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Ain Shams University
Traitements, essais et publications liés.
Traitements11programmes
Essais5liés
Publications16liées
SourceDBlocale
Traitements
11| Molécule | Indication / population | Phase | Objectif | Pays | Résultat |
|---|---|---|---|---|---|
| Caffeine (200 mg)Caffeine extracted from green tea to abort acute attack of Migraine | Migraine | Phase 4 | À vérifier | Egypt | À vérifier |
| Effects of Curcumin-Piperine Supplementation in FibromyalgiaThe goal of this clinical trail is to evaluate the effectiveness and safety of curcumin-piperine supplementation in patients with fibromyalgia over 3 months compared to placebo. Participants will: Be randomly assigned to receive either curcumin and piperine supplements or a placebo. Attend scheduled clinic visits for clinical assessments and blood sample collection. Complete study questionnaires before and after treatment time frame. The primary question the study aim to answer is: Does Curcumin-piperine supplementation reduce pain intensity by Visual Analog Scale (VAS), compared with placebo? The secondary questions this study aims to answer are: Does supplementation improve fibromyalgia disease impact and quality of life? Does supplementation improve inflammatory biomarkers and oxidative stress? Does supplementation improve insulin resistance? Is curcumin and piperine supplementation safe and well tolerated? | Myopathies | Phase 2 | Neuroprotection + Immunomodulation + Traitement symptomatique | Egypt | À vérifier |
| NSAID (Nonsteroidal anti-inflammatory drugs)Caffeine extracted from green tea to abort acute attack of Migraine | Migraine | Phase 4 | Immunomodulation | Egypt | À vérifier |
| Paracetamol (acetaminophen)Caffeine extracted from green tea to abort acute attack of Migraine | Migraine | Phase 4 | À vérifier | Egypt | À vérifier |
| trans nasal sphenopalatine ganglion blockThe purpose of the study is to compare Sphenopalatine ganglion block (SPGB) and aminophylline in the efficacy and safety management of PDPH. | SEP | Phase 4 | À vérifier | Egypt | À vérifier |
| triptansCaffeine extracted from green tea to abort acute attack of Migraine | Migraine | Phase 4 | À vérifier | Egypt | À vérifier |
| ultrasound guided Greater occipital nerve blockTo investigate the efficacy of Ultrasound guided Stellate Ganglion block in chronic resistant migraine patients in comparison to Greater Occipital Nerve Block correlating its effect to serum CGRP level. | Migraine | NA | À vérifier | Egypt | À vérifier |
| Ultrasound guided Stellate ganglion blockTo investigate the efficacy of Ultrasound guided Stellate Ganglion block in chronic resistant migraine patients in comparison to Greater Occipital Nerve Block correlating its effect to serum CGRP level. | Migraine | NA | À vérifier | Egypt | À vérifier |
| ultrasound guided Greater occipital nerve blockTo investigate the efficacy of Ultrasound guided Stellate Ganglion block in chronic resistant migraine patients in comparison to Greater Occipital Nerve Block correlating its effect to serum CGRP level. | Migraine | NA | À vérifier | Egypt | À vérifier |
| Caffeine (200 mg)Caffeine extracted from green tea to abort acute attack of Migraine | Migraine | Phase 4 | À vérifier | Egypt | À vérifier |
| Effects of Curcumin-Piperine Supplementation in FibromyalgiaThe goal of this clinical trail is to evaluate the effectiveness and safety of curcumin-piperine supplementation in patients with fibromyalgia over 3 months compared to placebo. Participants will: Be randomly assigned to receive either curcumin and piperine supplements or a placebo. Attend scheduled clinic visits for clinical assessments and blood sample collection. Complete study questionnaires before and after treatment time frame. The primary question the study aim to answer is: Does Curcumin-piperine supplementation reduce pain intensity by Visual Analog Scale (VAS), compared with placebo? The secondary questions this study aims to answer are: Does supplementation improve fibromyalgia disease impact and quality of life? Does supplementation improve inflammatory biomarkers and oxidative stress? Does supplementation improve insulin resistance? Is curcumin and piperine supplementation safe and well tolerated? | Myopathies | Phase 2 | Neuroprotection + Immunomodulation + Traitement symptomatique | Egypt | À vérifier |
Essais cliniques
5| Molécule | Indication / population | Phase | NCT | Titre | Statut |
