Clinical trials

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Études cliniques 214

Étude / NCT ⇅ Molécule ⇅ Maladie ⇅ Phase ⇅ Statut ⇅ Résultat ⇅ Sponsor ⇅ Pays / centres ⇅ Période ⇅ Détail
NCT05765006
CD19-CART(Relma-cel) for Moderate to Severe Active Systemic Lupus Eryth…
Relma-cel SEP Phase 1 UNKNOWN En attente / non publié Shanghai Ming Ju Biotechnology Co… China · Relma-cel Medical, Shanghai, China 2023-02-24 → 2025-12-30 Ouvrir
NCT07331467
Study of Ultra-Fast CD19 CAR-T Therapy for Refractory SLE
CD19 CAR-T cells SEP Phase 1 RECRUITING En attente / non publié Chongqing Precision Biotech Co., … China · Affiliated Drum Tower Hospital, Medical Schoo… 2026-01 → 2028-08 Ouvrir
NCT07260877
AERIS — A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Ph…
VENT-03 Lupus Phase 2 RECRUITING En attente / non publié Ventus Therapeutics U.S., Inc. United States, Bulgaria, France, Georgia, Hungary, Po… 2025-12-03 → 2027-03 Ouvrir
NCT05352919
EMERALD — A Study to Learn More About the Long-Term Safety of Litifilim…
Litifilimab Lupus Phase 3 ENROLLING_BY_INVITATION En attente / non publié Biogen United States, Argentina, Belgium, Brazil, Bulgaria, … 2022-06-10 → 2032-05-03 Ouvrir
NCT06434363
Phase I/II Study of AD-PluReceptor Plus Tafasitamab-cxix and Lymphodepl…
Tafasitamab Lupus Phase 1/2 RECRUITING En attente / non publié M.D. Anderson Cancer Center United States · MD Anderson Cancer Center, Houston, U… 2024-07-31 → 2030-12-31 Ouvrir
NCT07104344
Study of CM355 in Patients With Systemic Lupus Erythematosus
CM355 Lupus Non applicable ACTIVE_NOT_RECRUITING En attente / non publié Second Xiangya Hospital of Centra… China · Second Xiangya Hospital of Central South Univ… 2025-09-25 → 2027-09-01 Ouvrir
NCT04868838
Daratumumab to Treat Active Lupus Nephritis
Daratumumab Lupus Phase 2 ACTIVE_NOT_RECRUITING En attente / non publié Mayo Clinic United States · Mayo Clinic in Rochester, Rochester, … 2021-04-20 → 2027-01 Ouvrir
NCT03747159
SynBioSe-2 — Synergetic B-cell Immunomodulation in SLE - 2nd Study.
Belimumab Injection Lupus Phase 3 COMPLETED En attente / non publié Leiden University Medical Center Netherlands · HagaZiekenhuis, The Hague, Netherlands … 2018-10-01 → 2026-06-22 Ouvrir
NCT07829497
Pain Phenotyping of Rheumatic Diseases - An Observational Study
Bedside quantitative sensory test… Lupus À vérifier NOT_YET_RECRUITING En attente / non publié National Institute of Arthritis a… United States · National Institutes of Health Clinica… 2026-10-14 → 2036-06-15 Ouvrir
NCT07276958
A Study of LY4298445 in Healthy Participants and Participants With Syst…
LY4298445 Lupus Phase 1 RECRUITING En attente / non publié Eli Lilly and Company Australia, China, Japan · Anhui Provincial Hospital, … 2026-02-04 → 2028-03 Ouvrir
NCT07355218
A Study of Enpatoran in Participants With Cutaneous Manifestations of L…
Enpatoran Lupus Phase 3 RECRUITING En attente / non publié EMD Serono Research & Development… United States, Australia, Brazil, Bulgaria, Canada, C… 2026-04-01 → 2029-05-25 Ouvrir
NCT07332481
ELOWEN-1 — A Study of Enpatoran in Participants With Cutaneous Manifest…
Enpatoran Lupus Phase 3 RECRUITING En attente / non publié EMD Serono Research & Development… United States, Australia, Brazil, Bulgaria, France, G… 2026-03-10 → 2029-05-24 Ouvrir
NCT07629583
To Evaluate the Effects of Cevostamab in Participants With Systemic Lup…
