious interpretation. | European radiology | ||
| FocalOne | Optimizing prostate biopsy decision making - (MUSIC-screen): A 1:1 randomized controlled trial comparing micro-ultrasound versus multiparametric magnetic resonance imaging for prostate cancer diagnosis. | Contemporary clinical trials | ||
| HIFU (Focal One®) | Dystonia before and after Unilateral High Intensity Focused Ultrasound Thalamotomy in Essential and Dystonic Tremor. | Movement disorders clinical practice | ||
| HIFU (Focal One®) | Dual-approach High-intensity Focused Ultrasound for Facial Contour Modulation and Submental Reduction. | Plastic and reconstructive surgery. Global open | ||
| HIFU (Focal One®) | Focal Therapy for Prostate Cancer: A Treatment Option Reserved for the Ideal Candi-date? | International braz j urol : official journal of the Brazilian Society of Urology |