|---|---|---|---|---|---|
| Aminophylline | SEP | Phase 4 | NCT05552404 | Postdural Puncture Headache Relief With Aminophylline and SPGB | COMPLETED |
| Melatonin | Lupus | Phase 2/3 | NCT07721324 | SLE — Effect of Melatonin Administration on Systemic Lupus Erythematosus Patients | NOT_YET_RECRUITING |
| Effects of Curcumin-Piperine Supplementation in Fibromyalgia | Myopathies | Phase 2 | NCT07753018 | Effects of Curcumin-Piperine Supplementation in Fibromyalgia | NOT_YET_RECRUITING |
| Caffeine (200 mg) | Migraine | Phase 4 | NCT07022496 | Assessment of Oral Caffeine Intake in Changing the Severity of Acute Migraine Attack Using VAS Score Among Patients Attending Headache and Neurology Outpatients Clinic of Ainshams University Hospitals | RECRUITING |
| ultrasound guided Greater occipital nerve block | Migraine | NA | NCT06662461 | Ultrasound Guided Block of Stellate Ganglion Versus Greater Occipital Nerve in Resistant Migraine and Correlation to Calcitonin Gene Related Peptide | RECRUITING |
Publications
16| Molécule | Indication / population | Titre | Journal | Date |
|---|---|---|---|---|
| Paracetamol (acetaminophen) | From watershed to lagoon: Occurrence and ecological risk of paracetamol in the Segara Anakan coastal ecosystem. | Environmental science and pollution research international | ||
| Paracetamol (acetaminophen) | Paracetamol-induced hepatic injury following intentional self-poisoning: a case report and therapeutic considerations. | Naunyn-Schmiedeberg's archives of pharmacology | ||
| Paracetamol (acetaminophen) | Metal nanocrystals and nanoclusters with paracetamol passivation and for paracetamol detection: a critical review. | Nanoscale advances | ||
| NSAID (Nonsteroidal anti-inflammatory drugs) | Knowledge About and the Use of Oral Nonsteroidal Anti-inflammatory Drugs Among Patients With Rheumatic Disorders in Saudi Arabia: A Cross-Sectional Study. | Cureus | ||
| NSAID (Nonsteroidal anti-inflammatory drugs) | NSAID (nonsteroidal anti-inflammatory drugs) Induced Stevens Johnson Syndrome in a 50-year-old woman: A case study. | Toxicology reports | ||
| NSAID (Nonsteroidal anti-inflammatory drugs) | Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) Use Is Associated With an Increased Risk of Femoral Osteonecrosis in Migraine Patients: A Retrospective, TriNetX Database-Based Study. | Cureus | ||
| triptans | Current Clinical Evidence on Nose-to-Brain Drug Delivery. | Drug discovery today | ||
| triptans | Efficacy analysis of combined nerve combing and decompression for occipital neuralgia based on the classification of neurovascular relationships. | Annals of medicine | ||
| Caffeine (200 mg) | Design and rationale of TROCADERO: A TRial Of Caffeine to Alleviate DyspnEa Related to ticagrelOr. | American heart journal | ||
| Caffeine (200 mg) | A full-spectrum aqueous extract of black cardamom () improves focus/alertness and executive function: a randomized, double-blinded, placebo- and active-controlled, comparative study in healthy working-class participants. | Frontiers in neuroscience | ||
| Ultrasound guided Stellate ganglion block | Ultrasound-guided stellate ganglion block for refractory sympathetically mediated arrhythmia following acute myocardial infarction: a tutorial and examples. | Frontiers in cardiovascular medicine | ||
| Ultrasound guided Stellate ganglion block | Preoperative Ultrasound-Guided Stellate Ganglion Block for Prevention of Postoperative Sore Throat After Thoracic Surgery: Study Protocol for a Randomized Controlled Trial. | Journal of pain research | ||
| ultrasound guided Greater occipital nerve block | Chronic migraine prophylaxis: Comparative study between ultrasound-guided greater occipital nerve block and medical treatment. | Clinical neurology and neurosurgery | ||
| Ultrasound guided Stellate ganglion block | Ultrasound-Guided Stellate Ganglion Block in Fibromyalgia: A Randomized, Single-Center, Single-Blind, Sham-Controlled Trial. | Pain research & management | ||
| ultrasound guided Greater occipital nerve block | Ultrasound-Guided Greater Occipital Nerve Block Across Headache Phenotypes: Outcomes and Determinants of Response in a Prospective Cohort. | Pain and therapy | ||
| ultrasound guided Greater occipital nerve block | Post-dural Puncture Headache During Bacteraemia: Successful Management With Combined Sphenopalatine Ganglion and Greater Occipital Nerve Blocks. | Cureus |