Cevostamab Lupus Phase 1 RECRUITING En attente / non publié Genentech, Inc. France, Spain · Hopital Rangueil, Toulouse, France | … 2026-10-31 → 2030-03-29 Ouvrir
NCT06828042
Safety and Efficacy of Universal CD19-targeting CAR-γδT Cells in Refrac…
anti-CD19 CAR T cell therapy SEP Phase 1/2 RECRUITING En attente / non publié Peking University Third Hospital China · Peking University Third Hospital, Beijing, Ch… 2025-07-01 → 2027-12-31 Ouvrir
NCT07782450
A Study to Learn About a Medicine Called PF-08154225 in Participants Wi…
PF-08154225 Myopathies Phase 1/2 NOT_YET_RECRUITING En attente / non publié Pfizer Non communiqué 2026-11-19 → 2031-02-22 Ouvrir
NCT07844200
Bela-SLE — The Primary Objective of the Trial is to Evaluate the Effect…
belantamab mafodotin to the exist… Lupus Phase 2 NOT_YET_RECRUITING En attente / non publié Medical Association for the Study… Non communiqué 2027-02 → 2031-12 Ouvrir
NCT07038447
A Study of KITE-363 in Participants With Refractory Autoimmune Diseases
KITE-363 Lupus Phase 1 ENROLLING_BY_INVITATION En attente / non publié Kite, A Gilead Company United States, Australia, Canada, South Korea · ASAN … 2025-07-02 → 2030-09 Ouvrir
NCT05411016
A Study of KK4277 in Healthy Volunteers and Patients With Systemic Lupu…
KK4277 Lupus Phase 1 COMPLETED En attente / non publié Kyowa Kirin Co., Ltd. Japan, South Korea · Ajou University Hospital, Suwon,… 2022-08-03 → 2025-10-27 Ouvrir
NCT04643067
Lupus — Phase 1b/2a Study to Evaluate Safety and Efficacy of KPG-818 in…
KPG-818 low dose in phase 1b Lupus Phase 1/2 COMPLETED En attente / non publié Kangpu Biopharmaceuticals, Ltd. United States · Accurate Clinical Management, Houston… 2021-06-03 → 2023-06-29 Ouvrir
NCT07299422
A Study of SHR-2173 in Participants With Systemic Lupus Erythematosus
SHR-2173 injection Lupus Phase 2 RECRUITING En attente / non publié Guangdong Hengrui Pharmaceutical … China · Chinese Academy of Medical Sciences, Peking U… 2026-04-03 → 2028-11 Ouvrir
NCT07083349
NK510 Cell Therapy for Refractory Systemic Lupus Erythematosus
NK510 : allogeneic genetic modifi… Lupus Phase 1 TERMINATED En attente / non publié Base Therapeutics (Shanghai) Co.,… China · The First Affiliated Hospital of Anhui Medica… 2025-12-01 → 2026-04-01 Ouvrir
NCT07799116
CART-NEL — Study to Evaluate the Safety and Preliminary Efficacy of CD1…
TranspoCART19 Lupus Phase 1/2 RECRUITING En attente / non publié Instituto de Investigación Sanita… Spain · Clinica Universidad de Navarra, Pamplona, Spa… 2026-09-23 → 2030-09 Ouvrir
NCT07855302
CD19 CAR-T Therapy for Refractory Childhood-Onset Systemic Lupus Erythe…
SNUH-CD19-CAR-T Cells Lupus Phase 1 RECRUITING En attente / non publié Seoul National University Hospital South Korea · Seoul National University Hospital, Seo… 2026-09-14 → 2028-12 Ouvrir
NCT06133972
SIRIUS-SLE LTE — Phase 3 Extension Study to Evaluate Long-term Safety o…
Ianalumab Lupus Phase 3 RECRUITING En attente / non publié Novartis Pharmaceuticals United States, Argentina, Australia, Brazil, Bulgaria… 2024-05-21 → 2034-10-02 Ouvrir
NCT04976322
A Study to Evaluate the Safety and Tolerability of Dapirolizumab Pegol …
Dapirolizumab pegol Lupus Phase 3 ENROLLING_BY_INVITATION En attente / non publié UCB Biopharma SRL United States, Argentina, Belgium, Bulgaria, Canada, … 2021-07-27 → 2030-08-07 Ouvrir